메뉴 건너뛰기




Volumn 10, Issue 3, 2011, Pages 505-517

Connexin-26 is a key factor mediating gemcitabine bystander effect

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 26; CONNEXIN 32; CONNEXIN 36; CONNEXIN 43; GEMCITABINE; MESSENGER RNA;

EID: 79955751723     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-10-0693     Document Type: Article
Times cited : (34)

References (37)
  • 2
  • 4
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine
    • Heinemann V, Hertel LW, Grindey GB, Plunkett W. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′- difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine. Cancer Res 1988;48:4024-31.
    • (1988) Cancer Res , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 5
    • 0037192631 scopus 로고    scopus 로고
    • Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: Critical role of DNA breaks, Bcl-2 decline and caspase-9 activation
    • DOI 10.1038/sj.onc.1205280
    • Tomicic MT, Thust R, Kaina B. Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, Bcl-2 decline and caspase-9 activation. Oncogene 2002;21:2141-53. (Pubitemid 34311368)
    • (2002) Oncogene , vol.21 , Issue.14 , pp. 2141-2153
    • Tomicic, M.T.1    Thust, R.2    Kaina, B.3
  • 6
    • 0037832252 scopus 로고    scopus 로고
    • Suicide gene therapy-mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: Fifteen years of application
    • Fillat C, Carrio M,Cascante A,Sangro B. Suicide gene therapy-mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application. Curr Gene Ther 2003;3:13-26.
    • (2003) Curr Gene Ther , vol.3 , pp. 13-26
    • Fillat, C.1    Carrio, M.2    Cascante, A.3    Sangro, B.4
  • 7
    • 0035479932 scopus 로고    scopus 로고
    • Retrovirus-mediated transfer of the herpes simplex virus thymidine kinase and connexin26 genes in pancreatic cells results in variable efficiency on the bystander killing: Implications for gene therapy
    • DOI 10.1002/ijc.1429
    • Carrio M, Mazo A, Lopez-Iglesias C, Estivill X, Fillat C. Retrovirus-mediated transfer of the herpes simplex virus thymidine kinase and connexin26 genes in pancreatic cells results in variable efficiency on the bystander killing: implications for gene therapy. Int J Cancer 2001;94:81-8. (Pubitemid 32801756)
    • (2001) International Journal of Cancer , vol.94 , Issue.1 , pp. 81-88
    • Carri, M.1    Mazo, A.2    Lpez-Iglesias, C.3    Estivill, X.4    Fillat, C.5
  • 8
    • 33646078796 scopus 로고    scopus 로고
    • Connexin over-expression differentially suppresses glioma growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy
    • Jimenez T, Fox WP, Naus CC, Galipeau J, Belliveau DJ. Connexin over-expression differentially suppresses glioma growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy. Cell Commun Adhes 2006;13:79-92.
    • (2006) Cell Commun Adhes , vol.13 , pp. 79-92
    • Jimenez, T.1    Fox, W.P.2    Naus, C.C.3    Galipeau, J.4    Belliveau, D.J.5
  • 10
    • 77953246221 scopus 로고    scopus 로고
    • Gemcitabine intercellular diffusion mediated by gap junctions: New implications for cancer therapy
    • Cottin S, Ghani K, de Campos-Lima PO, Caruso M. Gemcitabine intercellular diffusion mediated by gap junctions: new implications for cancer therapy. Mol Cancer;9:141.
    • Mol Cancer , vol.9 , pp. 141
    • Cottin, S.1    Ghani, K.2    De Campos-Lima, P.O.3    Caruso, M.4
  • 11
    • 0030028301 scopus 로고    scopus 로고
    • The gap junction communication channel
    • DOI 10.1016/S0092-8674(00)81282-9
    • Kumar NM, Gilula NB. The gap junction communication channel. Cell 1996;84:381-8. (Pubitemid 26060720)
    • (1996) Cell , vol.84 , Issue.3 , pp. 381-388
    • Kumar, N.M.1    Gilula, N.B.2
  • 13
    • 42949151882 scopus 로고    scopus 로고
    • Aberrant expression and localization of connexin43 and connexin30 in a rat glioma cell line
    • DOI 10.1002/mc.20393
    • Mennecier G, Derangeon M, Coronas V, Herve JC, Mesnil M. Aberrant expression and localization of connexin43 and connexin30 in a rat glioma cell line. Mol Carcinog 2008;47:391-401. (Pubitemid 351614579)
