메뉴 건너뛰기




Volumn 141, Issue 4, 2011, Pages 548-553

Dietary arachidonate differentially alters desaturase-elongase pathway flux and gene expression in liver and intestine of suckling pigs

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE 1; ARACHIDONIC ACID; CARBON 13; ELONGASE; ENZYME; ICOSAPENTAENOIC ACID; UNCLASSIFIED DRUG;

EID: 79955500310     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.110.127118     Document Type: Article
Times cited : (23)

References (37)
  • 1
    • 0026048644 scopus 로고
    • Essential fatty-acids in growth and development
    • Innis SM. Essential fatty-acids in growth and development. Prog Lipid Res. 1991;30:39-103.
    • (1991) Prog Lipid Res , vol.30 , pp. 39-103
    • Innis, S.M.1
  • 2
    • 0035165337 scopus 로고    scopus 로고
    • Metabolism and functions of highly unsaturated fatty acids: an update
    • Nakamura MT, Cho HP, Xu J, Tang ZR, Clarke SD. Metabolism and functions of highly unsaturated fatty acids: an update. Lipids. 2001;36: 961-4.
    • (2001) Lipids , vol.36 , pp. 961-964
    • Nakamura, M.T.1    Cho, H.P.2    Xu, J.3    Tang, Z.R.4    Clarke, S.D.5
  • 5
    • 3142753961 scopus 로고    scopus 로고
    • Structure, function, and dietary regulation of delta 6, delta 5, and delta 9 desaturases
    • Nakamura MT, Nara TY. Structure, function, and dietary regulation of delta 6, delta 5, and delta 9 desaturases. Annu Rev Nutr. 2004;24: 345-76.
    • (2004) Annu Rev Nutr , vol.24 , pp. 345-376
    • Nakamura, M.T.1    Nara, T.Y.2
  • 6
    • 33646018341 scopus 로고    scopus 로고
    • Fatty acid elongases in mammals: their regulation and roles in metabolism
    • Jakobsson A,Westerberg R, Jacobsson A. Fatty acid elongases in mammals: their regulation and roles in metabolism. Prog Lipid Res. 2006;45:237-49.
    • (2006) Prog Lipid Res , vol.45 , pp. 237-249
    • Jakobsson, A.1    Westerberg, R.2    Jacobsson, A.3
  • 7
    • 76749132709 scopus 로고    scopus 로고
    • The key roles of elongases and desaturases in mammalian fatty acid metabolism: insights from transgenic mice
    • Guillou H, Zadravec D, Martin PGP, Jacobsson A. The key roles of elongases and desaturases in mammalian fatty acid metabolism: insights from transgenic mice. Prog Lipid Res. 2010;49:186-99.
    • (2010) Prog Lipid Res , vol.49 , pp. 186-199
    • Guillou, H.1    Zadravec, D.2    Martin, P.G.P.3    Jacobsson, A.4
  • 8
    • 0019313055 scopus 로고
    • Effects of dietary-protein and EFA deficiency on liver delta-5, delta-6 and delta-9 desaturase activities in the early developing rat
    • De Tomas ME, Mercuri O, Rodrigo A. Effects of dietary-protein and EFA deficiency on liver delta-5, delta-6 and delta-9 desaturase activities in the early developing rat. J Nutr. 1980;110:595-9.
    • (1980) J Nutr , vol.110 , pp. 595-599
    • De Tomas, M.E.1    Mercuri, O.2    Rodrigo, A.3
  • 9
    • 0022966366 scopus 로고
    • Modulation of delta-6 and delta-5 rat-liver microsomal desaturase activities by dexamethasoneinduced factor
    • Marra CA, Dealaniz MJT, Brenner RR. Modulation of delta-6 and delta-5 rat-liver microsomal desaturase activities by dexamethasoneinduced factor. Biochim Biophys Acta. 1986;879:388-93.
    • (1986) Biochim Biophys Acta , vol.879 , pp. 388-393
    • Marra, C.A.1    Dealaniz, M.J.T.2    Brenner, R.R.3
  • 10
    • 0033601177 scopus 로고    scopus 로고
    • Cloning, expression, and fatty acid regulation of the human delta-5 desaturase
    • Cho HP, Nakamura M, Clarke SD. Cloning, expression, and fatty acid regulation of the human delta-5 desaturase. J Biol Chem. 1999;274:37335-9.
