PDT-induced inflammatory and host responses

Photochemical and Photobiological Sciences

Volumn 10, Issue 5, 2011, Pages 653-663

  Firczuk, Małgorzata ^a   Nowis, Dominika ^a   Gołb, Jakub ^a,b  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b POLISH ACADEMY OF SCIENCES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79955558065     PISSN: 1474905X     EISSN: 14749092     Source Type: Journal    
DOI: 10.1039/c0pp00308e     Document Type: Review

References (99)

1. A. P. Castano P. Mroz M. R. Hamblin Photodynamic therapy and anti-tumour immunity Nat. Rev. Cancer 2006 6 535 545 (Pubitemid 43980542)
2. D. Nowis T. Stoklosa M. Legat T. Issat M. Jakobisiak J. Golab The influence of photodynamic therapy on the immune response Photodiagn. Photodyn. Ther. 2005 2 283 298 (Pubitemid 43061346)
3. T. J. Dougherty C. J. Gomer B. W. Henderson G. Jori D. Kessel M. Korbelik J. Moan Q. Peng Photodynamic therapy J. Natl. Cancer Inst. 1998 90 889 905 (Pubitemid 28304157)
4. D. E. Dolmans D. Fukumura R. K. Jain Photodynamic therapy for cancer Nat. Rev. Cancer 2003 3 380 387 (Pubitemid 37328858)
5. B. W. Henderson S. M. Waldow T. S. Mang W. R. Potter P. B. Malone T. J. Dougherty Tumor destruction and kinetics of tumor cell death in two experimental mouse tumors following photodynamic therapy Cancer Res. 1985 45 572 576 (Pubitemid 15161049)
6. M. Korbelik G. Krosl Photofrin accumulation in malignant and host cell populations of a murine fibrosarcoma Photochem. Photobiol. 1995 62 162 168
7. M. Korbelik G. Krosl Accumulation of benzoporphyrin derivative in malignant and host cell populations of the murine RIF tumor Cancer Lett. 1995 97 249 254
8. D. W. Hunt H. J. Jiang J. G. Levy A. H. Chan Sensitivity of activated murine peritoneal macrophages to photodynamic killing with benzoporphyrin derivative Photochem. Photobiol. 1995 61 417 421
9. E. A. Hryhorenko K. Rittenhouse-Diakun N. S. Harvey J. Morgan C. C. Stewart A. R. Oseroff Characterization of endogenous protoporphyrin IX induced by delta-aminolevulinic acid in resting and activated peripheral blood lymphocytes by four-color flow cytometry Photochem. Photobiol. 1998 67 565 572 (Pubitemid 128472282)
10. C. M. West D. C. West S. Kumar J. V. Moore A comparison of the sensitivity to photodynamic treatment of endothelial and tumour cells in different proliferative states Int. J. Radiat. Biol. 1990 58 145 156 (Pubitemid 20216900)
11. D. Nowis M. Makowski T. Stoklosa M. Legat T. Issat J. Golab Direct tumor damage mechanisms of photodynamic therapy Acta Biochim. Pol. 2005 52 339 352 (Pubitemid 41133769)
12. A. W. Girotti Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects, and cytoprotective mechanisms J. Photochem. Photobiol., B 2001 63 103 113 (Pubitemid 33040728)
13. E. Buytaert M. Dewaele P. Agostinis Molecular effectors of multiple cell death pathways initiated by photodynamic therapy Biochim. Biophys. Acta 2007 1776 86 107 (Pubitemid 47332075)
14. A. Wright W. A. Bubb C. L. Hawkins M. J. Davies Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues Photochem. Photobiol. 2002 76 35 46
15. V. V. Agon W. A. Bubb A. Wright C. L. Hawkins M. J. Davies Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides Free Radical Biol. Med. 2006 40 698 710 (Pubitemid 43170822)
16. N. Ahmad K. Kalka H. Mukhtar In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy Oncogene 2001 20 2314 2317 (Pubitemid 32531289)
17. L. Y. Xue S. M. Chiu N. L. Oleinick Photochemical destruction of the Bcl-2 oncoprotein during photodynamic therapy with the phthalocyanine photosensitizer Pc 4 Oncogene 2001 20 3420 3427 (Pubitemid 32588990)
