XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes

Developmental Biology

Volumn 354, Issue 1, 2011, Pages 111-122

  Lavery, Rowena ^a,b   Lardenois, Aurélie ^c   Ranc Jianmotamedi, Fariba ^a,b   Pauper, Eva ^a,b   Gregoire, Elodie P ^a,b   Vigier, Caroline ^a,b   Moreilhon, Chimene ^d,e   Primig, Michael ^c   Chaboissier, Marie Christine ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

^d CNRS   (France)

^e PASTEUR HOSPITAL   (France)

Author keywords

Mouse model; Sex determination; Sex reversal; Sox9; XY oocytes

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR SOX9;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FERTILITY; FERTILIZATION; KARYOTYPE 46,XX; KARYOTYPE 46,XY; LOSS OF FUNCTION MUTATION; MALE; NONHUMAN; OOCYTE; OVARY DEVELOPMENT; OVARY FOLLICLE DEVELOPMENT; PRIORITY JOURNAL; SERTOLI CELL; SEX DIFFERENTIATION; SEX TRANSFORMATION; STEM CELL; TESTIS DEVELOPMENT; TRANSCRIPTION REGULATION;

MAMMALIA;

EID: 79955522467     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2011.03.029     Document Type: Article

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