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Volumn 9, Issue 2, 2011, Pages 94-101

Ethical and policy considerations in the application of pharmacogenomic testing for tardive dyskinesia: Case study of the dopamine D3 receptor

Author keywords

DRD3; Ethics; Pharmacogenomics; Prospective policy; Tardive dyskinesia

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; CHLORPROMAZINE; CLOZAPINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; FLUPHENAZINE; GLYCINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; SERINE; ZIPRASIDONE;

EID: 79955678926     PISSN: 18756921     EISSN: 18756913     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (70)
  • 1
    • 0020054615 scopus 로고
    • Tardive dyskinesia: Prevalence and risk fac-tors, 1959 to 1979
    • Kane JM, Smith JM. Tardive dyskinesia: prevalence and risk fac-tors, 1959 to 1979. Arch Gen Psychiatry 1982; 39(4): 473-481.
    • (1982) Arch Gen Psychiatry , vol.39 , Issue.4 , pp. 473-481
    • Kane, J.M.1    Smith, J.M.2
  • 2
    • 0019207526 scopus 로고
    • Changes in prevalence, severity, andrecovery in tardive dyskinesia with age
    • Smith JM, Baldessarini RJ. Changes in prevalence, severity, andrecovery in tardive dyskinesia with age. Arch Gen Psychiatry 1980; 37(12): 1368-1373.
    • (1980) Arch Gen Psychiatry , vol.37 , Issue.12 , pp. 1368-1373
    • Smith, J.M.1    Baldessarini, R.J.2
  • 3
    • 0343238211 scopus 로고    scopus 로고
    • Tardive dyskinesiaassociated with higher mortality in psychiatric patients: Results of ameta-analysis of seven independent studies
    • Ballesteros J, Gonzalez-Pinto A, Bulbena A. Tardive dyskinesiaassociated with higher mortality in psychiatric patients: results of ameta-analysis of seven independent studies. J Clin Psychopharma-col 2000; 20(2): 188-194.
    • (2000) J Clin Psychopharma-col , vol.20 , Issue.2 , pp. 188-194
    • Ballesteros, J.1    Gonzalez-Pinto, A.2    Bulbena, A.3
  • 4
    • 78651033868 scopus 로고
    • An unusual syndrome in the oral re-gion caused by administration of megaphen
    • Kulenkampff C, Tarnow G. An unusual syndrome in the oral re-gion caused by administration of megaphen. Nervenarzt 1956;27(4):178-80.
    • (1956) Nervenarzt , vol.27 , Issue.4 , pp. 178-180
    • Kulenkampff, C.1    Tarnow, G.2
  • 6
    • 84925558212 scopus 로고
    • 4 Cases of faciobucco-linguo-masticatory dyskinesis of prolonged development following treatment with neuroleptics
    • Sigwald J, Bouttier D, Raymondeaud C, et al. 4 Cases of faciobucco-linguo-masticatory dyskinesis of prolonged development following treatment with neuroleptics. Rev Neurol (Paris) 1959; 100: 751-55.
    • (1059) Rev Neurol (Paris) , vol.100 , pp. 751-755
    • Sigwald, J.1    Bouttier, D.2    Raymondeaud, C.3
  • 7
    • 0002217686 scopus 로고
    • Neurological symptoms in pharmacotherapy of psychoses
    • Faurbye A, Rasch PJ, Petersen PB, et al. Neurological symptoms in pharmacotherapy of psychoses. Acta Psychiatr Scand 1964; 40: 10-27.
    • (1964) Acta Psychiatr Scand , vol.40 , pp. 10-27
    • Faurbye, A.1    Rasch, P.J.2    Petersen, P.B.3
  • 8
    • 33646944093 scopus 로고    scopus 로고
    • Epidemiology of tardive dyskinesia: Is risk declining with modern antipsychotics?
    • Tarsy D, Baldessarini RJ. Epidemiology of tardive dyskinesia: is risk declining with modern antipsychotics? Mov Disord 2006; 21(5): 589-98.
    • (2006) Mov Disord , vol.21 , Issue.3 , pp. 589-598
    • Tarsy, D.1    Baldessarini, R.J.2
  • 9
    • 0016592484 scopus 로고
    • Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons
    • Seeman P, Lee T. Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 1975; 188(4194): 1217-9.