18. W. Liu A. R. Oseroff H. Baumann Photodynamic therapy causes cross-linking of signal transducer and activator of transcription proteins and attenuation of interleukin-6 cytokine responsiveness in epithelial cells Cancer Res. 2004 64 6579 6587 (Pubitemid 39297917)
19. B. Magi A. Ettorre S. Liberatori L. Bini M. Andreassi S. Frosali P. Neri V. Pallini A. Di Stefano Selectivity of protein carbonylation in the apoptotic response to oxidative stress associated with photodynamic therapy: a cell biochemical and proteomic investigation Cell Death Differ. 2004 11 842 852 (Pubitemid 39139743)
20. T. W. Wong E. Tracy A. R. Oseroff H. Baumann Photodynamic therapy mediates immediate loss of cellular responsiveness to cytokines and growth factors Cancer Res. 2003 63 3812 3818 (Pubitemid 36793071)
21. L. H. Wei H. Baumann E. Tracy Y. Wang A. Hutson S. Rose-John B. W. Henderson Interleukin-6 trans signalling enhances photodynamic therapy by modulating cell cycling Br. J. Cancer 2007 97 1513 1522 (Pubitemid 350175857)
22. A. Szokalska M. Makowski D. Nowis G. M. Wilczynski M. Kujawa C. Wojcik I. Mlynarczuk-Bialy P. Salwa J. Bil S. Janowska P. Agostinis T. Verfaillie M. Bugajski J. Gietka T. Issat E. Glodkowska P. Mrowka T. Stoklosa M. R. Hamblin P. Mroz M. Jakobisiak J. Golab Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of endoplasmic reticulum stress and unfolded protein response Cancer Res. 2009 69 4235 4243
23. F. Martinon X. Chen A. H. Lee L. H. Glimcher TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages Nat. Immunol. 2010 11 411 418
24. A. Furnkranz N. Leitinger Regulation of inflammatory responses by oxidized phospholipids: structure-function relationships Curr. Pharm. Des. 2004 10 915 921 (Pubitemid 38380069)
25. A. Furnkranz A. Schober V. N. Bochkov P. Bashtrykov G. Kronke A. Kadl B. R. Binder C. Weber N. Leitinger Oxidized phospholipids trigger atherogenic inflammation in murine arteries Arterioscler., Thromb., Vasc. Biol. 2005 25 633 638 (Pubitemid 40315690)
26. D. Kessel M. G. Vicente J. J. Reiners, Jr. Initiation of apoptosis and autophagy by photodynamic therapy Lasers Surg. Med. 2006 38 482 488
27. J. J. Reiners, Jr. P. Agostinis K. Berg N. L. Oleinick D. Kessel Assessing autophagy in the context of photodynamic therapy Autophagy 2010 6 7 18
28. A. D. Garg D. Nowis J. Golab P. Vandenabeele D. V. Krysko P. Agostinis Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamation Biochim. Biophys. Acta 2010 1805 53 71
29. M. Korbelik J. Sun I. Cecic Photodynamic therapy-induced cell surface expression and release of heat shock proteins: relevance for tumor response Cancer Res. 2005 65 1018 1026 (Pubitemid 40216464)
30. F. Zhou D. Xing W. R. Chen Regulation of HSP70 on activating macrophages using PDT-induced apoptotic cells Int. J. Cancer 2009 125 1380 1389
31. C. Volanti J. Y. Matroule J. Piette Involvement of oxidative stress in NF-kappaB activation in endothelial cells treated by photodynamic therapy Photochem. Photobiol. 2002 75 36 45
32. J. Sun I. Cecic C. S. Parkins M. Korbelik Neutrophils as inflammatory and immune effectors in photodynamic therapy-treated mouse SCCVII tumours Photochem. Photobiol. Sci. 2002 1 690 695 (Pubitemid 37069785)
33. S. Evans W. Matthews R. Perry D. Fraker J. Norton H. I. Pass Effect of photodynamic therapy on tumor necrosis factor production by murine macrophages J. Natl. Cancer Inst. 1990 82 34 39 (Pubitemid 20020890)
34. N. Yamamoto J. K. Hoober S. Yamamoto Tumoricidal capacities of macrophages photodynamically activated with hematoporphyrin derivative Photochem. Photobiol. 1992 56 245 250
