-
1
-
-
33847345910
-
2 receptor antagonist, [(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4- tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524)
-
DOI 10.1021/jm0603668
-
(a) Sturino, C. F.; Neill, G.; Lachance, N.; Boyd, M.; Bertgelette, C.; Labelle, M.; Li, L.; Roy, B.; Scheigetz, J.; Tsou, N.; Aubin, Y.; Bateman, K. P.; Chauret, N.; Day, S. H.; Levesque, J. F.; Seto, C.; Silva, J. H.; Trimble, L. A.; Carriere, M. C.; Denis, D.; Greig, G.; Kargman, S.; Lamontagne, S.; Mathieu, M. C.; Sawyer, N.; Slipetz, D.; Abraham, W. M.; Jones, T.; McAuliffe, M.; Piechuta, H.; Nicoll-Griffith, D. A.; Wang, Z.; Zamboni, R.; Young, R. N.; Metters, K. M. Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4- tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524). J. Med. Chem. 2007, 50, 794-806; (Pubitemid 46332991)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.4
, pp. 794-806
-
-
Sturino, C.F.1
O'Neill, G.2
Lachance, N.3
Boyd, M.4
Berthelette, C.5
Labelle, M.6
Li, L.7
Roy, B.8
Scheigetz, J.9
Tsou, N.10
Aubin, Y.11
Bateman, K.P.12
Chauret, N.13
Day, S.H.14
Levesque, J.-F.15
Seto, C.16
Silva, J.H.17
Trimble, L.A.18
Carriere, M.-C.19
Denis, D.20
Greig, G.21
Kargman, S.22
Lamontagne, S.23
Mathieu, M.-C.24
Sawyer, N.25
Slipetz, D.26
Abraham, W.M.27
Jones, T.28
McAuliffe, M.29
Piechuta, H.30
Nicoll-Griffith, D.A.31
Wang, Z.32
Zamboni, R.33
Young, R.N.34
Metters, K.M.35
more..
-
2
-
-
4644308019
-
Biomimetic enantioselective total synthesis of (-)-siccanin via the Pd-catalyzed asymmetric allylic alkylation (AAA) and sequential radical cyclizations
-
DOI 10.1021/ja048084p
-
(b) Trost, B. M.; Shen, H. C.; Surivet, J. P. Biomimetic enantioselective total synthesis of (-)-siccanin via the Pd-catalyzed asymmetric allylic alkylation (AAA) and sequential radical cyclizations. J. Am. Chem. Soc. 2004, 126, 12565-12579; (Pubitemid 39304936)
-
(2004)
Journal of the American Chemical Society
, vol.126
, Issue.39
, pp. 12565-12579
-
-
Trost, B.M.1
Shen, H.C.2
Surivet, J.-P.3
-
3
-
-
11444252699
-
Validation of lanthanide chiral shift reagents for determination of absolute configuration: Total synthesis of glisoprenin A
-
DOI 10.1021/ol048059o
-
(c) Adams, C. M.; Ghosh, I.; Kishi, Y. Validation of lanthanide chiral shift reagents for determination of absolute configuration: Total synthesis of glisoprenin A. Org. Lett. 2004, 6, 4723-4726; (Pubitemid 40081630)
-
(2004)
Organic Letters
, vol.6
, Issue.25
, pp. 4723-4726
-
-
Adams, C.M.1
Ghosh, I.2
Kishi, Y.3
-
4
-
-
0034075488
-
Structure-based design, synthesis, and biological evaluation of novel pyrrolyl aryl sulfones: HIV-1 non-nucleoside reverse transcriptase inhibitors active at nanomolar concentrations
-
DOI 10.1021/jm9901125
-
(d) Artico, M.; Silvestri, R.; Pagnozzi, E.; Bruno, B.; Novellino, E.; Greco, G.; Massa, S.; Ettorre, A.; Loi, A. G.; Scintu, F.; La Colla, P. Structure-based design, synthesis, and biological evaluation of novel pyrrolyl aryl sulfones: HIV-1 non-nucleoside reverse transcriptase inhibitors active at nanomolar concentrations. J. Med. Chem. 2000, 43, 1886-1891; (Pubitemid 30305021)
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, Issue.9
, pp. 1886-1891
-
-
Artico, M.1
Silvestri, R.2
Pagnozzi, E.3
Bruno, B.4
Novellino, E.5
Greco, G.6
Massa, S.7
Ettorre, A.8
Loi, A.G.9
Scintu, F.10
La Colla, P.11
-
6
-
-
4243937209
-
-
Chem. Abstr. 1989, 111, 129017;
-
(1989)
Chem. Abstr.
