Fetal MBL2 haplotypes combined with viral exposure are associated with adverse pregnancy outcomes

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 24, Issue 6, 2011, Pages 847-854

  Gibson, Catherine S ^a,b   MacLennan, Alastair H ^a   Haan, Eric A ^c,d   Priest, Kevin ^e   Dekker, Gustaaf A ^a  

^a North Adelaide SA   (United States)

^b WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d South Australian Clinical Genetics Service   (Australia)

^e DEPARTMENT OF HEALTH   (Australia)

Author keywords

antepartum hemorrhage; Fetal MBL2 haplotype; pregnancy induced hypertension; preterm birth; small for gestational age

Indexed keywords

DNA; MANNOSE BINDING LECTIN 2;

ANTEPARTUM HEMORRHAGE; ARTICLE; BIRTH WEIGHT; CASE CONTROL STUDY; CEREBRAL PALSY; CONTROLLED STUDY; EXPOSURE; FEMALE; GENE; GENETIC POLYMORPHISM; GENETIC SCREENING; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; MBL2 GENE; NEWBORN SCREENING; NONHUMAN; PATHOGENESIS; PREGNANCY COMPLICATION; PREGNANCY OUTCOME; PREMATURITY; PRIORITY JOURNAL; SMALL FOR DATE INFANT; VIRUS INFECTION;

CASE-CONTROL STUDIES; DISEASE SUSCEPTIBILITY; FEMALE; FETUS; HAPLOTYPES; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; MANNOSE-BINDING LECTIN; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANCY OUTCOME; PRENATAL EXPOSURE DELAYED EFFECTS; RISK FACTORS; VIRUS DISEASES;

EID: 79955571263     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2010.531324     Document Type: Article

References (32)

