Zebrafish her8a is activated by su(h)-dependent notch signaling and is essential for the inhibition of neurogenesis

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Chung, Pei Chen ^a   Lin, Wen Shiuan ^a   Scotting, Paul J ^b   Hsieh, Fu Yu ^a   Wu, Hui Lan ^a   Cheng, Yi Chuan ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHOLINE DERIVATIVE; NOTCH RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HES 6; UNCLASSIFIED DRUG; ANTISENSE OLIGONUCLEOTIDE; HER8A PROTEIN, ZEBRAFISH; HOMEODOMAIN PROTEIN; NERVE PROTEIN; NOTCH1 RECEPTOR; NOTCH1A PROTEIN, ZEBRAFISH; SUPPRESSOR OF HAIRLESS PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE; GENE EXPRESSION; GENETIC REGULATION; GENETIC VARIABILITY; GLIA CELL; HER8A GENE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; WILD TYPE; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; CHEMISTRY; CONGENITAL MALFORMATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; GLIA; METABOLISM; MOLECULAR GENETICS; NERVOUS SYSTEM; NEURAL STEM CELL; PATHOLOGY; PHENOTYPE; PHYLOGENY; PRENATAL DEVELOPMENT; UPREGULATION;

DANIO RERIO; MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HOMEODOMAIN PROTEINS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; NEURAL STEM CELLS; NEUROGENESIS; NEUROGLIA; OLIGONUCLEOTIDES, ANTISENSE; PHENOTYPE; PHYLOGENY; RECEPTOR, NOTCH1; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UP-REGULATION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 79955600634     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019394     Document Type: Article

References (41)