    • (1975) Science , vol.188 , Issue.4194 , pp. 1217-1219
    • Seeman, P.1    Lee, T.2
  • 10
    • 0033959580 scopus 로고    scopus 로고
    • Pharmacogenetics ofantipsychotic treatment: Lessons learned from clozapine
    • Masellis M, Basile VS, Ozdemir V, et al. Pharmacogenetics ofantipsychotic treatment: lessons learned from clozapine. Biol Psy-chiatry 2000; 47 (3): 252-266.
    • (2000) Biol Psy-chiatry , vol.47 , Issue.3 , pp. 252-266
    • Masellis, M.1    Basile, V.S.2    Ozdemir, V.3
  • 11
    • 1542373740 scopus 로고    scopus 로고
    • Lower risk for tardive dyskinesiaassociated with second-generation antipsychotics: A systematic re-view of 1-year studies
    • Correll CU, Leucht S, Kane JM. Lower risk for tardive dyskinesiaassociated with second-generation antipsychotics: a systematic re-view of 1-year studies. Am J Psychiatry 2004; 161(3): 414-425.
    • (2004) Am J Psychiatry , vol.161 , Issue.3 , pp. 414-425
    • Correll, C.U.1    Leucht, S.2    Kane, J.M.3
  • 12
    • 0032982269 scopus 로고    scopus 로고
    • Association of the MscIpolymorphism of the dopamine D3 receptor gene with tardive dy-skinesia in schizophrenia
    • Basile VS, Masellis M, Badri F, et al. Association of the MscIpolymorphism of the dopamine D3 receptor gene with tardive dy-skinesia in schizophrenia. Neuropsychopharmacology 1999; 21(1):17-27.
    • (1999) Neuropsychopharmacology , vol.21 , Issue.1 , pp. 17-27
    • Basile, V.S.1    Masellis, M.2    Badri, F.3
  • 13
    • 0030903368 scopus 로고    scopus 로고
    • Dopamine D3-receptorgene variant and susceptibility to tardive dyskinesia in schizo-phrenic patients
    • Steen VM, Lovlie R, MacEwan T, et al. Dopamine D3-receptorgene variant and susceptibility to tardive dyskinesia in schizo-phrenic patients. Mol Psychiatry 1997; 2(2): 139-145.
    • (1997) Mol Psychiatry , vol.2 , Issue.2 , pp. 139-145
    • Steen, V.M.1    Lovlie, R.2    Macewan, T.3
  • 14
    • 0035897696 scopus 로고    scopus 로고
    • ExecutiveSummary of The Third Report of The National Cholesterol Educaion Program (NCEP)
    • Expert Panel on Detection, Evaluation, and Treatment of HighBlood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of HighBlood Cholesterol in Adults (Adult Treatment Panel III). ExecutiveSummary of The Third Report of The National Cholesterol Education Program (NCEP). JAMA 2001; 285(19): 2486-2497.
    • (2001) JAMA , vol.285 , Issue.19 , pp. 2486-2497
  • 15
    • 0037126526 scopus 로고    scopus 로고
    • Third Report of the National Cholesterol Education Program (NCEP)
    • Expert Panel on Detection, Evaluation, and Treatment of HighBlood Cholesterol in Adults (Adult Treatment Panel III) final re-port
    • Expert Panel on Detection, Evaluation, and Treatment of HighBlood Cholesterol in Adults (Adult Treatment Panel III) final re-port. Third Report of the National Cholesterol Education Program (NCEP). Circulation 2002; 106(25): 3143-421.
    • (2002) Circulation , vol.106 , Issue.25 , pp. 3143-3421
  • 16
    • 33846975815 scopus 로고    scopus 로고
    • Metabolic considerations in the use of antipsy-chotic medications: A review of recent evidence
    • Newcomer JW. Metabolic considerations in the use of antipsy-chotic medications: a review of recent evidence. J Clin Psychiatry 2007; 68 (Suppl 1): 20-7.
    • (2007) J Clin Psychiatry , vol.68 , Issue.SUPPL 1 , pp. 20-27
    • Newcomer, J.W.1
  • 17
    • 0031808877 scopus 로고    scopus 로고
    • Excess mortality of mental disorder
    • Harris EC, Barraclough B. Excess mortality of mental disorder. BrJ Psychiatry 1998; 173: 11-53.
