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Volumn 19, Issue 1, 2005, Pages 185-190

The hepoxilin analog, PBT-3, inhibits growth of K-562 CML solid tumours in vivo in nude mice

Author keywords

Apoptosis; CML; Hepoxilin analogs; K 562; PBT 3

Indexed keywords

DNA; DRUG VEHICLE; HYDROXY FATTY ACID; IMATINIB; PBT 3; UNCLASSIFIED DRUG;

EID: 16244400473     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (25)
  • 1
    • 0021099524 scopus 로고
    • Arachidonic acid epoxides: Isolation and structure of 2 hydroxy epoxide intermediates in the formation of 8,11,12-trihydroxy eicosatrienoic acid and 10,11,12-trihydroxy eicosatrienoic acid
    • Pace-Asciak CR, Granström E and Samuelsson B: Arachidonic acid epoxides: Isolation and structure of 2 hydroxy epoxide intermediates in the formation of 8,11,12-trihydroxy eicosatrienoic acid and 10,11,12-trihydroxy eicosatrienoic acid. J Biol Chem 258: 6835-6840, 1983.
    • (1983) J. Biol. Chem. , vol.258 , pp. 6835-6840
    • Pace-Asciak, C.R.1    Granström, E.2    Samuelsson, B.3
  • 2
    • 0021250589 scopus 로고
    • Arachidonic acid epoxides. Demonstration through oxygen-18 labeled oxygen gas studies of an intramolecular transfer of the terminal hydroxyl group of 12S-hydroperoxy-eicosa-5,8,10,14-tetraenoic acid to form hydroxy epoxides
    • Pace-Asciak CR: Arachidonic acid epoxides. Demonstration through oxygen-18 labeled oxygen gas studies of an intramolecular transfer of the terminal hydroxyl group of 12S-hydroperoxy-eicosa-5,8,10,14-tetraenoic acid to form hydroxy epoxides. J Biol Chem 259: 8332-8337, 1984.
    • (1984) J. Biol. Chem. , vol.259 , pp. 8332-8337
    • Pace-Asciak, C.R.1
  • 3
    • 0021721480 scopus 로고
    • Hepoxilin, a new family of insulin secretagogues formed by intact rat pancreatic islets
    • Pace-Asciak CR and Martin JM: Hepoxilin, a new family of insulin secretagogues formed by intact rat pancreatic islets. Prostagl Leukotriene Med 16: 173-180, 1984.
    • (1984) Prostagl Leukotriene Med. , vol.16 , pp. 173-180
    • Pace-Asciak, C.R.1    Martin, J.M.2
  • 4
    • 0025195036 scopus 로고
    • Hepoxilin A3 induces changes in cytosolic calcium, intracellular pH and membrane potential in human neutrophils
    • Dho S, Grinstein S, Corey EJ, Su WG and Pace-Asciak CR: Hepoxilin A3 induces changes in cytosolic calcium, intracellular pH and membrane potential in human neutrophils. Biochem J 266: 63-68, 1990.
    • (1990) Biochem. J. , vol.266 , pp. 63-68
    • Dho, S.1    Grinstein, S.2    Corey, E.J.3    Su, W.G.4    Pace-Asciak, C.R.5
  • 5
    • 0027517490 scopus 로고
    • Hepoxilin A3 inhibits the rise in free intracellular calcium evoked by formyl-methionyl-leucyl-phenylalanine, platelet-activating factor and leukotriene B4
    • Laneuville O, Reynaud D, Grinstein S, Nigam S and Pace-Asciak CR: Hepoxilin A3 inhibits the rise in free intracellular calcium evoked by formyl-methionyl-leucyl-phenylalanine, platelet-activating factor and leukotriene B4. Biochem J 295: 393-397, 1993.
    • (1993) Biochem. J. , vol.295 , pp. 393-397
    • Laneuville, O.1    Reynaud, D.2    Grinstein, S.3    Nigam, S.4    Pace-Asciak, C.R.5
  • 6
    • 0020680952 scopus 로고
    • Resolution by DEAE cellulose chromatography of the enzymatic steps in the transformation of arachidonic acid into 8,11,12-trihydroxy eicosatrienoic acid and 10,11,12-trihydroxy eicosatrienoic acid by rat lung
