The actin cytoskeleton has an active role in the electrotransfer of plasmid DNA in mammalian cells

Molecular Therapy

Volumn 19, Issue 5, 2011, Pages 913-921

  Rosazza, Christelle ^a,b,c   Escoffre, Jean Michel ^a,b   Zumbusch, Andreas ^c   Rols, Marie Pierre ^a,b  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; DNA; LATRUNCULIN B; PLASMID DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL MEMBRANE; CHINESE HAMSTER; CONTROLLED STUDY; CYTOSKELETON; DNA BINDING; DNA TRANSFER; DRUG PROTEIN BINDING; ELECTRIC FIELD; ELECTROPORATION; GENE EXPRESSION; MAMMAL CELL; MICROFILAMENT; NONHUMAN; OVARY CELL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION;

CRICETULUS GRISEUS; MAMMALIA;

EID: 79955626209     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.303     Document Type: Article

References (50)

1. Young, LS, Searle, PF, Onion, D and Mautner, V (2006). Viral gene therapy strategies: from basic science to clinical application. J Pathol 208: 299-318. (Pubitemid 43126122)
2. Deshayes, S, Morris, MC, Divita, G and Heitz, F (2005). Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Cell Mol Life Sci 62: 1839-1849. (Pubitemid 41188523)
3. Karmali, PP and Chaudhuri, A (2007). Cationic liposomes as non-viral carriers of gene medicines: resolved issues, open questions, and future promises. Med Res Rev 27: 696-722. (Pubitemid 47282449)
4. Newman, CM and Bettinger, T (2007). Gene therapy progress and prospects: ultrasound for gene transfer. Gene Ther 14: 465-475. (Pubitemid 46390919)
5. Neumann, E, Schaefer-Ridder, M, Wang, Y and Hofschneider, PH (1982). Gene transfer into mouse lyoma cells by electroporation in high electric fields. EMBO J 1: 841-845.
6. Golzio, M, Rols, MP and Teissié, J (2004). In vitro and in vivo electric field-mediated permeabilization, gene transfer, and expression. Methods 33: 126-135. (Pubitemid 38578416)
7. Escoffre, JM, Portet, T, Wasungu, L, Teissié, J, Dean, D and Rols, MP (2009). What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues. Mol Biotechnol 41: 286-295.
8. Neumann, E and Rosenheck, K (1972). Permeability changes induced by electric impulses in vesicular membranes. J Membr Biol 10: 279-290.
9. Escoffre, JM, Dean, DS, Hubert, M, Rols, MP and Favard, C (2007). Membrane perturbation by an external electric field: a mechanism to permit molecular uptake. Eur Biophys J 36: 973-983. (Pubitemid 350045043)
10. Gehl, J (2003). Electroporation: theory and methods, perspectives for drug delivery, gene therapy and research. Acta Physiol Scand 177: 437-447. (Pubitemid 36411581)
11. Mir, LM, Gehl, J, Sersa, G, Collins, CG, Garbay, JR, Billard, V et al. (2006). Standard operating procedures of the electrochemotherapy: Instructions for the use of bleomycin or cisplatin administered either systemically or locally and electric pulses delivered by the Cliniporator (TM) by means of invasive or non-invasive electrodes. Ejc Suppl 4: 14-25. (Pubitemid 44755132)
12. André, F and Mir, LM (2004). DNA electrotransfer: its principles and an updated review of its therapeutic applications. Gene Ther 11 Suppl 1: S33-S42. (Pubitemid 39359445)
13. Daud, AI, DeConti, RC, Andrews, S, Urbas, P, Riker, AI, Sondak, VK et al. (2008). Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma. J Clin Oncol 26: 5896-5903.
14. Low, L, Mander, A, McCann, K, Dearnaley, D, Tjelle, T, Mathiesen, I et al. (2009). DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer. Hum Gene Ther 20: 1269-1278.
