Sunitinib improves chemotherapeutic efficacy and ameliorates cisplatin-induced nephrotoxicity in experimental animals

Cancer Chemotherapy and Pharmacology

Volumn 67, Issue 5, 2011, Pages 1035-1044

  Suddek, Ghada M ^a  

^a MANSOURA UNIVERSITY   (Egypt)

Author keywords

Angiogenesis; Cisplatin; Ehrlich ascites carcinoma (EAC); Nephrotoxicity; Sunitinib; Vascular endothelial growth factor (VEGF)

Indexed keywords

ANGIOGENESIS INHIBITOR; CISPLATIN; CREATININE; GLUTATHIONE; MALONALDEHYDE; PROTEIN TYROSINE KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SUNITINIB; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; EHRLICH ASCITES TUMOR CELL; EXPERIMENTAL ANIMAL; FEMALE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY DISTAL TUBULE; KIDNEY FUNCTION; KIDNEY MASS; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE NECROSIS; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SOLID TUMOR; SURVIVAL; UREA NITROGEN BLOOD LEVEL; WEIGHT REDUCTION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; BODY WEIGHT; CARCINOMA, EHRLICH TUMOR; CELL LINE, TUMOR; CISPLATIN; DRUG SYNERGISM; FEMALE; INDOLES; KIDNEY; MALE; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; ORGAN SIZE; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; TUMOR BURDEN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79955564358     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1402-1     Document Type: Article

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