SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts

Physiological Genomics

Volumn 43, Issue 7, 2011, Pages 357-364

  Wang, Hong Sheng ^a   Arvanitis, Demetrios A ^b   Dong, Min ^a   Niklewski, Paul J ^a   Zhao, Wen ^a   Lam, Chi Keung ^a   Kranias, Evangelia G ^a,b   Sanoudou, Despina ^b,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ATHENS   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Ca2+ cycling; Electrophysiology; Genomics; Hypertrophy; Microarrays

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; KCND2 PROTEIN; PHOSPHOLAMBAN; POTASSIUM CHANNEL; POTASSIUM ION; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2A; SHAL POTASSIUM CHANNEL; SLC8A1 PROTEIN; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CHANNEL NAV1.7; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION PROFILING; HEART ELECTROPHYSIOLOGY; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HEART VENTRICLE REMODELING; HOMEOSTASIS; MALE; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; COMPUTATIONAL BIOLOGY; ELECTROPHYSIOLOGY; HUMANS; IMMUNOBLOTTING; MALE; MICE; MODELS, THEORETICAL; MYOCYTES, CARDIAC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES;

MAMMALIA; MUS; MUS MUSCULUS;

EID: 79955754967     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00032.2010     Document Type: Article

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