15. Hristova, NI, Tsoneva, I and Neumann, E (1997). Sphingosine-mediated electroporative DNA transfer through lipid bilayers. FEBS Lett 415: 81-86. (Pubitemid 27402054)
16. Klenchin, VA, Sukharev, SI, Serov, SM, Chernomordik, LV and Chizmadzhev YuA, (1991). Electrically induced DNA uptake by cells is a fast process involving DNA electrophoresis. Biophys J 60: 804-811.
17. Xie, TD and Tsong, TY (1993). Study of mechanisms of electric field-induced DNA transfection. V. Effects of DNA topology on surface binding, cell uptake, expression, and integration into host chromosomes of DNA in the mammalian cell. Biophys J 65: 1684-1689. (Pubitemid 23316988)
18. de Gennes, PG (1999). Passive entry of a DNA molecule into a small pore. Proc Natl Acad Sci USA 96: 7262-7264.
19. Golzio, M, Teissie, J and Rols, MP (2002). Direct visualization at the single-cell level of electrically mediated gene delivery. Proc Natl Acad Sci USA 99: 1292-1297. (Pubitemid 34136486)
20. Escoffre, JM, Portet, T, Favard, C, Teissié, J, Dean, DS and Rols, MP (2010). Electromediated formation of DNA complexes with cell membranes and its consequences for gene delivery. Biochim Biophys Acta (epub ahead of print).
21. Golzio, M, Mora, MP, Raynaud, C, Delteil, C, Teissié, J and Rols, MP (1998). Control by osmotic pressure of voltage-induced permeabilization and gene transfer in mammalian cells. Biophys J 74: 3015-3022. (Pubitemid 28268126)
22. Faurie, C, Rebersek, M, Golzio, M, Kanduser, M, Escoffre, JM, Pavlin, M et al. (2010). Electro-mediated gene transfer and expression are controlled by the life-time of DNA/ membrane complex formation. J Gene Med 12: 117-125.
23. Lukacs, GL, Haggie, P, Seksek, O, Lechardeur, D, Freedman, N and Verkman, AS (2000). Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem 275: 1625-1629. (Pubitemid 30060778)
24. Vaughan, EE and Dean, DA (2006). Intracellular trafficking of plasmids during transfection is mediated by microtubules. Mol Ther 13: 422-428. (Pubitemid 43056908)
25. Vaughan, EE, Geiger, RC, Miller, AM, Loh-Marley, PL, Suzuki, T, Miyata, N et al. (2008). Microtubule acetylation through HDAC6 inhibition results in increased transfection efficiency. Mol Ther 16: 1841-1847.
26. Verderame, M, Alcorta, D, Egnor, M, Smith, K and Pollack, R (1980). Cytoskeletal F-actin patterns quantitated with fluorescein isothiocyanate- phalloidin in normal and transformed cells. Proc Natl Acad Sci USA 77: 6624-6628. (Pubitemid 11219177)
27. Eynard, N, Rols, MP, Ganeva, V, Galutzov, B, Sabri, N, Teissie, J (1997). Electrotransformation pathways of prokaryotic and eukaryotic cells: recent developments. Bioelectrochem Bioenerg 44: 103-110. (Pubitemid 28018107)
28. Rols, MP, Dahhou, F, Mishra, KP and Teissié, J (1990). Control of electric field induced cell membrane permeabilization by membrane order. Biochemistry 29: 2960-2966. (Pubitemid 20119291)
29. Teissie, J and Rols, MP (1994). Manipulation of cell cytoskeleton affects the lifetime of cell membrane electropermeabilization. Ann N Y Acad Sci 720: 98-110. (Pubitemid 24200017)
30. Soldati, T and Schliwa, M (2006). Powering membrane traffic in endocytosis and recycling. Nat Rev Mol Cell Biol 7: 897-908. (Pubitemid 44871416)
31. Doherty, GJ and McMahon, HT (2009). Mechanisms of endocytosis. Annu Rev Biochem 78: 857-902.
32. Conner, SD and Schmid, SL (2003). Regulated portals of entry into the cell. Nature 422: 37-44. (Pubitemid 36323287)
