2,3-Dideoxy hex-2-enopyranosid-4-uloses as promising new anti-tubercular agents: Design, synthesis, biological evaluation and SAR studies

European Journal of Medicinal Chemistry

Volumn 46, Issue 6, 2011, Pages 2217-2223

  Saquib, Mohammad ^a   Husain, Irfan ^a   Sharma, Smriti ^a   Yadav, Garima ^a   Singh, Vipul K ^a   Sharma, Sandeep K ^a   Shah, Priyanka ^a   Siddiqi, Mohammad Imran ^a   Kumar, Brijesh ^a   Lal, Jawahar ^a   Jain, Girish K ^a   Srivastava, Brahm S ^a   Srivastava, Ranjana ^a   Shaw, Arun K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

, Unsaturated keto system; 2,3 Dideoxy hex 2 enopyranosid 4 uloses; Anti tubercular agents; Modified deoxy sugars; Non natural sugars; Small molecules

Indexed keywords

2,3 DIDEOXY HEX 2 ENOPYRANOSID 4 ULOSES; ETHAMBUTOL; ISONIAZID; RIFAMPICIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; HAPLORHINI; IN VITRO STUDY; KIDNEY CELL; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

ANIMALS; ANTITUBERCULAR AGENTS; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PYRONES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

EID: 79955634842     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.03.002     Document Type: Article

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