메뉴 건너뛰기




Volumn 23, Issue 6, 2010, Pages 1075-1086

Omega-3 and omega-6 polyunsaturated fatty acids: Metabolism in mammals and immune response;Ácidos graxos poli-insaturados n-3 e n-6: Metabolismo em mamíferos e resposta imune

Author keywords

Eicosanoids; Mice; Omega 3 fatty acids; Polyunsaturated fatty acids

Indexed keywords

ANIMALIA; MAMMALIA; MUS;

EID: 79955442444     PISSN: 14155273     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1415-52732010000600013     Document Type: Article
Times cited : (64)

References (63)
  • 1
    • 0034237584 scopus 로고    scopus 로고
    • Essential fatty acids and the brain: possible health implications
    • Youdim KA, Martin A, Joseph JA. Essential fatty acids and the brain: possible health implications. Int J Dev Neurosci. 2000; 18(4/5):383-99.
    • (2000) Int J Dev Neurosci , vol.18 , Issue.4-5 , pp. 383-399
    • Youdim, K.A.1    Martin, A.2    Joseph, J.A.3
  • 2
    • 34248344638 scopus 로고    scopus 로고
    • Immune modulation by parenteral lipid emulsions
    • Wanten GJ, Calder PC. Immune modulation by parenteral lipid emulsions. Am J Clin Nutr. 2007; 85(5):1171-84.
    • (2007) Am J Clin Nutr , vol.85 , Issue.5 , pp. 1171-1184
    • Wanten, G.J.1    Calder, P.C.2
  • 3
    • 33947115254 scopus 로고    scopus 로고
    • Ácidos graxos poliinsaturados ômega-3 e ômega-6: importância e ocorrência em alimentos
    • doi: 10.1590/S1415-52732006000600 011
    • Martins CA, Almeida, VV, Ruiz MR, Visentainer JEL, Matshushita M, Souza, NE, et al. Ácidos graxos poliinsaturados ômega-3 e ômega-6: importância e ocorrência em alimentos. Rev Nutr. 2006; 19(6): 761-70. doi: 10.1590/S1415-52732006000600 011.
    • (2006) Rev Nutr , vol.19 , Issue.6 , pp. 761-770
    • Martins, C.A.1    Almeida, V.V.2    Ruiz, M.R.3    Visentainer, J.E.L.4    Matshushita, M.5    Souza, N.E.6
  • 4
    • 79955379062 scopus 로고    scopus 로고
    • Ácidos graxos n-3: um link entre eicosanóides, inflamação e imunidade
    • Andrade PMM, Carmo MGT. Ácidos graxos n-3: um link entre eicosanóides, inflamação e imunidade. Rev Mn-Metabólica. 2006, 8(3):135-43.
    • (2006) Rev Mn-Metabólica , vol.8 , Issue.3 , pp. 135-143
    • Andrade, P.M.M.1    Carmo, M.G.T.2
  • 6
    • 79955460626 scopus 로고    scopus 로고
    • Biossegurança no manejo de animais em experimentação
    • Oda LM, Ávila S. Brasília: Fiocruz
    • Cardoso TAO. Biossegurança no manejo de animais em experimentação. In: Oda LM, Ávila S. Biossegurança em laboratórios de saúde pública. Brasília: Fiocruz; 1998.
    • (1998) Biossegurança em laboratórios de saúde pública
    • Cardoso, T.A.O.1
  • 8
    • 40749119757 scopus 로고    scopus 로고
    • Ethics and research
    • Shnaider TB. Ethics and research. Acta Cir Bras. 2008; 23(1):107-11.
    • (2008) Acta Cir Bras , vol.23 , Issue.1 , pp. 107-111
    • Shnaider, T.B.1
  • 9
    • 70350058003 scopus 로고    scopus 로고
    • Os Desafios das Comissões de Ética no Uso de Animais
    • Paixão RL. Os Desafios das Comissões de Ética no Uso de Animais. Ciênc Vet Tróp. 2008; 11(1):84-7.
    • (2008) Ciênc Vet Tróp , vol.11 , Issue.1 , pp. 84-87
    • Paixão, R.L.1
  • 10
    • 0030991110 scopus 로고    scopus 로고
    • N-3 fatty acids and serum lipoproteins: animal studies
    • Harris W.S. N-3 fatty acids and serum lipoproteins: animal studies. Am J Clin Nutr. 1997; 65 (suppl): 1611S -16S.
