Variations in proton scanned beam dose delivery due to uncertainties in magnetic beam steering

Medical Physics

Volumn 36, Issue 8, 2009, Pages 3693-3702

  Peterson, Stephen ^a   Polf, Jerimy ^a   Ciangaru, George ^b   Frank, Steven J ^b   Bues, Martin ^a   Smith, Al ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Dose uncertainties; GEANT4; Magnetic steering; Proton beam scanning; Proton therapy

Indexed keywords

MAGNETIC FIELD EFFECTS; MAGNETS; NOZZLE DESIGN; PROTON BEAM THERAPY; PROTON BEAMS; SCANNING;

DOSE UNCERTAINTIES; GEANT4; MAGNETIC STEERING; PROTON BEAM SCANNING; PROTON THERAPY;

MAGNETIC NOZZLES;

ARTICLE; BEAM THERAPY; DOSIMETER; HISTOGRAM; MAGNET; MAGNETIC FIELD; PRIORITY JOURNAL; PROTON RADIATION; PROTON THERAPY; RADIATION DOSE; UNCERTAINTY;

EID: 68149166775     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.3175796     Document Type: Article

References (16)

1. T. Kanai, " Spot scanning system for proton radiotherapy.," Med. Phys. 0094-2405 7, 365369 (1980). 10.1118/1.594693 (Pubitemid 10078018)
2. E. Pedroni, " The 200-MeV proton therapy project at the Paul Scherrer Institute: Conceptual design and practical realization.," Med. Phys. 0094-2405 22, 3753 (1995). 10.1118/1.597522
3. A. Lomax, " Intensity modulation methods for proton radiotherapy.," Phys. Med. Biol. 0031-9155 44, 185205 (1999). 10.1088/0031-9155/44/1/014 (Pubitemid 29062235)
4. E. Pedroni, in Proton and Charged Particle Radiotherapy, edited by, T. F. De Laney, and, H. M. Kooy, (Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia, 2008), pp. 4049.
5. A. Samuelsson, C. Mercke, and K. A. Johansson, " Systematic set-up errors for IMRT in the head and neck region: Effect on dose distribution.," Radiother. Oncol. 0167-8140 66, 303311 (2003). 10.1016/S0167-8140(02)00389-4 (Pubitemid 36556049)
6. Y. Tsunashima, " Efficiency of respiratory-gated delivery of synchrotron-based pulsed proton irradiation.," Phys. Med. Biol. 0031-9155 53, 19471959 (2008). 10.1088/0031-9155/53/7/010 (Pubitemid 351570901)
7. J. Lambert, N. Suchowerska, D. R. McKenzie, and M. Jackson, " Intrafractional motion during proton beam scanning.," Phys. Med. Biol. 0031-9155 50, 48534862 (2005). 10.1088/0031-9155/50/20/008 (Pubitemid 41417008)
8. C. L. Hector, S. Webb, and P. M. Evans, " The dosimetric consequences of inter-fractional patient movement on conventional and intensity-modulated breast radiotherapy treatments.," Radiother. Oncol. 0167-8140 54, 5764 (2000). 10.1016/S0167-8140(99)00167-X (Pubitemid 30055326)
9. A. J. Lomax, " Intensity modulated proton therapy and its sensitivity to treatment uncertainties 2: The potential effects of inter-fraction and inter-field motions.," Phys. Med. Biol. 0031-9155 53, 10431056 (2008). 10.1088/0031-9155/53/4/015 (Pubitemid 351238122)
10. A. J. Lomax, " Intensity modulated proton therapy and its sensitivity to treatment uncertainties 1: The potential effects of calculational uncertainties.," Phys. Med. Biol. 0031-9155 53, 10271042 (2008). 10.1088/0031-9155/53/4/014 (Pubitemid 351238121)
11. S. Agostinelli, " GEANT4A simulation toolkit.," Nucl. Instrum. Methods Phys. Res. A 0168-9002 506, 250303 (2003). 10.1016/S0168-9002(03)01368-8
12. H. Paganetti, H. Jiang, S. Y. Lee, and H. M. Kooy, " Accurate Monte Carlo simulations for nozzle design, commissioning, and quality assurance for a proton radiation therapy facility.," Med. Phys. 0094-2405 31, 21072118 (2004). 10.1118/1.1762792 (Pubitemid 38924832)
13. J. C. Polf, M. C. Harvey, U. Titt, W. D. Newhauser, and A. R. Smith, " Initial beam size study for passive scatter proton therapy. I. Monte Carlo verification.," Med. Phys. 0094-2405 34, 42134218 (2007). 10.1118/1.2789497 (Pubitemid 350029642)
14. R. Doucet, M. Olivares, F. DeBlois, E. B. Podgorsak, I. Kawrakow, and J. Seuntjens, " Comparison of measured and Monte Carlo calculated dose distributions in inhomogeneous phantoms in clinical electron beams.," Phys. Med. Biol. 0031-9155 48, 23392354 (2003). 10.1088/0031-9155/48/15/307 (Pubitemid 37020982)
15. E. Poon and F. Verhaegen, " Accuracy of the photon and electron physics in GEANT4 for radiotherapy applications.," Med. Phys. 0094-2405 32, 16961711 (2005). 10.1118/1.1895796 (Pubitemid 40880563)
16. S. W. Peterson, " Experimental validation of a Monte Carlo proton therapy nozzle model incorporating magnetically steered protons.," Phys. Med. Biol. 0031-9155 54, 32173229 (2009). 10.1088/0031-9155/54/10/017