    • (1999) J Biol Chem , vol.274 , pp. 37335-37339
    • Cho, H.P.1    Nakamura, M.2    Clarke, S.D.3
  • 11
    • 0032929070 scopus 로고    scopus 로고
    • Cloning, expression, and nutritional regulation of the mammalian delta-6 desaturase
    • Cho HP, Nakamura MT, Clarke SD. Cloning, expression, and nutritional regulation of the mammalian delta-6 desaturase. J Biol Chem. 1999; 274:471-7.
    • (1999) J Biol Chem , vol.274 , pp. 471-477
    • Cho, H.P.1    Nakamura, M.T.2    Clarke, S.D.3
  • 14
    • 0002350319 scopus 로고
    • Factors influencing fatty acid chain elongation and desaturation
    • Vergroesen AJ, Crawford M, editors. 2nd ed. San Diego: Academic Press
    • Brenner RR. Factors influencing fatty acid chain elongation and desaturation. In: Vergroesen AJ, Crawford M, editors. The role of fats in human nutrition. 2nd ed. San Diego: Academic Press; 1989. p. 44-79.
    • (1989) The role of fats in human nutrition , pp. 44-79
    • Brenner, R.R.1
  • 16
    • 21744446895 scopus 로고    scopus 로고
    • Tissuespecific, nutritional, and developmental regulation of rat fatty acid elongases
    • Wang Y, Botolin D, Christian B, Busik J, Xu JH, Jump DB. Tissuespecific, nutritional, and developmental regulation of rat fatty acid elongases. J Lipid Res. 2005;46:706-15.
    • (2005) J Lipid Res , vol.46 , pp. 706-715
    • Wang, Y.1    Botolin, D.2    Christian, B.3    Busik, J.4    Xu, J.H.5    Jump, D.B.6
  • 17
    • 50949112066 scopus 로고    scopus 로고
    • Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition
    • Wang Y, Torres-Gonzalez M, Tripathy S, Botolin D, Christian B, Jump DB. Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition. J Lipid Res. 2008;49:1538-52.
    • (2008) J Lipid Res , vol.49 , pp. 1538-1552
    • Wang, Y.1    Torres-Gonzalez, M.2    Tripathy, S.3    Botolin, D.4    Christian, B.5    Jump, D.B.6
  • 18
    • 73949150124 scopus 로고    scopus 로고
    • Control of free arachidonic acid levels by phospholipases A(2) and lysophospholipid acyltransferases
    • Perez-Chacon G, Astudillo AM, Balgoma D, Balboa MA, Balsinde J. Control of free arachidonic acid levels by phospholipases A(2) and lysophospholipid acyltransferases. Biochim Biophys Acta. 2009;1791: 1103-13.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 1103-1113
    • Perez-Chacon, G.1    Astudillo, A.M.2    Balgoma, D.3    Balboa, M.A.4    Balsinde, J.5
  • 19
    • 0034613316 scopus 로고    scopus 로고
    • Fatty acid regulation of gene transcription
    • Duplus E, Glorian M, Forest C. Fatty acid regulation of gene transcription. J Biol Chem. 2000;275:30749-52.
    • (2000) J Biol Chem , vol.275 , pp. 30749-30752
    • Duplus, E.1    Glorian, M.2    Forest, C.3
  • 20
    • 0030611762 scopus 로고    scopus 로고
    • Prostaglandins I-2 and E-2 have a synergistic role in rescuing epithelial barrier function in porcine ileum
    • Blikslager AT, Roberts MC, Rhoads JM, Argenzio RA. Prostaglandins I-2 and E-2 have a synergistic role in rescuing epithelial barrier function in porcine ileum. J Clin Invest. 1997;100:1928-33.
    • (1997) J Clin Invest , vol.100 , pp. 1928-1933
    • Blikslager, A.T.1    Roberts, M.C.2    Rhoads, J.M.3    Argenzio, R.A.4
  • 21
    • 0032946862 scopus 로고    scopus 로고
    • Prostaglandin-induced recovery of barrier function in porcine ileum is triggered by chloride secretion
    • Blikslager AT, Roberts MC, Argenzio RA. Prostaglandin-induced recovery of barrier function in porcine ileum is triggered by chloride secretion. Am J Physiol. 1999;276:G28-36.