    • (1997) Am J Clin Nutr , vol.65 , Issue.SUPPL.
    • Harris, W.S.1
  • 11
    • 17544372067 scopus 로고    scopus 로고
    • The use of gene knockout mice in thermoregulation studies
    • Leon LR. The use of gene knockout mice in thermoregulation studies. J Therm Biol. 2005; 30(4):273-88.
    • (2005) J Therm Biol , vol.30 , Issue.4 , pp. 273-288
    • Leon, L.R.1
  • 12
    • 84903168014 scopus 로고    scopus 로고
    • Criação Criação e manejo de camundongos
    • Andrade A, Pinto S C, Oliveira RS. Rio de Janeiro: Fiocruz
    • Santos BF. Criação Criação e manejo de camundongos. In: Andrade A, Pinto S C, Oliveira RS. Animais de laboratório: criação e experimentação. Rio de Janeiro: Fiocruz; 2002.
    • (2002) Animais de laboratório: criação e experimentação
    • Santos, B.F.1
  • 13
    • 2942730234 scopus 로고    scopus 로고
    • A utilização de Símios do gênero Callithrix como modelo experimental
    • Andrade MCR. A utilização de Símios do gênero Callithrix como modelo experimental. Bol informat Col Bras Exper Anim. 1998. v.3.
    • (1998) Bol informat Col Bras Exper Anim , vol.3
    • Andrade, M.C.R.1
  • 15
    • 79955423328 scopus 로고    scopus 로고
    • Eutanásia: considerações éticas e indicações técnicas
    • Luna SPL, Teixeira MW. Eutanásia: considerações éticas e indicações técnicas. Rev CFMV. 2007; 13(41):60-9.
    • (2007) Rev CFMV , vol.13 , Issue.41 , pp. 60-69
    • Luna, S.P.L.1    Teixeira, M.W.2
  • 16
    • 0037321753 scopus 로고    scopus 로고
    • Biosynthesis of docosahexaenoic acid (DHA, 22:6-4,7,10,13,16,19): two distinct pathways
    • Qiu X. Biosynthesis of docosahexaenoic acid (DHA, 22:6-4,7,10,13,16,19): two distinct pathways. Prostaglandins Leukot Essent Fatty Acids. 2003; 68(2):181-6.
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.68 , Issue.2 , pp. 181-186
    • Qiu, X.1
  • 17
    • 33744736614 scopus 로고    scopus 로고
    • Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
    • Schaeffer H, Gohlke M, Müller IM, Heid LJ, Palmer I, Kompauer H, et al. Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum Mol Genet. 2006; 15(11):1745-56.
    • (2006) Hum Mol Genet , vol.15 , Issue.11 , pp. 1745-1756
    • Schaeffer, H.1    Gohlke, M.2    Müller, I.M.3    Heid, L.J.4    Palmer, I.5    Kompauer, H.6
  • 18
    • 0035147381 scopus 로고    scopus 로고
    • Review: The role of omega 3 fatty acids in intestinal inflamation
    • Teitelbaum JE, Walker WA. Review: The role of omega 3 fatty acids in intestinal inflamation J Nutr Biochem. 2001; 12(1):21-32.
    • (2001) J Nutr Biochem , vol.12 , Issue.1 , pp. 21-32
    • Teitelbaum, J.E.1    Walker, W.A.2
  • 19
    • 33646018341 scopus 로고    scopus 로고
    • fatty acid elongases in mammals: Their regulation and roles in metabolism
    • Jakobsson A, Westerberg R, Jacobsson A. fatty acid elongases in mammals: Their regulation and roles in metabolism. Prog Lipid Res. 2006; 45(3):237-49
    • (2006) Prog Lipid Res , vol.45 , Issue.3 , pp. 237-249
    • Jakobsson, A.1    Westerberg, R.2    Jacobsson, A.3
  • 20
    • 33748733341 scopus 로고
    • Importância fisiológica e patológica dos ácidos graxos
    • Tahin QS. Importância fisiológica e patológica dos ácidos graxos. Arq Biol Tecnol. 1985; 28(3):335-61.
