Serum gamma-glutamyl transferase within its normal concentration range is related to the presence of impaired fasting glucose and diabetes among Japanese community-dwelling persons

Endocrine Research

Volumn 36, Issue 2, 2011, Pages 64-73

  Kawamoto, Ryuichi ^a,b   Tabara, Yasuharu ^a   Kohara, Katsuhiko ^a   Miki, Tetsuro ^a   Ohtsuka, Nobuyuki ^b   Kusunoki, Tomo ^a,b   Takayama, Shouzo ^a   Abe, Masanori ^a  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Seiyo Municipal Nomura Hospital   (Japan)

Author keywords

Diabetes; Gamma glutamyl transferase; Impaired fasting glucose; Insulin resistance; Risk factor

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; CREATININE; GAMMA GLUTAMYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HIGH MOLECULAR WEIGHT ADIPONECTIN; IMMUNOREACTIVE INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URIC ACID;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; AUTOANALYZER; BODY MASS; CHOLESTEROL BLOOD LEVEL; CLINICAL ASSESSMENT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS OF MINIMAL ASSESSMENT OF INSULIN RESISTANCE; HUMAN; INSULIN BLOOD LEVEL; JAPANESE; MALE; MEDICAL EXAMINATION; OSCILLOMETRY; OXIDATIVE STRESS; PRIORITY JOURNAL; RISK FACTOR; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; URIC ACID BLOOD LEVEL;

ADULT; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; FASTING; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; GLUCOSE INTOLERANCE; HUMANS; JAPAN; MALE; MIDDLE AGED; ODDS RATIO; OXIDATIVE STRESS; REFERENCE VALUES;

EID: 79955687911     PISSN: 07435800     EISSN: 15324206     Source Type: Journal    
DOI: 10.3109/07435800.2010.534756     Document Type: Article

References (37)

