Serine 204 phosphorylation and O - GlcNAC interplay of IGFBP-6 as therapeutic indicator to regulate IGF-II functions in viral mediated hepatocellular carcinoma

Virology Journal

Volumn 8, Issue , 2011, Pages

  Ahmad, Waqar ^a   Shabbiri, Khadija ^b   Ijaz, Bushra ^a   Asad, Sultan ^a   Nazar, Noreen ^b   Nazar, Shazia ^b   Fouzia, Kiran ^b   Kausar, Humera ^a   Gull, Sana ^a   Sarwar, Muhammad T ^a   Shahid, Imaran ^a   Hassan, Sajida ^a  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

^b GC UNIVERSITY   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 6; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINE; SERINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CANCER GROWTH; CONTROLLED STUDY; ENZYME BINDING; ENZYME MODIFICATION; ENZYME PHOSPHORYLATION; HEPATITIS B; HEPATITIS C; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; NERVE CELL NETWORK; NONHUMAN; PREDICTION; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; RAT; GLYCOSYLATION; HEPATITIS B VIRUS; HEPATITIS C VIRUS; METABOLISM; MOLECULAR GENETICS; PATHOGENICITY; PHOSPHORYLATION; PROTEIN BINDING; SEQUENCE ALIGNMENT; VIROLOGY;

HEPATITIS C VIRUS;

ACETYLGLUCOSAMINE; AMINO ACID SEQUENCE; CARCINOMA, HEPATOCELLULAR; GLYCOSYLATION; HEPACIVIRUS; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 6; INSULIN-LIKE GROWTH FACTOR II; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; SEQUENCE ALIGNMENT; SERINE;

EID: 79955675416     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-8-208     Document Type: Article

References (57)