    • Pace-Asciak CR, Mizuno K and Yamamoto S: Resolution by DEAE cellulose chromatography of the enzymatic steps in the transformation of arachidonic acid into 8,11,12-trihydroxy eicosatrienoic acid and 10,11,12-trihydroxy eicosatrienoic acid by rat lung. Prostaglandins 25 79-84, 1983.
    • (1983) Prostaglandins , vol.25 , pp. 79-84
    • Pace-Asciak, C.R.1    Mizuno, K.2    Yamamoto, S.3
  • 7
    • 0022568615 scopus 로고
    • Epoxide hydratase assay in human platelets using hepoxilin A3 as a lipid substrate
    • Pace-Asciak CR, Klein J and Spielberg SP: Epoxide hydratase assay in human platelets using hepoxilin A3 as a lipid substrate. Biochim Biophys Acta 875: 406-409, 1986.
    • (1986) Biochim. Biophys. Acta , vol.875 , pp. 406-409
    • Pace-Asciak, C.R.1    Klein, J.2    Spielberg, S.P.3
  • 8
    • 0024411066 scopus 로고
    • Purification of hepoxilin epoxide hydrolase from rat liver
    • Pace-Asciak CR and Lee W-S: Purification of hepoxilin epoxide hydrolase from rat liver. J Biol Chem 264: 9310-9313, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 9310-9313
    • Pace-Asciak, C.R.1    Lee, W.-S.2
  • 9
    • 0024343733 scopus 로고
    • New products in the hepoxilin pathway: Isolation of 11-glutathionyl hepoxilin A3 through reaction of hepoxilin A3 with glutathione S-transferase
    • Pace-Asciak CR, Laneuville O, Chang M, Reddy CC, Su W-G and Corey EJ: New products in the hepoxilin pathway: isolation of 11-glutathionyl hepoxilin A3 through reaction of hepoxilin A3 with glutathione S-transferase. Biochem Biophys Res Commun 163: 1230-1234, 1989.
    • (1989) Biochem. Biophys. Res. Commun. , vol.163 , pp. 1230-1234
    • Pace-Asciak, C.R.1    Laneuville, O.2    Chang, M.3    Reddy, C.C.4    Su, W.-G.5    Corey, E.J.6
  • 11
    • 0027315092 scopus 로고
    • Synthesis of racemic 11,12-cyclopropyl analogs of hepoxilins A3 and B3
    • Demin PM and Pace-Asciak CR: Synthesis of racemic 11,12-cyclopropyl analogs of hepoxilins A3 and B3. Tetrahedron Lett 34 4305-4308, 1993.
    • (1993) Tetrahedron. Lett. , vol.34 , pp. 4305-4308
    • Demin, P.M.1    Pace-Asciak, C.R.2
  • 13
    • 0344737009 scopus 로고    scopus 로고
    • The thromboxane receptor antagonist PBT-3, a hepoxilin stable analog, selectively antagonizes the TPa isoform in transfected COS-7 cells
    • Qiao N, Reynaud D, Demin P, Halushka PV and Pace-Asciak CR: The thromboxane receptor antagonist PBT-3, a hepoxilin stable analog, selectively antagonizes the TPa isoform in transfected COS-7 cells. J Pharm Exper Therap 307: 1142-1147, 2003.
    • (2003) J. Pharm. Exper. Therap. , vol.307 , pp. 1142-1147
    • Qiao, N.1    Reynaud, D.2    Demin, P.3    Halushka, P.V.4    Pace-Asciak, C.R.5
  • 14
    • 0036225172 scopus 로고    scopus 로고
    • A new family of thromboxane receptor antagonists with secondary thromboxane synthase inhibition
    • Pace-Asciak CR, Reynaud D, Demin P, Aslam R and Sun A: A new family of thromboxane receptor antagonists with secondary thromboxane synthase inhibition. J Pharm Exper Ther 301: 618-624, 2002.
    • (2002) J. Pharm. Exper. Ther. , vol.301 , pp. 618-624
    • Pace-Asciak, C.R.1    Reynaud, D.2    Demin, P.3    Aslam, R.4    Sun, A.5
  • 15
    • 0037181501 scopus 로고    scopus 로고
    • The hepoxilin analog PBT-3 inhibits heparin-activated platelet aggregation evoked by ADP
    • Reynaud D, Hinek A and Pace-Asciak CR: The hepoxilin analog PBT-3 inhibits heparin-activated platelet aggregation evoked by ADP. FEBS Lett 515: 58-60, 2002.
    • (2002) FEBS Lett. , vol.515 , pp. 58-60
