Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: Molecular mechanisms of a tumor suppressor

Journal of Biological Chemistry

Volumn 286, Issue 19, 2011, Pages 17270-17280

  Waters, Lorna C ^a   Strong, Sarah L ^a   Ferlemann, Eva ^b   Oka, Ojore ^a   Muskett, Frederick W ^a   Veverka, Vaclav ^a   Banerjee, Sreemoti ^a   Schmedt, Thore ^b   Henry, Alistair J ^c   Klempnauer, Karl Heinz ^b   Carr, Mark D ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UCB PHARMA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX FORMATIONS; DIRECT INTERACTIONS; IN-VIVO; INTER-DOMAIN; MOLECULAR MECHANISM; NMR STUDIES; PHYSIOLOGICAL CONDITION; RNA HELICASES; SALT BRIDGES; SINGLE MOLECULE; TUMOR SUPPRESSOR PROTEINS; TUMOR SUPPRESSORS; TWO DOMAINS;

HYDROGEN BONDS; RNA; STOICHIOMETRY;

TUMORS;

PROGRAMMED CELL DEATH PROTEIN 4; PROTEIN ELF4A; PROTEIN ELF4G; RNA HELICASE; SODIUM CHLORIDE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; HYDROGEN BOND; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; EUKARYOTIC INITIATION FACTOR-4A; EUKARYOTIC INITIATION FACTOR-4G; GENE EXPRESSION REGULATION; GENES, TUMOR SUPPRESSOR; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PLASMIDS; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; RNA-BINDING PROTEINS;

EID: 79955763330     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.166157     Document Type: Article

References (53)

