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Volumn 37, Issue 4, 2002, Pages 323-332
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Synthesis and antibacterial activity of dual-action agents of a β-lactam antibiotic with cytotoxic agent mitozolomide or temozolomide
a
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Author keywords
lactam; Antibacterial; Cytotoxic; Dual action; Tetrazinone
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Indexed keywords
2 CARBOXYL 5 SULFOXIDE 7 (2 THIEN 2 YL)ACETAMIDO 2 CEPHEM 3 METHYL 3 (2 CHLOROETHYL) 4 OXOIMIDAZO[5,1 D][1,2,3,5]TETRAZINE 8 CARBOXYLIC ACID;
2 CARBOXYL 5 SULFOXIDE 7 (2 THIEN 2 YL)ACETAMIDO 2 CEPHEM 3,3 DIMETHYL 4 OXOIMIDAZO[5,1 D][1,2,3,5]TETRAZINE 8 CARBOXYLIC ACID;
2 CARBOXYL 7 PHENOXYACETAMIDE 5 SULFOXIDE 2 CEPHEM 3,3 DIMETHYL 4 OXOIMIDAZO[5,1 D][1,2,3,5]TETRAZINE 8 CARBOXYLIC ACID;
2 CARBOXYL 7 PHENOXYACETAMIDO 5 SULFOXIDE 2 CEPHEM 3 METHYL 3 (2 CHLOROETHYL) 4 OXOIMIDAZO[5,1 D][1,2,3,5]TETRAZINE 8 CARBOXYLIC ACID;
2 CARBOXYL 7 PHENYLACETAMIDO 5 SULFOXIDE 2 CEPHEM 3 METHYL 3 (2 CHLOROETHYL) 4 OXOIMIDAZO[5,1 D][1,2,3,5]TETRAZINE 8 CARBOXYLIC ACID;
2 CARBOXYL 7 PHENYLACETAMIDO 5 SULFOXIDE 2 CEPHEM 3,3 DIMETHYL 4 OXOIMIDAZO[5,1 D][1,2,3,5]TETRAZINE 8 CARBOXYLIC ACID;
6 [2 (3,5 DIOXO 1,2,4 TRIAZINE 6 CARBOXAMIDO) 2 (4 HYDROXYPHENYL)ACETAMIDO]PENICILLANIC ACID;
7 [DEXTRO 2 (3 METHYL 4 OXO IMIDAZO[5,1 D] 1,2,3,5 TETRAZINE 8 CARBOXYL)AMINO 2 PHENYLACETAMIDO] 3 METHYL 8 OXO 5 THIA AZABICYCLO[4,2 O]OCT 2 ENE 2 CARBOXYLIC ACID;
7 [DEXTRO 2 [3 (2 CHLOROETHYL) 4 OXO IMIDAZO[5,1 D] 1,2,3,5 TETRAZINE 8 CARBOXYL]AMINO 2 PHENYLACETAMIDO] 3 METHYL 8 OXO 5 THIA AZABICYCLO[4,2 O]OCT 2 ENE 2 CARBOXYLIC ACID;
ALPHA [(3 METHYL 4 OXO IMIDAZO[5,1 D] 1,2,3,5 TETRAZINE 8 CARBOXYL)AMINO 4 HYDROXYBENZYL]PENICILLIN;
ALPHA [(3 METHYL 4 OXO IMIDAZO[5,1 D] 1,2,3,5 TETRAZINE 8 CARBOXYL)AMINO BENZYL]PENICILLIN;
ALPHA [[3 (2 CHLOROETHYL) 4 OXO IMIDAZO[5,1 D] 1,2,3,5 TETRAZINE 8 CARBOXYL)AMINO 4 HYDROXYBENZYL]PENICILLIN;
ALPHA [[3 (2 CHLOROETHYL) 4 OXO IMIDAZO[5,1 D] 1,2,3,5 TETRAZINE 8 CARBOXYL)AMINOBENZYL]PENICILLIN;
AMOXICILLIN;
AMPICILLIN;
ANTIBIOTIC AGENT;
BETA LACTAM ANTIBIOTIC;
CEFALEXIN;
CLAVULANIC ACID;
FLEROXACIN DEACETYLCEFOTAXIME ESTER;
MITOZOLOMIDE;
PIPERACILLIN;
PIPERAZINE;
SULBACTAM;
SULTAMICILLIN;
TAZOBACTAM;
TEMOZOLOMIDE;
UNCLASSIFIED DRUG;
ANTIBACTERIAL ACTIVITY;
ANTIBIOTIC SENSITIVITY;
ARTICLE;
BACTERIAL STRAIN;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG EFFECT;
DRUG MECHANISM;
DRUG POTENTIATION;
DRUG SYNTHESIS;
NONHUMAN;
PENICILLIN RESISTANCE;
SENSITIVITY ANALYSIS;
SERRATIA MARCESCENS;
ANTI-BACTERIAL AGENTS;
ANTINEOPLASTIC AGENTS;
BETA-LACTAMS;
DACARBAZINE;
DRUG RESISTANCE, BACTERIAL;
GRAM-NEGATIVE BACTERIA;
GRAM-POSITIVE BACTERIA;
MICROBIAL SENSITIVITY TESTS;
NITROGEN MUSTARD COMPOUNDS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0037023579
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/S0223-5234(01)01331-9 Document Type: Article |
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Times cited : (23)
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References (22)
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