    • (1985) Arq Biol Tecnol , vol.28 , Issue.3 , pp. 335-361
    • Tahin, Q.S.1
  • 22
    • 67849129098 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and cardiovascular diseases
    • Carl JL, Richard VM, Mandeep RM, Hector OV. Omega-3 polyunsaturated fatty acids and cardiovascular diseases. JACC. 2009; 54(7):585-94.
    • (2009) JACC , vol.54 , Issue.7 , pp. 585-594
    • Carl, J.L.1    Richard, V.M.2    Mandeep, R.M.3    Hector, O.V.4
  • 23
    • 62149099518 scopus 로고    scopus 로고
    • Fish oil and the management of hypertriglyceridemia
    • Mattar M, Obeid O. Fish oil and the management of hypertriglyceridemia. Nutr Health. 2009; 20(1): 41-9
    • (2009) Nutr Health , vol.20 , Issue.1 , pp. 41-49
    • Mattar, M.1    Obeid, O.2
  • 24
    • 72449165893 scopus 로고    scopus 로고
    • Anti-inflammatory effects of polyunsaturated fatty acids on the inflammatory response in asthma
    • Mickleborough TD. Anti-inflammatory effects of polyunsaturated fatty acids on the inflammatory response in asthma. Agro Food Ind Hi-Tech. 2009; 20(4):10-2.
    • (2009) Agro Food Ind Hi-Tech , vol.20 , Issue.4 , pp. 10-12
    • Mickleborough, T.D.1
  • 26
    • 34547131318 scopus 로고    scopus 로고
    • Novel metabolism of docosahexaenoic acid in neural cells
    • Kim HY. Novel metabolism of docosahexaenoic acid in neural cells. J Biol Chem. 2007; 282(26):18661-5
    • (2007) J Biol Chem , vol.282 , Issue.26 , pp. 18661-18665
    • Kim, H.Y.1
  • 27
    • 69449088787 scopus 로고    scopus 로고
    • Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammation
    • Chapkin RS, Kim W, Lupton JR, McMurray DN. Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammation. Prostag Leuk Essent Fatty Acids. 2009; 81(2-3):187-91.
    • (2009) Prostag Leuk Essent Fatty Acids , vol.81 , Issue.2-3 , pp. 187-191
    • Chapkin, R.S.1    Kim, W.2    Lupton, J.R.3    McMurray, D.N.4
  • 28
    • 36849066352 scopus 로고    scopus 로고
    • Piccioni E. n-3 polyunsaturated fatty acids and the prevention of colorectal cancer: Molecular mechanisms involved
    • Calviello G, Serini S, Piccioni E. n-3 polyunsaturated fatty acids and the prevention of colorectal cancer: Molecular mechanisms involved. Curr Med Chem. 2007; 14(29):81-9.
    • (2007) Curr Med Chem , vol.14 , Issue.29 , pp. 81-89
    • Calviello, G.1    Serini, S.2
  • 29
    • 79955379062 scopus 로고    scopus 로고
    • Ácidos graxos n-3: um link entre eicosanóides, inflamação e imunidade
    • Andrade PMM, Carmo MGT. Ácidos graxos n-3: um link entre eicosanóides, inflamação e imunidade. Rev Mn-Metabólica. 2006; 8(3):135-43.
    • (2006) Rev Mn-Metabólica , vol.8 , Issue.3 , pp. 135-143
    • Andrade, P.M.M.1    Carmo, M.G.T.2
  • 30
    • 33746814989 scopus 로고    scopus 로고
    • n-3 fatty acids and cognitive and visual acuity development: methodologic and conceptual considerations
    • Cheatham CL, Colombo J, Carlson SE. n-3 fatty acids and cognitive and visual acuity development: methodologic and conceptual considerations. Am J Clin Nutr. 2006; 83(6):1458S-66S.
    • (2006) Am J Clin Nutr , vol.83 , Issue.6
    • Cheatham, C.L.1    Colombo, J.2    Carlson, S.E.3
  • 31
    • 51649100533 scopus 로고    scopus 로고
    • Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents
    • 31.Wurtman RJ. Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents. Metab Clin Exp. 2008; 57(10):S6-S10.
