Effect of Linoleic acid of Nigella sativa on MDA-MB-231 human breast cancer cells

Iranian Journal of Cancer Prevention

Volumn 4, Issue 2, 2011, Pages 65-70

  Hasanzadeh, G K ^a   Latiffah, A L ^a   Hanachi, P ^b   Hj Lajis, N ^c  

^a University Putra   (Malaysia)

^b ALZAHRA UNIVERSITY   (Iran)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Linoleic acid; MDA MB 231; Nigella sativa

Indexed keywords

LINOLEIC ACID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLACK CUMIN; BREAST CANCER; CANCER INHIBITION; CELL CYCLE PHASE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50;

NIGELLA SATIVA;

EID: 79955756357     PISSN: None     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Lim GCC. Cancer in Malaysia- There is light at the end of the Tunnel. Medical Journal of Malaysia 2003; 58(5): 632-5.
2. Kong JM, Goh NK, Chia LS, Chia TF. Recent advances in traditional plant drugs and orchids. Acta Pharmacol Sin.2003; 24: 7-21.
3. Narayanan BA, Simi B, Reddy BS. Modulation of inducible nitric oxide syntheses and related pro inflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells, Cancer Res. 2003; 63: 972-9.
4. Calder PC. N-3 polyunsaturated fatty acids and inflammation: from molecular biology to the clinic, Lipids. 2003; 38: 343-52.
5. Hirayama T. Epidemiology of breast cancer with special reference to the role of diet, Orev. Med. 1978; 7: 173-95.
6. Wynder EL, Rose DP, Cohen LA. Diet and breast cancer in causation and therapy, Cancer. 1986; 58: 1804-13.
7. Chujo H, Yamasaki M, Nou S, Koyanagi N, Tachibana H, Yamada K. Effect of conjugated linoleic acid isomers on growth factor-induced proliferation of human breast cancer cells, Cancer Letter. 2003; 202: 81-7.
8. Tanmahasamut P, Liu J, Hendry LB, Sidell N. Conjugated linoleic Acid blocks estrogen signaling in human breast cancer cells, J. Nutr. 2004; 134: 674-80.
9. Kim EJ, Kang IJ, Cho HJ, Kim WK, Ha YL, Park JH. Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells,J. Nutr. 2003; 133: 2675-81.
10. Ochoa JJ, Farquharson AJ, Grant I, Moffat LE, Heys SD, Wahle KW. Conjugated linoleic acids (CLA's) decrease prostate cancer cell proliferation: different molecular mechanisms for cis-9, trans-11 and trans-10, cis-12 isomers, Carcinogenesis. 2004; 25: 1185-91.
11. Miglietta, A, Bozzo F, Bocca C, Gabriel L, Trombetta A, Belotti S, Canuto RA. Conjugated linoleic acid induces apoptosis in MDA-MB-231breast cancer cells through ERK/MAPK signaling and mitochondrial pathway, Cancer Letters. 2006; 234: 149-57.
12. Chamras H, Ardashian A, Heber D, Glaspy JA. Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation, Journal of Nutritional Biochemistry. 2002; 13: 711-6.
13. Kim JH, Hubbarda NE, Ziboh V, Erickson KL. Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein, Biochimica et Biophysica Acta. 2005; 1736:244 -50.
14. Ip C, CA Carter, MM Ip. Requirement of essential fatty acid for mammary tumorigenesis in the rat, Cancer Res. 1985; 45:1997-2001.
15. Belury MA, Nickel KP, Bird CE, Wu Y. Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion, Nutr. Cancer. 1996; 26:149-57.
16. Shultz TD, Chew BP, Seaman WR. Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture, Anticancer Res. 1992; 12: 2143-5.
17. Park Y, Allen KG, Shultz TD. Modulation of MCF-7 breast cancer cell signal transduction by linoleic acid and conjugated linoleic acid in culture, Anticancer Res. 2000; 20: 669-76.