1. Shibahara, K., Asano, M., Ishida, Y., Aoki, T., Koike, T., and Honjo, T. (1995) Gene 166, 297-301
2. Cmarik, J. L., Min, H., Hegamyer, G., Zhan, S., Kulesz-Martin, M., Yoshinaga, H., Matsuhashi, S., and Colburn, N. H. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 14037-14042
3. Jansen, A. P., Camalier, C. E., and Colburn, N. H. (2005) Cancer Res. 65, 6034-6041
4. Hilliard, A., Hilliard, B., Zheng, S. J., Sun, H., Miwa, T., Song, W., Göke, R., and Chen, Y. H. (2006) J. Immunol. 177, 8095-8102
5. Afonja, O., Juste, D., Das, S., Matsuhashi, S., and Samuels, H. H. (2004) Oncogene 23, 8135-8145
6. Chen, Y., Knösel, T., Kristiansen, G., Pietas, A., Garber, M. E., Matsuhashi, S., Ozaki, I., and Petersen, I. (2003) J. Pathol. 200, 640-646
7. Wang, Q., Sun, Z., and Yang, H. S. (2008) Oncogene 27, 1527-1535
8. Wang, X., Wei, Z., Gao, F., Zhang, X., Zhou, C., Zhu, F., Wang, Q., Gao, Q., Ma, C., Sun, W., Kong, B., and Zhang, L. (2008) Anticancer Res. 28, 2991-2996
9. Zhang, H., Ozaki, I., Mizuta, T., Hamajima, H., Yasutake, T., Eguchi, Y., Ideguchi, H., Yamamoto, K., and Matsuhashi, S. (2006) Oncogene 25, 6101-6112
10. Jansen, A. P., Camalier, C. E., Stark, C., and Colburn, N. H. (2004) Mol. Cancer Ther. 3, 103-110
11. Mudduluru, G., Medved, F., Grobholz, R., Jost, C., Gruber, A., Leupold, J. H., Post, S., Jansen, A., Colburn, N. H., and Allgayer, H. (2007) Cancer 110, 1697-1707
12. Bitomsky, N., Wethkamp, N., Marikkannu, R., and Klempnauer, K. H. (2008) Oncogene 27, 4820-4829
13. Singh, P., Marikkannu, R., Bitomsky, N., and Klempnauer, K. H. (2009) Oncogene 28, 3758-3764
14. Yang, H. S., Jansen, A. P., Komar, A. A., Zheng, X., Merrick, W. C., Costes, S., Lockett, S. J., Sonenberg, N., and Colburn, N. H. (2003) Mol. Cell. Biol. 23, 26-37
15. Yang, H. S., Cho, M. H., Zakowicz, H., Hegamyer, G., Sonenberg, N., and Colburn, N. H. (2004) Mol. Cell. Biol. 24, 3894-3906
16. Bitomsky, N., Böhm, M., and Klempnauer, K. H. (2004) Oncogene 23, 7484-7493
17. Wedeken, L., Ohnheiser, J., Hirschi, B., Wethkamp, N., and Klempnauer, K. H. (2010) Genes and Cancer 1, 293-301
18. Böhm, M., Sawicka, K., Siebrasse, J. P., Brehmer-Fastnacht, A., Peters, R., and Klempnauer, K. H. (2003) Oncogene 22, 4905-4910
19. Lankat-Buttgereit, B., and Göke, R. (2009) Biol. Cell 101, 309-317
20. Waters, L. C., Veverka, V., Böhm, M., Schmedt, T., Choong, P. T., Muskett, F. W., Klempnauer, K. H., and Carr, M. D. (2007) Oncogene 26, 4941-4950
21. Loh, P. G., Yang, H. S., Walsh, M. A., Wang, Q., Wang, X., Cheng, Z., Liu, D., and Song, H. (2009) EMBO J. 28, 274-285
22. Suzuki, C., Garces, R. G., Edmonds, K. A., Hiller, S., Hyberts, S. G., Marintchev, A., and Wagner, G. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 3274-3279
23. Ponting, C. P. (2000) Trends Biochem. Sci. 25, 423-426
24. Marintchev, A., and Wagner, G. (2004) Q. Rev. Biophys. 37, 197-284
25. Pestova, T. V., Lorsch, J. R., and Hellen, C. U. T. (2007) in Translational Control in Biology and Medicine (Mathews, M. B., Sonenberg, N., and Hershey, J. W. B., eds) pp 87-128, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
26. Abramson, R. D., Dever, T. E., Lawson, T. G., Ray, B. K., Thach, R. E., and Merrick, W. C. (1987) J. Biol. Chem. 262, 3826-3832
27. Richter-Cook, N. J., Dever, T. E., Hensold, J. O., and Merrick, W. C. (1998) J. Biol. Chem. 273, 7579-7587
28. Rogers, G. W., Jr., Richter, N. J., Lima, W. F., and Merrick, W. C. (2001) J. Biol. Chem. 276, 30914-30922
29. Rozen, F., Edery, I., Meerovitch, K., Dever, T. E., Merrick, W. C., and Sonenberg, N. (1990) Mol. Cell. Biol. 10, 1134-1144
30. Marcotrigiano, J., Lomakin, I. B., Sonenberg, N., Pestova, T. V., Hellen, C. U., and Burley, S. K. (2001) Mol. Cell 7, 193-203
31. Lamphear, B. J., Kirchweger, R., Skern, T., and Rhoads, R. E. (1995) J. Biol. Chem. 270, 21975-21983
32. Morino, S., Imataka, H., Svitkin, Y. V., Pestova, T. V., and Sonenberg, N. (2000) Mol. Cell. Biol. 20, 468-477
33. Imataka, H., and Sonenberg, N. (1997) Mol. Cell. Biol. 17, 6940-6947
34. De Gregorio, E., Preiss, T., and Hentze, M. W. (1999) EMBO J. 18, 4865-4874
35. Marintchev, A., Edmonds, K. A., Marintcheva, B., Hendrickson, E., Oberer, M., Suzuki, C., Herdy, B., Sonenberg, N., and Wagner, G. (2009) Cell 136, 447-460
36. Oberer, M., Marintchev, A., and Wagner, G. (2005) Genes Dev. 19, 2212-2223
37. Schütz, P., Bumann, M., Oberholzer, A. E., Bieniossek, C., Trachsel, H., Altmann, M., and Baumann, U. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 9564-9569
38. LaRonde-LeBlanc, N., Santhanam, A. N., Baker, A. R., Wlodawer, A., and Colburn, N. H. (2007) Mol. Cell. Biol. 27, 147-156
39. Kang, M. J., Ahn, H. S., Lee, J. Y., Matsuhashi, S., and Park, W. Y. (2002) Biochem. Biophys. Res. Commun. 293, 617-621
40. Chang, J. H., Cho, Y. H., Sohn, S. Y., Choi, J. M., Kim, A., Kim, Y. C., Jang, S. K., and Cho, Y. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 3148-3153
41. Waters, L. C., Böhm, M., Veverka, V., Muskett, F. W., Frenkiel, T. A., Kelly, G. P., Prescott, A., Dosanjh, N. S., Klempnauer, K. H., and Carr, M. D. (2006) J. Biomol. NMR 36, 18-18
42. Waters, L. C., Oka, O., Muskett, F. W., Strong, S. L., Schmedt, T., Klempnauer, K. H., and Carr, M. D. (2010) Biomol. NMR Assign. 4, 49-53
43. Waters, L., Yue, B., Veverka, V., Renshaw, P., Bramham, J., Matsuda, S., Frenkiel, T., Kelly, G., Muskett, F., Carr, M., and Heery, D. M. (2006) J. Biol. Chem. 281, 14787-14795
44. Renshaw, P. S., Panagiotidou, P., Whelan, A., Gordon, S. V., Hewinson, R. G., Williamson, R. A., and Carr, M. D. (2002) J. Biol. Chem. 277, 21598-21603
45. Boozer, C., Kim, G., Cong, S., Guan, H., and Londergan, T. (2006) Curr. Opin. Biotechnol. 17, 400-405
46. Homola, J. (2008) Chem. Rev. 108, 462-493
47. Dominguez, C., Boelens, R., and Bonvin, A. M. (2003) J. Am. Chem. Soc. 125, 1731-1737
48. Cornilescu, G., Delaglio, F., and Bax, A. (1999) J. Biomol. NMR 13, 289-302
49. Rothbauer, U., Zolghadr, K., Muyldermans, S., Schepers, A., Cardoso, M. C., and Leonhardt, H. (2008) Mol. Cell. Proteomics 7, 282-289
50. Pause, A., Méthot, N., Svitkin, Y., Merrick, W. C., and Sonenberg, N. (1994) EMBO J. 13, 1205-1215
51. Korneeva, N. L., Lamphear, B. J., Hennigan, F. L., Merrick, W. C., and Rhoads, R. E. (2001) J. Biol. Chem. 276, 2872-2879
52. Li, W., Belsham, G. J., and Proud, C. G. (2001) J. Biol. Chem. 276, 29111-29115
53. Nielsen, K. H., Behrens, M. A., He, Y., Oliveira, C. L., Sottrup Jensen, L., Hoffmann, S. V., Pedersen, J. S., and Andersen, G. R. (2011) Nucleic Acids Res., in press