    • (2008) Metab Clin Exp , vol.57 , Issue.10
    • Wurtman, R.J.1
  • 32
    • 58149308844 scopus 로고    scopus 로고
    • Altered lipid metabolism in brain injury and disorders
    • Adibhatla RM, Hatcher JF. Altered lipid metabolism in brain injury and disorders. Subcell Biochem. 2008; 49(1):241-68.
    • (2008) Subcell Biochem , vol.49 , Issue.1 , pp. 241-268
    • Adibhatla, R.M.1    Hatcher, J.F.2
  • 33
    • 33746830525 scopus 로고    scopus 로고
    • n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases
    • Calder P. n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr. 2006; 83 (suppl):1505S-19S.
    • (2006) Am J Clin Nutr , vol.83 , Issue.SUPPL.
    • Calder, P.1
  • 34
    • 33846274194 scopus 로고    scopus 로고
    • Balanço entre ácidos graxos ômega-3 e 6 na resposta inflamatória em pacientes com câncer e caquexia
    • doi: 10.1590/S1415-5273200600050000 9
    • Garófolo A, Petrilli AS. Balanço entre ácidos graxos ômega-3 e 6 na resposta inflamatória em pacientes com câncer e caquexia. Rev Nutr. 2006; 19(5): 611-21. doi: 10.1590/S1415-5273200600050000 9.
    • (2006) Rev Nutr , vol.19 , Issue.5 , pp. 611-621
    • Garófolo, A.1    Petrilli, A.S.2
  • 35
    • 37149056955 scopus 로고    scopus 로고
    • Dietary supplementation with fish oil modifies the ability of human monocytes to induce an inflammatory response
    • Luu NT, Madden J, Calder PC, Grimble R, Shearman CP, Chan Y, et al. Dietary supplementation with fish oil modifies the ability of human monocytes to induce an inflammatory response. J Nutr. 2007; 137(12):2769-74.
    • (2007) J Nutr , vol.137 , Issue.12 , pp. 2769-2774
    • Luu, N.T.1    Madden, J.2    Calder, P.C.3    Grimble, R.4    Shearman, C.P.5    Chan, Y.6
  • 36
    • 35548930759 scopus 로고    scopus 로고
    • Fatty acids and early human development
    • Innis SM. Fatty acids and early human development. Early Hum Dev. 2007; 83(12):761-66.
    • (2007) Early Hum Dev , vol.83 , Issue.12 , pp. 761-766
    • Innis, S.M.1
  • 37
    • 15444361997 scopus 로고    scopus 로고
    • Highly unsaturated fatty acid synthesis in vertebrates: new insights with the cloning and characterization of a delta6 desaturase of Atlantic salmon
    • Zheng X, Tocher DR, Dickson CA, Bell JG, Teale AJ. Highly unsaturated fatty acid synthesis in vertebrates: new insights with the cloning and characterization of a delta6 desaturase of Atlantic salmon. Lipids. 2005; 40(1):13-24
    • (2005) Lipids , vol.40 , Issue.1 , pp. 13-24
    • Zheng, X.1    Tocher, D.R.2    Dickson, C.A.3    Bell, J.G.4    Teale, A.J.5
  • 38
    • 21744446895 scopus 로고    scopus 로고
    • Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases
    • Wang Y, Botolin D, B. Christian B, Busik J, Xu J, Jump DB. Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases. J Lipid Res. 2005; 46(4):706-15
    • (2005) J Lipid Res , vol.46 , Issue.4 , pp. 706-715
    • Wang, Y.1    Botolin, D.B.2    Christian, B.3    Busik, J.4    Xu, J.5    Jump, D.B.6
  • 39
    • 25844437057 scopus 로고    scopus 로고
    • Dietary α-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels
    • Barcelò-Coblijin G, Collison LW, Jolly CA, Murphy EJ. Dietary α-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels. Lipids. 2005; 40(8):787-98.
    • (2005) Lipids , vol.40 , Issue.8 , pp. 787-798
    • Barcelò-Coblijin, G.1    Collison, L.W.2    Jolly, C.A.3    Murphy, E.J.4
  • 40
    • 62549150332 scopus 로고    scopus 로고
    • Quantitation of alpha-linolenic acid elongation to eicosapentaenoic and docosahexaenoic acid as affected by the ratio of n6/n3 fatty acids
    • Harnack K, Andersen G, Somoza V. Quantitation of alpha-linolenic acid elongation to eicosapentaenoic and docosahexaenoic acid as affected by the ratio of n6/n3 fatty acids. Nutr Metab. 2009; 6(8):1-11.
