Reaction of endogenous progenitor cells in a rat model of posttraumatic syringomyelia: Laboratory investigation

Journal of Neurosurgery: Spine

Volumn 14, Issue 5, 2011, Pages 573-582

  Tu, Jian ^a,c   Liao, Jinxin ^a   Stoodley, Marcus A ^a,c   Cunningham, Anne M ^b  

^a NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c MACQUARIE UNIVERSITY   (Australia)

Author keywords

Astrocyte; Endogenous progenitor cell; Glia; Oligodendroglial progenitor; Spinal cord injury; Stem cell; Syringomyelia

Indexed keywords

ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; KAOLIN; KI 67 ANTIGEN; NESTIN; PROTEIN ED1; PROTEOCHONDROITIN SULFATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARACHNOIDITIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EXCITOTOXICITY; GRAY MATTER; IMMUNOCYTOCHEMISTRY; LAMINECTOMY; MALE; MULTIPOTENT STEM CELL; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; RAT; SPINAL CORD CYST; SPINAL CORD INJURY; STEM CELL; SUBARACHNOID SPACE; SYRINGOMYELIA;

ANIMALS; ASTROCYTES; BIOLOGICAL MARKERS; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; ECTODYSPLASINS; GLIAL FIBRILLARY ACIDIC PROTEIN; KAOLIN; KI-67 ANTIGEN; OLIGODENDROGLIA; QUISQUALIC ACID; RATS; RATS, WISTAR; SPINAL CORD; SPINAL CORD INJURIES; STEM CELLS; SYRINGOMYELIA;

EID: 79955617644     PISSN: 15475654     EISSN: 15475646     Source Type: Journal    
DOI: 10.3171/2011.1.SPINE09491     Document Type: Article

References (50)

