Otx2 promotes the survival of damaged adult retinal ganglion cells and protects against excitotoxic loss of visual acuity in vivo

Journal of Neuroscience

Volumn 31, Issue 14, 2011, Pages 5495-5503

  Ibad, Raoul Torero ^a   Rheey, Jinguen ^a   Mrejen, Sarah ^a   Forster, Valérie ^b   Picaud, Serge ^b   Prochiantz, Alain ^a   Moya, Kenneth L ^a  

^a ECOLE NORMALE SUPÉRIEURE   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR OTX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CELL DAMAGE; CELL LOSS; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; EXCITOTOXICITY; MALE; MOUSE; NERVE CELL; NEUROFILAMENT; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA GANGLION CELL; VISUAL IMPAIRMENT;

ANALYSIS OF VARIANCE; ANIMALS; CELL COUNT; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; N-METHYLASPARTATE; NEUROFILAMENT PROTEINS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; OLIGOPEPTIDES; OPTOMETRY; OTX TRANSCRIPTION FACTORS; RATS; RATS, LONG-EVANS; RETINA; RETINAL GANGLION CELLS; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTOR BRN-3A; VISUAL ACUITY;

EID: 79955729887     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0187-11.2011     Document Type: Article

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