Epstein-Barr virus latent gene sequences as geographical markers of viral origin: Unique ebna3 gene signatures identify Japanese viruses as distinct members of the Asian virus family

Journal of General Virology

Volumn 92, Issue 5, 2011, Pages 1032-1043

  Sawada, Akihisa ^a,b   Croom Carter, Deborah ^a   Kondo, Osamu ^b   Yasui, Masahiro ^b   Koyama Sato, Maho ^b   Inoue, Masami ^b   Kawa, Keisei ^b   Rickinson, Alan B ^a   Tierney, Rosemary J ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA A11 ANTIGEN;

ALLELE; ARTICLE; CONSENSUS; EBNA1 GENE; EBNA2 GENE; EBNA3 GENE; EBNA3A GENE; EBNA3B GENE; EBNA3C GENE; EPSTEIN BARR VIRUS; GENE; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; JAPANESE; LMP1 GENE; LYMPHOPROLIFERATIVE DISEASE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS GENE; VIRUS STRAIN;

DNA, VIRAL; EPSTEIN-BARR VIRUS INFECTIONS; EPSTEIN-BARR VIRUS NUCLEAR ANTIGENS; GENOTYPE; HERPESVIRUS 4, HUMAN; HUMANS; PHYLOGEOGRAPHY; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; VIRAL MATRIX PROTEINS;

HUMAN HERPESVIRUS 4;

EID: 79955617142     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.030023-0     Document Type: Article

References (42)

