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Volumn 24, Issue 5, 2011, Pages 720-728

Molecular mechanisms of epidermal growth factor receptor overexpression in patients with cervical cancer

Author keywords

aneuploidy; cervical cancer; E5; E6; epidermal growth factor receptor; HPV

Indexed keywords

APOLIPOPROTEIN E5; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; PROTEIN E6;

EID: 79955592688     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2010.239     Document Type: Article
Times cited : (47)

References (41)
  • 2
    • 1542398694 scopus 로고    scopus 로고
    • Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: An update of Radiation Therapy Oncology Group Trial (RTOG) 90-01
    • DOI 10.1200/JCO.2004.07.197
    • Eifel PJ, Winter K, Morris M, et al. Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: an update of radiation therapy oncology group trial (RTOG) 90-01. J Clin Oncol 2004;22:872-880. (Pubitemid 41103599)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.5 , pp. 872-880
    • Eifel, P.J.1    Winter, K.2    Morris, M.3    Levenback, C.4    Grigsby, P.W.5    Cooper, J.6    Rotman, M.7    Gershenson, D.8    Mutch, D.G.9
  • 3
    • 32944470177 scopus 로고    scopus 로고
    • Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix
    • Green J, Kirwan J, Tierney J, et al. Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix. Cochrane Database Syst Rev 2005; CD002225.
    • (2005) Cochrane Database Syst Rev
    • Green, J.1    Kirwan, J.2    Tierney, J.3
  • 4
    • 12144290754 scopus 로고    scopus 로고
    • Synchronous Coexpression of Epidermal Growth Factor Receptor and Cyclooxygenase-2 in Carcinomas of the Uterine Cervix: A Potential Predictor of Poor Survival
    • DOI 10.1158/1078-0432.CCR-0497-03
    • Kim GE, Kim YB, Cho NH, et al. Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival. Clin Cancer Res 2004;10:1366-1374. (Pubitemid 38365230)
    • (2004) Clinical Cancer Research , vol.10 , Issue.4 , pp. 1366-1374
    • Kim, G.E.1    Kim, Y.B.2    Cho, N.H.3    Chung, H.-C.4    Pyo, H.R.5    Lee, J.D.6    Park, T.K.7    Koom, W.S.8    Chun, M.9    Suh, C.O.10
  • 5
    • 0034485637 scopus 로고    scopus 로고
    • Detection of epidermal growth factor receptor in the serum of patients with cervical carcinoma
    • Oh MJ, Choi JH, Kim IH, et al. Detection of epidermal growth factor receptor in the serum of patients with cervical carcinoma. Clin Cancer Res 2000;6: 4760-4763.
    • (2000) Clin Cancer Res , vol.6 , pp. 4760-4763
    • Oh, M.J.1    Choi, J.H.2    Kim, I.H.3
  • 6
    • 0033668390 scopus 로고    scopus 로고
    • Cervical epidermal growth factor-receptor (EGF-R) and serum insulin-like growth factor II (IGF-II) levels are potential markers for cervical cancer
    • Mathur SP, Mathur RS, Young RC. Cervical epidermal growth factor-receptor (EGF-R) and serum insulin-like growth factor II (IGF-II) levels are potential markers for cervical cancer. Am J Reprod Immunol 2000;44: 222-230.
    • (2000) Am J Reprod Immunol , vol.44 , pp. 222-230
    • Mathur, S.P.1    Mathur, R.S.2    Young, R.C.3
  • 7
    • 33846202907 scopus 로고    scopus 로고
    • Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs
    • DOI 10.1158/1078-0432.CCR-06-0646
    • Ono M, Kuwano M. Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs. Clin Cancer Res 2006;12:7242-7251. (Pubitemid 46095395)
    • (2006) Clinical Cancer Research , vol.12 , Issue.24 , pp. 7242-7251
    • Ono, M.1    Kuwano, M.2
  • 8
    • 33646418733 scopus 로고    scopus 로고
