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Volumn 137, Issue 5, 2011, Pages 897-905

Short-term anastrozole therapy reduces Ki-67 and progesterone receptor expression in invasive breast cancer: A prospective, placebo-controlled, double-blind trial

Author keywords

Anastrozole; Breast cancer; Estrogen receptor; Ki 67; Progesterone receptor; Short term hormone therapy

Indexed keywords

ANASTROZOLE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; KI 67 ANTIGEN; PLACEBO; PROGESTERONE RECEPTOR; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; TAMOXIFEN;

EID: 79955702492     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-010-0950-4     Document Type: Article
Times cited : (3)

References (44)
  • 1
    • 0032478958 scopus 로고    scopus 로고
    • Relationship between estrogen levels, use of hormone replacement therapy, and breast cancer
    • doi:10.1093/jnci/90.11.814
    • Colditz G (1998) Relationship between estrogen levels, use of hormone replacement therapy, and breast cancer. J Natl Cancer Inst 90(11):814-823. doi:10.1093/jnci/90.11.814
    • (1998) J Natl Cancer Inst , vol.90 , Issue.11 , pp. 814-823
    • Colditz, G.1
  • 2
    • 27744576150 scopus 로고    scopus 로고
    • Proliferative markers as prognostic and predictive tools in early breast cancer: Where are we now?
    • doi:10.1093/annonc/mdi352
    • Colozza M, Azambuja E, Cardoso F, Sotiriou C, Larsimont D, Piccart MJ (2005) Proliferative markers as prognostic and predictive tools in early breast cancer: where are we now? Ann Oncol 16(11):1723-1739. doi:10.1093/annonc/mdi352
    • (2005) Ann Oncol , vol.16 , Issue.11 , pp. 1723-1739
    • Colozza, M.1    Azambuja, E.2    Cardoso, F.3    Sotiriou, C.4    Larsimont, D.5    Piccart, M.J.6
  • 3
    • 0034131068 scopus 로고    scopus 로고
    • The effects of neoadjuvant anastrozole (arimidex) on tumor volume in postmenopausal women with breast cancer: A randomized, double-blind, single- Center study
    • Dixon JM, Renshaw L, Bellamy C, Stuart M, Hoctin-Boes G, Miller WR (2000) The effects of neoadjuvant anastrozole (arimidex) on tumor volume in postmenopausal women with breast cancer: a randomized, double-blind, single-center study. Clin Cancer Res 6(6):2229-2235 (Pubitemid 30399188)
    • (2000) Clinical Cancer Research , vol.6 , Issue.6 , pp. 2229-2235
    • Dixon, J.M.1    Renshaw, L.2    Bellamy, C.3    Stuart, M.4    Hoctin-Boes, G.5    Miller, W.R.6
  • 4
    • 0037240118 scopus 로고    scopus 로고
    • Preoperative models to evaluate endocrine strategies for breast cancer
    • Dowsett M (2003) Preoperative models to evaluate endocrine strategies for breast cancer. Clin Cancer Res 9(1):502s-510s
    • (2003) Clin Cancer Res , vol.9 , Issue.1
    • Dowsett, M.1
  • 5
    • 12144280241 scopus 로고    scopus 로고
    • Biomarker investigations from the atac trial: The role of ta01
    • Dowsett M (2004) Biomarker investigations from the atac trial: the role of ta01. Breast Cancer Res Treat 87(1):11-18
    • (2004) Breast Cancer Res Treat , vol.87 , Issue.1 , pp. 11-18
    • Dowsett, M.1
  • 6
    • 58149340543 scopus 로고    scopus 로고
    • Emerging biomarkers and new understanding of traditional markers in personalized therapy for breast cancer
    • doi: 10.1158/1078-0432.ccr-08-0974
    • Dowsett M, Dunbier AK (2008) Emerging biomarkers and new understanding of traditional markers in personalized therapy for breast cancer. Clin Cancer Res 14(24):8019-8026. doi: 10.1158/1078-0432.ccr-08-0974