, vol.111
, pp. 129017
-
-
-
7
-
-
34547428610
-
Formation of linear copolymers of ethylene and acrylonitrile catalyzed by phosphine sulfonate palladium complexes
-
DOI 10.1021/ja0725504
-
(f) Kochi, T.; Noda, S.; Yoshimura, K.; Nozaki, K. Formation of linear Copolymers of ethylene and acrylonitrile catalyzed by phosphine sulfonate palladium complexes. J. Am. Chem. Soc. 2007, 129, 8948-8949; (Pubitemid 47171828)
-
(2007)
Journal of the American Chemical Society
, vol.129
, Issue.29
, pp. 8948-8949
-
-
Kochi, T.1
Noda, S.2
Yoshimura, K.3
Nozaki, K.4
-
8
-
-
15844384988
-
Synthesis and physical properties of highly sulfonated polyaniline
-
DOI 10.1021/ja952277i
-
(g) Wei, X. L.; Wang, Y. Z.; Long, S. M.; Bobeczko, C.; Epstein, A. J. Synthesis and physical properties of highly sulfonated polyaniline. J. Am. Chem. Soc. 1996, 118, 2545-2555. (Pubitemid 26130432)
-
(1996)
Journal of the American Chemical Society
, vol.118
, Issue.11
, pp. 2545-2555
-
-
Wei, X.-L.1
Wang, Y.Z.2
Long, S.M.3
Bobeczko, C.4
Epstein, A.J.5
-
9
-
-
0031046693
-
Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors
-
(a) Neamati, N.; Mazumder, A.; Zhao, H.; Sunder, S.; Burke Jr., T. R.; Schultz, R. J.; Pommier, Y. Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors. Antimicrob. Agents Chemother. 1997, 41, 385-393; (Pubitemid 27111035)
-
(1997)
Antimicrobial Agents and Chemotherapy
, vol.41
, Issue.2
, pp. 385-393
-
-
Neamati, N.1
Mazumder, A.2
Zhao, H.3
Sunder, S.4
Burke Jr., T.R.5
Schultz, R.J.6
Pommier, Y.7
-
10
-
-
0030045677
-
2-Sulfonyl-4-chloroanilino moiety: A potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones
-
(b) Artico, M.; Silvestri, R.; Massa, S.; Loi, A. G.; Corrias, S.; Piras, G.; La Colla, P. 2-Sulfonyl-4-chloroanilino moiety: A potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones. J. Med. Chem. 1996, 39, 522-530;
-
(1996)