    • (1998) BrJ Psychiatry , vol.173 , pp. 11-53
    • Harris, E.C.1    Barraclough, B.2
  • 18
    • 0345920900 scopus 로고    scopus 로고
    • Nuffield Council on Bioethics, London: Nuffield Council on Bioethics
    • Nuffield Council on Bioethics. Pharmacogenetics: Ethical Issues. London: Nuffield Council on Bioethics. 2003.
    • (2003) Pharmacogenetics: Ethical Issues
  • 19
    • 0033011674 scopus 로고    scopus 로고
    • The ethical use of evidence in biomedicine
    • Pellegrino ED. The ethical use of evidence in biomedicine. EvalHealth Prof 1999; 22(1): 33-43.
    • (1999) EvalHealth Prof , vol.22 , Issue.1 , pp. 33-43
    • Pellegrino, E.D.1
  • 20
    • 77953805956 scopus 로고    scopus 로고
    • Clinical and ethical con-siderations in pharmacogenetic testing: Views of physicians in 3early adopting departments of psychiatry
    • Hoop JG, Lapid MI, Paulson RM, et al. Clinical and ethical con-siderations in pharmacogenetic testing: views of physicians in 3early adopting departments of psychiatry. J Clin Psychiatry 2010;71(6): 745-753.
    • (2010) J Clin Psychiatry , vol.71 , Issue.6 , pp. 745-753
    • Hoop, J.G.1    Lapid, M.I.2    Paulson, R.M.3
  • 21
    • 0024957812 scopus 로고
    • Possible involvement of free radicals in neuro-leptic-induced movement disorders. Evidence from treatment oftardive dyskinesia with vitamin
    • Cadet JL, Lohr JB. Possible involvement of free radicals in neuro-leptic-induced movement disorders. Evidence from treatment oftardive dyskinesia with vitamin E. Ann N Y Acad Sci 1989; 570:176-185.
    • (1989) E. Ann N Y Acad Sci , vol.570 , pp. 176-185
    • Cadet, J.L.1    Lohr, J.B.2
  • 22
    • 16544368420 scopus 로고    scopus 로고
    • Clinical implications ofpharmacogenomics for tardive dyskinesia
    • Muller DJ, Shinkai T, De Luca V, et al. Clinical implications ofpharmacogenomics for tardive dyskinesia. Pharmacogenomics J 2004; 4(2): 77-87.
    • (2004) Pharmacogenomics J , vol.4 , Issue.2 , pp. 77-87
    • Muller, D.J.1    Shinkai, T.2    De Luca, V.3
  • 23
    • 33144468024 scopus 로고    scopus 로고
    • Pharmacogenetics for off-patent antipsychotics: Reframing the risk for tardive dyskinesia andaccess to essential medicines
    • Ozdemir V, Aklillu E, Mee S, et al. Pharmacogenetics for off-patent antipsychotics: reframing the risk for tardive dyskinesia andaccess to essential medicines. Expert Opin Pharmacother 2006; 7(2): 119-33.
    • (2006) Expert Opin Pharmacother , vol.7 , Issue.2 , pp. 119-133
    • Ozdemir, V.1    Aklillu, E.2    Mee, S.3
  • 24
    • 0026708797 scopus 로고
    • The Nithsdale schizo-phrenia surveys. IX: Akathisia, parkinsonism, tardive dyskinesiaand plasma neuroleptic levels
    • McCreadie RG, Robertson LJ, Wiles DH. The Nithsdale schizo-phrenia surveys. IX: Akathisia, parkinsonism, tardive dyskinesiaand plasma neuroleptic levels. Br J Psychiatry 1992; 160: 793-9.
    • (1992) Br J Psychiatry , vol.160 , pp. 793-799
    • McCreadie, R.G.1    Robertson, L.J.2    Wiles, D.H.3
  • 26
    • 0027264874 scopus 로고
    • Predicting the long-termrisk of tardive dyskinesia in outpatients maintained on neurolepticmedications
    • Glazer WM, Morgenstern H, Doucette JT. Predicting the long-termrisk of tardive dyskinesia in outpatients maintained on neurolepticmedications. J Clin Psychiatry 1993; 54(4): 133-9.