    • (2008) Clin Cancer Res , vol.14 , Issue.24 , pp. 8019-8026
    • Dowsett, M.1    Dunbier, A.K.2
  • 9
    • 28044459820 scopus 로고    scopus 로고
    • The biology of steroid hormones and endocrine treatment of breast cancer
    • DOI 10.1016/j.breast.2005.08.019, PII S096097760500189X, 9th International Conference on Primary Therapy of Early Breast Cancer
    • Dowsett M, Elizabeth F, Deborah D, Ben H (2005b) The biology of steroid hormones and endocrine treatment of breast cancer. Breast (Edinburgh, Scotland) 14(6):452-457 (Pubitemid 41683566)
    • (2005) Breast , vol.14 , Issue.6 , pp. 452-457
    • Dowsett, M.1    Folkerd, E.2    Doody, D.3    Haynes, B.4
  • 13
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • EBCTCG
    • EBCTCG (1998) Tamoxifen for early breast cancer: An overview of the randomised trials. The Lancet 351(9114):1451-1467
    • (1998) The Lancet , vol.351 , Issue.9114 , pp. 1451-1467
  • 14
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • EBCTCG
    • EBCTCG (2005) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials. The Lancet 365(9472):1687-1717
    • (2005) The Lancet , vol.365 , Issue.9472 , pp. 1687-1717
  • 15
    • 34948838922 scopus 로고    scopus 로고
    • Letrozole in the neoadjuvant setting: The P024 trial
    • DOI 10.1007/s10549-007-9701-x
    • Ellis M, Ma C (2007) Letrozole in the neoadjuvant setting: The p024 trial. Breast Cancer Res Treat 105:33-43 (Pubitemid 47524802)
    • (2007) Breast Cancer Research and Treatment , vol.105 , Issue.1 SUPPL. , pp. 33-43
    • Ellis, M.J.1    Ma, C.2
  • 17
    • 0024044464 scopus 로고
    • Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: Findings from national surgical adjuvant breast and bowel project protocol b-06
    • Fisher B, Redmond C, Fisher E, Caplan R (1988) Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: findings from national surgical adjuvant breast and bowel project protocol b-06. J Clin Oncol 6(7):1076-1087
    • (1988) J Clin Oncol , vol.6 , Issue.7 , pp. 1076-1087
    • Fisher, B.1    Redmond, C.2    Fisher, E.3    Caplan, R.4
  • 18
    • 0034901971 scopus 로고    scopus 로고
    • Influence of neoadjuvant anastrozole (Arimidex) on intratumoral estrogen levels and proliferation markers in patients with locally advanced breast cancer
    • Geisler J, Detre S, Berntsen H, Ottestad L, Lindtjørn B, Dowsett M, Lønning PE (2001) Influence of neoadjuvant anastrozole (arimidex) on intratumoral estrogen levels and proliferation markers in patients with locally advanced breast cancer. Clin Cancer Res 7(5):1230-1236 (Pubitemid 32708674)
    • (2001) Clinical Cancer Research , vol.7 , Issue.5 , pp. 1230-1236
    • Geisler, J.1    Detre, S.2    Berntsen, H.3    Ottestad, L.4    Lindtjorn, B.5    Dowsett, M.6    Lonning, P.E.7
  • 19
    • 4444258773 scopus 로고    scopus 로고
    • Steroidal hormones and proliferation, differentiation and apoptosis in breast cells
    • DOI 10.1016/j.maturitas.2004.06.009, PII S0378512204002051
    • Gompel A, Chaouat M, Hugol D, Forgez P (2004) Steroidal hormones and proliferation, differentiation and apoptosis in breast cells. Maturitas 49(1):16-24 (Pubitemid 39209367)
    • (2004) Maturitas , vol.49 , Issue.1 , pp. 16-24
    • Gompel, A.1    Chaouat, M.2    Hugol, D.3    Forgez, P.4
  • 20
    • 0037204192 scopus 로고    scopus 로고
    • Production and actions of estrogens
    • doi:10.1056/NEJMra000471