1. Estimating the world cancer burden: Globocan 2000. DM Parkin F Bray J Ferlay P Pisani, Int J Cancer 2001 94 153 156 10.1002/ijc.1440 11668491 (Pubitemid 32911406)
2. Hepatocellular Carcinoma: Overcoming Challenges in Disease Management. RG Gish, Clin Gastroenterol Hepatol 2006 4 252 261 10.1016/j.cgh.2006.01.001 16527686 (Pubitemid 43343879)
3. Obesity and cancer risk: the role of the insulin-IGF axis. AG Renehan J Frystyk A Flyvbjerg, Trends Endocrinol Metab 2006 17 328 336 10.1016/j.tem.2006.08.006 16956771 (Pubitemid 44397568)
4. Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development. W Ruan DL Kleinberg, Endocrinology 1999 140 5075 5081 10.1210/en.140.11.5075 10537134
5. Insulin-like growth factor II (IGF-II). SD O'Dell IN Day, Int J Biochem Cell Biol 1998 30 767 771 10.1016/S1357-2725(98)00048-X 9722981 (Pubitemid 28352738)
6. Expression of IGF receptors and its ligands in bovine oocytes and preimplantation embryos. LM Wang HL Feng YZh Ma M Cang HJ Li Zh Yan P Zhou JX Wen S Bou DJ Liu, Anim Reprod Sci 2009 114 99 108 10.1016/j.anireprosci.2008.09. 019 19013732
7. Role of the insulin-like growth factor family in cancer development and progression. H Yu T Rohan, J Natl Cancer Inst 2000 92 1472 1489 10.1093/jnci/92.18.1472 10995803
8. Insulin-like growth factor-related genes, receptors, and binding proteins in cultured human retinal pigment epithelial cells. H Takagi N Yoshimura H Tanihara Y Honda, Invest Ophthalmol Vis Sci 1994 35 916 923 7510274 (Pubitemid 24079822)
9. The type II insulin-like growth factor receptor is internalized and recycles in the absence of ligand. Y Oka MP Czech, J Biol Chem 1986 261 9090 9093 3013875 (Pubitemid 17218174)
10. Single transmembrane domain insulin-like growth factor-II/mannose-6- phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway. C Hawkes JH Jhamandas KH Harris W Fu RG MacDonald S Kar, J Neurosci 2006 26 585 596 10.1523/JNEUROSCI.2730-05.2006 16407557 (Pubitemid 43237124)
11. Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta. GL King AD Goodman S Buzney A Moses CR Kahn, J Clin Invest 1985 75 1028 1036 10.1172/JCI111764 2984251 (Pubitemid 15115273)
12. The insulin-like growth factor-II/mannose-6-phosphate receptor is present in fetal bovine tissues throughout gestation. M Pfuender H Sauerwein B Funk U Kessler B Barenton HP Schwarz A Hoeflich W Kiess, Domest Anim Endocrinol 1995 12 317 324 10.1016/0739-7240(95)00028-D 8575164
13. Simultaneous over-expression of insulin-like growth factor-II (IGF II) and IGF-II receptor (IGF-II R) genes in human primary cancer-implication of autocrine and paracrine mechanism in autonomous growth of hepatic cancer. X Zhou J Gu Y Cheng H Jiang L Qian G Xu S David, Chin J Cancer Res 1992 1 10
14. The IGF axis and hepatocarcinogenesis. JG Scharf F Dombrowski G Ramadori, Mol Pathol 2001 54 138 144 10.1136/mp.54.3.138 11376124 (Pubitemid 32539603)
15. Role of constitutively activated and insulin-like growth factor-stimulated ERK1/2 signaling in human hepatoma cell proliferation and apoptosis: evidence for heterogeneity of tumor cell lines. C Alexia M Lasfer A Groyer, Ann N Y Acad Sci 2004 1030 219 229 10.1196/annals.1329.028 15659801 (Pubitemid 40378917)
16. Recent developments in the first detection of hepatocellular carcinoma. JB Lopez, Clin Biochem Rev 2005 26 65 79 16450014
17. Immunobiology and pathogenesis of viral hepatitis. LG Guidotti FV Chisari, Annu Rev Pathol 2006 1 23 61 10.1146/annurev.pathol.1.110304.100230 18039107
18. IGFBP-6 five years on; not so 'forgotten'? LA Bach, Growth Horm IGF Res 2005 15 185 192 10.1016/j.ghir.2005.04.001 15914054 (Pubitemid 40754120)
19. Identification of O-glycosylation sites and partial characterization of carbohydrate structure and disulfide linkages of human insulin-like growth factor binding protein 6. GM Neumann JA Marinaro LA Bach, Biochemistry 1998 37 6572 6585 10.1021/bi972894e 9572875 (Pubitemid 28213678)