35. N. Yamamoto T. W. Sery J. K. Hoober N. P. Willett D. D. Lindsay Effectiveness of photofrin II in activation of macrophages and in vitro killing of retinoblastoma cells Photochem. Photobiol. 1994 60 160 164 (Pubitemid 2129999)
36. S. Coutier L. Bezdetnaya S. Marchal V. Melnikova I. Belitchenko J. L. Merlin F. Guillemin Foscan (mTHPC) photosensitized macrophage activation: enhancement of phagocytosis, nitric oxide release and tumour necrosis factor-alpha-mediated cytolytic activity Br. J. Cancer 1999 81 37 42 (Pubitemid 29415489)
37. T. N. Demidova M. R. Hamblin Macrophage-targeted photodynamic therapy Int. J. Immunopathol. Pharmacol. 2004 17 117 126 (Pubitemid 39572167)
38. M. O. Obochi L. G. Ratkay J. G. Levy Prolonged skin allograft survival after photodynamic therapy associated with modification of donor skin antigenicity Transplantation 1997 63 810 817 (Pubitemid 27150586)
39. D. E. King H. Jiang G. O. Simkin M. O. Obochi J. G. Levy D. W. Hunt Photodynamic alteration of the surface receptor expression pattern of murine splenic dendritic cells Scand. J. Immunol. 1999 49 184 192 (Pubitemid 29096315)
40. E. A. Hryhorenko A. R. Oseroff J. Morgan K. Rittenhouse-Diakun Antigen specific and nonspecific modulation of the immune response by aminolevulinic acid based photodynamic therapy Immunopharmacology 1998 40 231 240 (Pubitemid 28522181)
41. D. W. Hunt H. Jiang D. J. Granville A. H. Chan S. Leong J. G. Levy Consequences of the photodynamic treatment of resting and activated peripheral T lymphocytes Immunopharmacology 1999 41 31 44 (Pubitemid 29044108)
42. H. Jiang D. J. Granville B. M. McManus J. G. Levy D. W. Hunt Selective depletion of a thymocyte subset in vitro with an immunomodulatory photosensitizer Clin. Immunol. 1999 91 178 187 (Pubitemid 29203417)
43. A. P. Castano P. Mroz M. X. Wu M. R. Hamblin Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model Proc. Natl. Acad. Sci. U. S. A. 2008 105 5495 5500 (Pubitemid 351753891)
44. S. O. Gollnick L. Vaughan B. W. Henderson Generation of effective antitumor vaccines using photodynamic therapy Cancer Res. 2002 62 1604 1608 (Pubitemid 34408477)
45. A. Jalili M. Makowski T. Switaj D. Nowis G. M. Wilczynski E. Wilczek M. Chorazy-Massalska A. Radzikowska W. Maslinski L. Bialy J. Sienko A. Sieron M. Adamek G. Basak P. Mroz I. W. Krasnodebski M. Jakobisiak J. Golab Effective photoimmunotherapy of murine colon carcinoma induced by the combination of photodynamic therapy and dendritic cells Clin. Cancer Res. 2004 10 4498 4508 (Pubitemid 38878894)
46. T. Kushibiki T. Tajiri Y. Tomioka K. Awazu Photodynamic therapy induces interleukin secretion from dendritic cells Int. J. Clin. Exp. Med. 2010 3 110 114
47. M. Korbelik B. Stott J. Sun Photodynamic therapy-generated vaccines: relevance of tumour cell death expression Br. J. Cancer 2007 97 1381 1387 (Pubitemid 350114797)
48. H. Zhang W. Ma Y. Li Generation of effective vaccines against liver cancer by using photodynamic therapy Lasers Med. Sci. 2008 24 549 552
49. S. Karrer A. K. Bosserhoff P. Weiderer M. Landthaler R. M. Szeimies Influence of 5-aminolevulinic acid and red light on collagen metabolism of human dermal fibroblasts J. Invest. Dermatol. 2003 120 325 331 (Pubitemid 36513085)
50. A. Ferrario C. F. Chantrain K. von Tiehl S. Buckley N. Rucker D. R. Shalinsky H. Shimada Y. A. DeClerck C. J. Gomer The matrix metalloproteinase inhibitor prinomastat enhances photodynamic therapy responsiveness in a mouse tumor model Cancer Res. 2004 64 2328 2332 (Pubitemid 38523882)
