Stromal vascular fraction from adipose tissue forms profound vascular network through the dynamic reassembly of blood endothelial cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 5, 2011, Pages 1141-1150

  Koh, Young Jun ^a   Koh, Bong Ihn ^a   Kim, Honsoul ^a   Joo, Hyung Joon ^a   Jin, Ho Kyoung ^a   Jeon, Jongwook ^a   Choi, Chulhee ^a   Lee, Dong Hun ^b   Chung, Jin Ho ^b   Cho, Chung Hyun ^c   Park, Won Seok ^d   Ryu, Ji Kan ^e   Suh, Jun Kyu ^e   Koh, Gou Young ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

^d AmorePacific Corporation   (South Korea)

^e Inha University School of Medicine   (South Korea)

Author keywords

angiogenesis; ischemia; vascular biology

Indexed keywords

FAT; VASCULOTROPIN;

ADIPOSE TISSUE; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; BLOOD VESSEL TRANSPLANTATION; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; HINDLIMB; LIMB ISCHEMIA; LIPID ABSORPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STROMA; STROMAL VASCULAR FRACTION; VASCULAR ENDOTHELIUM;

ABSORPTION; ADIPOSE TISSUE; ANGIOGENIC PROTEINS; ANIMALS; CELL DIFFERENTIATION; COLLAGEN; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; ENDOTHELIAL CELLS; GREEN FLUORESCENT PROTEINS; HINDLIMB; ISCHEMIA; LAMININ; LUMINESCENT PROTEINS; MACROPHAGES; MESENCHYMAL STEM CELL TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, NUDE; MICE, TRANSGENIC; MUSCLE, SKELETAL; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEOGLYCANS; REGIONAL BLOOD FLOW; SPHEROIDS, CELLULAR; STROMAL CELLS; TIME FACTORS;

EID: 79955603409     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.218206     Document Type: Article

References (42)

1. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P, Hedrick MH. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell. 2002;13:4279-4295. (Pubitemid 35471185)
2. Gimble JM, Katz AJ, Bunnell BA. Adipose-derived stem cells for regenerative medicine. Circ Res. 2007;100:1249-1260. (Pubitemid 46742916)
3. Tang W, Zeve D, Suh JM, Bosnakovski D, Kyba M, Hammer RE, Tallquist MD, Graff JM. White fat progenitor cells reside in the adipose vasculature. Science. 2008;322:583-586.
4. Han J, Koh YJ, Moon HR, Ryoo HG, Cho CH, Kim I, Koh GY. Adipose tissue is an extramedullary reservoir for functional hematopoietic stem and progenitor cells. Blood. 2010;115:957-964.
5. Bunnell BA, Flaat M, Gagliardi C, Patel B, Ripoll C. Adipose-derived stem cells: isolation, expansion and differentiation. Methods. 2008;45: 115-120. (Pubitemid 351885360)
6. Fraser JK, Wulur I, Alfonso Z, Hedrick MH. Fat tissue: an underappreciated source of stem cells for biotechnology. Trends Biotechnol. 2006; 24:150-154.
7. Murohara T, Shintani S, Kondo K. Autologous adipose-derived regenerative cells for therapeutic angiogenesis. Curr Pharm Des. 2009;15: 2784-2790.
8. Zuk PA. The adipose-derived stem cell: looking back and looking ahead. Mol Biol Cell. 2010;21:1783-1787.
9. Chen X, Aledia AS, Popson SA, Him L, Hughes CC, George SC. Rapid anastomosis of endothelial progenitor cell-derived vessels with host vasculature is promoted by a high density of cotransplanted fibroblasts. Tissue Eng Part A. 2010;16:585-594.
10. Kniazeva E, Putnam AJ. Endothelial cell traction and ECM density influence both capillary morphogenesis and maintenance in 3-D. Am J Physiol Cell Physiol. 2009;297:C179-C187.
11. Schechner JS, Nath AK, Zheng L, Kluger MS, Hughes CC, Sierra- Honigmann MR, Lorber MI, Tellides G, Kashgarian M, Bothwell AL, Pober JS. In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse. Proc Natl Acad Sci USA. 2000;97:9191-9196. (Pubitemid 30626696)
12. Shepherd BR, Enis DR, Wang F, Suarez Y, Pober JS, Schechner JS. Vascularization and engraftment of a human skin substitute using circulating progenitor cell-derived endothelial cells. FASEB J. 2006;20: 1739-1741.
13. Losordo DW, Dimmeler S. Therapeutic angiogenesis and vasculogenesis for ischemic disease: part I: angiogenic cytokines. Circulation. 2004;109: 2487-2491. (Pubitemid 38720544)
14. Shepherd BR, Chen HY, Smith CM, Gruionu G, Williams SK, Hoying JB. Rapid perfusion and network remodeling in a microvascular construct after implantation. Arterioscler Thromb Vasc Biol. 2004;24:898-904. (Pubitemid 38620869)
15. Miranville A, Heeschen C, Sengenes C, Curat CA, Busse R, Bouloumie A. Improvement of postnatal neovascularization by human adipose tissuederived stem cells. Circulation. 2004;110:349-355. (Pubitemid 38955505)
16. Planat-Benard V, Silvestre JS, Cousin B, Andre M, Nibbelink M, Tamarat R, Clergue M, Manneville C, Saillan-Barreau C, Duriez M, Tedgui A, Levy B, Penicaud L, Casteilla L. Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives. Circulation. 2004;109:656-663. (Pubitemid 38198874)
17. Nakagami H, Maeda K, Morishita R, Iguchi S, Nishikawa T, Takami Y, Kikuchi Y, Saito Y, Tamai K, Ogihara T, Kaneda Y. Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vasc Biol. 2005;25:2542-2547. (Pubitemid 43732276)
18. Kondo K, Shintani S, Shibata R, Murakami H, Murakami R, Imaizumi M, Kitagawa Y, Murohara T. Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. Arterioscler Thromb Vasc Biol. 2009;29:61-66.
19. Young C, Jarrell BE, Hoying JB, Williams SK. A porcine model for adipose tissue-derived endothelial cell transplantation. Cell Transplant. 1992;1:293-298.
20. Williams SK, Wang TF, Castrillo R, Jarrell BE. Liposuction-derived human fat used for vascular graft sodding contains endothelial cells and not mesothelial cells as the major cell type. J Vasc Surg. 1994;19: 916-923. (Pubitemid 24149938)
21. Traktuev DO, Merfeld-Clauss S, Li J, Kolonin M, Arap W, Pasqualini R, Johnstone BH, March KL. A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res. 2008;102:77-85.
