Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study

British Journal of Haematology

Volumn 145, Issue 2, 2009, Pages 221-226

  Yamagishi, Kazumasa ^b,c   Cushman, Mary ^d   Heckbert, Susan R ^e   Tsai, Michael Y ^f   Folsom, Aaron R ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d FLETCHER ALLEN HEALTH CARE   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Epidemiology; Follow up study; Risk factors; Thrombophilia; Venous thrombosis

Indexed keywords

ENDOTHELIAL PROTEIN C RECEPTOR;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PATHOGENESIS; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; SEX DIFFERENCE; VENOUS THROMBOEMBOLISM;

ANTIGENS, CD; CASE-CONTROL STUDIES; FEMALE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; RECEPTORS, CELL SURFACE; RISK; VENOUS THROMBOEMBOLISM;

EID: 63149130223     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07612.x     Document Type: Article

References (21)

1. Cushman, M., Cornell, E.S., Howard, P.R., Bovill, E.G. Tracy, R.P. (1995) Laboratory methods and quality assurance in the Cardiovascular Health Study. Clinical Chemistry, 41, 264 270.
2. Cushman, M., Tsai, A.W., White, R.H., Heckbert, S.R., Rosamond, W.D., Enright, P. Folsom, A.R. (2004) Deep vein thrombosis and pulmonary embolism in two cohorts: the Longitudinal Investigation of Thromboembolism Etiology. American Journal of Medicine, 117, 19 25.
3. Dählback, B. Villoutreix, B.O. (2005) The anticoagulant protein C pathway. FEBS Letters, 579, 3310 3316.
4. Esmon, C.T. (2006) The endothelial protein C receptor. Current Opinion in Hematology, 13, 382 385.
5. Folsom, A.R., Wu, K.K., Rosamond, W.D., Sharrett, A.R. Chambless, L.E. (1997) Prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. Circulation, 96, 1102 1108.
6. Folsom, A.R., Cushman, M., Tsai, M.Y., Aleksic, N., Heckbert, S.R., Boland, L.L., Tsai, A.W., Yanez, N.D. Rosamond, W.D. (2002a) A prospective study of venous thromboembolism in relation to factor V Leiden and related factors. Blood, 99, 2720 2725.
7. Folsom, A.R., Cushman, M., Tsai, M.Y., Heckbert, S.R. Aleksic, N. (2002b) Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism. American Journal of Hematology, 71, 285 290.
8. Folsom, A.R., Aleksic, N., Wang, L., Cushman, M., Wu, K.K. White, R.H. (2002c) Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study. Arteriosclerosis, Thrombosis, and Vascular Biology, 22, 1018 1022.
9. Fried, L.P., Borhani, N.O., Enright, P., Furberg, C.D., Gardin, J.M., Kronmal, R.A., Kuller, L.H., Manolio, T.A., Mittelmark, M.B. Newman, A. (1991) The Cardiovascular Health Study: design and rationale. Annals of Epidemiology, 1, 263 276.
10. Ghosh, S., Pendurthi, U.R., Steinoe, A., Esmon, C.T. Rao, L.V. (2007) Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium. Journal of Biological Chemisty, 282, 11849 11857.
11. López-Sagaseta, J., Montes, R., Puy, C., Díez, N., Fukudome, K. Hermida, J. (2007) Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity. Journal of Thrombosis and Haemostasis, 5, 1817 1824.
12. Medina, P., Navarro, S., Estelles, A., Vaya, A., Woodhams, B., Mira, Y., Villa, P., Migaud-Fressart, M., Ferrando, F. Aznar, J. (2004) Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk. Thrombosis and Haemostasis, 91, 905 911.
13. Ohira, T., Cushman, M., Tsai, M.Y., Zhang, Y., Heckbert, S.R., Zakai, N.A., Rosamond, W.D. Folsom, A.R. (2007) ABO blood group, other risk factors and incidence of venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE). Journal of Thrombosis and Haemostasis, 5, 1455 1461.
14. Poort, S.R., Rosendaal, F.R., Reitsma, P.H. Bertina, R.M. (1996) A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood, 88, 3698 3703.
15. de Ronde, H. Bertina, R.M. (1994) Laboratory diagnosis of APC-resistance: a critical evaluation of the test and the development of diagnostic criteria. Thrombosis and Haemostasis, 72, 880 886.
16. Saposnik, B., Reny, J.L., Gaussem, P., Emmerich, J., Aiach, M. Gandrille, S. (2004) A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis. Blood, 103, 1311 1318.
17. The ARIC Investigators 1989) The Atherosclerosis Risk in Communities (ARIC) study: design and objectives. American Journal of Epidemiology, 129, 687 702.
18. Tsai, A.W., Cushman, M., Rosamond, W.D., Heckbert, S.R., Polak, J.F. Folsom, A.R. (2002a) Cardiovascular risk factors and venous thromboembolism incidence: the Longitudinal Investigation of Thromboembolism Etiology. Archives of Internal Medicine, 162, 1182 1189.
19. Tsai, A.W., Cushman, M., Rosamond, W.D., Heckbert, S.R., Tracy, R.P., Aleksic, N. Folsom, A.R. (2002b) Coagulation factors, inflammation markers, and venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE). American Journal of Medicine, 113, 636 642.
20. Uitte de Willige, S., Van Marion, V., Rosendaal, F.R., Vos, H.L., de Visser, M.C. Bertina, R.M. (2004) Haplotypes of the EPCR gene, plasma sEPCR levels and the risk of deep venous thrombosis. Journal of Thrombosis and Haemostasis, 2, 1305 1310.
21. Van de Wouwer, M., Collen, D. Conway, E.M. (2004) Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, 1374 1383.