    • Gruber CJ, Tschugguel W, Schneeberger C, Huber JC (2002) Production and actions of estrogens. N Engl J Med 346(5):340-352. doi:10.1056/NEJMra000471
    • (2002) N Engl J Med , vol.346 , Issue.5 , pp. 340-352
    • Gruber, C.J.1    Tschugguel, W.2    Schneeberger, C.3    Huber, J.C.4
  • 21
    • 4544367117 scopus 로고    scopus 로고
    • Towards an integrated model for breast cancer etiology: The lifelong interplay of genes, lifestyle, and hormones
    • Hankinson S, Colditz G, Willett W (2004) Towards an integrated model for breast cancer etiology: the lifelong interplay of genes, lifestyle, and hormones. Breast Cancer Res 6(5):213-218
    • (2004) Breast Cancer Res , vol.6 , Issue.5 , pp. 213-218
    • Hankinson, S.1    Colditz, G.2    Willett, W.3
  • 22
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey JM, Clark GM, Osborne CK, Allred DC (1999) Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 17(5):1474
    • (1999) J Clin Oncol , vol.17 , Issue.5 , pp. 1474
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3    Allred, D.C.4
  • 23
    • 60749110936 scopus 로고    scopus 로고
    • Markers of endocrine sensitivity
    • Hayes D (2008) Markers of endocrine sensitivity. Breast Cancer Res 10(Suppl 4):S18
    • (2008) Breast Cancer Res , vol.10 , Issue.SUPPL. 4
    • Hayes, D.1
  • 24
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO (2000) The biochemistry of apoptosis. Nature 407(6805):770-776
    • (2000) Nature , vol.407 , Issue.6805 , pp. 770-776
    • Hengartner, M.O.1
  • 25
    • 0036022406 scopus 로고    scopus 로고
    • Clinical relevance of apoptotic markers in breast cancer not yet clear
    • DOI 10.1023/A:1016179530785
    • Jager JJ, Jansen RLH, Arends JW (2002) Clinical relevance of apoptotic markers in breast cancer not yet clear. Apoptosis 7(4):361-365 (Pubitemid 34832260)
    • (2002) Apoptosis , vol.7 , Issue.4 , pp. 361-365
    • Jager, J.J.1    Jansen, R.L.H.2    Arends, J.W.3
  • 26
  • 27
    • 0242499440 scopus 로고    scopus 로고
    • Aromatase inhibitors for breast cancer: Lessons from the laboratory
    • Johnston SRD, Dowsett M (2003) Aromatase inhibitors for breast cancer: lessons from the laboratory. Nat Rev Cancer 3(11):821-831 (Pubitemid 37376980)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.11 , pp. 821-831
    • Johnston, S.R.D.1    Dowsett, M.2
  • 28
    • 0028021955 scopus 로고
    • Molecular mechanisms of antiestrogen action in breast cancer
    • Jordan VC (1994) Molecular mechanisms of antiestrogen action in breast cancer. Breast Cancer Res Treat 31(1):41-52
    • (1994) Breast Cancer Res Treat , vol.31 , Issue.1 , pp. 41-52
    • Jordan, V.C.1
  • 29
  • 31
    • 0028115802 scopus 로고
    • Bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer
    • Leek RD, Kaklamanis L, Pezzella F, Gatter KC, Harris AL (1994) Bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer. Br J Cancer 69(1):135-139 (Pubitemid 24021836)
    • (1994) British Journal of Cancer , vol.69 , Issue.1 , pp. 135-139
    • Leek, R.D.1    Kaklamanis, L.2    Pezzella, F.3    Gatter, K.C.4    Harris, A.L.5
  • 32
    • 33751211861 scopus 로고    scopus 로고
    • Neoadjuvant use of hormonal therapy in elderly patients with early or locally advanced hormone receptor-positive breast cancer
    • DOI 10.1634/theoncologist.11-10-1081
    • Macaskill EJ, Renshaw L, Dixon JM (2006) Neoadjuvant use of hormonal therapy in elderly patients with early or locally advanced hormone receptor-positive breast cancer. Oncologist 11(10):1081-1088. doi:10.1634/theoncologist.11-10-1081 (Pubitemid 44788399)