J. Med. Chem.
, vol.39
, pp. 522-530
-
-
Artico, M.1
Silvestri, R.2
Massa, S.3
Loi, A.G.4
Corrias, S.5
Piras, G.6
La Colla, P.7
-
11
-
-
0027447592
-
Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase
-
(c) McMahon, J. B.; Gulakowsky, R. J.; Weislow, O. S.; Schultz, R. J.; Narayanan, V. L.; Clanton, D. J.; Pedemonte, R.; Wassmudt, F. W.; Buckheit, R. W.; Decker, W. D.; White, E. L.; Bader, J. P.; Boyd, M. R. Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 1993, 37, 754-760. (Pubitemid 23096874)
-
(1993)
Antimicrobial Agents and Chemotherapy
, vol.37
, Issue.4
, pp. 754-760
-
-
McMahon, J.B.1
Gulakowski, R.J.2
Weislow, O.S.3
Schultz, R.J.4
Narayanan, V.L.5
Clanton, D.J.6
Pedemonte, R.7
Wassmundt, F.W.8
Buckheit Jr., R.W.9
Decker, W.D.10
White, E.L.11
Bader, J.P.12
Boyd, M.R.13
-
12
-
-
0027195714
-
5-Chloro-3-(phenylsulfonyl)indole-2-carboxamide: A novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase
-
DOI 10.1021/jm00061a022
-
Williams, T. M.; Ciccarone, T. M.; Mac Tough, S. C.; Rooney, C. S.; Balani, S. K.; Condra, J. H.; Emini, E. A.; Goldman, M. E.; Greenlee, W. J.; Kauffman, L. R.; O'Brien, J. A.; Saradana, V. V.; Schleif, W. A.; Theohardes, A. D.; Anderson, P. S. 5-Chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase. J. Med. Chem. 1993, 36, 1291-1294. (Pubitemid 23159305)
-
(1993)
Journal of Medicinal Chemistry
, vol.36
, Issue.9
, pp. 1291-1294
-
-
Williams, T.M.1
Ciccarone, T.M.2
MacTough, S.C.3
Rooney, C.S.4
Balani, S.K.5
Condra, J.H.6
Emini, E.A.7
Goldman, M.E.8
Greenlee, W.J.9
Kauffman, L.R.10
O'Brien, J.A.11
Sardana, V.V.12
Schleif, W.A.13
Theoharides, A.D.14
Anderson, P.S.15
-
13
-
-
0141601826
-
Bismuth(III) trifluoromethanesulfonate: An efficient catalyst for the sulfonylation of arenas
-
Repichet, S.; Le Roux, C.; Hernandez, P.; Dubac, J.; Desmurs, J. R. Bismuth(III) trifluoromethanesulfonate: An efficient catalyst for the sulfonylation of arenes. J. Org. Chem. 1999, 64, 6479-6482.
-
(1999)
J. Org. Chem.
, vol.64
, pp. 6479-6482
-
-
Repichet, S.1
Le Roux, C.2
Hernandez, P.3
Dubac, J.4
Desmurs, J.R.5
-
14
-
-
34548147496
-
A general copper-catalyzed sulfonylation of arylboronic acids
-
(a) Kar, A.; Sayyed, I. A.; Lo, W. F.; Kaiser, H. M.; Beller, M.; Tse, M. F. A general copper-catalyzed sulfonylation of arylboronic acids. Org. Lett. 2007, 9, 3405-3408;
-
(2007)
Org. Lett.
, vol.9
, pp. 3405-3408
-
-
Kar, A.1
Sayyed, I.A.2
Lo, W.F.3
Kaiser, H.M.4
Beller, M.5
Tse, M.F.6
-
15
-
-
22244478987
-
Transformation of carbonates into sulfones at the benzylic position via palladium-catalyzed benzylic substitution
-
DOI 10.1021/ol0509787
-
(b) Kuwano, R.; Kondo, Y.; Shirahama, T. Transformation of carbonates into sulfones at the benzylic position via palladium-catalyzed benzylic substitution. Org. Lett. 2005, 7, 2973-2975; (Pubitemid 40992610)
-
(2005)
Organic Letters
, vol.7
, Issue.14
, pp. 2973-2975
-
-
Kuwano, R.1
Kondo, Y.2
Shirahama, T.3
-
16
-
-
0345887405
-
Unsymmetrical diaryl sulfones through palladium-catalyzed coupling of aryl iodides and arenesulfinates
-
(c) Cacchi, S.; Fabrizi, G.; Goggiamani, A.; Parisi, L. M. Unsymmetrical diaryl sulfones through palladium-catalyzed coupling of aryl iodides and arenesulfinates. Org. Lett. 2002, 4, 4719-4721.
-
(2002)
Org. Lett.
, vol.4
, pp. 4719-4721
-
-
Cacchi, S.1
Fabrizi, G.2
Goggiamani, A.3
Parisi, L.M.4
-
18
-
-
0002176008
-
-
C. H. Banford, C. F. H. Tipper (Eds.) ; Elsevier: New York
-
(b) Taylor, R. In: Comprehensive Chemical Kinetics; C. H. Banford, C. F. H. Tipper (Eds.); Elsevier: New York, 1972; pp. 77-83;
-
(1972)
Comprehensive Chemical Kinetics
, pp. 77-83
-
-
Taylor, R.1
-
20
-
-
0003070668
-
The Friedel-Crafts type methanesulfonylation of deactivated benzenes
-
(a) Ono, M.; Nakamura, Y.; Sato, S.; Itoh, I. The Friedel-Crafts type methanesulfonylation of deactivated benzenes. Chem. Lett. 1988, 17, 395-398;
-
(1988)
Chem. Lett.