    • (1993) J Clin Psychiatry , vol.54 , Issue.4 , pp. 133-139
    • Glazer, W.M.1    Morgenstern, H.2    Doucette, J.T.3
  • 28
    • 0021200941 scopus 로고
    • Tardive dyskinesia--prevalence and subtypes at Valkenberg Hospital, Cape Town
    • Holden TJ, Sandler R, Myslobodsky M. Tardive dyskinesia--prevalence and subtypes at Valkenberg Hospital, Cape Town. S AfrMed J 1984; 66(4): 132-4.
    • (1984) S AfrMed J , vol.66 , Issue.4 , pp. 132-134
    • Holden, T.J.1    Sandler, R.2    Myslobodsky, M.3
  • 29
    • 0022600929 scopus 로고
    • Integrating incidenceand prevalence of tardive dyskinesia
    • Kane JM, Woerner M, Borenstein M, et al. Integrating incidenceand prevalence of tardive dyskinesia. Psychopharmacol Bull 1986;22(1): 254-8.
    • (1986) Psychopharmacol Bull , vol.22 , Issue.1 , pp. 254-258
    • Kane, J.M.1    Woerner, M.2    Borenstein, M.3
  • 30
    • 0027244076 scopus 로고
    • Identifying risk factors for tardivedyskinesia among long-term outpatients maintained with neurolep-tic medications. Results of the Yale Tardive Dyskinesia Study
    • Morgenstern H, Glazer WM. Identifying risk factors for tardivedyskinesia among long-term outpatients maintained with neurolep-tic medications. Results of the Yale Tardive Dyskinesia Study. Arch Gen Psychiatry 1993; 50(9): 723-733.
    • (1993) Arch Gen Psychiatry , vol.50 , Issue.9 , pp. 723-733
    • Morgenstern, H.1    Glazer, W.M.2
  • 31
    • 0030854215 scopus 로고    scopus 로고
    • Tardive dyskinesia andethnicity: Review of the literature
    • Swartz JR, Burgoyne K, Smith M, et al. Tardive dyskinesia andethnicity: review of the literature. Ann Clin Psychiatry 1997; 9(1):53-9.
    • (1997) Ann Clin Psychiatry , vol.9 , Issue.1 , pp. 53-59
    • Swartz, J.R.1    Burgoyne, K.2    Smith, M.3
  • 32
    • 0031790237 scopus 로고    scopus 로고
    • Prospective study oftardive dyskinesia in the elderly: Rates and risk factors
    • Woerner MG, Alvir JM, Saltz BL, et al. Prospective study oftardive dyskinesia in the elderly: rates and risk factors. Am JPsychiatry 1998; 155(11): 1521-8.
    • (1998) Am JPsychiatry , vol.155 , Issue.11 , pp. 1521-1528
    • Woerner, M.G.1    Alvir, J.M.2    Saltz, B.L.3
  • 33
    • 8744231989 scopus 로고    scopus 로고
    • Ethnicity and the courseof tardive dyskinesia in outpatients presenting to the motor disor-ders clinic at the Maryland psychiatric research center
    • Wonodi I, Adami HM, Cassady SL, et al. Ethnicity and the courseof tardive dyskinesia in outpatients presenting to the motor disor-ders clinic at the Maryland psychiatric research center. J Clin Psy-chopharmacol 2004; 24(6): 592-8.
    • (2004) J Clin Psy-chopharmacol , vol.24 , Issue.6 , pp. 592-598
    • Wonodi, I.1    Adami, H.M.2    Cassady, S.L.3
  • 34
    • 0029743108 scopus 로고    scopus 로고
    • Relationship of ethnicityand gender to schizophrenia and pharmacology of neuroleptics
    • Jeste DV, Lindamer LA, Evans J, et al. Relationship of ethnicityand gender to schizophrenia and pharmacology of neuroleptics. Psychopharmacol Bull 1996; 32(2): 243-251.
    • (1996) Psychopharmacol Bull , vol.32 , Issue.2 , pp. 243-251
    • Jeste, D.V.1    Lindamer, L.A.2    Evans, J.3
  • 35
    • 0036283004 scopus 로고    scopus 로고
    • Pharmacogenetics oftardive dyskinesia: Combined analysis of 780 patients supports as-sociation with dopamine D3 receptor gene Ser9Gly polymorphism
    • Lerer B, Segman RH, Fangerau H, et al. Pharmacogenetics oftardive dyskinesia: combined analysis of 780 patients supports as-sociation with dopamine D3 receptor gene Ser9Gly polymorphism. Neuropsychopharmacology 2002; 27(1): 105-119.
