Epinephrine auto-injector use in adolescents at risk of anaphylaxis: A qualitative study in Scotland, UK

Clinical and Experimental Allergy

Volumn 41, Issue 6, 2011, Pages 869-877

  Gallagher, M ^a   Worth, A ^a   Cunningham Burley, S ^a   Sheikh, A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Adolescent health; Adrenaline; Anaphylaxis; Auto injector; Epinephrine; Patient education

Indexed keywords

ADRENALIN;

ADOLESCENT; ADOLESCENT HEALTH; ADULT; ANAPHYLAXIS; ARTICLE; ATTITUDE TO HEALTH; AUTO INJECTOR; AUTOMATION; DEVICE; EMERGENCY TREATMENT; FEMALE; FOOD ALLERGY; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL SPECIALIST; MILK ALLERGY; NURSE; OUTCOME OF EDUCATION; PARENTAL ATTITUDE; PATIENT COMPLIANCE; PATIENT EDUCATION; PEANUT ALLERGY; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; QUALITATIVE RESEARCH; SELF INJECTION; TRAINING; TREATMENT INDICATION; UNITED KINGDOM;

ADOLESCENT; ADRENERGIC AGONISTS; ADULT; ANAPHYLAXIS; EPINEPHRINE; FEMALE; HUMANS; INJECTIONS, INTRAMUSCULAR; INTERVIEWS AS TOPIC; MALE; QUALITATIVE RESEARCH; SCOTLAND; SELF MEDICATION; YOUNG ADULT;

EID: 79955748815     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03743.x     Document Type: Article

References (38)