18. Reed-Muench H. A simple method of estimating fifty percent endpoints. The American Journal of Hygiene. 1938; 27: 493-7.
19. Ormerod MG. Flow Cytometry A Practical Approach, Second Ed. Oxford University Press, Inc. 1992, New York, NY, USA.
20. Norsharina I, Latiffah AL, Maznah I, Musalmah M, Hanacchi P. Neuroprotective effect of Black Seeds (Nigella sativa) on amyloid β peptide (Aβ) - induced cell lines. Supplement, Iranian Journal Pharmaceutical Sciences. 2006; 2(3): 241.
21. Abdulelah HAA, Zainal-Abidin BAH. In Vivo anti-malarial tests of Nigella sativa (Black Seed) different extracts. American Journal of Pharmacology and Toxicology.2007; 2(2): 46-50.
22. Maria FC, Celine P, Rui C. Comparative toxicity of oleic acid and linoleic acid on Jurkat cells. J. Clinical Nutrition 2004; 23(4): 721-32.
23. Thais MD, Maria FC, Gisele G, Maria TN, Rui C. Comparative toxicity of fatty acids on a macrophage cell line (J774). Clinical Science, 2006; 111: 307-17.
24. Maria FC, Celine P, Rui, C. Comparative toxicity of oleic acid and linoleic acid on Raji cells. J. Nutrition. 2005; 21(3):395-405.
25. Clement IP, Margot MI, Tamora L, Suzanne S, Wendy S. Induction of Apoptosis by Conjugated Linoleic Acid in Cultured Mammary Tumor Cells and PremalignantLesions of the Rat Mammary Gland. Cancer Epidemiology, J. Biomarkers & Prevention 2000; 9: 689-96.
26. Jess LM, Chris CA, Merlyn KN, Xiaoli C, Clifton AB. Conjugated Linoleic Acid (CLA), Body Fat, and Apoptosis. Obesity Research 2001; 9: 129-34.
27. Paolo B, Diomira L, Mauro R. Conjugated Linoleic Acid - Mediated Apoptosis in Jurkat T Cells Involves the Production of Reactive Oxygen Species. Cell Physiology and Biochemistry. 2004; 14: 57-64.
28. Li-Shu W, Yi-Wen H, Suling L, Pearlly Y, Young CL. Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. BMC Cancer. 2008; 8: 208-12.
29. Andrade LN, de Lima TM, Curl R, Castrucci AM. Toxicity of fatty acids on murine and human melanoma cell lines. Toxicology In vitro. 2005; 19: 553-660.
30. Chamras H, Ardashian A, Heber D, Glaspy JA. Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation, Journal of Nutritional Biochemistry. 2002; 13: 711-6.
31. Belury MA. Inhibition of carcinogenesis by conjugated linoleic acid: potential mechanisms of action, J. Nutr. 2002; 132:2995-8.
32. Thompson H, Zhu Z, Banni S, Darcy K, Loftus TV, Ip C. Morphological and biochemical status of the mammary gland as influenced by conjugated linoleic acid: implication for a reduction in mammary cancer risk, Cancer Res. 1997; 57: 5067-72.
33. Ip C, Chin SF, Scimeca JA, Pariza MW: Mammary cancer prevention by conjugated dienoic derivative of linoleic acid. Cancer Res.1991; 51: 6118-24, 1991.
34. Ip C, Dong Y, Ip MM, Banni S, Carta G, Angioni E, Murru E, Spada S, Melis MP, Saebo A. Conjugated linoleic acid isomers and mammary cancer prevention, Nutr. Cancer. 2002; 43(1): 52-8.
35. Liew C, Schut H AJ, Chin SF, Pariza MW, Dashwood RH. Protection of conjugated linoleic acid against 2-amino-3-methylimidazol [4, 5-f] quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms, Carcinogenesis. 1995; 16: 3037-43.
36. Belury MA, Nickel KP, Bird CE, Wu Y. Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion, Nutr. Cancer. 1996; 26(2): 149-57.
37. Kavanaugh CJ, Liu KL, Belury MA. Effect of dietary conjugated linoleic acid on phorbol ester-induced PGE2 production and hyperplasia in mouse epidermis, Nutr. Cancer. 1999; 33: 132-8.