1. 3 by cells in normal and injured mouse spinal cord. J Neuropathol Exp Neurol 21:597-609, 1962
2. Altman J, Das GD: Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol 124:319-335, 1965
3. 3H-thymidine autoradiographic study. Exp Brain Res 46:315-323, 1982
4. Beattie MS, Bresnahan JC, Komon J, Tovar CA, Van Meter M, Anderson DK, et al: Endogenous repair after spinal cord contusion injuries in the rat. Exp Neurol 148:453-463, 1997 (Pubitemid 28068841)
5. Brodbelt AR, Stoodley MA, Watling A, Rogan C, Tu J, Brown CJ, et al: The role of excitotoxic injury in post-traumatic syringomyelia. J Neurotrauma 20:883-893, 2003 (Pubitemid 37159070)
6. Brodbelt AR, Stoodley MA, Watling AM, Tu J, Jones NR: Fluid flow in an animal model of post-traumatic syringomyelia. Eur Spine J 12:300-306, 2003 (Pubitemid 36783136)
7. Dervan AG, Roberts BL: Reaction of spinal cord central canal cells to cord transection and their contribution to cord regeneration. J Comp Neurol 458:293-306, 2003 (Pubitemid 36297917)
8. Eriksson PS, Perfilieva E, Björk-Eriksson T, Alborn AM, Nordborg C, Peterson DA, et al: Neurogenesis in the adult human hippocampus. Nat Med 4:1313-1317, 1998 (Pubitemid 28512114)
9. Faulkner JR, Herrmann JE, Woo MJ, Tansey KE, Doan NB, Sofroniew MV: Reactive astrocytes protect tissue and preserve function after spinal cord injury. J Neurosci 24:2143-2155, 2004 (Pubitemid 38314546)
10. Frisén J, Johansson CB, Török C, Risling M, Lendahl U: Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury. J Cell Biol 131:453-464, 1995
11. Fujiki M, Zhang Z, Guth L, Steward O: Genetic influences on cellular reactions to spinal cord injury: activation of macrophages/ microglia and astrocytes is delayed in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. J Comp Neurol 371:469-484, 1996 (Pubitemid 26286595)
12. Gage FH: Mammalian neural stem cells. Science 287:1433-1438, 2000
13. Gould E, McEwen BS, Tanapat P, Galea LA, Fuchs E: Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci 17:2492-2498, 1997 (Pubitemid 27137415)
14. Gould E, Reeves AJ, Graziano MS, Gross CG: Neurogenesis in the neocortex of adult primates. Science 286:548-552, 1999
15. Gould E, Vail N, Wagers M, Gross CG: Adult-generated hippocampal and neocortical neurons in macaques have a transient existence. Proc Natl Acad Sci U S A 98:10910-10917, 2001 (Pubitemid 32878718)
16. Hawryluk GWJ, Fehlings MG: The center of the spinal cord may be central to its repair. Cell Stem Cell 3:230-232, 2008
17. Hockfield S, McKay RD: Identification of major cell classes in the developing mammalian nervous system. J Neurosci 5:3310-3328, 1985 (Pubitemid 16182611)
18. Horky LL, Galimi F, Gage FH, Horner PJ: Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol 498:525-538, 2006 (Pubitemid 44232692)
19. Horner PJ, Power AE, Kempermann G, Kuhn HG, Palmer TD, Winkler J, et al: Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J Neurosci 20:2218-2228, 2000 (Pubitemid 30230075)
20. Kakulas BA: A review of the neuropathology of human spinal cord injury with emphasis on special features. J Spinal Cord Med 22:119-124, 1999
21. Kaplan MS, Bell DH: Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus. J Neurosci 4:1429-1441, 1984 (Pubitemid 14058662)
22. Kempermann G, Gast D, Kronenberg G, Yamaguchi M, Gage FH: Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development 130:391-399, 2003 (Pubitemid 36175935)
23. Kuhn HG, Dickinson-Anson H, Gage FH: Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 16:2027-2033, 1996 (Pubitemid 26144015)
24. Lang B, Liu HL, Liu R, Feng GD, Jiao XY, Ju G: Astrocytes in injured adult rat spinal cord may acquire the potential of neural stem cells. Neuroscience 128:775-783, 2004 (Pubitemid 39298430)
25. Lendahl U, Zimmerman LB, McKay RD: CNS stem cells express a new class of intermediate filament protein. Cell 60:585-595, 1990
26. Liu D, Thangnipon W, McAdoo DJ: Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord. Brain Res 547:344-348, 1991
27. Ma M, Basso DM, Walters P, Stokes BT, Jakeman LB: Behavioral and histological outcomes following graded spinal cord contusion injury in the C57Bl/6 mouse. Exp Neurol 169:239-254, 2001 (Pubitemid 32524420)
28. Marsala M, Sorkin LS, Yaksh TL: Transient spinal ischemia in rat: characterization of spinal cord blood flow, extracellular amino acid release, and concurrent histopathological damage. J Cereb Blood Flow Metab 14:604-614, 1994 (Pubitemid 24198403)
29. Meletis K, Barnabé-Heider F, Carlén M, Evergren E, Tomilin N, Shupliakov O, et al: Spinal cord injury reveals multilineage differentiation of ependymal cells. PLoS Biol 6:e182, 2008
30. Moriwaka F, Tashiro K, Tachibana S, Yada K: Epidemiology of syringomyelia in Japan - the nationwide survey. Rinsho Shinkeigaku 35:1395-1397, 1995 (Pubitemid 26198832)
31. Mothe AJ, Tator CH: Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat. Neuroscience 131:177-187, 2005 (Pubitemid 40170498)
32. Namiki J, Tator CH: Cell proliferation and nestin expression in the ependyma of the adult rat spinal cord after injury. J Neuropathol Exp Neurol 58:489-498, 1999 (Pubitemid 29220742)
33. Sasaki K, Murakami T, Kawasaki M, Takahashi M: The cell cycle associated change of the Ki-67 reactive nuclear antigen expression. J Cell Physiol 133:579-584, 1987 (Pubitemid 18014270)
34. Seki T, Fehlings MG: Mechanistic insights into posttraumatic syringomyelia based on a novel in vivo animal model. Laboratory investigation. J Neurosurg Spine 8:365-375, 2008 (Pubitemid 351489562)
35. Seri B, García-Verdugo JM, McEwen BS, Alvarez-Buylla A: Astrocytes give rise to new neurons in the adult mammalian hippocampus. J Neurosci 21:7153-7160, 2001 (Pubitemid 32846963)
36. Shibuya S, Miyamoto O, Auer RN, Itano T, Mori S, Norimatsu H: Embryonic intermediate filament, nestin, expression following traumatic spinal cord injury in adult rats. Neuroscience 114:905-916, 2002
37. Stoodley MA: Pathophysiology of syringomyelia. J Neurosurg 92:1069-1073, 2000 (Letter)
38. Stoodley MA, Brown SA, Brown CJ, Jones NR: Arterial pul sation-dependent perivascular cerebrospinal fluid flow into the central canal in the sheep spinal cord. J Neurosurg 86:686-693, 1997 (Pubitemid 27138639)
39. Stoodley MA, Gutschmidt B, Jones NR: Cerebrospinal fluid flow in an animal model of noncommunicating syringomyelia. Neurosurgery 44:1065-1076, 1999 (Pubitemid 29202867)
40. Stoodley MA, Jones NR, Brown CJ: Evidence for rapid fluid flow from the subarachnoid space into the spinal cord central canal in the rat. Brain Res 707:155-164, 1996 (Pubitemid 26056517)
41. Swanson RA, Ying W, Kauppinen TM: Astrocyte influences on ischemic neuronal death. Curr Mol Med 4:193-205, 2004 (Pubitemid 38425914)
42. Takahashi M, Arai Y, Kurosawa H, Sueyoshi N, Shirai S: Ependymal cell reactions in spinal cord segments after compression injury in adult rat. J Neuropathol Exp Neurol 62:185-194, 2003 (Pubitemid 36176953)
43. Tohyama T, Lee VM, Rorke LB, Marvin M, McKay RD, Trojanowski JQ: Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells. Lab Invest 66:303-313, 1992
44. Tramontin AD, García-Verdugo JM, Lim DA, Alvarez-Buylla A: Postnatal development of radial glia and the ventricular zone (VZ): a continuum of the neural stem cell compartment. Cereb Cortex 13:580-587, 2003
45. Urushitani M, Shimohama S, Kihara T, Sawada H, Akaike A, Ibi M, et al: Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: involvement of glutamate-induced nitric oxide in motor neuron toxicity and nonmotor neuron protection. Ann Neurol 44:796-807, 1998 (Pubitemid 28516051)
46. adult progenitor cells. J Cell Biol 116:167-176, 1992
47. Yamamoto S, Yamamoto N, Kitamura T, Nakamura K, Nakafuku M: Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp Neurol 172:115-127, 2001 (Pubitemid 33141159)
48. Yang H, Lu P, McKay HM, Bernot T, Keirstead H, Steward O, et al: Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury. J Neurosci 26:2157-2166, 2006 (Pubitemid 44699024)
49. Yang L, Jones NR, Stoodley MA, Blumbergs PC, Brown CJ: Excitotoxic model of post-traumatic syringomyelia in the rat. Spine 26:1842-1849, 2001
50. Zai LJ, Wrathall JR: Cell proliferation and replacement following contusive spinal cord injury. Glia 50:247-257, 2005 (Pubitemid 40769854)