    • (2008) Molecular Carcinogenesis , vol.47 , Issue.5 , pp. 391-401
    • Mennecier, G.1    Derangeon, M.2    Coronas, V.3    Herve, J.-C.4    Mesnil, M.5
  • 14
    • 28944441155 scopus 로고    scopus 로고
    • Defective gap junctional intercellular communication in the carcinogenic process
    • DOI 10.1016/j.bbamem.2005.11.004, PII S0005273605003615, The Connexins Part III
    • Mesnil M, Crespin S, Avanzo JL, Zaidan-Dagli ML. Defective gap junctional intercellular communication in the carcinogenic process. Biochim Biophys Acta 2005;1719:125-45. (Pubitemid 41785641)
    • (2005) Biochimica et Biophysica Acta - Biomembranes , vol.1719 , Issue.1-2 , pp. 125-145
    • Mesnil, M.1    Crespin, S.2    Avanzo, J.-L.3    Zaidan-Dagli, M.-L.4
  • 16
    • 33845733149 scopus 로고    scopus 로고
    • Targeting the CYP2B1/cyclophosphamide suicide system to fibroblast growth factor receptors results in a potent antitumoral response in pancreatic cancer models
    • DOI 10.1089/hum.2006.17.1187
    • Huch M, Abate-Daga D, Roig JM, González JR, Fabregat J, Sosnowski B, et al. Targeting the CYP2B 1/cyclophosphamide suicide system to fibroblast growth factor receptors results in a potent antitumoral response in pancreatic cancer models. Hum Gene Ther 2006;17:1187-200. (Pubitemid 44975136)
    • (2006) Human Gene Therapy , vol.17 , Issue.12 , pp. 1187-1200
    • Huch, M.1    Abate-Daga, D.2    Roig, J.M.3    Gonzalez, J.R.4    Fabregat, J.5    Sosnowski, B.6    Mazo, A.7    Fillat, C.8
  • 17
    • 0031847421 scopus 로고    scopus 로고
    • Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma
    • Liu N, Furukawa T, Kobari M, Tsao MS. Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma. Am J Pathol 1998;153:263-9. (Pubitemid 28317529)
    • (1998) American Journal of Pathology , vol.153 , Issue.1 , pp. 263-269
    • Liu, N.1    Furukawa, T.2    Kobari, M.3    Tsao, M.-S.4
  • 19
    • 4043150786 scopus 로고    scopus 로고
    • Breast cancer metastatic potential: Correlation with increased heterotypic gap junctional intercellular communication between breast cancer cells and osteoblastic cells
    • DOI 10.1002/ijc.20318
    • Kapoor P, Saunders MM, Li Z, Zhou Z, Sheaffer N, Kunze EL, et al. Breast cancer metastatic potential: correlation with increased heterotypic gap junctional intercellular communication between breast cancer cells and osteoblastic cells. Int J Cancer 2004;111:693-7. (Pubitemid 39062890)
    • (2004) International Journal of Cancer , vol.111 , Issue.5 , pp. 693-697
    • Kapoor, P.1    Saunders, M.M.2    Li, Z.3    Zhou, Z.4    Sheaffer, N.5    Kunze, E.L.6    Samant, R.S.7    Welch, D.R.8    Donahue, H.J.9
  • 20
    • 0027142023 scopus 로고
    • Statistical analysis of in vivo tumor growth experiments
    • Heitjan DF, Manni A, Santen RJ. Statistical analysis of in vivo tumor growth experiments. Cancer Res 1993;53:6042-50. (Pubitemid 24006181)
    • (1993) Cancer Research , vol.53 , Issue.24 , pp. 6042-6050
    • Heitjan, D.F.1    Manni, A.2    Santen, R.J.3
  • 22
    • 23844469160 scopus 로고    scopus 로고
    • Enhancement of gemcitabine-induced apoptosis by restoration of p53 function in human pancreatic tumors
    • DOI 10.1159/000086772
    • Cascallo M, Calbo J, Capella G, Fillat C, Pastor-Anglada M, Mazo A. Enhancement of gemcitabine-induced apoptosis by restoration of p53 function in human pancreatic tumors. Oncology 2005;68:179-89. (Pubitemid 41158974)
    • (2005) Oncology , vol.68 , Issue.2-3 , pp. 179-189
    • Cascallo, M.1    Calbo, J.2    Capella, G.3    Filiat, C.4    Pastor-Anglada, M.5    Mazo, A.6
  • 24
    • 46649083576 scopus 로고    scopus 로고
    • Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer
    • Pérez-Torras S, García-Manteiga J, Mercadé E, Casado FJ, Carbó N, Pastor-Anglada M, et al. Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer. Biochem Pharmacol 2008;76:322-9.
    • (2008) Biochem Pharmacol , vol.76 , pp. 322-329