, vol.17
, pp. 395-398
-
-
Ono, M.1
Nakamura, Y.2
Sato, S.3
Itoh, I.4
-
21
-
-
84982450115
-
Darstellung und Reaktionen von Arylsulfonsäure- trifluormethansulfonsa ̈ure-anhydriden
-
(b) Effenberger, F.; Huthmacher, K. Darstellung und Reaktionen von Arylsulfonsäure-trifluormethansulfonsa ̈ure-anhydriden. Chem. Ber. 1976, 109, 2315-2326.
-
(1976)
Chem. Ber.
, vol.109
, pp. 2315-2326
-
-
Effenberger, F.1
Huthmacher, K.2
-
23
-
-
47249141161
-
2Zn-mediated tertbutylhydroperoxide-promoted catalytic enantioselective Reformatsky reaction with aldehydes
-
2Zn-mediated, tertbutylhydroperoxide-promoted, catalytic enantioselective Reformatsky reaction with aldehydes. Chem. Commun. 2008, 3317-3318;
-
(2008)
Chem. Commun.
, pp. 3317-3318
-
-
Pier, G.C.1
Fides, B.2
Guiteras Capdevila, M.3
Alessandro, M.4
-
25
-
-
0028138739
-
New chiral ligand for optically active β-Hydroxy esters synthesis by enantioselective reformatsky reactions
-
DOI 10.1016/S0957-4166(00)86254-0
-
(c) Pini, D.; Mastantuono, A.; St. Jvadori, P. New chiral ligand for optically active β-hydroxy esters synthesis by enantioselective reformatsky reactions. Tetrahedron: Asymmetry 1994, 5, 1875-1876. (Pubitemid 24323224)
-
(1994)
Tetrahedron Asymmetry
, vol.5
, Issue.10
, pp. 1875-1876
-
-
Pini, D.1
Mastantuono, A.2
Salvadori, P.3
-
26
-
-
55249103938
-
Effective Pd-nanoparticle (PdNP)-catalyzed negishi coupling involving alkylzinc reagents at room temperature
-
Jing, L.; Yi, D.; Haibo, W.; Hua, Z.; Ganxiang, Y.; Bingbin, W.; Heng, Z.; Qiang, L.; Todd, B. M.; Zhen, Y.; Aiwen, L. Effective Pd-nanoparticle (PdNP)-catalyzed negishi coupling involving alkylzinc reagents at room temperature. Org. Lett. 2008, 10(13), 2661-2664.
-
(2008)
Org. Lett.
, vol.10
, Issue.13
, pp. 2661-2664
-
-
Jing, L.1
Yi, D.2
Haibo, W.3
Hua, Z.4
Ganxiang, Y.5
Bingbin, W.6
Heng, Z.7
Qiang, L.8
Todd, B.M.9
Zhen, Y.10
Aiwen, L.11
-
27
-
-
43449103645
-
A facile synthesis of N-sulfonyl and N-sulfinyl aldimines under barbier-type conditions
-
Renhua, F.; Dongming, P.; Fengqi, W.; Yang, Y.; Xiaoli, W. A facile synthesis of N-sulfonyl and N-sulfinyl aldimines under barbier-type conditions. J. Org. Chem. 2008, 73(9), 3623-3625.
-
(2008)
J. Org. Chem.
, vol.73
, Issue.9
, pp. 3623-3625
-
-
Renhua, F.1
Dongming, P.2
Fengqi, W.3
Yang, Y.4
Xiaoli, W.5
-
28
-
-
0031867235
-
Zinc-promoted regioselective friedel-crafts acylation of electron-rich arenes
-
Yadav, J. S.; Reddy, G. S.; Srinivas, D.; Meshram, H. M. Zinc-promoted regioselective friedel-crafts acylation of electron-rich arenes. Synth. Commun. 1998, 28, 2203.