22. Traktuev DO, Prater DN, Merfeld-Clauss S, Sanjeevaiah AR, Saadatzadeh MR, Murphy M, Johnstone BH, Ingram DA, March KL. Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells. Circ Res. 2009;104:1410-1420.
23. Kaufman MR, Miller TA, Huang C, Roostaeian J, Wasson KL, Ashley RK, Bradley JP. Autologous fat transfer for facial recontouring: is there science behind the art? Plast Reconstr Surg. 2007;119:2287-2296. (Pubitemid 46847129)
24. Bircoll M. Cosmetic breast augmentation utilizing autologous fat and liposuction techniques. Plast Reconstr Surg. 1987;79:267-271. (Pubitemid 17017003)
25. Lu F, Li J, Gao J, Ogawa R, Ou C, Yang B, Fu B. Improvement of the survival of human autologous fat transplantation by using vegftransfected adipose-derived stem cells. Plast Reconstr Surg. 2009;124: 1437-1446.
26. Hong SJ, Lee JH, Hong SM, Park CH. Enhancing the viability of fat grafts using new transfer medium containing insulin and-fibroblast growth factor in autologous fat transplantation. J Plast Reconstr Aesthet Surg. 2010;63:1202-1208.
27. Mackay DR, Manders EK, Saggers GC, Schenden MJ, Zaino R. The fate of dermal and dermal-fat grafts. Ann Plast Surg. 1993;31:42-46. (Pubitemid 23204447)
28. Cho CH, Kammerer RA, Lee HJ, Steinmetz MO, Ryu YS, Lee SH, Yasunaga K, Kim KT, Kim I, Choi HH, Kim W, Kim SH, Park SK, Lee GM, Koh GY. COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity. Proc Natl Acad Sci USA. 2004;101: 5547-5552. (Pubitemid 38481194)
29. Motoike T, Loughna S, Perens E, Roman BL, Liao W, Chau TC, Richardson CD, Kawate T, Kuno J, Weinstein BM, Stainier DY, Sato TN. Universal GFP reporter for the study of vascular development. Genesis. 2000;28:75-81.
30. Cho CH, Koh YJ, Han J, Sung HK, Jong Lee H, Morisada T, Schwendener RA, Brekken RA, Kang G, Oike Y, Choi TS, Suda T, Yoo OJ, Koh GY. Angiogenic role of LYVE-1-positive macrophages in adipose tissue. Circ Res. 2007;100:e47-e57. (Pubitemid 46673270)
31. Zeisberger SM, Odermatt B, Marty C, Zehnder-Fjallman AH, Ballmer-Hofer K, Schwendener RA. Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach. Br J Cancer. 2006;95:272-281. (Pubitemid 44187587)
32. Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R. CD8 effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med. 2009;15:914-920.
33. Kang Y, Choi M, Lee J, Koh GY, Kwon K, Choi C. Quantitative analysis of peripheral tissue perfusion using spatiotemporal molecular dynamics. PLoS One. 2009;4:e4275.
34. Dastoor SF, Misch CE, Wang HL. Dermal fillers for facial soft tissue augmentation. J Oral Implantol. 2007;33:191-204.
35. Kreisel D, Krupnick AS, Gelman AE, Engels FH, Popma SH, Krasinskas AM, Balsara KR, Szeto WY, Turka LA, Rosengard BR. Nonhematopoietic allograft cells directly activate CD8 T cells and trigger acute rejection: an alternative mechanism of allorecognition. Nat Med. 2002;8:233-239. (Pubitemid 34250100)
36. Risau W. Mechanisms of angiogenesis. Nature. 1997;386:671-674. (Pubitemid 27193480)
37. Carmeliet P. Angiogenesis in life, disease and medicine. Nature. 2005; 438:932-936. (Pubitemid 43093958)
38. Melero-Martin JM, De Obaldia ME, Allen P, Dudley AC, Klagsbrun M, Bischoff J. Host myeloid cells are necessary for creating bioengineered human vascular networks in vivo. Tissue Eng Part A. 2010;16: 2457-2466.
39. Katz AJ, Tholpady A, Tholpady SS, Shang H, Ogle RC. Cell surface and transcriptional characterization of human adipose-derived adherent stromal (HADAS) cells. Stem Cells. 2005;23:412-423. (Pubitemid 40404460)
40. Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, Park TS, Andriolo G, Sun B, Zheng B, Zhang L, Norotte C, Teng PN, Traas J, Schugar R, Deasy BM, Badylak S, Buhring HJ, Giacobino JP, Lazzari L, Huard J, Peault B. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell. 2008;3:301-313.
41. Campagnolo P, Cesselli D, Zen AAH, Beltrami AP, Krankel N, Katare R, Angelini G, Emanueli C, Madeddu P. Human adult vena saphena contains perivascular progenitor cells endowed with clonogenic and proangiogenic potential. Circulation. 2010;121:1735-1745.
42. Choi JH, Gimble JM, Lee K, Marra KG, Rubin JP, Yoo JJ, Vunjak- Novakovic G, Kaplan DL. Adipose tissue engineering for soft tissue regeneration. Tissue Eng Part B Rev. 2010;16:413-426.