Retrovirus mediated hematopoietic gene therapy: A European regulatory perspective with special focus on the situation in Germany

Cellular Therapy and Transplantation

Volumn 1, Issue 4, 2010, Pages 84-92

  Voelkel, Christine ^a,b   Lührmann, Anke ^b   Baum, Christopher ^a,c   von der Leyen, Heiko E ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Hannover Clinical Trial Center GmbH   (Germany)

^c CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

Author keywords

Clinical trials; Gene therapy; Regulatory framework; Retrovirus

Indexed keywords

DNA; DOUBLE STRANDED DNA;

ADENOVIRUS; ARTICLE; CARCINOGENICITY; CLINICAL DEVELOPMENT PLAN; DNA MODIFICATION; GENE EXPRESSION REGULATION; GENE LOCUS; GENE MUTATION; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC DISORDER; GENOTOXICITY; GERMANY; GOOD MANUFACTURING PRACTICE; HUMAN; LONG TERMINAL REPEAT; NONHUMAN; REGULATOR GENE; RETROVIRUS; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM; X LINKED SEVERE COMBINED IMMUNODEFICIENCY;

EID: 79955563296     PISSN: 1867416X     EISSN: 18668836     Source Type: Journal    
DOI: 10.3205/ctt-2009-en-000044.01     Document Type: Article

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