Cyclic mechanical stretch downregulates IL-1β-induced COX-2 expression and PGE2 production in rheumatoid arthritis fibroblast-like synoviocytes

Connective Tissue Research

Volumn 52, Issue 3, 2011, Pages 190-197

  Wang, Ping ^a   You, Xin ^b   Yan, Yan ^a   Singh, Gurinder K ^a   Li, Xian ^a   Zhou, Wei ^a   Liu, Wanqian ^a   Zhang, Feifei ^a   Lv, Yonggang ^a   Yang, Li ^a  

^a CHONGQING UNIVERSITY   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

cyclooxygenase 2; fibroblast like synoviocytes; I B ; I B ; matrix metalloproteinase; NF B; prostaglandin E2; rheumatoid arthritis

Indexed keywords

CYCLOOXYGENASE 2; I KAPPA B ALPHA; I KAPPA B BETA; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MESSENGER RNA; PROSTAGLANDIN E2;

ARTICLE; CYTOPLASM; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST LIKE SYNOVIOCYTE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MECHANICAL STRESS; PROSTAGLANDIN SYNTHESIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; WESTERN BLOTTING;

ARTHRITIS, RHEUMATOID; CYCLOOXYGENASE 2; CYTOPLASM; DINOPROSTONE; DOWN-REGULATION; ENZYME INDUCTION; FIBROBLASTS; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 1; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; STRESS, MECHANICAL; SYNOVIAL FLUID;

EID: 79955691720     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.3109/03008207.2010.508853     Document Type: Article

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