51. S. Karrer A. K. Bosserhoff P. Weiderer M. Landthaler R. M. Szeimies Keratinocyte-derived cytokines after photodynamic therapy and their paracrine induction of matrix metalloproteinases in fibroblasts Br. J. Dermatol. 2004 151 776 783 (Pubitemid 39482110)
52. E. S. Chu T. K. Wong C. M. Yow Photodynamic effect in medulloblastoma: downregulation of matrix metalloproteinases and human telomerase reverse transcriptase expressions Photochem. Photobiol. Sci. 2008 7 76 83
53. H. Y. Du M. Olivo R. Mahendran Q. Huang H. M. Shen C. N. Ong B. H. Bay Hypericin photoactivation triggers down-regulation of matrix metalloproteinase-9 expression in well-differentiated human nasopharyngeal cancer cells Cell. Mol. Life Sci. 2007 64 979 988 (Pubitemid 46597767)
54. J. Heckenkamp M. Aleksic M. Gawenda S. Breuer J. Brabender A. Mahdavi F. Aydin J. S. Brunkwall Modulation of human adventitial fibroblast function by photodynamic therapy of collagen matrix Eur. J. Vasc. Endovasc. Surg. 2004 28 651 659 (Pubitemid 39462660)
55. P. Margaron R. Sorrenti J. G. Levy Photodynamic therapy inhibits cell adhesion without altering integrin expression Biochim. Biophys. Acta, Mol. Cell Res. 1997 1359 200 210 (Pubitemid 28027118)
56. J. M. Runnels N. Chen B. Ortel D. Kato T. Hasan BPD-MA-mediated photosensitization in vitro and in vivo: cellular adhesion and beta1 integrin expression in ovarian cancer cells Br. J. Cancer 1999 80 946 953 (Pubitemid 29233914)
57. A. Uzdensky A. Juzeniene L. W. Ma J. Moan Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum Biochim. Biophys. Acta, Gen. Subj. 2004 1670 1 11 (Pubitemid 38068358)
58. A. B. Uzdensky A. Juzeniene E. Kolpakova G. O. Hjortland P. Juzenas J. Moan Photosensitization with protoporphyrin IX inhibits attachment of cancer cells to a substratum Biochem. Biophys. Res. Commun. 2004 322 452 457 (Pubitemid 39490325)
59. W. J. de Vree A. N. Fontijne-Dorsman J. F. Koster W. Sluiter Photodynamic treatment of human endothelial cells promotes the adherence of neutrophils in vitro Br. J. Cancer 1996 73 1335 1340 (Pubitemid 26175664)
60. G. Krosl M. Korbelik G. J. Dougherty Induction of immune cell infiltration into murine SCCVII tumour by photofrin-based photodynamic therapy Br. J. Cancer 1995 71 549 555
61. H. W. Lim L. Young M. Hagan I. Gigli Delayed phase of hematoporphyrin- induced phototoxicity: modulation by complement, leukocytes, and antihistamines J. Invest. Dermatol. 1985 84 114 117 (Pubitemid 15158452)
62. I. Cecic M. Korbelik Mediators of peripheral blood neutrophilia induced by photodynamic therapy of solid tumors Cancer Lett. 2002 183 43 51 (Pubitemid 34607350)
63. J. Golab G. Wilczynski R. Zagozdzon T. Stoklosa A. Dabrowska J. Rybczynska M. Wasik E. Machaj T. Olda K. Kozar R. Kaminski A. Giermasz A. Czajka W. Lasek W. Feleszko M. Jakobisiak Potentiation of the anti-tumour effects of Photofrin-based photodynamic therapy by localized treatment with G-CSF Br. J. Cancer 2000 82 1485 1491 (Pubitemid 30175918)
64. I. Cecic C. S. Parkins M. Korbelik Induction of systemic neutrophil response in mice by photodynamic therapy of solid tumors Photochem. Photobiol. 2001 74 712 720
65. S. O. Gollnick S. S. Evans H. Baumann B. Owczarczak P. Maier L. Vaughan W. C. Wang E. Unger B. W. Henderson Role of cytokines in photodynamic therapy-induced local and systemic inflammation Br. J. Cancer 2003 88 1772 1779 (Pubitemid 36760423)
66. C. Fady D. Reisser F. Martin Non-activated rat neutrophils kill syngeneic colon tumor cells by the release of a low molecular weight factor Immunobiology 1990 181 1 12 (Pubitemid 20314134)