33. Bellve, KD, Leonard, D, Standley, C, Lifshitz, LM, Tuft, RA, Hayakawa, A et al. (2006). Plasma membrane domains specialized for clathrin-mediated endocytosis in primary cells. J Biol Chem 281: 16139-16146. (Pubitemid 43848509)
34. Rols, MP, Femenia, P and Teissie, J (1995). Long-lived macropinocytosis takes place in electropermeabilized mammalian cells. Biochem Biophys Res Commun 208: 26-35.
35. Satkauskas, S, Bureau, MF, Mahfoudi, A and Mir, LM (2001). Slow accumulation of plasmid in muscle cells: supporting evidence for a mechanism of DNA uptake by receptor-mediated endocytosis. Mol Ther 4: 317-323. (Pubitemid 33040516)
36. Antov, Y, Barbul, A, Mantsur, H and Korenstein, R (2005). Electroendocytosis: exposure of cells to pulsed low electric fields enhances adsorption and uptake of macromolecules. Biophys J 88: 2206-2223. (Pubitemid 40976228)
37. Schafer, DA (2004). Regulating actin dynamics at membranes: a focus on dynamin. Traffic 5: 463-469. (Pubitemid 38923173)
38. Roux, A, Koster, G, Lenz, M, Sorre, B, Manneville, JB, Nassoy, P et al. (2010). Membrane curvature controls dynamin polymerization. Proc Natl Acad Sci USA 107: 4141-4146.
39. Römer, W, Berland, L, Chambon, V, Gaus, K, Windschiegl, B, Tenza, D et al. (2007). Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature 450: 670-675. (Pubitemid 350207679)
40. Ondrej, V, Lukásová, E, Falk, M and Kozubek, S (2007). The role of actin and microtubule networks in plasmid DNA intracellular trafficking. Acta Biochim Pol 54: 657-663. (Pubitemid 47584042)
41. Dauty, E and Verkman, AS (2005). Actin cytoskeleton as the principal determinant of size-dependent DNA mobility in cytoplasm: a new barrier for non-viral gene delivery. J Biol Chem 280: 7823-7828. (Pubitemid 40349677)
42. Ross, JL, Ali, MY and Warshaw, DM (2008). Cargo transport: molecular motors navigate a complex cytoskeleton. Curr Opin Cell Biol 20: 41-47.
43. Schafer, DA (2002). Coupling actin dynamics and membrane dynamics during endocytosis. Curr Opin Cell Biol 14: 76-81. (Pubitemid 34131660)
44. Bausinger, R, von Gersdorff, K, Braeckmans, K, Ogris, M, Wagner, E, Bräuchle, C et al. (2006). The transport of nanosized gene carriers unraveled by live-cell imaging. Angew Chem Int Ed Engl 45: 1568-1572. (Pubitemid 44105272)
45. Gouin, E, Welch, MD and Cossart, P (2005). Actin-based motility of intracellular pathogens. Curr Opin Microbiol 8: 35-45. (Pubitemid 40203224)
46. McDonald, D, Vodicka, MA, Lucero, G, Svitkina, TM, Borisy, GG, Emerman, M et al. (2002). Visualization of the intracellular behavior of HIV in living cells. J Cell Biol 159: 441-452. (Pubitemid 35332831)
47. Forest, T, Barnard, S and Baines, JD (2005). Active intranuclear movement of herpesvirus capsids. Nat Cell Biol 7: 429-431. (Pubitemid 40533134)
48. Lakadamyali, M, Rust, MJ, Babcock, HP and Zhuang, X (2003). Visualizing infection of individual influenza viruses. Proc Natl Acad Sci USA 100: 9280-9285. (Pubitemid 37033920)
49. Schelhaas, M, Ewers, H, Rajamäki, ML, Day, PM, Schiller, JT and Helenius, A (2008). Human papillomavirus type 16 entry: retrograde cell surface transport along actin-rich protrusions. PLoS Pathog 4: e1000148.
50. Sun, M, Northup, N, Marga, F, Huber, T, Byfield, FJ, Levitan, I et al. (2007). The effect of cellular cholesterol on membrane-cytoskeleton adhesion. J Cell Sci 120(Pt 13): 2223-2231. (Pubitemid 47074126)