    • Cetuximab approved by FDA for treatment of head and neck squamous cell cancer
    • Cetuximab approved by FDA for treatment of head and neck squamous cell cancer. Cancer Biol Ther 2006;5: 340-342.
    • (2006) Cancer Biol Ther , vol.5 , pp. 340-342
  • 9
    • 69349094274 scopus 로고    scopus 로고
    • FDA narrows drug label usage
    • Dolgin E. FDA narrows drug label usage. Nature 2009;460:1069.
    • (2009) Nature , vol.460 , pp. 1069
    • Dolgin, E.1
  • 12
    • 33846218204 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mediated signal transduction in the development and therapy of gliomas
    • DOI 10.1158/1078-0432.CCR-06-0874
    • Nicholas MK, Lukas RV, Jafri NF, et al. Epidermal growth factor receptor-mediated signal transduction in the development and therapy of gliomas. Clin Cancer Res 2006;12:7261-7270. (Pubitemid 46095397)
    • (2006) Clinical Cancer Research , vol.12 , Issue.24 , pp. 7261-7270
    • Nicholas, M.K.1    Lukas, R.V.2    Jafri, N.F.3    Faoro, L.4    Salgia, R.5
  • 13
    • 33846244217 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation: How exon19 and 21 mutations changed our understanding of the pathway
    • DOI 10.1158/1078-0432.CCR-06-0627
    • Rosell R, Taron M, Reguart N, et al. Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway. Clin Cancer Res 2006;12:7222-7231. (Pubitemid 46095393)
    • (2006) Clinical Cancer Research , vol.12 , Issue.24 , pp. 7222-7231
    • Rosell, R.1    Taron, M.2    Reguart, N.3    Isla, D.4    Moran, T.5
  • 14
    • 50149118998 scopus 로고    scopus 로고
    • Update on novel therapeutic agents for cervical cancer
    • Del Campo JM, Prat A, Gil-Moreno A, et al. Update on novel therapeutic agents for cervical cancer. Gynecol Oncol 2008;110:S72-S76.
    • (2008) Gynecol Oncol , vol.110
    • Del Campo, J.M.1    Prat, A.2    Gil-Moreno, A.3
  • 16
    • 73149105764 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor (EGFR) and activated EGFR predict poor response to (chemo)r-adiation and survival in cervical cancer
    • Noordhuis MG, Eijsink JJ, Ten Hoor KA, et al. Expression of epidermal growth factor receptor (EGFR) and activated EGFR predict poor response to (chemo)r-adiation and survival in cervical cancer. Clin Cancer Res 2009;15:7389-7397.
    • (2009) Clin Cancer Res , vol.15 , pp. 7389-7397
    • Noordhuis, M.G.1    Eijsink, J.J.2    Ten Hoor, K.A.3
  • 20
    • 59549098296 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein
    • McLaughlin-Drubin ME, Münger K. The human papillomavirus E7 oncoprotein. Virology 2009;384: 335-344.
    • (2009) Virology , vol.384 , pp. 335-344
    • McLaughlin-Drubin, M.E.1    Münger, K.2
  • 21
    • 0028141447 scopus 로고
    • Increased levels and constitutive tyrosine phosphorylation of the epidermal growth factor receptor contribute to autonomous growth of human papillomavirus type 16 immortalized human keratinocytes
    • Zyzak LL, MacDonald LM, Batova A, et al. Increased levels and constitutive tyrosine phosphorylation of the epidermal growth factor receptor contribute to autonomous growth of human papillomavirus type 16 immortalized human keratinocytes. Cell Growth Differ 1994;5:537-547. (Pubitemid 24251406)
    • (1994) Cell Growth and Differentiation , vol.5 , Issue.5 , pp. 537-547
    • Zyzak, L.L.1    MacDonald, L.M.2    Batova, A.3    Forand, R.4    Creek, K.E.5    Pirisi, L.6
  • 22
    • 17844396023 scopus 로고    scopus 로고
    • HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes
    • DOI 10.1038/sj.onc.1208453