20. O-glycosylation of insulin-like growth factor (IGF) binding protein-6 maintains high IGF-II binding affinity by decreasing binding to glycosaminoglycans and susceptibility to proteolysis. JA Marinaro GM Neumann VC Russo KS Leeding LA Bach, Eur J Biochem 2000 267 5378 5386 10951195
21. C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II. SJ Headey DW Keizer S Yao G Brasier P Kantharidis LA Bach RS Norton, Mol Endocrinol 2004 18 2740 2750 10.1210/me.2004-0248 15308688 (Pubitemid 39482062)
22. Cellular actions of the insulin-like growth factor binding proteins. SM Firth RC Baxter, Endocr Rev 2002 23 824 854 10.1210/er.2001-0033 12466191 (Pubitemid 35454590)
23. Changes in insulin-like growth factor binding protein (IGFBP) isoforms during bovine follicular development. B Nicholas RK Scougall DG Armstrong R Webb, Reproduction 2002 124 439 446 10.1530/rep.0.1240439 12201817 (Pubitemid 35023576)
24. Insulin-like growth factor binding proteins and their role in controlling IGF actions. DR Clemmons, Cytokine Growth Factor Rev 1997 8 45 62 10.1016/S1359-6101(96)00053-6 9174662 (Pubitemid 27214688)
25. IGF-II promoter methylation and ovarian cancer prognosis. AC Beeghly D Katsaros AL Wiley IA Rigault de la Longrais AT Prescott H Chen M Puopolo TJ Rutherford H Yu, J Cancer Res Clin Oncol 2007 133 713 723 10.1007/s00432-007- 0211-3 17569086 (Pubitemid 47319238)
26. The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003. B Boeckmann A Bairoch R Apweiler MC Blatter A Estreicher E Gasteiger MJ Martin K Michoud C O'Donovan I Phan S Pilbout M Schneider, Nucleic Acids Res 2003 31 365 370 10.1093/nar/gkg095 12520024 (Pubitemid 36157284)
27. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. SF AltschuL TL Madden AA Schaffer J Zhang Z Zhang W Miller DJ Lipman, Nucleic Acids Res 1997 25 3389 3402 10.1093/nar/25.17.3389 9254694 (Pubitemid 27359211)
28. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. JD Thompson DJ Higgins TJ Gibson, Nucleic Acids Res 1994 22 4673 46780 10.1093/nar/22.22.4673 7984417
29. Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. N Blom T Sicheritz-Ponten R Gupta S Gammeltoft S Brunk, Proteomics 2004 4 1633 1649 10.1002/pmic.200300771 15174133 (Pubitemid 38738322)
30. Intrinsic disorder and protein phosphorylation. LM Iakoucheva P Radivojac CJ Brown TR O'Connor JG Sikes Z Obradovic AK Dunker, Nucleic Acids Research 2004 32 1037 1049 10.1093/nar/gkh253 14960716
31. Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. N Blom T Sicheritz-Ponten R Gupta S Gammeltoft S Brunk, Proteomics 2004 4 1633 1649 10.1002/pmic.200300771 15174133 (Pubitemid 38738322)
32. KinasePhos: a web tool for identifying protein kinase-specific phosphorylation sites. HD Huang TY Lee SW Tseng JT Horng, Nucleic Acids Research 2005 33 226 229 10.1093/nar/gki471 (Pubitemid 44529913)
33. Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteins. F Diella S Cameron C Gemund R Linding A Via B Kuster T Sicheritz-Ponten N Blom TJ Gibson, BMC Bioinformatics 2004 22 79
34. Oct-2 DNA binding transcription factor: functional consequences of phosphorylation and glycosylation. I Ahmad DC Hoessli E Walker-Nasir SM Rafik AR Shakoori Nasir-ud-Din, Nucleic Acids Res 2006 34 175 184 10.1093/nar/gkj401 16431844 (Pubitemid 43167921)
35. CREB in long-term potentiation in hippocampus: role of post-translational modifications-studies In silico. A Kaleem DC Hoessli IU Haq E Walker-Nasir A Butt Z Iqbal Z Zamani AR Shakoori Nasir-ud-Din, J Cell Biochem 2011 112 138 146 10.1002/jcb.22909 21053365
36. In silico modulation of HMGN-1 binding to histones and gene expression by interplay of phosphorylation and O-GlcNAc modification. I Ahmad TS Khan DC Hoessli E Walker-Nasir A Kaleem AR Shakoori Nasir-ud-Din, Protein Pept Lett 2008 15 193 199 18289110 (Pubitemid 351346472)
37. Immediate-early gene regulation by interplay between different post-translational modifications on human histone H3. A Kaleem DC Hoessli I Ahmad E Walker-Nasir A Nasim AR Shakoori Nasir-ud-Din, J Cell Biochem 2008 103 835 851 10.1002/jcb.21454 17668447 (Pubitemid 351240619)
