The consequences of overdiagnosis and overtreatment of Lyme disease: An observational study

Annals of Internal Medicine

Volumn 128, Issue 5, 1998, Pages 354-362

  Reid, M Carrington ^a   Schoen, Robert T ^b   Evans, Janine ^b   Rosenberg, Jennifer C ^c   Horwitz, Ralph I ^b  

^a Vet Aff Connecticut Hlthcare S   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANTIBIOTIC THERAPY; ARTICLE; EPIGASTRIC PAIN; FEMALE; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN TISSUE; LYME DISEASE; MAJOR CLINICAL STUDY; MALE; NEUTROPENIA; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; SELF REPORT; VAGINITIS;

EID: 0032030801     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-128-5-199803010-00003     Document Type: Article

References (27)

1. Steere AC, Malawista SE, Snydman DR, Shope RE, Andiman WA, Steele FM. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities. Arthritis Rheum. 1977;20:7-17.
2. Steere AC. Lyme disease. N Engl J Med. 1989;321:586-96.
3. Dattwyler RJ, Volkman DJ, Conaty SM, Platkin SP, Luft BJ. Amoxycillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis. Lancet. 1990;336:1404-6.
4. Steere AC, Hutchinson GJ, Rahn DW, Sigal LH, Craft JE, DeSanna ET, et al. Treatment of the early manifestations of Lyme disease. Ann Intern Med. 1983;99:22-6.
5. Asch ES, Bujak DI, Weiss M, Peterson MG, Weinstein A. Lyme disease: an infectious and postinfectious syndrome. J Rheumatol. 1994;21:454-61.
6. Feder HM Jr, Hunt MS. Pitfalls in the diagnosis and treatment of Lyme disease in children. JAMA. 1995;274:66-8.
7. Rose CD, Fawcett PT, Gibney KM, Doughty RA. The overdiagnosis of Lyme disease in children residing in an endemic area. Clin Pediatr (Phila). 1994;33:663-8.
8. Steere AC, Taylor E, McHugh GL, Logigian EL. The overdiagnosis of Lyme disease. JAMA. 1993;269:1812-6.
9. Sigal LH. Summary of the first 100 patients seen at a Lyme disease referral center. Am J Med. 1990;88:577-81.
10. Bakken LL, Case KL, Callister SM, Bourdeau NJ, Schell RF. Performance of 45 laboratories participating in a proficiency testing program for Lyme disease serology. JAMA. 1992;268:891-5.
11. Schwartz BS, Goldstein MD, Ribeiro JM, Schulze TL, Shahied SI. Antibody testing in Lyme disease. A comparison of results in four laboratories. JAMA. 1989;262:3431-4.
12. Sigal LH. Anxiety and persistence of Lyme disease. Am J Med. 1995;98(4A): 74S-8S.
13. Sigal LH. The Lyme disease controversy. Social and financial costs of misdiagnosis and mismanagement. Arch Intern Med. 1996;156:1493-500.
14. Vital and Health Statistics. Questionnaires from the National Health Interview Survey. Hyattsville, MD: US Dept of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Center for Health Statistics; 1993. DHHS publication 93-1307.
15. Mirowsky J, Ross CE. Age and depression. J Health Soc Behav. 1992;33: 187-205.
16. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress.J Health Soc Behav. 1983;24:385-96.
17. Cohen S, Kessler RC, Gordon LU, eds. Measuring Stress: A Guide for Health and Social Scientists. New York: Oxford Univ Pr; 1995.
18. Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med. 1991;325:606-12.
19. Rahn DW, Malawista SE. Lyme disease: recommendations for diagnosis and treatment. Ann Intern Med. 1991;114:472-81.
20. Physicians' Desk Reference. Oradell, NJ: Medical Economics; 1997.
21. American Hospital Formulary Service. Drug Information. Bethesda, MD: American Society of Hospital Pharmacists; 1996.
22. Craft JE, Grodzicki RL, Steere AC. Antibody response in Lyme disease: evaluation of diagnostic tests. J Infect Dis. 1984;149:789-95.
23. Johnson BJ, Robbins KE, Bailey RE, Cao BL, Sviat SL, Craven RB, et al. Serodiagnosis of Lyme disease: accuracy of a two-step approach using a flagella-based ELISA and immunoblotting. J Infect Dis. 1996;174:346-53.
24. Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR Morb Mortal Wkly Rep. 1995;44:590-1.
25. Dinerman H, Steere AC. Lyme disease associated with fibromyalgia. Ann Intern Med. 1992;117:281-5.
26. Hsu V, Patella SJ, Sigal LH. "Chronic Lyme disease" as the incorrect diagnosis in fibromyalgia. Arthritis Rheum. 1993;36:1493-500.
27. From the Centers for Disease Control and Prevention. Lyme Disease - United States, 1995. JAMA. 1996;276:274.