    • (1999) Am J Physiol , vol.276
    • Blikslager, A.T.1    Roberts, M.C.2    Argenzio, R.A.3
  • 22
    • 55949134438 scopus 로고    scopus 로고
    • Enrichment of intestinal mucosal phospholipids with arachidonic and eicosapentaenoic acids fed to suckling piglets is dose and time dependent
    • Hess HA, Corl BA, Lin X, Jacobi SK, Harrell RJ, Blikslager AT, Odle J. Enrichment of intestinal mucosal phospholipids with arachidonic and eicosapentaenoic acids fed to suckling piglets is dose and time dependent. J Nutr. 2008;138:2164-71.
    • (2008) J Nutr , vol.138 , pp. 2164-2171
    • Hess, H.A.1    Corl, B.A.2    Lin, X.3    Jacobi, S.K.4    Harrell, R.J.5    Blikslager, A.T.6    Odle, J.7
  • 23
    • 80054077210 scopus 로고    scopus 로고
    • Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs
    • Epub, Jan 7
    • Xi L, Bo J, Mathews-Oliver SA, Corl BA, Jacobi SK, Oliver WT, Harrell RJ, Odle J. Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs. J Nutr Biochem. Epub 2011 Jan 7.
    • (2011) J Nutr Biochem
    • Xi, L.1    Bo, J.2    Mathews-Oliver, S.A.3    Corl, B.A.4    Jacobi, S.K.5    Oliver, W.T.6    Harrell, R.J.7    Odle, J.8
  • 24
    • 0035710229 scopus 로고    scopus 로고
    • An overview of real-time quantitative PCR: applications to quantify cytokine gene expression
    • Giulietti A, Overbergh L, Valckx D, Decallonne B, Bouillon R, Mathieu C. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods. 2001;25:386-401.
    • (2001) Methods , vol.25 , pp. 386-401
    • Giulietti, A.1    Overbergh, L.2    Valckx, D.3    Decallonne, B.4    Bouillon, R.5    Mathieu, C.6
  • 25
    • 0031876308 scopus 로고    scopus 로고
    • Addition of triglycerides with arachidonic acid or docosahexaenoic acid to infant formula has tissue- and lipid class-specific effects on fatty acids and hepatic desaturase activities in formula-fed piglets
    • Presa-Owens S, Innis SM, Rioux FM. Addition of triglycerides with arachidonic acid or docosahexaenoic acid to infant formula has tissue- and lipid class-specific effects on fatty acids and hepatic desaturase activities in formula-fed piglets. J Nutr. 1998;128: 1376-84.
    • (1998) J Nutr , vol.128 , pp. 1376-1384
    • Presa-Owens, S.1    Innis, S.M.2    Rioux, F.M.3
  • 26
    • 0034805897 scopus 로고    scopus 로고
    • Effects of diabetes and insulin on hepatic Delta 6 desaturase gene expression
    • Rimoldi OJ, Finarelli GS, Brenner RR. Effects of diabetes and insulin on hepatic Delta 6 desaturase gene expression. Biochem Biophys Res Commun. 2001;283:323-6.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 323-326
    • Rimoldi, O.J.1    Finarelli, G.S.2    Brenner, R.R.3
  • 27
    • 21044436483 scopus 로고    scopus 로고
    • The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile
    • Mcneil CJ, Finch AM, Page KR, Clarke SD, Ashworth CJ, McArdle HJ. The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile. Reproduction. 2005;129:757-63.
    • (2005) Reproduction , vol.129 , pp. 757-763
    • Mcneil, C.J.1    Finch, A.M.2    Page, K.R.3    Clarke, S.D.4    Ashworth, C.J.5    McArdle, H.J.6
  • 28
    • 19344368219 scopus 로고    scopus 로고
    • Influence of size at birth on the endocrine profiles and expression of uncoupling proteins in subcutaneous adipose tissue, lung, and muscle of neonatal pigs
    • Mostyn A, Litten JC, Perkins KS, Euden PJ, Corson AM, Symonds ME, Clarke L. Influence of size at birth on the endocrine profiles and expression of uncoupling proteins in subcutaneous adipose tissue, lung, and muscle of neonatal pigs. Am J Physiol Regul Integr Comp Physiol. 2005;288:R1536-42.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Mostyn, A.1    Litten, J.C.2    Perkins, K.S.3    Euden, P.J.4    Corson, A.M.5    Symonds, M.E.6    Clarke, L.7
  • 30
    • 0021950269 scopus 로고
    • Synthesis of chain elongationdesaturation products of linoleic-acid by liver and brain microsomes during development of the pig
    • Clandinin MT, Wong K, Hacker RR. Synthesis of chain elongationdesaturation products of linoleic-acid by liver and brain microsomes during development of the pig. Biochem J. 1985;226:305-9.