1. Bhatia, K., Raj, A., Guitierrez, M. I., Judde, J. G., Spangler, G., Venkatesh, H. & Magrath, I. T. (1996). Variation in the sequence of Epstein-Barr virus nuclear antigen 1 in normal peripheral blood lymphocytes and in Burkitt's lymphomas. Oncogene 13, 177-181.
2. Burrows, S. R., Gardner, J., Khanna, R., Steward, T., Moss, D. J., Rodda, S. & Suhrbier, A. (1994). Five new cytotoxic T cell epitopes identified within Epstein-Barr virus nuclear antigen 3. J Gen Virol 75, 2489-2493.
3. Burrows, J. M., Burrows, S. R., Poulsen, L. M., Sculley, T. B., Moss, D. J. & Khanna, R. (1996). Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: implications for virus evolution. J Virol 70, 2490-2496.
4. Burrows, J. M., Bromham, L., Woolfit, M., Piganeau, G., Tellam, J., Connolly, G., Webb, N., Poulsen, L., Cooper, L. & other authors (2004). Selection pressure-driven evolution of the Epstein-Barr virus-encoded oncogene LMP1 in virus isolates from Southeast Asia. J Virol 78, 7131-7137.
5. Chang, C. M., Yu, K. J., Mbulaiteye, S. M., Hildesheim, A. & Bhatia, K. (2009). The extent of genetic diversity of Epstein-Barr virus and its geographic and disease patterns: a need for reappraisal. Virus Res 143, 209-221.
6. Chen, Y. Y., Chang, K. L., Chen, W. G., Shibata, D., Hayashi, K. & Weiss, L. M. (1998). Epstein-Barr virus-associated nuclear antigen-1 carboxy-terminal gene sequences in Japanese and American patients with gastric carcinoma. Lab Invest 78, 877-882.
7. Chu, P. G., Chang, K. L., Chen, W. G., Chen, Y. Y., Shibata, D., Hayashi, K., Bacchi, C., Bacchi, M. & Weiss, L. M. (1999). Epstein-Barr virus (EBV) nuclear antigen (EBNA)-4 mutation in EBV-associated malignancies in three different populations. Am J Pathol 155, 941-947.
8. de Campos-Lima, P. O., Gavioli, R., Zhang, Q. J., Wallace, L. E., Dolcetti, R., Rowe, M., Rickinson, A. B. & Masucci, M. G. (1993). HLA-A11 epitope loss isolates of Epstein-Barr virus from a highly A11+ population. Science 260, 98-100.
9. de Campos-Lima, P. O., Levitsky, V., Brooks, J., Lee, S. P., Hu, L. F., Rickinson, A. B. & Masucci, M. G. (1994). T cell responses and virus evolution: loss of HLA A11-restricted CTL epitopes in Epstein-Barr virus isolates from highly A11-positive populations by selective mutation of anchor residues. J Exp Med 179, 1297-1305.
10. Edwards, R. H., Seillier-Moiseiwitsch, F. & Raab-Traub, N. (1999). Signature amino acid changes in latent membrane protein 1 distinguish Epstein-Barr virus strains. Virology 261, 79-95.
11. Ehlers, B., Spiess, K., Leendertz, F., Peeters, M., Boesch, C., Gatherer, D. & McGeoch, D. J. (2010). Lymphocryptovirus phylogeny and the origins of Epstein-Barr virus. J Gen Virol 91, 630-642.
12. Furutsuki, T., Hosoya, N., Kawana-Tachikawa, A., Tomizawa, M., Odawara, T., Goto, M., Kitamura, Y., Nakamura, T., Kelleher, A. D. & other authors (2004). Frequent transmission of cytotoxic-T-lympho-cyte escape mutants of human immunodeficiency virus type 1 in the highly HLA-A24-positive Japanese population. J Virol 78, 8437-8445.
13. Gavioli, R., Kurilla, M. G., de Campos-Lima, P. O., Wallace, L. E., Dolcetti, R., Murray, R. J., Rickinson, A. B. & Masucci, M. G. (1993). Multiple HLA A11-restricted cytotoxic T-lymphocyte epitopes of different immunogenicities in the Epstein-Barr virus-encoded nuclear antigen 4. J Virol 67, 1572-1578.
14. Görzer, I., Niesters, H. G., Cornelissen, J. J. & Puchhammer-Stöckl, E. (2006). Characterization of Epstein-Barr virus Type I variants based on linked polymorphism among EBNA3A, -3B, and -3C genes. Virus Res 118, 105-114.
15. Gratama, J. W., Oosterveer, M. A., Zwaan, F. E., Lepoutre, J., Klein, G. & Ernberg, I. (1988). Eradication of Epstein-Barr virus by allogeneic bone marrow transplantation: implications for sites of viral latency. Proc Natl Acad Sci USA 85, 8693-8696.
16. Habeshaw, G., Yao, Q. Y., Bell, A. I., Morton, D. & Rickinson, A. B. (1999). Epstein-Barr virus nuclear antigen 1 sequences in endemic and sporadic Burkitt's lymphoma reflect virus strains prevalent in different geographic areas. J Virol 73, 965-975.
17. Hislop, A. D., Taylor, G. S., Sauce, D. & Rickinson, A. B. (2007). Cellular responses to viral infection in humans: lessons from Epstein-Barr virus. Annu Rev Immunol 25, 587-617.
18. Junying, J., Herrmann, K., Davies, G., Lissauer, D., Bell, A., Timms, J., Reynolds, G. M., Hubscher, S. G., Young, L. S. & other authors (2003). Absence of Epstein-Barr virus DNA in the tumor cells of European hepatocellular carcinoma. Virology 306, 236-243.
19. Kanno, H., Nakatsuka, S., Iuchi, K. & Aozasa, K. (2000). Sequences of cytotoxic T-lymphocyte epitopes in the Epstein-Barr virus (EBV) nuclear antigen-3B gene in a Japanese population with or without EBV-positive lymphoid malignancies. Int J Cancer 88, 626-632.
20. Kashiwagi, Y., Kawashima, H., Sato, S., Ioi, H., Amaha, M., Takekuma, K., Hoshika, A., Oshiro, H., Matsubayashi, J. & Mukai, K. (2007). Virological and immunological characteristics of fatal virus-associated haemophagocytic syndrome (VAHS). Microbiol Immunol 51, 53-62.