    • (2002) Neuropsychopharmacology , vol.27 , Issue.1 , pp. 105-119
    • Lerer, B.1    Segman, R.H.2    Fangerau, H.3
  • 36
    • 33645851672 scopus 로고    scopus 로고
    • Antipsychotic-induced tardivedyskinesia and the Ser9Gly polymorphism in the DRD3 gene: Ameta analysis
    • Bakker PR, van Harten PN, van OJ. Antipsychotic-induced tardivedyskinesia and the Ser9Gly polymorphism in the DRD3 gene: ameta analysis. Schizophr Res 2006; 83(2-3): 185-192.
    • (2006) Schizophr Res , vol.83 , Issue.2-3 , pp. 185-192
    • Bakker, P.R.1    van Harten, P.N.2    van, O.J.3
  • 37
    • 73949158783 scopus 로고    scopus 로고
    • The DRD3 rs6280 polymor-phism and prevalence of tardive dyskinesia: A meta-analysis
    • Tsai HT, North KE, West SL, et al. The DRD3 rs6280 polymor-phism and prevalence of tardive dyskinesia: A meta-analysis. Am JMed Genet B Neuropsychiatr Genet 2010; 153B(1): 57-66.
    • (2010) Am JMed Genet B Neuropsychiatr Genet , vol.153 B , Issue.1 , pp. 57-66
    • Tsai, H.T.1    North, K.E.2    West, S.L.3
  • 38
    • 63149117860 scopus 로고    scopus 로고
    • Tardive dy-skinesia and DRD3, HTR2A and HTR2C gene polymorphisms inRussian psychiatric inpatients from Siberia
    • Al Hadithy AF, Ivanova SA, Pechlivanoglou P, et al. Tardive dy-skinesia and DRD3, HTR2A and HTR2C gene polymorphisms inRussian psychiatric inpatients from Siberia. Prog Neuropsycho-pharmacol Biol Psychiatry 2009; 33(3): 475-481.
    • (2009) Prog Neuropsycho-pharmacol Biol Psychiatry , vol.33 , Issue.3 , pp. 475-481
    • Al Hadithy, A.F.1    Ivanova, S.A.2    Pechlivanoglou, P.3
  • 40
    • 44949207490 scopus 로고    scopus 로고
    • Pharmacogenomics, ethics, and public policy
    • Peterson-Iyer K. Pharmacogenomics, ethics, and public policy.Kennedy Inst Ethics J 2008; 18(1): 35-56.
    • (2008) Kennedy Inst Ethics J , vol.18 , Issue.1 , pp. 35-56
    • Peterson-Iyer, K.1
  • 41
    • 77953379592 scopus 로고    scopus 로고
    • Pharmacogenomics: Reflections on the old and newsocial, ethical, and policy issues in post-genomics medicine
    • Basel: Karger
    • Ozdemir V. Pharmacogenomics: Reflections on the old and newsocial, ethical, and policy issues in post-genomics medicine. In:Pharmacogenomics in Psychiatry. Basel: Karger 2010; pp. 12-29.
    • (2010) Pharmacogenomics In Psychiatry , pp. 12-29
    • Ozdemir, V.1
  • 42
    • 77951224980 scopus 로고    scopus 로고
    • Schizophrenia, mental capacity, and rational suicide
    • Hewitt J. Schizophrenia, mental capacity, and rational suicide. Theor Med Bioeth 2010; 31(1): 63-77.
    • (2010) Theor Med Bioeth , vol.31 , Issue.1 , pp. 63-77
    • Hewitt, J.1
  • 43
    • 25444469935 scopus 로고    scopus 로고
    • Atypical antipsychotics: Considerations for Medicaidcoverage
    • Surles RC. Atypical antipsychotics: considerations for Medicaidcoverage. Am J Manag Care 2005; 11(Suppl 8): S248-53.
    • (2005) Am J Manag Care , vol.11 , Issue.SUPPL 8
    • Surles, R.C.1
  • 46
    • 13544266547 scopus 로고    scopus 로고
    • Stored tissue samples: Throughthe confidentiality maze
    • Joly Y, Knoppers BM, Nguyen MT. Stored tissue samples: throughthe confidentiality maze. Pharmacogenomics J 2005; 5(1): 2-5.