    • (1985) Biochem J , vol.226 , pp. 305-309
    • Clandinin, M.T.1    Wong, K.2    Hacker, R.R.3
  • 31
    • 0024793383 scopus 로고
    • Utilization of medium-chain triglycerides by neonatal piglets: II. Effects of even- and odd-chain triglyceride consumption over the first 2 days of life on blood metabolites and urinary nitrogen excretion
    • Odle J, Benevenga NJ, Crenshaw TD. Utilization of medium-chain triglycerides by neonatal piglets: II. Effects of even- and odd-chain triglyceride consumption over the first 2 days of life on blood metabolites and urinary nitrogen excretion. J Anim Sci. 1989;67: 3340-51.
    • (1989) J Anim Sci , vol.67 , pp. 3340-3351
    • Odle, J.1    Benevenga, N.J.2    Crenshaw, T.D.3
  • 32
    • 0024266226 scopus 로고
    • The effect of dietary essential fatty-acid deficiency on the composition and properties of the liver microsomal membrane of rats
    • Christon R, Fernandez Y, Cambongros C, Periquet A, Deltour P, Leger CL, Mitjavila S. The effect of dietary essential fatty-acid deficiency on the composition and properties of the liver microsomal membrane of rats. J Nutr. 1988;118:1311-8.
    • (1988) J Nutr , vol.118 , pp. 1311-1318
    • Christon, R.1    Fernandez, Y.2    Cambongros, C.3    Periquet, A.4    Deltour, P.5    Leger, C.L.6    Mitjavila, S.7
  • 33
    • 0021019242 scopus 로고
    • Hepatic fatty-acids and acyl desaturases in rats: effects of dietary carbohydrate and essential fatty-acids
    • De Schrijver R, Privett OS. Hepatic fatty-acids and acyl desaturases in rats: effects of dietary carbohydrate and essential fatty-acids. J Nutr. 1983;113:2217-22.
    • (1983) J Nutr , vol.113 , pp. 2217-2222
    • De Schrijver, R.1    Privett, O.S.2
  • 34
    • 67650549976 scopus 로고    scopus 로고
    • An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Delta 8-desaturates 20:2n-6 and 20:3n-3
    • Park WJ, Kothapalli KSD, Lawrence P, Tyburczy C, Brenna JT. An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Delta 8-desaturates 20:2n-6 and 20:3n-3. J Lipid Res. 2009;50: 1195-202.
    • (2009) J Lipid Res , vol.50 , pp. 1195-1202
    • Park, W.J.1    Kothapalli, K.S.D.2    Lawrence, P.3    Tyburczy, C.4    Brenna, J.T.5
  • 35
    • 0016591196 scopus 로고
    • Absence of an 8-desaturase in rat-liver: reevaluation of optional pathways for metabolism of linoleic and linolenic acids
    • Sprecher H, Lee CJ. Absence of an 8-desaturase in rat-liver: reevaluation of optional pathways for metabolism of linoleic and linolenic acids. Biochim Biophys Acta. 1975;388:113-25.
    • (1975) Biochim Biophys Acta , vol.388 , pp. 113-125
    • Sprecher, H.1    Lee, C.J.2
  • 36
    • 0024550904 scopus 로고
    • Modification of fluidity and lipid protein relationships in pig intestinal brush-border membrane by dietary essential fatty-acid deficiency
    • Christon R, Even V, Daveloose D, Leger CL, Viret J. Modification of fluidity and lipid protein relationships in pig intestinal brush-border membrane by dietary essential fatty-acid deficiency. Biochim Biophys Acta. 1989;980:77-84.
    • (1989) Biochim Biophys Acta , vol.980 , pp. 77-84
    • Christon, R.1    Even, V.2    Daveloose, D.3    Leger, C.L.4    Viret, J.5
  • 37
    • 0021882362 scopus 로고
    • Delta-5-desaturase activity in liver and brain microsomes during development of the pig
    • Clandinin MT, Wong K, Hacker RR. Delta-5-desaturase activity in liver and brain microsomes during development of the pig. Biochem J. 1985;227:1021-3.
    • (1985) Biochem J , vol.227 , pp. 1021-1023
    • Clandinin, M.T.1    Wong, K.2    Hacker, R.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.