    • (2009) Nutr Metab , vol.6 , Issue.8 , pp. 1-11
    • Harnack, K.1    Andersen, G.2    Somoza, V.3
  • 41
    • 5644244809 scopus 로고    scopus 로고
    • Incorporation of n-3 fatty acid into plasma and liver lipids of rats: Importance of background dietary fat
    • MacDonald-Wicks LK, Garg ML. Incorporation of n-3 fatty acid into plasma and liver lipids of rats: Importance of background dietary fat. Lipids. 2004; 39(6):545-51.
    • (2004) Lipids , vol.39 , Issue.6 , pp. 545-551
    • MacDonald-Wicks, L.K.1    Garg, M.L.2
  • 42
    • 3242763991 scopus 로고    scopus 로고
    • Dose effect of α-linolenic acid on PUFA conversion, bioavailability and storage in the hamster
    • Morise A, Combe N, Boué C, legrand P, Catherine D, Delplanque B, et al. Dose effect of (-linolenic acid on PUFA conversion, bioavailability and storage in the hamster. Lipids. 2004; 39(4):325-34.
    • (2004) Lipids , vol.39 , Issue.4 , pp. 325-334
    • Morise, A.1    Combe, N.2    Boué, C.3    legrand, P.4    Catherine, D.5    Delplanque, B.6
  • 43
    • 0038018156 scopus 로고    scopus 로고
    • Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 and n-3 fatty acid ratio
    • Barcelò-Coblijin G, Kitajka K, Puskas LG, Hogyes E, Zvara A, Hackler L, et al. Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 and n-3 fatty acid ratio. Biochim Biophys Acta. 2003; 1632(1-2):72-9.
    • (2003) Biochim Biophys Acta , vol.1632 , Issue.1-2 , pp. 72-79
    • Barcelò-Coblijin, G.1    Kitajka, K.2    Puskas, L.G.3    Hogyes, E.4    Zvara, A.5    Hackler, L.6
  • 44
    • 0034063784 scopus 로고    scopus 로고
    • High dietary 18:3n-3 increases in the 18:3n-3 but not the 22:6n-3 content in the whole body, brain, skin, epididymal fat pads and muscles of suckling rat pups
    • Bowen RAR, Clandinin MT. High dietary 18:3n-3 increases in the 18:3n-3 but not the 22:6n-3 content in the whole body, brain, skin, epididymal fat pads and muscles of suckling rat pups. Lipids. 2000; 35(4):389-94.
    • (2000) Lipids , vol.35 , Issue.4 , pp. 389-394
    • Bowen, R.A.R.1    Clandinin, M.T.2
  • 45
    • 0037371226 scopus 로고    scopus 로고
    • Effects of beef- and fi sh-based diets on the kinetics of n-3 fatty acid metabolism in human subjects
    • Pawlosky RJ, Hibbeln JR, Lin, Y, Goodson S, Riggs P, Sebring N, et al. Effects of beef- and fi sh-based diets on the kinetics of n-3 fatty acid metabolism in human subjects. Am J Clin Nutr. 2003; 77(3): 565-72.
    • (2003) Am J Clin Nutr , vol.77 , Issue.3 , pp. 565-572
    • Pawlosky, R.J.1    Hibbeln, J.R.2    Lin, Y.3    Goodson, S.4    Riggs, P.5    Sebring, N.6
  • 46
    • 34248342195 scopus 로고    scopus 로고
    • Hyperactivity in the rat is associated with spontaneous low level of n-3 polyunsaturated fatty acids in the frontal córtex
    • Vancassel S, Blondeau C, Lallemand S, Cador M, Linard A, Lavialle M, et al. Hyperactivity in the rat is associated with spontaneous low level of n-3 polyunsaturated fatty acids in the frontal córtex. Behav Brain Res. 2007; 180(2):119-26.
    • (2007) Behav Brain Res , vol.180 , Issue.2 , pp. 119-126
    • Vancassel, S.1    Blondeau, C.2    Lallemand, S.3    Cador, M.4    Linard, A.5    Lavialle, M.6
  • 47
    • 0034235877 scopus 로고    scopus 로고
    • Marine oils: the health benefits of n-3 fatty acids
    • Uauy R, Valenzuela A. Marine oils: the health benefits of n-3 fatty acids. Nutrition. 2000; 16(7-8): 680-4.