    • (2006) Oncologist , vol.11 , Issue.10 , pp. 1081-1088
    • Macaskill, E.J.1    Renshaw, L.2    Dixon, J.M.3
  • 34
    • 0030758884 scopus 로고    scopus 로고
    • Ki-67 immunostaining in 322 primary breast cancers: Associations with clinical and pathological variables and prognosis
    • DOI 10.1002/(SICI)1097-0215(19970822)74:4<433::AID-IJC12>3.0.CO;2-A
    • Molino A, Micciolo R, Turazza M, Bonetti F, Piubello Q, Bonetti A, Nortilli R, Pelosi G, Cetto GL (1997) Ki-67 immunostaining in 322 primary breast cancers: associations with clinical and pathological variables and prognosis. Int J Cancer 74(4):433-437 (Pubitemid 27400164)
    • (1997) International Journal of Cancer , vol.74 , Issue.4 , pp. 433-437
    • Molino, A.1    Micciolo, R.2    Turazza, M.3    Bonetti, F.4    Piubello, Q.5    Bonetti, A.6    Nortilli, R.7    Pelosi, G.8    Cetto, G.L.9
  • 35
    • 69249137029 scopus 로고    scopus 로고
    • Biological determinants of endocrine resistance in breast cancer
    • Musgrove EA, Sutherland RL (2009) Biological determinants of endocrine resistance in breast cancer. Nat Rev Cancer 9(9):631-643
    • (2009) Nat Rev Cancer , vol.9 , Issue.9 , pp. 631-643
    • Musgrove, E.A.1    Sutherland, R.L.2
  • 36
    • 33751182887 scopus 로고    scopus 로고
    • Cyclin d1 and breast cancer
    • Edinburgh, Scotland
    • Pankaj GR, Alastair MT (2006) Cyclin d1 and breast cancer. Breast (Edinburgh, Scotland) 15(6):718-727
    • (2006) Breast , vol.15 , Issue.6 , pp. 718-727
    • Pankaj, G.R.1    Alastair, M.T.2
  • 37
    • 0034943218 scopus 로고    scopus 로고
    • Prognostic comparative study of S-phase fraction and Ki-67 index in breast carcinoma
    • DOI 10.1136/jcp.54.7.543
    • Pinto AE, André S, Pereira T, Nóbrega S, Soares J (2001) Prognostic comparative study of s-phase fraction and ki-67 index in breast carcinoma. J Clin Pathol 54(7):543-549. doi:10.1136/jcp.54.7.543 (Pubitemid 32642944)
    • (2001) Journal of Clinical Pathology , vol.54 , Issue.7 , pp. 543-549
    • Pinto, A.E.1    Andre, S.2    Pereira, T.3    Nobrega, S.4    Soares, J.5
  • 41
    • 0038210242 scopus 로고    scopus 로고
    • Aromatase inhibitors in breast cancer
    • DOI 10.1056/NEJMra023246
    • Smith IE, Dowsett M (2003) Aromatase inhibitors in breast cancer. N Engl J Med 348(24):2431-2442. doi:10.1056/NEJMra023246 (Pubitemid 36682823)
    • (2003) New England Journal of Medicine , vol.348 , Issue.24 , pp. 2431-2442
    • Smith, I.E.1    Dowsett, M.2
  • 42
    • 2942533005 scopus 로고    scopus 로고
    • Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients
    • DOI 10.1038/sj.bjc.6601831
    • Stendahl M, Kronblad A, Ryden L, Emdin S, Bengtsson NO, Landberg G (2004) Cyclin d1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients. Br J Cancer 90(10):1942-1948 (Pubitemid 38746334)
    • (2004) British Journal of Cancer , vol.90 , Issue.10 , pp. 1942-1948
    • Stendahl, M.1    Kronblad, A.2    Ryden, L.3    Emdin, S.4    Bengtsson, N.O.5    Landberg, G.6
  • 44
    • 33644834789 scopus 로고    scopus 로고
    • Common markers of proliferation
    • Whitfield ML, George LK, Grant GD, Perou CM (2006) Common markers of proliferation. Nat Rev Cancer 6 (2):99-106. doi:http://www.nature.com/nrc/ journal/v6/n2/suppinfo/nrc1802-S1.html
    • (2006) Nat Rev Cancer , vol.6 , Issue.2 , pp. 99-106
    • Whitfield, M.L.1    George, L.K.2    Grant, G.D.3    Perou, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.