1. Kujovich JL. Thrombophilia and pregnancy complications. Am J Obstet Gynecol 2004;191:412-424. (Pubitemid 39178692)
2. Ozdemir O, Dinleyici EC, Tekin N, Colak O, Aksit MA. Low-mannose-binding lectin levels in susceptibility to neonatal sepsis in preterm neonates with fetal inflammatory response syndrome. J Matern Fetal Neonatal Med 2010;Early Online, 1-5.
3. Malhotra R, Willis AC, Lopez Bernal A, Thiel S, Sim RB. Mannan-binding protein levels in human amniotic fluid during gestation and its interaction with collectin receptor from amnion cells. Immunology 1994;82:439-444. (Pubitemid 24251628)
4. Petersen SV, Thiel S, Jensen L, Vorup-Jensen T, Koch C, Jensenius JC. Control of the classical and the MBL pathway of complement activation. Mol Immunol 2000; 37:803-811.
5. Matsushita M, Hijikata M, Ohta Y, Iwata K, Matsumoto M, Nakao K, Kanai K, Yoshida N, Baba K, Mishiro S. Hepatitis C virus infection and mutations of mannose-binding lectin gene MBL. Arch Virol 1998;143:645-651. (Pubitemid 28229041)
6. Mullighan CG, Marshall SE, Welsh KI. Mannose binding lectin polymorphisms are associated with early age of disease onset and autoimmunity in common variable immunodeficiency. Scand J Immunol 2000;51:111-122. (Pubitemid 30095756)
7. Madsen HO, Garred P, Thiel S, Kurtzhals JA, Lamm LU, Ryder LP, Svejgaard A. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 1995;155:3013-3020.
8. Turner MW, Hamvas RM. Mannose-binding lectin: structure, function, genetics and disease associations. Rev Immunogenet 2000;2:305-322. (Pubitemid 32041159)
9. Gibson CS, MacLennan AH, Goldwater PN, Haan EA, Priest K, Dekker GA. Neurotropic viruses and cerebral palsy: population based case-control study. BMJ 2006;332: 76-80.
10. Srinivas SK, Ma Y, Sammel MD, Chou D, McGrath C, Parry S, Elovitz MA. Placental inflammation and viral infection are implicated in second trimester pregnancy loss. Am J Obstet Gynecol 2006;195:797-802. (Pubitemid 44292126)
11. Gibson CS, Goldwater PN, MacLennan AH, Haan EA, Priest K, Dekker GA. Fetal exposure to herpesviruses may be associated with pregnancy-induced hypertensive disorders and preterm birth in a Caucasian population. BJOG 2008;115: 492-500. (Pubitemid 351225160)
12. Goldenberg RL, Culhane JF, Johnson DC. Maternal infection and adverse fetal and neonatal outcomes. Clin Perinatol 2005;32:523-559. (Pubitemid 41111990)
13. Reddy UM, Baschat AA, Zlatnik MG, Towbin JA, Harman CR, Weiner CP. Detection of viral deoxyribonucleic acid in amniotic fluid: association with fetal malformation and pregnancy abnormalities. Fetal Diagn Ther 2005;20:203-207. (Pubitemid 40591550)
14. Gibson CS, MacLennan AH, Goldwater PN, Haan EA, Priest K, Dekker GA. Mannose-binding lectin haplotypes may be associated with cerebral palsy only after perinatal viral exposure. Am J Obstet Gynecol 2008;198:509.e1-509.e8.
15. Girardi G, Yarilin D, Thurman JM, Holers VM, Salmon JE. Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction. J Exp Med 2006;203:2165-2175. (Pubitemid 44352237)
16. Girardi G. Complement inhibition keeps mothers calm and avoids fetal rejection. Immunol Invest 2008;37:645-659.
17. Gibson CS, Maclennan AH, Hague WM, Haan EA, Priest K, Chan A, Dekker GA. Associations between inherited thrombophilias, gestational age, and cerebral palsy. Am J Obstet Gynecol 2005;193:1437e1-1437e12.
18. Gibson CS, MacLennan AH, Janssen NG, Kist WJ, Hague WM, Haan EA, Goldwater PN, Priest K, Dekker GA. Associations between fetal inherited thrombophilia and adverse pregnancy outcomes. Am J Obstet Gynecol 2006; 194:947e1-947e10.
19. Roberts CL, Lancaster PA. Australian national birthweight percentiles by gestational age. Med J Aust 1999;170:114-118. (Pubitemid 29060342)
20. Lowe SA, Brown MA, Dekker GA, Gatt S, McLintock CK, McMahon LP, Mangos G, Moore MP, Muller P, Paech M, et al. Guidelines for the management of hypertensive disorders of pregnancy 2008. Aust N Z J Obstet Gynaecol 2009;49:242-246.
21. McLean A, Scott J, Keane RJ, Sage L, Chan A. Validation of the 1994 South Australian perinatal data collection form. Adelaide: Pregnancy Outcome Unit, Department of Human Services; 2001.
22. Caggana M, Conroy JM, Pass KA. Rapid, efficient method for multiplex amplification from filter paper. Hum Mutat 1998; 11:404-409. (Pubitemid 28196641)
23. Jack D, Bidwell J, Turner M, Wood N. Simultaneous genotyping for all three known structural mutations in the human mannose-binding lectin gene. Hum Mutat 1997;9:41-46. (Pubitemid 27024030)
24. Turner MW, Dinan L, Heatley S, Jack DL, Boettcher B, Lester S, McCluskey J, Roberton D. Restricted polymorphism of the mannose-binding lectin gene of indigenous Australians. Hum Mol Genet 2000;9:1481-1486. (Pubitemid 30386702)
25. Park KS, Min K, Nam JH, Bang D, Lee ES, Lee S. Association of HYPA haplotype in the mannose-binding lectin gene-2 with Behcet's disease. Tissue Antigens 2005; 65:260-265. (Pubitemid 40342432)
26. Djukic M, Gibson CS, MacLennan AH, Goldwater PN, Haan EA, McMichael G, Priest K, Dekker GA, Hague WM, Chan A, et al. Genetic susceptibility to viral exposure may increase the risk of cerebral palsy. Aust N Z J Obstet Gynaecol 2009; 49:247-253.
27. McMichael GL, Gibson CS, Goldwater PN, Haan EA, Priest K, Dekker GA, MacLennan AH. Association between Apolipoprotein E genotype and cerebral palsy is not confirmed in a Caucasian population. Hum Genet 2008;124:411-416.
28. Girardi G, Bulla R, Salmon JE, Tedesco F. The complement system in the pathophysiology of pregnancy. Mol Immunol 2006;43:68-77. (Pubitemid 41021523)
29. Fisher S, Genbacev O, Maidji E, Pereira L. Human cytomegalovirus infection of placental cytotrophoblasts in vitro and in utero: implications for transmission and pathogenesis. J Virol 2000;74:6808-6820. (Pubitemid 30470664)
30. Maidji E, Percivalle E, Gerna G, Fisher S, Pereira L. Transmission of human cytomegalovirus from infected uterine microvascular endothelial cells to differentiating/ invasive placental cytotrophoblasts. Virology 2002;304:53-69. (Pubitemid 36062832)
31. Edwards DRV, Romero R, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Erez O, Chaiworapongsa T, Pearce BD, et al. Polymorphisms in maternal and fetal genes encoding for proteins involved in extracellular matrix metabolism alter the risk for small-for-gestational age. J Matern Fetal Neonatal Med 2010; Early Online: 1-19.
32. Romero R, Gomez R, Ghezzi F, Yoon BH, Mazor M, Edwin SS, Berry SM. A fetal systemic inflammatory response is followed by the spontaneous onset of preterm parturition. Am J Obstet Gynecol 1998;179:186-193. (Pubitemid 28394494)