    • (2005) Pharmacogenomics J , vol.5 , Issue.1 , pp. 2-5
    • Joly, Y.1    Knoppers, B.M.2    Nguyen, M.T.3
  • 47
    • 33749252978 scopus 로고    scopus 로고
    • World Health Organization, Available from, [Ac-cessed February 28, 2011]
    • World Health Organization. WHO Model Lists of Essential Medicines. 2009. Available from: http://www.who.int/selection_medicines/committees/expert/17/sixteenth_adult_list_en.pdf [Ac-cessed February 28, 2011].
    • (2009) WHO Model Lists of Essential Medicines
  • 48
    • 43749099945 scopus 로고    scopus 로고
    • Human genomicvariation studies and pharmacogenomics are critical for globalhealth
    • Suarez-Kurtz G, Eds. Georgetown, TX: Landes Bioscience
    • Seguin B, Essajee S, Jimenez-Sanchez G, et al. Human genomicvariation studies and pharmacogenomics are critical for globalhealth. In: Pharmacogenomics in Admixed Populations. Suarez-Kurtz G, Eds. Georgetown, TX: Landes Bioscience 2007; pp. 198-207.
    • (2007) Pharmacogenomics In Admixed Populations , pp. 198-207
    • Seguin, B.1    Essajee, S.2    Jimenez-Sanchez, G.3
  • 49
    • 14344258388 scopus 로고    scopus 로고
    • Pharmacogenetics and geographical ancestry:Implications for drug development and global health
    • Daar AS, Singer PA. Pharmacogenetics and geographical ancestry:implications for drug development and global health. Nat RevGenet 2005; 6(3): 241-6.
    • (2005) Nat RevGenet , vol.6 , Issue.3 , pp. 241-246
    • Daar, A.S.1    Singer, P.A.2
  • 50
    • 31344469000 scopus 로고    scopus 로고
    • Coronary artery disease in minority racial andethnic groups in the United States
    • Ferdinand KC. Coronary artery disease in minority racial andethnic groups in the United States. Am J Cardiol 2006; 97(2A):12A-9A.
    • (2006) Am J Cardiol , vol.97 , Issue.2 A
    • Ferdinand, K.C.1
  • 51
    • 8744315598 scopus 로고    scopus 로고
    • The concept of essential medicines: Lessons for richcountries
    • Hogerzeil HV. The concept of essential medicines: lessons for richcountries. BMJ 2004; 329(7475): 1169-72.
    • (2004) BMJ , vol.329 , Issue.7475 , pp. 1169-1172
    • Hogerzeil, H.V.1
  • 52
    • 0034104341 scopus 로고    scopus 로고
    • Update on legal issues associated with tardive dyski-nesia
    • Slovenko R. Update on legal issues associated with tardive dyski-nesia. J Clin Psychiatry 2000; 61(Suppl 4): 45-57.
    • (2000) J Clin Psychiatry , vol.61 , Issue.4 SUPPL , pp. 45-57
    • Slovenko, R.1
  • 53
    • 47549102444 scopus 로고    scopus 로고
    • The ethics of characterizingdifference: Guiding principles on using racial categories in humangenetics
    • Lee SS, Mountain J, Koenig B, et al. The ethics of characterizingdifference: guiding principles on using racial categories in humangenetics. Genome Biol 2008; 9(7): 404.
    • (2008) Genome Biol , vol.9 , Issue.7 , pp. 404
    • Lee, S.S.1    Mountain, J.2    Koenig, B.3
  • 54
    • 58449133694 scopus 로고    scopus 로고
    • Medicine. Racing forward: The Genomics andPersonalized Medicine Act
    • Lee SS, Mudaliar A. Medicine. Racing forward: the Genomics andPersonalized Medicine Act. Science 2009; 323(5912): 342.
    • (2009) Science , vol.323 , Issue.5912 , pp. 342
    • Lee, S.S.1    Mudaliar, A.2
  • 55
    • 77956257911 scopus 로고    scopus 로고
    • The emergence of transla-tional epidemiology: From scientific discovery to population healthimpact
    • Khoury MJ, Gwinn M, Ioannidis JP. The emergence of transla-tional epidemiology: from scientific discovery to population healthimpact. Am J Epidemiol 2010; 172(5): 517-524.