67. M. Korbelik I. Cecic Contribution of myeloid and lymphoid host cells to the curative outcome of mouse sarcoma treatment by photodynamic therapy Cancer Lett. 1999 137 91 98 (Pubitemid 29179500)
68. W. J. de Vree M. C. Essers H. S. de Bruijn W. M. Star J. F. Koster W. Sluiter Evidence for an important role of neutrophils in the efficacy of photodynamic therapy in vivo Cancer Res. 1996 56 2908 2911 (Pubitemid 26199729)
69. G. Krosl M. Korbelik J. Krosl G. J. Dougherty Potentiation of photodynamic therapy-elicited antitumor response by localized treatment with granulocyte-macrophage colony-stimulating factor Cancer Res. 1996 56 3281 3286 (Pubitemid 26242977)
70. J. Kolls J. Xie R. LeBlanc T. Malinski S. Nelson W. Summer S. S. Greenberg Rapid induction of messenger RNA for nitric oxide synthase II in rat neutrophils in vivo by endotoxin and its suppression by prednisolone Proc. Soc. Exp. Biol. Med. 1994 205 220 229
71. H. S. de Bruijn W. Sluiter A. Van Der Ploeg-van den Heuvel H. J. Sterenborg D. J. Robinson Evidence for a bystander role of neutrophils in the response to systemic 5-aminolevulinic acid-based photodynamic therapy Photodermatol., Photoimmunol. Photomed. 2006 22 238 246 (Pubitemid 44317157)
72. W. J. de Vree M. C. Essers J. F. Koster W. Sluiter Role of interleukin 1 and granulocyte colony-stimulating factor in photofrin- based photodynamic therapy of rat rhabdomyosarcoma tumors Cancer Res. 1997 57 2555 2558 (Pubitemid 27283755)
73. I. Cecic B. Stott M. Korbelik Acute phase response-associated systemic neutrophil mobilization in mice bearing tumors treated by photodynamic therapy Int. Immunopharmacol. 2006 6 1259 1266 (Pubitemid 43884994)
74. R. C. Brooke A. Sinha M. K. Sidhu R. E. Watson M. K. Church P. S. Friedmann G. F. Clough L. E. Rhodes Histamine is released following aminolevulinic acid-photodynamic therapy of human skin and mediates an aminolevulinic acid dose-related immediate inflammatory response J. Invest. Dermatol. 2006 126 2296 2301 (Pubitemid 44413177)
75. M. Korbelik and I. Cecic, Mechanism of tumor destruction by photodynamic therapy, in Handbook of Photochemistry and Photobiology, ed., H. S. Nalwa,, American Scientific Publishers, Stevenson Ranch (California), 2003, vol. 4, ch. 2, pp. 39-77
76. S. Merchant N. Huang M. Korbelik Expression of complement and pentraxin proteins in acute phase response elicited by tumor photodynamic therapy: The engagement of adrenal hormones Int. Immunopharmacol. 2010 10 1595 1601
77. M. Korbelik V. R. Naraparaju N. Yamamoto Macrophage- directed immunotherapy as adjuvant to photodynamic therapy of cancer Br. J. Cancer 1997 75 202 207 (Pubitemid 27019563)
78. M. Korbelik I. Cecic Enhancement of tumour response to photodynamic therapy by adjuvant mycobacterium cell-wall treatment J. Photochem. Photobiol., B 1998 44 151 158 (Pubitemid 28505179)
79. I. Cecic J. Sun M. Korbelik Role of complement anaphylatoxin C3a in photodynamic therapy-elicited engagement of host neutrophils and other immune cells Photochem. Photobiol. 2006 82 558 562
80. B. Stott M. Korbelik Activation of complement C3, C5, and C9 genes in tumors treated by photodynamic therapy Cancer Immunol. Immunother. 2006 56 649 658
81. M. Korbelik Complement upregulation in photodynamic therapy-treated tumors: Role of Toll- like receptor pathway and NFkappaB Cancer Lett. 2009 281 232 238
82. M. Korbelik I. Cecic Complement activation cascade and its regulation: relevance for the response of solid tumors to photodynamic therapy J. Photochem. Photobiol., B 2008 93 53 59