1. Louvi A, Artavanis-Tsakonas S, (2006) Notch signalling in vertebrate neural development. Nat Rev Neurosci 7: 93-102.
2. Roy M, Pear WS, Aster JC, (2007) The multifaceted role of Notch in cancer. Curr Opin Genet Dev 17: 52-59.
3. Kageyama R, Ohtsuka T, Kobayashi T, (2007) The Hes gene family: repressors and oscillators that orchestrate embryogenesis. Development 134: 1243-1251.
4. Hans S, Scheer N, Riedl I, v Weizsacker E, Blader P, et al. (2004) her3, a zebrafish member of the hairy-E(spl) family, is repressed by Notch signalling. Development 131: 2957-2969.
5. Bae S, Bessho Y, Hojo M, Kageyama R, (2000) The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation. Development 127: 2933-2943.
6. Koyano-Nakagawa N, Kim J, Anderson D, Kintner C, (2000) Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation. Development 127: 4203-4216.
7. Sieger D, Tautz D, Gajewski M, (2004) her11 is involved in the somitogenesis clock in zebrafish. Dev Genes Evol 214: 393-406.
8. Takke C, Dornseifer P, v Weizsacker E, Campos-Ortega JA, (1999) her4, a zebrafish homologue of the Drosophila neurogenic gene E(spl), is a target of NOTCH signalling. Development 126: 1811-1821.
9. Geling A, Plessy C, Rastegar S, Strahle U, Bally-Cuif L, (2004) Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary. Development 131: 1993-2006.
10. Pasini A, Henrique D, Wilkinson DG, (2001) The zebrafish Hairy/Enhancer-of-split-related gene her6 is segmentally expressed during the early development of hindbrain and somites. Mech Dev 100: 317-321.
11. Leve C, Gajewski M, Rohr KB, Tautz D, (2001) Homologues of c-hairy1 (her9) and lunatic fringe in zebrafish are expressed in the developing central nervous system, but not in the presomitic mesoderm. Dev Genes Evol 211: 493-500.
12. Zhong TP, Rosenberg M, Mohideen MA, Weinstein B, Fishman MC, (2000) gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science 287: 1820-1824.
13. Bae YK, Shimizu T, Hibi M, (2005) Patterning of proneuronal and inter-proneuronal domains by hairy- and enhancer of split-related genes in zebrafish neuroectoderm. Development 132: 1375-1385.
14. Takke C, Campos-Ortega JA, (1999) her1, a zebrafish pair-rule like gene, acts downstream of notch signalling to control somite development. Development 126: 3005-3014.
15. Ninkovic J, Tallafuss A, Leucht C, Topczewski J, Tannhauser B, et al. (2005) Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair. Development 132: 75-88.
16. Gajewski M, Voolstra C, (2002) Comparative analysis of somitogenesis related genes of the hairy/Enhancer of split class in Fugu and zebrafish. BMC Genomics 3: 21.
17. Davis RL, Turner DL, (2001) Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning. Oncogene 20: 8342-8357.
18. Fior R, Henrique D, (2005) A novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis. Dev Biol 281: 318-333.
19. Belanger-Jasmin S, Llamosas E, Tang Y, Joachim K, Osiceanu AM, et al. (2007) Inhibition of cortical astrocyte differentiation by Hes6 requires amino- and carboxy-terminal motifs important for dimerization and phosphorylation. J Neurochem 103: 2022-2034.
20. Jhas S, Ciura S, Belanger-Jasmin S, Dong Z, Llamosas E, et al. (2006) Hes6 inhibits astrocyte differentiation and promotes neurogenesis through different mechanisms. J Neurosci 26: 11061-11071.
21. Latimer AJ, Dong X, Markov Y, Appel B, (2002) Delta-Notch signaling induces hypochord development in zebrafish. Development 129: 2555-2563.
22. Latimer AJ, Shin J, Appel B, (2005) her9 promotes floor plate development in zebrafish. Dev Dyn 232: 1098-1104.
23. Fadool JM, Dowling JE, (2008) Zebrafish: a model system for the study of eye genetics. Prog Retin Eye Res 27: 89-110.
24. Hu M, Easter SS, (1999) Retinal neurogenesis: the formation of the initial central patch of postmitotic cells. Dev Biol 207: 309-321.
25. Fischer A, Gessler M, (2007) Delta-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res 35: 4583-4596.
26. Jiang YJ, Brand M, Heisenberg CP, Beuchle D, Furutani-Seiki M, et al. (1996) Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development 123: 205-216.
27. Itoh M, Kim CH, Palardy G, Oda T, Jiang YJ, et al. (2003) Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev Cell 4: 67-82.
28. Ramain P, Khechumian K, Seugnet L, Arbogast N, Ackermann C, et al. (2001) Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. Curr Biol 11: 1729-1738.
29. Wettstein DA, Turner DL, Kintner C, (1997) The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesis. Development 124: 693-702.
30. Cheng YC, Amoyel M, Qiu X, Jiang YJ, Xu Q, et al. (2004) Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain. Dev Cell 6: 539-550.
31. Lefebvre V, Dumitriu B, Penzo-Mendez A, Han Y, Pallavi B, (2007) Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors. Int J Biochem Cell Biol 39: 2195-2214.
32. Okuda Y, Yoda H, Uchikawa M, Furutani-Seiki M, Takeda H, et al. (2006) Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution. Dev Dyn 235: 811-825.
33. Shih YH, Kuo CL, Hirst CS, Dee CT, Liu YR, et al. (2010) SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling. Development 137: 2671-2681.
34. Storck T, Schulte S, Hofmann K, Stoffel W, (1992) Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci U S A 89: 10955-10959.
35. Shibata T, Yamada K, Watanabe M, Ikenaka K, Wada K, et al. (1997) Glutamate transporter GLAST is expressed in the radial glia-astrocyte lineage of developing mouse spinal cord. J Neurosci 17: 9212-9219.
36. Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, et al. (2007) p53 activation by knockdown technologies. PLoS Genet 3: e78.
37. Sela-Donenfeld D, Kayam G, Wilkinson DG, (2009) Boundary cells regulate a switch in the expression of FGF3 in hindbrain rhombomeres. BMC Dev Biol 9: 16.
38. Kawamura A, Koshida S, Hijikata H, Sakaguchi T, Kondoh H, et al. (2005) Zebrafish hairy/enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites. Genes Dev 19: 1156-1161.
39. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG, (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25: 4876-4882.
40. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF, (1995) Stages of embryonic development of the zebrafish. Dev Dyn 203: 253-310.
41. Xu Q, Alldus G, Holder N, Wilkinson DG, (1995) Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. Development 121: 4005-4016.