1. Pumphrey RSH. Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy 2000; 30:1144-50.
2. Bock SA, Munoz-Furlong A, Sampson HA. Fatalities due to anaphylactic reactions to food. J Allergy Clin Immunol 2001; 107:191-3.
3. Uguz A, Lack G, Pumphrey R et al. Allergic reactions in the community: a questionnaire survey of members of the anaphylaxis campaign. Clin Exp Allergy 2005; 35:746-50.
4. Sampson HA, Munoz-Furlong A, Sicherer SH. Risk-taking and coping strategies of adolescents and young adults with food allergy. J Allergy Clin Immunol 2006; 117:1440-5.
5. Akeson N, Worth A, Sheikh A. The psychosocial impact of anaphylaxis on young people and their parents. Clin Exp Allergy 2007; 37:1213-20.
6. Bock SA, Munoz-Furlong A, Sampson HA. Further fatalities caused by anaphylactic reactions to food, 2001-2006. J Allergy Clin Immunol 2007; 119:1016-8.
7. Pumphrey R, Gowland H. Further fatal allergic reactions to food in the United Kingdom, 1999-2006. J Allergy Clin Immunol 2007; 119:1018-9.
8. Munoz-Furlong A. Daily coping strategies for patients and their families. Pediatrics 2003; 111:1654-6161.
9. Gowland MH. Food allergen avoidance - the patient's viewpoint. Allergy 2001; 56 (Suppl. 67):117-20.
10. Greenberger PA. Epinephrine for anaphylaxis. Ann Allergy Asthma Immunol 2005; 94:515-6.
11. Sicherer SH, Simons FER, Williams PV et al. Self-injectable epinephrine for first-aid management of anaphylaxis. Pediatrics 2007; 119:638-46.
12. Song TT, Nelson MR, Chang JH, Engler RJ, Chowdhury BA. Adequacy of the epinephrine auto-injector needle length in delivering epinephrine to the intramuscular tissues. Ann Allergy Asthma Immunol 2005; 94:539-42.
13. Gold MS, Sainsbury R. First aid anaphylaxis management in children who were prescribed an epinephrine auto injector device (EpiPen). J Allergy Clin Immunol 2000; 106:171-6.
14. McLean-Tooke APC, Bethune CA, Fay AC, Spickett GP. Adrenaline in the treatment of anaphylaxis: what is the evidence? BMJ 2003; 327:1332-5.
15. Pongracic JA, Kim JS. Update on epinephrine for the treatment of anaphylaxis. Curr Opin Pediatr 2007; 19:94-8.
16. Sheikh A, Shehata YA, Brown SG, Simons FE. Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock. Cochrane Database Syst Rev 2008 (4): CD006312.
17. Goldberg A, Confino-Cohen R. Insect sting-inflicted systemic reactions: attitudes of patients with insect venom allergy regarding after-sting behaviour and proper administration of epinephrine. J Allergy Clin Immunol 2000; 106:1184-9.
18. Sicherer SH, Forman JA, Noone SA. Use assessment of self-administered epinephrine among food-allergic children and pediatricians. Pediatrics 2000; 105:359-62.
19. Sicherer SH, Simons FER. Quandaries in prescribing an emergency action plan and self-injectable epinephrine for first-aid management of anaphylaxis in the community. J Allergy Clin Immunol 2005; 115:575-83.
20. Kemp SF, Lockey RF, Simons FER. Epinephrine: the drug of choice for anaphylaxis - a statement of the World Allergy Organization. Allergy 2008; 63:1061-70.
21. Simons FER, Clark S, Camargo CA. Anaphylaxis in the community: learning from the survivors. J Allergy Clin Immunol 2009; 124:301-6.
22. Kim JS, Sinacore JM, Pongracic JA. Parental use of EpiPen for children with food allergies. J Allergy Clin Immunol 2005; 116:164-8.
23. Frew AJ. What are the 'ideal' features of an adrenaline (epinephrine) auto-injector in the treatment of anaphylaxis? Allergy 2011; 66:15-24.
24. Giacomini MK, Cook DJ. Users' guides to the Medical Literature XXIII. Qualitative Research in Health Care A. Are the results of the study valid? JAMA 2000; 284:357-62.
25. Gallagher M, Worth A, Sheikh A. Clinical allergy has much to gain from engagement with qualitative research. Allergy 2009; 64:1117-20.
26. Strauss A, Corbin J. Basics of qualitative research: Techniques and procedures for developing grounded theory. Newbury Park, CA: Sage, 1998.
27. Soar J, Pumphrey R, Cant A et al. Emergency treatment of anaphylactic reactions-guidelines for healthcare providers. Resuscitation 2008; 77:157-69.
28. QSR International Pty Ltd. NVivo qualitative data analysis software. Version 8. QSR International Pty Ltd, 2008.
29. Avery AJ, Sheikh A, Hurwitz B et al. Safer medicines management in primary care. Br J Gen Pract 2002; 52 (Suppl.):S17-22.
30. Blyth TP, Sundrum R. Adrenaline auto-injectors and schoolchildren: a community based study. Arch Dis Child 2002; 86:26-7.
31. Singh J, Aszkenasy OM. Prescription of adrenaline auto-injectors for potential anaphylaxis - a population survey. Public Health 2003; 117:256-9.
32. Lyons AC, Forde E. Food allergy in young adults: perceptions and psychological effects. J Health Psychol 2004; 9:497-504.
33. ®. Richmond, VA, USA. Available at (accessed 23 March 2010).
34. Giacomini MK, Cook DJ. Users' Guides to the Medical Literature XXIII. Qualitative Research in Health Care B. What are the results and how do they help me care for my patients? JAMA 2000; 284:478-82.
35. Malterud K. Qualitative research: standards, challenges, and guidelines. Lancet 2001; 358:483-8.
36. DunnGalvin A, Gaffney A, Hourihane JO'B. Developmental pathways in food allergy: a new theoretical framework. Allergy 2009; 64:560-8.
37. Rosen JP. Empowering patients with a history of anaphylaxis to use an epinephrine autoinjector without fear. Ann Allergy Asthma Immunol 2006; 97:418.
38. Rawas-Qalaji MM, Simons FER, Simons KJ. Sublingual epinephrine tablets versus intramuscular injection of epinephrine: dose equivalence for potential treatment of anaphylaxis. J Allergy Clin Immunol 2006; 117:398-403.