-
(1998)
Synth. Commun.
, vol.28
, pp. 2203
-
-
Yadav, J.S.1
Reddy, G.S.2
Srinivas, D.3
Meshram, H.M.4
-
29
-
-
0032516323
-
Zinc-promoted simple and convenient synthesis of carbamates: An easy access for amino group protection
-
Yadav, J. S.; Reddy, G. S.; Srinivas, D.; Meshram, H. M. Zinc-promoted simple and convenient synthesis of carbamates: An easy access for amino group protection. Tetrahedron Lett. 1998, 39, 3259.
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 3259
-
-
Yadav, J.S.1
Reddy, G.S.2
Srinivas, D.3
Meshram, H.M.4
-
30
-
-
46149083034
-
Nickel-catalyzed cross-coupling reactions of benzylic zinc reagents with aromatic bromides, chlorides and tosylates
-
DOI 10.1039/b803072c
-
Schade, M. A.; Metzger, A.; Hug, S.; Knochel, P. Nickel-catalyzed cross-coupling reactions of benzylic zinc reagents with aromatic bromides, chlorides, and tosylates. Chem. Commun. 2008, 3046-3048. (Pubitemid 351904562)
-
(2008)
Chemical Communications
, Issue.26
, pp. 3046-3048
-
-
Schade, M.A.1
Metzger, A.2
Hug, S.3
Knochel, P.4
-
31
-
-
34249281669
-
Alternate method for the synthesis of N-alkyl/aralkyl-2-(α-hydroxy alkyl/aralkyl)benzimidazoles via regiospecific acetylation
-
DOI 10.1080/00397910701265556, PII 778960485
-
Dubey, P. K.; Prasada Reddy, P. V. V.; Srinivas, K. An alternate method for the synthesis of N-alkyl=aralkyl-2(a-hydroxyalkyl=aralkyl)benzimidazaoles via regiospecific acetylation. Synth. Commun. 2007, 37, 1675-1681. (Pubitemid 46808754)
-
(2007)
Synthetic Communications
, vol.37
, Issue.10
, pp. 1675-1681
-
-
Dubey, P.K.1
Reddy, P.V.V.P.2
Srinivas, K.3
-
32
-
-
36148953264
-
An expeditious "green" Michael addition of nitro methane to benzimidazole chalcones using TBAB as surface catalyst
-
Dubey, P. K.; Prasada Reddy, P. V. V.; Srinivas, K. An expeditious "Green" Michael addition of nitro methane to benzimidazole chalcones using TBAB as surface catalyst. Lett. Org. Chem. 2007, 4, 445-447.
-
(2007)
Lett. Org. Chem.
, vol.4
, pp. 445-447
-
-
Dubey, P.K.1
Prasada Reddy, P.V.V.2
Srinivas, K.3
-
33
-
-
36849087457
-
A facile tandem synthesis of α-benzylbenzimidazole acetonitriles
-
Dubey, P. K.; Prasada Reddy, P. V. V.; Srinivas, K. A facile tandem synthesis of α-benzylbenzimidazole acetonitriles. Arkivoc 2007, 15, 192-198.
-
(2007)
Arkivoc
, vol.15
, pp. 192-198
-
-
Dubey, P.K.1
Prasada Reddy, P.V.V.2
Srinivas, K.3
-
34
-
-
34548232708
-
Synthesis of 1-alkyl=aralkyl-2-(1-arylsulfonylalkyl)benzimidazoles under PTC conditions
-
Dubey, P. K.; Prasada Reddy, P. V. V.; Srinivas, K. Synthesis of 1-alkyl=aralkyl-2-(1-arylsulfonylalkyl)benzimidazoles under PTC conditions. Indian J. Chem. Sec. B 2007, 46, 488-491.
-
(2007)
Indian J. Chem. Sec. B
, vol.46
, pp. 488-491
-
-
Dubey, P.K.1
Prasada Reddy, P.V.V.2
Srinivas, K.3
|