Condensed bridgehead nitrogen heterocyclic systems: Synthesis and evaluation of isatinyl thiazole derivatives as anti-Mycobacterium tuberculosis agents and dTDP-rhamnose inhibitors

Der Pharma Chemica

Volumn 3, Issue 2, 2011, Pages 418-432

  Dighe, Rajendra D ^a   Rohom, Sheetal S ^b   Dighe, Prashant D ^c   Shiradkar, Mahendra R ^d  

^a Amrutvahini College of Pharmacy   (India)

^b Sangamner College   (India)

^c Micro Labs Ltd   (India)

^d DR REDDY'S LABORATORIES LTD   (India)

Author keywords

Azetidinone derivative; Broth microdilution assay; Thiazolidinone derivatives; Well diffusion method

Indexed keywords

4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (2 CHLOROBENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (2 FLUOROBENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (2 NITROBENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (3 CHLORO 2 OXO 4 PHENYL AZETIDIN 1 YL) AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (3 CHLORO 4 OXO 2 SUBSTITUTED AZETIDIN 1 YL) AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (3 NITROBENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (3,4,5 TRIMETHOXY BENZYLIDENE) HYDRAZINE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (4 CHLOROBENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (4 DIMETHYL AMINO BENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (4 FLUOROBENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (4 HYDROXYBENZYLIDENE) HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (4 OXO 2 PHENYLTHIAZOLIDIN 3 YL) AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID (4 OXO 2 SUBSTITUTED PHENYLTHIAZOLIDIN 3 YL) AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO (4 DIMETHYLAMINOPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 (2 CHLOROPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 (2 FLUOROPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 (2 NITROPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 (3 NITROPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 (4 CHLOROPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 (4 FLUOROPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 (4 HYDROXYPHENYL) 4 OXO AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID [3 CHLORO 2 OXO 4 (3,4,5 TRIMETHOXYPHENY) AZETIDIN 1 YL] AMIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID BENZYLIDENE HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID BENZYLIDENE SUBSTITUTED HYDRAZIDE; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID ETHYL ESTER; 4 METHYL 2 (2 OXO 1,2 DIHYDRO INDOL 3 YLIDENEAMINO) THIAZOLE 5 CARBOXYLIC ACID HYDRAZIDE; ANTIMYCOBACTERIAL AGENT; ETHYL 2 AMINO 4 METHYLTHIAZOL 5 CARBOXYLATE; ISATINYL THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTITUBERCULAR ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

EID: 79955742861     PISSN: None     EISSN: 0975413X     Source Type: Journal    
DOI: None     Document Type: Article

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