    • Pérez-Torras, S.1    García-Manteiga, J.2    Mercadé, E.3    Casado, F.J.4    Carbó, N.5    Pastor-Anglada, M.6
  • 26
    • 33644991492 scopus 로고    scopus 로고
    • Increased expression of connexin 26 in the invasive component of lung squamous cell carcinoma: Significant correlation with poor prognosis
    • Ito A, Koma Y, Uchino K, Okada T, Ohbayashi C, Tsubota N, et al. Increased expression of connexin 26 in the invasive component of lung squamous cell carcinoma: significant correlation with poor prognosis. Cancer Lett 2006;234:239-48.
    • (2006) Cancer Lett , vol.234 , pp. 239-248
    • Ito, A.1    Koma, Y.2    Uchino, K.3    Okada, T.4    Ohbayashi, C.5    Tsubota, N.6
  • 27
    • 34848858289 scopus 로고    scopus 로고
    • Connexin26 expression is associated with lymphatic vessel invasion and poor prognosis in human breast cancer
    • DOI 10.1007/s10549-006-9465-8
    • Naoi Y, Miyoshi Y, Taguchi T, Kim SJ, Arai T, Tamaki Y, et al. Connexin26 expression is associated with lymphatic vessel invasion and poor prognosis in human breast cancer. Breast Cancer Res Treat 2007;106:11-7. (Pubitemid 47498083)
    • (2007) Breast Cancer Research and Treatment , vol.106 , Issue.1 , pp. 11-17
    • Naoi, Y.1    Miyoshi, Y.2    Taguchi, T.3    Kim, S.J.4    Arai, T.5    Tamaki, Y.6    Noguchi, S.7
  • 28
    • 34247570915 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor correlates with connexin 26 and Bcl-xL expression in human colorectal cancer
    • DOI 10.1196/annals.1378.029, Signal Transduction Pathways, Part A: Apoptotic and Extracellular Signalling
    • Sulkowski S, Kanczuga-Koda L, Koda M, Wincewicz A, Sulkowska M. Insulin-like growth factor-I receptor correlates with connexin 26 and Bcl-xL expression in human colorectal cancer. Ann N Y Acad Sci 2006;1090:265-75. (Pubitemid 47092131)
    • (2006) Annals of the New York Academy of Sciences , vol.1090 , pp. 265-275
    • Sulkowski, S.1    Kanczuga-Koda, L.2    Koda, M.3    Wincewicz, A.4    Sulkowska, M.5
  • 30
    • 56049092037 scopus 로고    scopus 로고
    • Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43
    • Cottin S, Ghani K, Caruso M. Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43. Cancer Gene Ther 2008;15:823-31.
    • (2008) Cancer Gene Ther , vol.15 , pp. 823-831
    • Cottin, S.1    Ghani, K.2    Caruso, M.3
  • 32
    • 18844362687 scopus 로고    scopus 로고
    • Connexin26 is responsible for anionic molecule permeability in the cochlea for intercellular signalling and metabolic communications
    • Zhao HB. Connexin26 is responsible for anionic molecule permeability in the cochlea for intercellular signalling and metabolic communications. Eur J Neurosci 2005;21:1859-68.
    • (2005) Eur J Neurosci , vol.21 , pp. 1859-1868
    • Zhao, H.B.1
  • 33
    • 63849141447 scopus 로고    scopus 로고
    • Structure of the connexin 26 gap junction channel at 3.5 A resolution
    • Maeda S, Nakagawa S, Suga M, Yamashita E, Oshima A, Fujiyoshi Y, et al. Structure of the connexin 26 gap junction channel at 3.5 A resolution. Nature 2009;458:597-602.
    • (2009) Nature , vol.458 , pp. 597-602
    • Maeda, S.1    Nakagawa, S.2    Suga, M.3    Yamashita, E.4    Oshima, A.5    Fujiyoshi, Y.6
  • 34
    • 77955980879 scopus 로고    scopus 로고
    • Structural and functional studies of gap junction channels
    • Nakagawa S, Maeda S, Tsukihara T. Structural and functional studies of gap junction channels. Curr Opin Struct Biol 2010;20:423-30.
    • (2010) Curr Opin Struct Biol , vol.20 , pp. 423-430
    • Nakagawa, S.1    Maeda, S.2    Tsukihara, T.3
  • 35
    • 0037184068 scopus 로고    scopus 로고
    • Gap junctions between cells expressing connexin 43 or 32 show inverse permselectivity to adenosine and ATP
    • Goldberg GS, Moreno AP, Lampe PD. Gap junctions between cells expressing connexin 43 or 32 show inverse permselectivity to adenosine and ATP. J Biol Chem 2002;277:36725-30.
    • (2002) J Biol Chem , vol.277 , pp. 36725-36730
    • Goldberg, G.S.1    Moreno, A.P.2    Lampe, P.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.