    • Reynaud, D.1    Hinek, A.2    Pace-Asciak, C.R.3
  • 16
    • 1342345207 scopus 로고    scopus 로고
    • The hepoxilin stable analogue, PBT-3, inhibits primary, platelet-related hemostasis in whole blood measured in vitro with the PFA-100
    • Reynaud D, Clark D, Qiao N, Rand ML and Pace-Asciak CR: The hepoxilin stable analogue, PBT-3, inhibits primary, platelet-related hemostasis in whole blood measured in vitro with the PFA-100. Thromb Res 112: 245-248, 2003.
    • (2003) Thromb. Res. , vol.112 , pp. 245-248
    • Reynaud, D.1    Clark, D.2    Qiao, N.3    Rand, M.L.4    Pace-Asciak, C.R.5
  • 17
    • 0344442311 scopus 로고    scopus 로고
    • The hepoxilin analog PBT-3 induces apoptosis in BCR-ABL-positive K562 leukemia cells
    • Qiao N, Lam J, Reynaud D, Abdelhaleem M and Pace-Asciak CR: The hepoxilin analog PBT-3 induces apoptosis in BCR-ABL-positive K562 leukemia cells. Anticancer Res 23: 3617-3622, 2003.
    • (2003) Anticancer Res. , vol.23 , pp. 3617-3622
    • Qiao, N.1    Lam, J.2    Reynaud, D.3    Abdelhaleem, M.4    Pace-Asciak, C.R.5
  • 19
    • 1642575356 scopus 로고    scopus 로고
    • In vivo antitumor activity of a novel sulfonamide, HMN-214, against human tumor xenografts in mice and the spectrum of cytotoxicity of its active metabolite, HMN-176
    • Takagi M, Honmura T, Watanabe S, Yamaguchi R, Nogawa M, Nishimura I, Katoh F, Matsuda M and Hidaka H: In vivo antitumor activity of a novel sulfonamide, HMN-214, against human tumor xenografts in mice and the spectrum of cytotoxicity of its active metabolite, HMN-176. Invest New Drugs 21: 387-399, 2003.
    • (2003) Invest. New Drugs , vol.21 , pp. 387-399
    • Takagi, M.1    Honmura, T.2    Watanabe, S.3    Yamaguchi, R.4    Nogawa, M.5    Nishimura, I.6    Katoh, F.7    Matsuda, M.8    Hidaka, H.9
  • 20
    • 0033109530 scopus 로고    scopus 로고
    • Apoptotic cell death of human gastric tumor induced by nucleosides from CD57+HLA-DRbright natural suppressor cell line
    • Li X, Xu J, Guo M, Mori E and Mori T: Apoptotic cell death of human gastric tumor induced by nucleosides from CD57+HLA-DRbright natural suppressor cell line. Int J Oncol 14: 687-694, 1999.
    • (1999) Int. J. Oncol. , vol.14 , pp. 687-694
    • Li, X.1    Xu, J.2    Guo, M.3    Mori, E.4    Mori, T.5
  • 21
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
    • Kaufmann SH: Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res 49: 5870-5878, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 24
    • 0034652007 scopus 로고    scopus 로고
    • Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na(+)/H(+) exchanger
    • Rich IN, Worthington-White D, Garden OA and Musk P: Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na(+)/H(+) exchanger. Blood 15: 1427-1434, 2000.
    • (2000) Blood , vol.15 , pp. 1427-1434
    • Rich, I.N.1    Worthington-White, D.2    Garden, O.A.3    Musk, P.4
  • 25
    • 0034673334 scopus 로고    scopus 로고
    • Activation of caspase-3 in molt4 cells by apoptosis-inducing nucleosides from CD57(+)HLA-DR(bright) natural suppressor cell line
    • Li X, Guo M, Mori E and Mori T: Activation of caspase-3 in molt4 cells by apoptosis-inducing nucleosides from CD57(+)HLA-DR(bright) natural suppressor cell line. Biochem Biophys Res Commun 268: 514-520, 2000.
    • (2000) Biochem. Biophys. Res. Commun. , vol.268 , pp. 514-520
    • Li, X.1    Guo, M.2    Mori, E.3    Mori, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.