    • (2010) Am J Epidemiol , vol.172 , Issue.5 , pp. 517-524
    • Khoury, M.J.1    Gwinn, M.2    Ioannidis, J.P.3
  • 56
    • 0035969937 scopus 로고    scopus 로고
    • Pharmacogenetic assess-ment of antipsychotic-induced movement disorders: Contribution ofthe dopamine D3 receptor and cytochrome P450 1A2 genes
    • Ozdemir V, Basile VS, Masellis M, et al. Pharmacogenetic assess-ment of antipsychotic-induced movement disorders: contribution ofthe dopamine D3 receptor and cytochrome P450 1A2 genes. J Bio-chem Biophys Methods 2001; 47(1-2): 151-7.
    • (2001) J Bio-chem Biophys Methods , vol.47 , Issue.1-2 , pp. 151-157
    • Ozdemir, V.1    Basile, V.S.2    Masellis, M.3
  • 57
    • 0034785813 scopus 로고    scopus 로고
    • Genetic dissection ofatypical antipsychotic-induced weight gain: Novel preliminary dataon the pharmacogenetic puzzle
    • Basile VS, Masellis M, McIntyre RS, et al. Genetic dissection ofatypical antipsychotic-induced weight gain: novel preliminary dataon the pharmacogenetic puzzle. J Clin Psychiatry 2001; 62(Suppl 23): 45-66.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL 23 , pp. 45-66
    • Basile, V.S.1    Masellis, M.2    McIntyre, R.S.3
  • 58
    • 0037202751 scopus 로고    scopus 로고
    • 759C/T genetic variation of5HT(2C) receptor and clozapine-induced weight gain
    • Basile VS, Masellis M, De L,V, et al. 759C/T genetic variation of5HT(2C) receptor and clozapine-induced weight gain. Lancet 2002;360 (9347): 1790-1.
    • (2002) Lancet , vol.360 , Issue.9347 , pp. 1790-1791
    • Basile, V.S.1    Masellis, M.2    De, L.V.3
  • 59
    • 79955683230 scopus 로고    scopus 로고
    • The ethics of personalised healthcare in a consumer age
    • Nuffield Council on Bioethics. Medical profiling and online medi-cine, Lon-don: Nuffield Council on Bioethics
    • Nuffield Council on Bioethics. Medical profiling and online medi-cine: The ethics of personalised healthcare in a consumer age. Lon-don: Nuffield Council on Bioethics. 2010.
    • (2010)
  • 60
    • 33846840696 scopus 로고    scopus 로고
    • Social and ethical aspects of pharmacogenomics in psy-chiatry
    • Rose N. Social and ethical aspects of pharmacogenomics in psy-chiatry. Psychiatry 2007; 6(2): 80-2.
    • (2007) Psychiatry , vol.6 , Issue.2 , pp. 80-82
    • Rose, N.1
  • 62
    • 41149173732 scopus 로고    scopus 로고
    • Why should genomic medicine becomemore evidence-based?
    • Khoury MJ, Bradley LA. Why should genomic medicine becomemore evidence-based? Genomic Med 2007; 1(3-4): 91-3.
    • (2007) Genomic Med , vol.1 , Issue.3-4 , pp. 91-93
    • Khoury, M.J.1    Bradley, L.A.2
  • 63
    • 0033046439 scopus 로고    scopus 로고
    • Genotypic associa-tion between the dopamine D3 receptor and tardive dyskinesia inchronic schizophrenia
    • Segman R, Neeman T, Heresco-Levy U, et al. Genotypic associa-tion between the dopamine D3 receptor and tardive dyskinesia inchronic schizophrenia. Mol Psychiatry 1999; 4(3): 247-253.
    • (1999) Mol Psychiatry , vol.4 , Issue.3 , pp. 247-253
    • Segman, R.1    Neeman, T.2    Heresco-Levy, U.3
  • 64
    • 0034092396 scopus 로고    scopus 로고
    • Homozygosity for theGly-9 variant of the dopamine D3 receptor and risk for tardive dy-skinesia in schizophrenic patients
    • Lovlie R, Daly AK, Blennerhassett R, et al. Homozygosity for theGly-9 variant of the dopamine D3 receptor and risk for tardive dy-skinesia in schizophrenic patients. Int J Neuropsychopharmacol 2000; 3(1): 61-65.