1. Whitfield JB. Gamma glutamyl transferase. Crit Rev Clin Lab Sci 2001;38:263-355. (Pubitemid 32826505)
2. Emdin M, Pompella A, Paolicchi A. Gamma-glutamyl transferase, atherosclerosis, and cardiovascular disease: triggering oxidative stress within the plaque. Circulation 2005;112:2078-2080. (Pubitemid 41475797)
3. Poikolainen K, Vartiainen E. Determinants of gamma-glutamyl transferase: positive interaction with alcohol and body mass index, negative association with coffee. Am J Epidemiol 1997;146:1019-1024. (Pubitemid 28030419)
4. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231.
5. Lee DH, Jacobs DR Jr., Gross M, et al. Gamma-glutamyltransferase is a predictor of incident diabetes and hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Clin Chem 2003;49:1358-1366. (Pubitemid 36900623)
6. Shankar A, Li J. Association between serum gamma-glutamyl transferase level and prehypertension among US adults. Circ J 2007;71:1567-1572. (Pubitemid 47529658)
7. André P, Balkau B, Vol S, Charles MA, Eschwège E; DESIR Study Group. Gamma-glutamyl transferase activity and development of the metabolic syndrome (International Diabetes Federation Definition) in middle-aged men and women: Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort. Diabetologia 2006;49:2599-2603.
8. André P, Balkau B, Vol S, Charles MA, Eschwège E; DESIR Study Group. Gamma-glutamyltransferase activity and development of the metabolic syndrome (International Diabetes Federation Definition) in middle-aged men and women: Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort. Diabetes Care 2007;30:2355-2361. (Pubitemid 47364644)
9. Nakanishi N, Suzuki K, Tatara K. Serum gamma-glutamyl transferase and risk of metabolic syndrome and type 2 diabetes in middle-aged Japanese men. Diabetes Care 2004;27:1427-1432. (Pubitemid 38679993)
10. Rantala AO, Lilja M, Kauma H, Savolainen MJ, Reunanen A, Kesäniemi YA. Gamma-glutamyl transpeptidase and the metabolic syndrome. J Intern Med 2000;248:230-238.
11. Sakugawa H, Nakayoshi T, Kobashigawa K, et al. Metabolic syndrome is directly associated with gamma glutamyl transpeptidase elevation in Japanese women. World J Gastroenterol 2004;10: 1052-1055. (Pubitemid 38461393)
12. Lee DS, Evans JC, Robins SJ, et al. Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2007;27:127-133. (Pubitemid 46360389)
13. Kawamoto R, Kohara K, Tabara Y, Kusunoki T, Otsuka N, Miki T. Association between serum gamma-glutamyl transferase level and prehypertension among community-dwelling men. Tohoku J Exp Med 2008;216:213-221.
14. Kawamoto R, Kohara K, Tabara Y, Miki T, Otsuka N. Serum gamma-glutamyl transferase levels are associated with metabolic syndrome in community-dwelling individuals. J Atheroscler Thromb 2009;16:355-362.
15. Sabanayagam C, Shankar A, Li J, Pollard C, Ducatman A. Serum gamma-glutamyl transferase level and diabetes mellitus among US adults. Eur J Epidemiol 2009;24:369-373.
16. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502.
17. World Health Organization. Definition, Diagnosis, and Classification of Diabetes Mellitus and Its Complications: Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus. Geneva, World Health Organization, 1999.
18. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419. (Pubitemid 15018832)
19. The Japanese Society of Nephrology. Japanese version of GFR estimation. http://www.jsn.or.jp, 2007. Accessed October 29.
20. Shin JY, Lim JH, Koh DH, et al. Serum gamma-glutamyltransferase levels and the risks of impaired fasting glucose in healthy men: a 2-year follow-up. J Prev Med Public Health 2006;39:353-358.
21. Nakanishi N, Nishina K, Li W, Sato M, Suzuki K, Tatara K. Serum gamma-glutamyltransferase and development of impaired fasting glucose or type 2 diabetes in middle-aged Japanese men. J Intern Med 2003;254:287-295. (Pubitemid 37070231)
22. Jimba S, Nakagami T, Oya J, Wasada T, Endo Y, Iwamoto Y. Increase in gamma-glutamyltransferase level and development of established cardiovascular risk factors and diabetes in Japanese adults. Metab Syndr Relat Disord 2009;7:411-418.
23. Fain JN. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm 2006;74:443-477.
24. Lee DH, Jacobs DR Jr. Association between serum gamma-glutamyltransferase and C-reactive protein. Atherosclerosis 2005;178:327-330. (Pubitemid 40193447)
25. Lee YJ, Kim JK, Lee JH, Lee HR, Kang DR, Shim JY. Association of serum gamma-glutamyltransferase with C-reactive protein levels and white blood cell count in Korean adults. Clin Chem Lab Med 2008;46:1410-1415.
26. Hotamisligil GS. Inflammatory pathways and insulin action. Int J Obes Relat Metab Disord 2003;27(Suppl 3):S53-S55. (Pubitemid 38019190)
27. Kang YH, Min HK, Son SM, Kim IJ, Kim YK. The association of serum gamma glutamyltransferase with components of the metabolic syndrome in the Korean adults. Diabetes Res Clin Pract 2007;77:306-313. (Pubitemid 46670410)
28. Ikai E, Honda R, Yamada Y. Serum gamma-glutamyl transpeptidase level and blood pressure in nondrinkers: a possible pathogenetic role of fatty liver in obesity-related hypertension. J Hum Hypertens 1994;8:95-100. (Pubitemid 24065895)
29. Nilssen O, Førde OH. Seven-year longitudinal population study of change in gamma-glutamyltransferase: the Tromsø Study. Am J Epidemiol 1994;139:787-792. (Pubitemid 24135782)
30. Verrijken A, Francque S, Mertens I, Talloen M, Peiffer F, Van Gaal L. Visceral adipose tissue and inflammation correlate with elevated liver tests in a cohort of overweight and obese patients. Int J Obes (Lond) 2010;34:899-907.
31. Lee DH, Blomhoff R, Jacobs DR Jr. Is serum gamma-glutamyltransferase a marker of oxidative stress? Free Radic Res 2004;38:535-539. (Pubitemid 38697087)
32. Simão AN, Dichi JB, Barbosa DS, Cecchini R, Dichi I. Influence of uric acid and gamma-glutamyltransferase on total antioxidant capacity and oxidative stress in patients with metabolic syndrome. Nutrition 2008;24:675-681.
33. Stark AA, Zeiger E, Pagano DA. Glutathione metabolism by gamma-glutamyl transpeptidase leads to lipid peroxidation: characterization of the system and relevance to hepatocarcinogenesis. Carcinogenesis 1993;14:183-189. (Pubitemid 23143391)
34. Karp DR, Shimooku K, Lipsky PE. Expression of gamma-glutamyl transpeptidase protects ramos B cells from oxidation-induced cell death. J Biol Chem 2001;276:3798-3804.
35. Dominici S, Paolicchi A, Corti A, Maellaro E, Pompella A. Prooxidant reactions promoted by soluble and cell-bound gamma-glutamyltransferase activity. Methods Enzymol 2005;401:484-501. (Pubitemid 43052409)
36. Maddux BA, See W, Lawrence JC Jr., Goldfine AL, Goldfine ID, Evans JL. Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by micromolar concentrations of alpha-lipoic acid. Diabetes 2001;50:404-410. (Pubitemid 32127299)
37. Matsuoka T, Kajimoto Y, Watada H et al. Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells. J Clin Invest 1997;99:144-150. (Pubitemid 27058305)