83. I. Cecic A. I. Minchinton M. Korbelik The impact of complement activation on tumor oxygenation during photodynamic therapy Photochem. Photobiol. 2007 83 1049 1055 (Pubitemid 47438528)
84. M. Korbelik J. Sun I. Cecic K. Serrano Adjuvant treatment for complement activation increases the effectiveness of photodynamic therapy of solid tumors Photochem. Photobiol. Sci. 2004 3 812 816 (Pubitemid 39302983)
85. M. Korbelik P. D. Cooper Potentiation of photodynamic therapy of cancer by complement: the effect of gamma-inulin Br. J. Cancer 2006 96 67 72
86. D. Akramiene G. Grazeliene J. Didziapetriene E. Kevelaitis Treatment of Lewis lung carcinoma by photodynamic therapy and glucan from barley Medicina (Kaunas) 2009 45 480 485
87. D. Akramiene C. Aleksandraviciene G. Grazeliene R. Zalinkevicius K. Suziedelis J. Didziapetriene U. Simonsen E. Stankevicius E. Kevelaitis Potentiating effect of beta-glucans on photodynamic therapy of implanted cancer cells in mice Tohoku J. Exp. Med. 2010 220 299 306
88. M. A. Brantley, Jr. S. L. Edelstein J. M. King M. R. Plotzke R. S. Apte S. M. Kymes A. Shiels Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to photodynamic therapy Eye (London) 2009 23 626 631
89. S. S. Yom T. M. Busch J. S. Friedberg E. P. Wileyto D. Smith E. Glatstein S. M. Hahn Elevated serum cytokine levels in mesothelioma patients who have undergone pleurectomy or extrapleural pneumonectomy and adjuvant intraoperative photodynamic therapy Photochem. Photobiol. 2003 78 75 81
90. D. A. Bellnier Potentiation of photodynamic therapy in mice with recombinant human tumor necrosis factor-alpha J. Photochem. Photobiol., B 1991 8 203 210
91. M. Korbelik PDT-associated host response and its role in the therapy outcome Lasers Surg. Med. 2006 38 500 508
92. T. H. Foster R. S. Murant R. G. Bryant R. S. Knox S. L. Gibson R. Hilf Oxygen consumption and diffusion effects in photodynamic therapy Radiat. Res. 1991 126 296 303
93. S. Iinuma K. T. Schomacker G. Wagnieres M. Rajadhyaksha M. Bamberg T. Momma T. Hasan In vivo fluence rate and fractionation effects on tumor response and photobleaching: photodynamic therapy with two photosensitizers in an orthotopic rat tumor model Cancer Res. 1999 59 6164 6170 (Pubitemid 30035638)
94. T. M. Sitnik B. W. Henderson The effect of fluence rate on tumor and normal tissue responses to photodynamic therapy Photochem. Photobiol. 1998 67 462 466 (Pubitemid 128472703)
95. T. M. Sitnik J. A. Hampton B. W. Henderson Reduction of tumour oxygenation during and after photodynamic therapy in vivo: effects of fluence rate Br. J. Cancer 1998 77 1386 1394 (Pubitemid 28190737)
96. B. W. Henderson S. O. Gollnick J. W. Snyder T. M. Busch P. C. Kousis R. T. Cheney J. Morgan Choice of oxygen-conserving treatment regimen determines the inflammatory response and outcome of photodynamic therapy of tumors Cancer Res. 2004 64 2120 2126 (Pubitemid 38339462)
97. P. C. Kousis B. W. Henderson P. G. Maier S. O. Gollnick Photodynamic therapy enhancement of antitumor immunity is regulated by neutrophils Cancer Res. 2007 67 10501 10510 (Pubitemid 350070826)
98. E. Kabingu A. R. Oseroff G. E. Wilding S. O. Gollnick Enhanced systemic immune reactivity to a Basal cell carcinoma associated antigen following photodynamic therapy Clin. Cancer Res. 2009 15 4460 4466
99. B. W. Henderson T. M. Sitnik-Busch L. A. Vaughan Potentiation of photodynamic therapy antitumor activity in mice by nitric oxide synthase inhibition is fluence rate dependent Photochem. Photobiol. 1999 70 64 71 (Pubitemid 129572616)