Multiplex immunoassay for Lyme disease using VlsE1-IgG and pepC10-IgM antibodies: Improving test performance through bioinformatics

Clinical and Vaccine Immunology

Volumn 18, Issue 5, 2011, Pages 851-859

  Porwancher, Richard B ^a,b   Hagerty, C Greg ^a   Fan, Jianqing ^c   Landsberg, Lisa ^b   Johnson, Barbara J B ^d   Kopnitsky, Mark ^e   Steere, Allen C ^f   Kulas, Karen ^g   Wong, Susan J ^g  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b PC   (United States)

^c Princeton University   (United States)

^d NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^e Zeus Scientific Inc   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g WADSWORTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; MICROSPHERE; PROTEIN PEPC10; RECOMBINANT ANTIGEN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VARIABLE MAJOR PROTEIN LIKE SEQUENCE 1;

ANTIBODY BLOOD LEVEL; ARTICLE; BIOINFORMATICS; BORRELIA BURGDORFERI; CONTROLLED STUDY; CONVALESCENCE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; ENZYME IMMUNOASSAY; FALSE POSITIVE RESULT; HUMAN; INTERMETHOD COMPARISON; LYME DISEASE; MAJOR CLINICAL STUDY; NONHUMAN; PERFORMANCE MEASUREMENT SYSTEM; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; WESTERN BLOTTING;

ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CLINICAL LABORATORY TECHNIQUES; HUMANS; IMMUNOASSAY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LIPOPROTEINS; LYME DISEASE; MICROSPHERES; ROC CURVE; SENSITIVITY AND SPECIFICITY;

EID: 79955729254     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00409-10     Document Type: Article

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