    • Zhang B, Srirangam A, Potter DA, et al. HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes. Onco-gene 2005;24:2585-2588. (Pubitemid 40593050)
    • (2005) Oncogene , vol.24 , Issue.15 , pp. 2585-2588
    • Zhang, B.1    Srirangam, A.2    Potter, D.A.3    Roman, A.4
  • 23
    • 0035328577 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes
    • Akerman GS, Tolleson WH, Brown KL, et al. Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes. Cancer Res 2001;61: 3837-3843. (Pubitemid 32695001)
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3837-3843
    • Akerman, G.S.1    Tolleson, W.H.2    Brown, K.L.3    Zyzak, L.L.4    Mourateva, E.5    Engin, T.S.W.6    Basaraba, A.7    Coker, A.L.8    Creek, K.E.9    Pirisi, L.10
  • 25
    • 0036772195 scopus 로고    scopus 로고
    • Detection of three common translocation breakpoints in non-Hodgkin's lymphomas by fluorescence in situ hybridization on routine paraffin-embedded tissue sections
    • DOI 10.1002/path.1197
    • Haralambieva E, Kleiverda K, Mason DY, et al. Detection of three common translocation breakpoints in non-Hodgkin's lymphomas by fluorescence in situ hybridization on routine paraffin-embedded tissue sections. J Pathol 2002;198:163-170. (Pubitemid 35243874)
    • (2002) Journal of Pathology , vol.198 , Issue.2 , pp. 163-170
    • Haralambieva, E.1    Kleiverda, K.2    Mason, D.Y.3    Schuuring, E.4    Kluin, P.M.5
  • 26
    • 0023064191 scopus 로고
    • Genomic organization of alpha satellite DNA on human chromosome 7: Evidence for two distinct alphoid domains on a single chromosome
    • Waye JS, England SB, Willard HF. Genomic organization of alpha satellite DNA on human chromosome 7: evidence for two distinct alphoid domains on a single chromosome. Mol Cell Biol 1987;7:349-356. (Pubitemid 17230417)
    • (1987) Molecular and Cellular Biology , vol.7 , Issue.1 , pp. 349-356
    • Waye, J.S.1    England, S.B.2    Willard, H.F.3
  • 28
    • 33846283823 scopus 로고    scopus 로고
    • High human papillomavirus oncogene mRNA expression and not viral DNA load is associated with poor prognosis in cervical cancer patients
    • DOI 10.1158/1078-0432.CCR-06-1568
    • de Boer MA, Jordanova ES, Kenter GG, et al. High human papillomavirus oncogene mRNA expression and not viral DNA load is associated with poor prognosis in cervical cancer patients. Clin Cancer Res 2007;13:132-138. (Pubitemid 46121861)
    • (2007) Clinical Cancer Research , vol.13 , Issue.1 , pp. 132-138
    • De Boer, M.A.1    Jordanova, E.S.2    Kenter, G.G.3    Peters, A.A.4    Corver, W.E.5    Trimbos, J.B.6    Fleuren, G.J.7
  • 29
    • 42249098858 scopus 로고    scopus 로고
    • Genes involved in cell adhesion, cell motility and mitogenic signaling are altered due to HPV 16 E5 protein expression
    • DOI 10.1038/sj.onc.1210916, PII 1210916
    • Kivi N, Greco D, Auvinen P, et al. Genes involved in cell adhesion, cell motility and mitogenic signaling are altered due to HPV 16 E5 protein expression. Onco-gene 2008;27:2532-2541. (Pubitemid 351550881)
    • (2008) Oncogene , vol.27 , Issue.18 , pp. 2532-2541
    • Kivi, N.1    Greco, D.2    Auvinen, P.3    Auvinen, E.4
  • 30
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034 (online article)
    • Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3:RESEARCH0034 (online article).
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3
  • 32
    • 1842477822 scopus 로고    scopus 로고
    • Expression of HER2neu (c-erbB-2) and epidermal growth factor receptor in cervical cancer: Prognostic correlation with clinical characteristics, and comparison of manual and automated imaging analysis