    • (2000) Int J Neuropsychopharmacol , vol.3 , Issue.1 , pp. 61-65
    • Lovlie, R.1    Daly, A.K.2    Blennerhassett, R.3
  • 65
    • 0034894948 scopus 로고    scopus 로고
    • Association between theSer9Gly polymorphism of the dopamine D3 receptor gene andtardive dyskinesia in Chinese schizophrenic patients
    • Liao DL, Yeh YC, Chen HM, et al. Association between theSer9Gly polymorphism of the dopamine D3 receptor gene andtardive dyskinesia in Chinese schizophrenic patients. Neuropsy-chobiology 2001; 44(2): 95-8.
    • (2001) Neuropsy-chobiology , vol.44 , Issue.2 , pp. 95-98
    • Liao, D.L.1    Yeh, Y.C.2    Chen, H.M.3
  • 66
    • 0036342556 scopus 로고    scopus 로고
    • Association of the Ser9Gly poly-morphism in the dopamine D3 receptor gene with tardive dyskine-sia in Korean schizophrenics
    • Woo SI, Kim JW, Rha E, et al. Association of the Ser9Gly poly-morphism in the dopamine D3 receptor gene with tardive dyskine-sia in Korean schizophrenics. Psychiatry Clin Neurosci 2002;56(4): 469-474.
    • (2002) Psychiatry Clin Neurosci , vol.56 , Issue.4 , pp. 469-474
    • Woo, S.I.1    Kim, J.W.2    Rha, E.3
  • 67
    • 0041825283 scopus 로고    scopus 로고
    • Polymorphisms of dopaminereceptors and tardive dyskinesia among Chinese patients withschizophrenia
    • Chong SA, Tan EC, Tan CH, et al. Polymorphisms of dopaminereceptors and tardive dyskinesia among Chinese patients withschizophrenia. Am J Med Genet B Neuropsychiatr Genet 2003;116B(1): 51-54.
    • (2003) Am J Med Genet B Neuropsychiatr Genet , vol.116 B , Issue.1 , pp. 51-54
    • Chong, S.A.1    Tan, E.C.2    Tan, C.H.3
  • 68
    • 0041331543 scopus 로고    scopus 로고
    • Interaction between polymor-phisms of the dopamine D3 receptor and manganese superoxidedismutase genes in susceptibility to tardive dyskinesia
    • Zhang ZJ, Zhang XB, Hou G, et al. Interaction between polymor-phisms of the dopamine D3 receptor and manganese superoxidedismutase genes in susceptibility to tardive dyskinesia. PsychiatrGenet 2003; 13(3): 187-192.
    • (2003) Psychiatr Genet , vol.13 , Issue.3 , pp. 187-192
    • Zhang, Z.J.1    Zhang, X.B.2    Hou, G.3
  • 69
    • 25444490459 scopus 로고    scopus 로고
    • Polymorphic variations inGSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 andD3 receptors and their association with tardive dyskinesia in severemental illness
    • de Leon J, Susce MT, Pan RM, et al. Polymorphic variations inGSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 andD3 receptors and their association with tardive dyskinesia in severemental illness. J Clin Psychopharmacol 2005; 25(5): 448-456.
    • (2005) J Clin Psychopharmacol , vol.25 , Issue.5 , pp. 448-456
    • de Leon, J.1    Susce, M.T.2    Pan, R.M.3
  • 70
    • 63149158063 scopus 로고    scopus 로고
    • Association of the do-pamine D3 receptor Ser9Gly and of the serotonin 2C receptor genepolymorphisms with tardive dyskinesia in Greeks with chronicschizophrenic disorder
    • Rizos EN, Siafakas N, Katsantoni E, et al. Association of the do-pamine D3 receptor Ser9Gly and of the serotonin 2C receptor genepolymorphisms with tardive dyskinesia in Greeks with chronicschizophrenic disorder. Psychiatr Genet 2009; 19(2): 106-107.
    • (2009) Psychiatr Genet , vol.19 , Issue.2 , pp. 106-107
    • Rizos, E.N.1    Siafakas, N.2    Katsantoni, E.3


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