21. Kawa, K. (2003). Diagnosis and treatment of Epstein-Barr virus-associated natural killer cell lymphoproliferative disease. Int J Hematol 78, 24-31.
22. Kawa, K., Sawada, A., Koyama, M. & Inoue, M. (2007). Epstein-Barr virus infection after unrelated cord blood transplantation: reactivation or reinfection? Int J Hematol 85, 267-269.
23. Khanna, R., Slade, R. W., Poulsen, L. M., Moss, D. J., Burrows, S. R., Nicholls, J. & Burrows, J. M. (1997). Evolutionary dynamics of genetic variation in Epstein-Barr virus isolates of diverse geographical origins: evidence for immune pressure-independent genetic drift. J Virol 71, 8340-8346.
24. Kikuta, H., Taguchi, Y., Tomizawa, K., Kojima, K., Kawamura, N., Ishizaka, A., Sakiyama, Y., Matsumoto, S., Imai, S. & other authors (1988). Epstein-Barr virus genome-positive T lymphocytes in a boy with chronic active EBV infection associated with Kawasaki-like disease. Nature 333, 455-457.
25. Kimura, H. (2006). Pathogenesis of chronic active Epstein-Barr virus infection: is this an infectious disease, lymphoproliferative disorder, or immunodeficiency? Rev Med Virol 16, 251-261.
26. McGeoch, D. J. & Gatherer, D. (2007). Lineage structures in the genome sequences of three Epstein-Barr virus strains. Virology 359, 1-5.
27. Midgley, R. S., Blake, N. W., Yao, Q. Y., Croom-Carter, D. S. G., Cheung, S. T., Leung, S. F., Chan, A. T. C., Johnson, P. J., Huang, D. & other authors (2000). Novel intertypic recombinants of Epstein-Barr virus in the Chinese population. J Virol 74, 1544-1548.
28. Midgley, R. S., Bell, A. I., McGeoch, D. J. & Rickinson, A. B. (2003a). Latent gene sequencing reveals familial relationships among Chinese Epstein-Barr virus strains and evidence for positive selection of A11 epitope changes. J Virol 77, 11517-11530.
29. Midgley, R. S., Bell, A. I., Yao, Q. Y., Croom-Carter, D., Hislop, A. D., Whitney, B. M., Chan, A. T., Johnson, P. J. & Rickinson, A. B. (2003b). HLA-A11-restricted epitope polymorphism among Epstein-Barr virus strains in the highly HLA-A11-positive Chinese population: incidence and immunogenicity of variant epitope sequences. J Virol 77, 11507-11516.
30. Miller, W. E., Edwards, R. H., Walling, D. M. & Raab-Traub, N. (1994). Sequence variation in the Epstein-Barr virus latent membrane protein 1. J Gen Virol 75, 2729-2740.
31. Ohshima, K., Kimura, H., Yoshino, T., Kim, C. W., Ko, Y. H., Lee, S. S., Peh, S. C., Chan, J. K. & CAEBV Study Group (2008). Proposed categorization of pathological states of EBV-associated T/natural killer-cell lymphoproliferative disorder (LPD) in children and young adults: overlap with chronic active EBV infection and infantile fulminant EBV T-LPD. Pathol Int 58, 209-217.
32. Oshima, M., Azuma, H. & Okuno, A. (1999). High prevalence of Epstein-Barr virus type A strain with the 30 b.p. deletion of the latent membrane protein-1 gene in a Japanese population. Pediatr Int 41, 490-495.
33. Rickinson, A. B. & Kieff, E. (2007). Epstein-Barr virus. In Fields Virology, 5th edn, pp. 2655-2700. Edited by D. M. Knipe & P. M. Howley. Philadelphia: Lippincott, Williams & Wilkins.
34. Sample, J., Young, L., Martin, B., Chatman, T., Kieff, E., Rickinson, A. & Kieff, E. (1990). Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes. J Virol 64, 4084-4092.
35. Sandvej, K., Zhou, X. G. & Hamilton-Dutoit, S. (2000). EBNA-1 sequence variation in Danish and Chinese EBV-associated tumours: evidence for geographical polymorphism but not for tumour-specific subtype restriction. J Pathol 191, 127-131.
36. Schuster, V., Ott, G., Seidenspinner, S. & Kreth, H. W. (1996). Common Epstein-Barr virus (EBV) type-1 variant strains in both malignant and benign EBV-associated disorders. Blood 87, 1579-1585.
37. Sitki-Green, D., Edwards, R. H., Webster-Cyriaque, J. & Raab-Traub, N. (2002). Identification of Epstein-Barr virus strain variants in hairy leukoplakia and peripheral blood by use of a heteroduplex tracking assay. J Virol 76, 9645-9656.
38. Sitki-Green, D., Covington, M. & Raab-Traub, N. (2003). Compartmentalization and transmission of multiple Epstein-Barr virus strains in asymptomatic carriers. J Virol 77, 1840-1847.
39. Tierney, R. J., Edwards, R. H., Sitki-Green, D., Croom-Carter, D., Roy, S., Yao, Q. Y., Raab-Traub, N. & Rickinson, A. B. (2006). Multiple Epstein-Barr virus strains in patients with infectious mononucleosis: comparison of ex vivo samples with in vitro isolates by use of heteroduplex tracking assays. J Infect Dis 193, 287-297.
40. Wang, F., Rivailler, P., Rao, P. & Cho, Y. (2001). Simian homologues of Epstein-Barr virus. Philos Trans R Soc Lond B Biol Sci 356,489-497.
41. Xu, Z. G., Iwatsuki, K., Ohtsuka, M., Oyama, N., Matsui, T. & Kaneko, F. (2000). Polymorphism analysis of Epstein-Barr virus isolates from patients with cutaneous natural killer/T-cell lymphoproliferative disorders: a possible relation to the endemic occurrence of these diseases in Japan. J Med Virol 62, 239-246.
42. Yao, Q. Y., Tierney, R. J., Croom-Carter, D., Cooper, G. M., Ellis, C. J., Rowe, M. & Rickinson, A. B. (1996). Isolation of intertypic recombinants of Epstein-Barr virus from T-cell-immunocompro-mised individuals. J Virol 70, 4895-4903.