Provider perceptions of barriers to the emergency use of tPA for Acute Ischemic Stroke: A qualitative study

BMC Emergency Medicine

Volumn 11, Issue , 2011, Pages

  Meurer, William J ^a   Majersik, Jennifer J ^b   Frederiksen, Shirley M ^a   Kade, Allison M ^a   Sandretto, Annette M ^a   Scott, Phillip A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR; FIBRINOLYTIC AGENT;

ARTICLE; AWARENESS; BRAIN ISCHEMIA; EMERGENCY CARE; EMERGENCY PHYSICIAN; ENVIRONMENTAL FACTOR; HOSPITAL ADMINISTRATOR; HUMAN; MEDICAL STAFF; MOTIVATION; NURSE; OUTCOME ASSESSMENT; PATIENT PREFERENCE; PERCEPTION; PHARMACIST; PRACTICE GUIDELINE; QUALITATIVE RESEARCH; RADIOLOGIST; SELF CONCEPT; STRUCTURED INTERVIEW; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EMERGENCY; ENVIRONMENT; HEALTH PERSONNEL ATTITUDE; INFORMATION PROCESSING; PATIENT; RANDOMIZED CONTROLLED TRIAL; STROKE;

ATTITUDE OF HEALTH PERSONNEL; BRAIN ISCHEMIA; EMERGENCIES; ENVIRONMENT; FIBRINOLYTIC AGENTS; FOCUS GROUPS; GUIDELINE ADHERENCE; HUMANS; MOTIVATION; PATIENTS; PRACTICE GUIDELINES AS TOPIC; QUALITATIVE RESEARCH; SELF EFFICACY; STROKE; TISSUE PLASMINOGEN ACTIVATOR;

EID: 79955675055     PISSN: None     EISSN: 1471227X     Source Type: Journal    
DOI: 10.1186/1471-227X-11-5     Document Type: Article

References (22)

1. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O'Donnell C, Roger V, Sorlie P, Steinberger J, Thom T, Wilson M, Hong Y, . Committee ftAHAS, Stroke Statistics Subcommittee Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2008, 117(4):e25-146. Committee ftAHAS, Stroke Statistics Subcommittee.
2. Adams HP, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, Grubb RL, Higashida RT, Jauch EC, Kidwell C, Lyden PD, Morgenstern LB, Qureshi AI, Rosenwasser RH, Scott PA, Wijdicks EFM. Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke 2007, 38(5):1655-1711. 10.1161/STROKEAHA.107.181486, 17431204.
3. del Zoppo GJ, Saver JL, Jauch EC, Adams HP, . on behalf of the American Heart Association Stroke Council Expansion of the Time Window for Treatment of Acute Ischemic Stroke With Intravenous Tissue Plasminogen Activator. A Science Advisory From the American Heart Association/American Stroke Association. Stroke 2009, STROKEAHA.109.192535, on behalf of the American Heart Association Stroke Council.
4. Barber PA, Zhang J, Demchuk AM, Hill MD, Buchan AM. Why are stroke patients excluded from TPA therapy?: An analysis of patient eligibility. Neurology 2001, 56(8):1015-1020.
5. Schumacher HC, Bateman BT, Boden-Albala B, Berman MF, Mohr JP, Sacco RL, Pile-Spellman J. Use of Thrombolysis in Acute Ischemic Stroke: Analysis of the Nationwide Inpatient Sample 1999 to 2004. Annals of Emergency Medicine 2007, 50(2):99-107. 10.1016/j.annemergmed.2007.01.021, 17478010.
6. Kwan J, Hand P, Sandercock P. A systematic review of barriers to delivery of thrombolysis for acute stroke. Age Ageing 2004, 33(2):116-121. 10.1093/ageing/afh064, 14960425.
7. Morgenstern LB, Bartholomew LK, Grotta JC, Staub L, King M, Chan W. Sustained Benefit of a Community and Professional Intervention to Increase Acute Stroke Therapy. Arch Intern Med 2003, 163(18):2198-2202. 10.1001/archinte.163.18.2198, 14557217.
8. Greco PJ, Eisenberg JM. Changing physicians' practices. N Engl J Med 1993, 329(17):1271-1273. 10.1056/NEJM199310213291714, 8413397.
9. Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, Rubin HR. Why don't physicians follow clinical practice guidelines? A framework for improvement. Jama 1999, 282(15):1458-1465. 10.1001/jama.282.15.1458, 10535437.
10. Curry LA, Nembhard IM, Bradley EH. Qualitative and Mixed Methods Provide Unique Contributions to Outcomes Research. Circulation 2009, 119(10):1442-1452. 10.1161/CIRCULATIONAHA.107.742775, 19289649.
11. Scott PA. Enhancing Community Delivery of Tissue Plasminogen Activator in Stroke Through Community-Academic Collaborative Clinical Knowledge Translation. Emergency Medicine Clinics of North America 2009, 27(1):115-136. 10.1016/j.emc.2008.07.001, 2674264, 19218023.
12. Fonarow GC, Reeves MJ, Smith EE, Saver JL, Zhao X, Olson DW, Hernandez AF, Peterson ED, Schwamm LH, . Committee obotG-SS, Investigators Characteristics, Performance Measures, and In-Hospital Outcomes of the First One Million Stroke and Transient Ischemic Attack Admissions in Get With The Guidelines-Stroke. Circ Cardiovasc Qual Outcomes 2010, 3(3):291-302. 10.1161/CIRCOUTCOMES.109.921858, 20177051, Committee obotG-SS, Investigators.
13. Leira EC, Pary JK, Davis PH, Grimsman KJ, Adams HP. Slow Progressive Acceptance of Intravenous Thrombolysis for Patients With Stroke by Rural Primary Care Physicians. Arch Neurol 2007, 64(4):518-521. 10.1001/archneur.64.4.518, 17420312.
14. White-Bateman SR, Schumacher HC, Sacco RL, Appelbaum PS. Consent for Intravenous Thrombolysis in Acute Stroke: Review and Future Directions. Arch Neurol 2007, 64(6):785-792. 10.1001/archneur.64.6.785, 17562926.
15. Meurer WJ, Frederiksen SM, Majersik JJ, Zhang L, Sandretto A, Scott PA. Qualitative data collection and analysis methods: the INSTINCT trial. Acad Emerg Med 2007, 14(11):1064-1071.
16. Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care 2007, 19(6):349-357. 10.1093/intqhc/mzm042, 17872937.
17. Campbell M, Fitzpatrick R, Haines A, Kinmonth AL, Sandercock P, Spiegelhalter D, Tyrer P. Framework for design and evaluation of complex interventions to improve health. Bmj 2000, 321(7262):694-696. 10.1136/bmj.321.7262.694, 1118564, 10987780.
18. Hacke W, Kaste M, Bluhmki E, Brozman M, Davalos A, Guidetti D, Larrue V, Lees KR, Medeghri Z, Machnig T, Schneider D, von Kummer R, Wahlgren N, Toni D, . the ECASS Investigators Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke. N Engl J Med 2008, 359(13):1317-1329. 10.1056/NEJMoa0804656, 18815396, the ECASS Investigators.
19. Lyden P. Thrombolytic Therapy for Acute Stroke -- Not a Moment to Lose. N Engl J Med 2008, 359(13):1393-1395. 10.1056/NEJMe0806335, 18815401.
20. Katzan IL, Furlan AJ, Lloyd LE, Frank JI, Harper DL, Hinchey JA, Hammel JP, Qu A, Sila CA. Use of Tissue-Type Plasminogen Activator for Acute Ischemic Stroke: The Cleveland Area Experience. Jama 2000, 283(9):1151-1158. 10.1001/jama.283.9.1151, 10703777.
21. Hoffman J, Schriger D. A graphic reanalysis of the NINDS trial. Annals of Emergency Medicine 2009, 54(3):329-336. 10.1016/j.annemergmed.2009.03.019, 19464756.
22. Mitka M. Tensions Remain Over tPA for Stroke. JAMA 2003, 289(11):1363-1364. 10.1001/jama.289.11.1363, 12636438.