38. O-Glycosylation Prediction Electronic Tool (OGPET): a new algorithm for prediction of O-glycosylation sites. R Torres IC Almeida, FASEB J 2006 20 1362
39. UCSF Chimera - a visualization system for exploratory research and analysis. EF Pettersen TD Goddard CC Huang GS Couch DM Greenblatt EC Meng TE Ferrin, J Comput Chem 2004 25 1605 1612 10.1002/jcc.20084 15264254
40. I-TASSER server for protein 3D structure prediction. Y Zhang, BMC Bioinformatics 2008 9 40 10.1186/1471-2105-9-40 18215316
41. GRIS: Glycoprotein-hormone Receptor Information System. JV Durme F Horn S Costagliola G Vriend G Vassart, Molecular Endocrinology 2006 20 2247 2255 10.1210/me.2006-0020 16543405 (Pubitemid 44286717)
42. The PyMOL Molecular Graphics System. http://www.pymol.org/citing Version 1.3, Schrödinger, LLC
43. A generic method for assignment of reliability scores applied to solvent accessibility predictions. B Petersen TN Petersen P Andersen M Nielsen C Lundegaard, BMC Struct Biol 2009 9 51 10.1186/1472-6807-9-51 19646261
44. Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. JC Obenauer LC Cantley MB Yaffe, Nucleic Acids Res 2003 31 13 3635 3641 10.1093/nar/gkg584 12824383 (Pubitemid 37442212)
45. Bioinformatics: The machine learning Approach. P Baldi S Brunak, MIT Press Cambridge, MA 2 2002
46. Hepatitis C virus core protein transactivates insulin-like growth factor II gene transcription through acting concurrently on Egr1 and Sp1 sites. S Lee U Park YI Lee, Virology 2001 283 2 167 77 10.1006/viro.2001.0892 11336542 (Pubitemid 32881164)
47. The effects of phosphorylation on the structure and function of proteins. LN Johnson D Barford, Annu Rev Biophys Biomol Struct 1993 22 199 232 10.1146/annurev.bb.22.060193.001215 8347989 (Pubitemid 23180322)
48. Conformational changes in protein loops and helices induced by post-translational phosphorylation. ES Groban A Narayanan MP Jacobson, PLoS Comput Biol 2006 2 32 10.1371/journal.pcbi.0020032 16628247
49. Structural basis for the regulation of insulin-like growth factors by IGF binding proteins. I Siwanowicz GM Popowicz M Wisniewska R Huber KP Kuenkele K Lang RA Engh TA Holak, Structure 2005 13 155 167 10.1016/j.str.2004.11.009 15642270 (Pubitemid 40092483)
50. The insulin-like growth factor-binding protein (IGFBP) superfamily. V Hwa Y Oh RG Rosenfeld, Endocr Rev 1999 20 761 787 10.1210/er.20.6.761 10605625 (Pubitemid 30648894)
51. Physiological differences in insulin-like growth factor binding protein-1 (IGFBP-1) phosphorylation in IGFBP-1 transgenic mice. K Sakai AJ D'Ercole LJ Murphy DR Clemmons, Diabetes 2001 50 32 38 10.2337/diabetes.50.1.32 11147791 (Pubitemid 32047977)
52. O-glycosylation of nuclear and cytoplasmic proteins: regulation analogous to phosphorylation. RS Haltiwanger S Busby K Grove S Li D Mason L Medina D Moloney G Philipsberg R Scartozzi, J Biochem Biophys Res Commun 1997 231 237 242 10.1006/bbrc.1997.6110 (Pubitemid 27214290)
53. MDCK cells secrete neutral proteases cleaving insulin-like growth factor protein-2 to -6. L Shalamanova B Kubler JG Scharf T Braulke, Am j Physiol Endocrinol Metab 2001 281 1221 1226
54. Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts. L Xie G Tsaprailis QM Chen, Mol Cell Proteomics 2005 4 1273 1283 10.1074/mcp.M500032- MCP200 15958393 (Pubitemid 41448715)
55. IGFBP-6 plays a role as an oncosuppressor gene in NPC pathogenesis through regulating EGR-1 expression. YS Kuo YB Tang TY Lu HC Wu CT Lin, J Pathol 2010 222 299 309 10.1002/path.2735 20635349
56. Tyrosinase-catalyzed modification of Bombyx mori silk fibroin: grafting of chitosan under heterogeneous reaction conditions. G Freddi A Anghileri S Sampaio J Buchert P Monti P Taddei, J Biotechnol 2006 125 2 281 294 10.1016/j.jbiotec.2006.03.003 16621091 (Pubitemid 44192552)
57. O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. NE Zachara GW Hart, Biochim Biophys 2004 1673 13 28 (Pubitemid 38844791)