The adaptor protein TRADD is essential for TNF-like ligand 1A/death receptor 3 signaling

Journal of Immunology

Volumn 186, Issue 9, 2011, Pages 5212-5216

  Pobezinskaya, Yelena L ^a   Choksi, Swati ^a   Morgan, Michael J ^a   Cao, Xiumei ^a   Liu, Zheng Gang ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; DEATH RECEPTOR 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR LIKE LIGAND 1A; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; ENZYME PHOSPHORYLATION; IMMUNOPRECIPITATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; UBIQUITINATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL SEPARATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; IMMUNOPRECIPITATION; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 25; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15;

EID: 79955539807     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002374     Document Type: Article

References (29)

1. Lavrik, I., A. Golks, and P. H. Krammer. 2005. Death receptor signaling. J. Cell Sci. 118: 265-267.
2. Kitson, J., T. Raven, Y. P. Jiang, D. V. Goeddel, K. M. Giles, K. T. Pun, C. J. Grinham, R. Brown, and S. N. Farrow. 1996. A death-domain-containing receptor that mediates apoptosis. Nature 384: 372-375.
3. Bodmer, J. L., K. Burns, P. Schneider, K. Hofmann, V. Steiner, M. Thome, T. Bornand, M. Hahne, M. Schröter, K. Becker, et al. 1997. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). Immunity 6: 79-88. (Pubitemid 27130217)
4. Chinnaiyan, A. M., K. O'Rourke, G. L. Yu, R. H. Lyons, M. Garg, D. R. Duan, L. Xing, R. Gentz, J. Ni, and V. M. Dixit. 1996. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 274: 990-992.
5. Screaton, G. R., X. N. Xu, A. L. Olsen, A. E. Cowper, R. Tan, A. J. McMichael, and J. I. Bell. 1997. LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing. Proc. Natl. Acad. Sci. USA 94: 4615-4619.
6. Tan, K. B., J. Harrop, M. Reddy, P. Young, J. Terrett, J. Emery, G. Moore, and A. Truneh. 1997. Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells. Gene 204: 35-46. (Pubitemid 28022168)
7. Migone, T. S., J. Zhang, X. Luo, L. Zhuang, C. Chen, B. Hu, J. S.Hong, J.W. Perry, S. F. Chen, J. X. Zhou, et al. 2002. TL1A is a TNF-like ligand for DR3 and TR6/ DcR3 and functions as a T cell costimulator. Immunity 16: 479-492. (Pubitemid 34260924)
8. Bamias, G., C. Martin, III, M. Marini, S. Hoang, M. Mishina, W. G. Ross, M. A. Sachedina, C. M. Friel, J. Mize, S. J. Bickston, et al. 2003. Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease. J. Immunol. 171: 4868-4874. (Pubitemid 37310609)
9. Bamias, G., M. Mishina, M. Nyce, W. G. Ross, G. Kollias, J. Rivera-Nieves, T. T. Pizarro, and F. Cominelli. 2006. Role of TL1A and its receptor DR3 in two models of chronic murine ileitis. Proc. Natl. Acad. Sci. USA 103: 8441-8446.
10. Cassatella, M. A., G. Pereira-da-Silva, I. Tinazzi, F. Facchetti, P. Scapini, F. Calzetti, N. Tamassia, P. Wei, B. Nardelli, V. Roschke, et al. 2007. Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis. [Published erratum appears in 2007 J. Immunol. 179: 1390.] J. Immunol. 178: 7325-7333. (Pubitemid 46847460)
11. Baud, V., and M. Karin. 2001. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 11: 372-377. (Pubitemid 32900529)
12. Chen, G., and D. V. Goeddel. 2002. TNF-R1 signaling: a beautiful pathway. Science 296: 1634-1635.
13. Locksley, R. M., N. Killeen, and M. J. Lenardo. 2001. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104: 487-501.
14. Micheau, O., and J. Tschopp. 2003. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114: 181-190. (Pubitemid 36936912)
15. Yeh, W. C., J. L. Pompa, M. E. McCurrach, H. B. Shu, A. J. Elia, A. Shahinian, M. Ng, A. Wakeham, W. Khoo, K. Mitchell, et al. 1998. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279: 1954-1958. (Pubitemid 28168653)
16. Kelliher, M. A., S. Grimm, Y. Ishida, F. Kuo, B. Z. Stanger, and P. Leder. 1998. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 8: 297-303. (Pubitemid 28188890)
17. Hsu, H., J. Xiong, and D. V. Goeddel. 1995. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 81: 495-504.
18. Pobezinskaya, Y. L., Y. S. Kim, S. Choksi, M. J. Morgan, T. Li, C. Liu, and Z. Liu. 2008. The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors. Nat. Immunol. 9: 1047-1054.
19. Ermolaeva, M. A., M. C. Michallet, N. Papadopoulou, O. Utermöhlen, K. Kranidioti, G. Kollias, J. Tschopp, and M. Pasparakis. 2008. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat. Immunol. 9: 1037-1046.
20. Chen, N. J., I. I. Chio, W. J. Lin, G. Duncan, H. Chau, D. Katz, H. L. Huang, K. A. Pike, Z. Hao, Y. W. Su, et al. 2008. Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. Proc. Natl. Acad. Sci. USA 105: 12429-12434.
21. Varfolomeev, E. E., M. Schuchmann, V. Luria, N. Chiannilkulchai, J. S. Beckmann, I. L. Mett, D. Rebrikov, V. M. Brodianski, O. C. Kemper, O. Kollet, et al. 1998. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9: 267-276.
22. Wen, L., L. Zhuang, X. Luo, and P. Wei. 2003. TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells. J. Biol. Chem. 278: 39251-39258.
23. Meylan, F., T. S. Davidson, E. Kahle, M. Kinder, K. Acharya, D. Jankovic, V. Bundoc, M. Hodges, E. M. Shevach, A. Keane-Myers, et al. 2008. The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases. Immunity 29: 79-89.
24. Wesemann, D. R., H. Qin, N. Kokorina, and E. N. Benveniste. 2004. TRADD interacts with STAT1-alpha and influences interferon-gamma signaling. Nat. Immunol. 5: 199-207.
25. Michallet, M. C., E. Meylan, M. A. Ermolaeva, J. Vazquez, M. Rebsamen, J. Curran, H. Poeck, M. Bscheider, G. Hartmann, M. König, et al. 2008. TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity 28: 651-661.
26. El Yazidi-Belkoura, I., E. Adriaenssens, L. Dollé, S. Descamps, and H. Hondermarck. 2003. Tumor necrosis factor receptor-associated death domain protein is involved in the neurotrophin receptor-mediated antiapoptotic activity of nerve growth factor in breast cancer cells. J. Biol. Chem. 278: 16952-16956.
27. Chaudhary, P. M., M. Eby, A. Jasmin, A. Bookwalter, J. Murray, and L. Hood. 1997. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 7: 821-830. (Pubitemid 28064895)
28. Fang, L., B. Adkins, V. Deyev, and E. R. Podack. 2008. Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation. J. Exp. Med. 205: 1037-1048.
29. Pappu, B. P., A. Borodovsky, T. S. Zheng, X. Yang, P. Wu, X. Dong, S. Weng, B. Browning, M. L. Scott, L. Ma, et al. 2008. TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. J. Exp. Med. 205: 1049-1062.