    • DOI 10.1016/j.ygyno.2004.01.006, PII S009082580400006X
    • Lee CM, Lee RJ, Hammond E, et al. Expression of HER2neu (c-erbB-2) and epidermal growth factor receptor in cervical cancer: prognostic correlation with clinical characteristics, and comparison of manual and automated imaging analysis. Gynecol Oncol 2004;93: 209-214. (Pubitemid 38429572)
    • (2004) Gynecologic Oncology , vol.93 , Issue.1 , pp. 209-214
    • Lee, C.M.1    Lee, R.J.2    Hammond, E.3    Tsodikov, A.4    Dodson, M.5    Zempolich, K.6    Gaffney, D.K.7
  • 33
    • 33846187218 scopus 로고    scopus 로고
    • Update on epidermal growth factor receptor mutations in non-small cell lung cancer
    • DOI 10.1158/1078-0432.CCR-06-0658
    • Riely GJ, Politi KA, Miller VA, et al. Update on epidermal growth factor receptor mutations in non-small cell lung cancer. Clin Cancer Res 2006;12: 7232-7241. (Pubitemid 46095394)
    • (2006) Clinical Cancer Research , vol.12 , Issue.24 , pp. 7232-7241
    • Riely, G.J.1    Politi, K.A.2    Miller, V.A.3    Pao, W.4
  • 34
    • 65449131740 scopus 로고    scopus 로고
    • The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas
    • Kong CS, Narasimhan B, Cao H, et al. The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 2009;74:553-561.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 553-561
    • Kong, C.S.1    Narasimhan, B.2    Cao, H.3
  • 36
    • 0034947649 scopus 로고    scopus 로고
    • EGF mutant receptor vIII as a molecular target in cancer therapy
    • DOI 10.1677/erc.0.0080083
    • Kuan CT, Wikstrand CJ, Bigner DD. EGF mutant receptor vIII as a molecular target in cancer therapy. Endocr Relat Cancer 2001;8:83-96. (Pubitemid 32641351)
    • (2001) Endocrine-Related Cancer , vol.8 , Issue.2 , pp. 83-96
    • Kuan, C.-T.1    Wikstrand, C.J.2    Bigner, D.D.3
  • 38
    • 0029806101 scopus 로고    scopus 로고
    • E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasive phenotype of human papilloma virus- transfected keratinocytes
    • Wilding J, Vousden KH, Soutter WP, et al. E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasive phenotype of human papilloma virus-transfected keratinocytes. Cancer Res 1996;56:5285-5292. (Pubitemid 26383049)
    • (1996) Cancer Research , vol.56 , Issue.22 , pp. 5285-5292
    • Wilding, J.1    Vousden, K.H.2    Soutter, W.P.3    McCrea, P.D.4    Del Buono, R.5    Pignatelli, M.6
  • 40
    • 47549117378 scopus 로고    scopus 로고
    • Loss of p53 induces epidermal growth factor receptor promoter activity in normal human keratinocytes
    • DOI 10.1038/onc.2008.65, PII ONC200865
    • Bheda A, Creek KE, Pirisi L. Loss of p53 induces epidermal growth factor receptor promoter activity in normal human keratinocytes. Oncogene 2008;27: 4315-4323. (Pubitemid 352009996)
    • (2008) Oncogene , vol.27 , Issue.31 , pp. 4315-4323
    • Bheda, A.1    Creek, K.E.2    Pirisi, L.3
  • 41
    • 23044448002 scopus 로고    scopus 로고
    • Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene
    • DOI 10.1158/0008-5472.CAN-05-0083
    • Genther Williams SM, Disbrow GL, Schlegel R, et al. Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papil-lomavirus oncogene. Cancer Res 2005;65:6534-6542. (Pubitemid 41060688)
    • (2005) Cancer Research , vol.65 , Issue.15 , pp. 6534-6542
    • Genther Williams, S.M.1    Disbrow, G.L.2    Schlegel, R.3    Lee, D.4    Threadgill, D.W.5    Lambert, P.F.6


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