    • (2000) Nutrition , vol.16 , Issue.7-8 , pp. 680-684
    • Uauy, R.1    Valenzuela, A.2
  • 48
    • 38349147105 scopus 로고    scopus 로고
    • The science behind dietary omega-3 fatty acids
    • Surette ME. The science behind dietary omega-3 fatty acids. Can Med Assoc J. 2008; 178:177-80.
    • (2008) Can Med Assoc J , vol.178 , pp. 177-180
    • Surette, M.E.1
  • 49
    • 79955378530 scopus 로고    scopus 로고
    • Institute of Medicine. Dietary Reference Intakes (DRIs) for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. Part 1. Washington (DC): National Academy Press
    • Institute of Medicine. Dietary Reference Intakes (DRIs) for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. Part 1. Washington (DC): National Academy Press; 2002.
    • (2002)
  • 50
    • 0036899459 scopus 로고    scopus 로고
    • The striking diet of the island of Crete: lipid nutrition from the palaeolithic to the affluent modern society
    • Fürst P. The striking diet of the island of Crete: lipid nutrition from the palaeolithic to the affluent modern society. Clin Nutr. 2002; 21(S2):9-14.
    • (2002) Clin Nutr , vol.21 , Issue.S2 , pp. 9-14
    • Fürst, P.1
  • 51
    • 0037413190 scopus 로고    scopus 로고
    • What is the role of α-linolenic acid for mammals?
    • Sinclair AJ, Attar-Bashi NM, Li D. What is the role of (-linolenic acid for mammals? Lipids. 2002; 37(12):1113-23.
    • (2002) Lipids , vol.37 , Issue.12 , pp. 1113-1123
    • Sinclair, A.J.1    Attar-Bashi, N.M.2    Li, D.3
  • 52
    • 33847392879 scopus 로고    scopus 로고
    • Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo
    • Jungestrom MB, Thompson LU, Dabrosin C. Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo. Clin Cancer Res. 2007; 13(3): 1061-7.
    • (2007) Clin Cancer Res , vol.13 , Issue.3 , pp. 1061-1067
    • Jungestrom, M.B.1    Thompson, L.U.2    Dabrosin, C.3
  • 53
    • 33645009635 scopus 로고    scopus 로고
    • Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice
    • Chen J, Wang L, Thompson LU. Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice. Cancer Lett. 2006; 234:168-75.
    • (2006) Cancer Lett , vol.234 , pp. 168-175
    • Chen, J.1    Wang, L.2    Thompson, L.U.3
  • 54
    • 13844255678 scopus 로고    scopus 로고
    • La expresión de IL-10 interviene em la regulación de la respuesta inflamatória por los ácidos grasos omega 3
    • Sierra S, Lara-Villoslada M, Olivares M, Jiménez J, Boza J, Xaus J. La expresión de IL-10 interviene em la regulación de la respuesta inflamatória por los ácidos grasos omega 3. Nutr Hosp. 2004; 19(6): 376-82.
    • (2004) Nutr Hosp , vol.19 , Issue.6 , pp. 376-382
    • Sierra, S.1    Lara-Villoslada, M.2    Olivares, M.3    Jiménez, J.4    Boza, J.5    Xaus, J.6
  • 55
    • 36649015221 scopus 로고    scopus 로고
    • Immunomodulation by omega-3 fatty acids
    • Calder P. Immunomodulation by omega-3 fatty acids. Prostaglandins, Leukot Essent Fatty Acids. 2007; 77(5-6):327-35.
    • (2007) Prostaglandins, Leukot Essent Fatty Acids , vol.77 , Issue.5-6 , pp. 327-335
    • Calder, P.1
  • 56
    • 0035925045 scopus 로고    scopus 로고
    • Imbalance of IL-2, IFN-gamma and IL-10 secretion in the imunosuppression associated with human paracoccidioidomycosis
    • Bernard G, Romano CC, Cacere CR, Juvenali M, Mendes-Giannini MJS, Duarte AJS. Imbalance of IL-2, IFN-gamma and IL-10 secretion in the imunosuppression associated with human paracoccidioidomycosis. Cytokine. 2001; 13(4): 248-52.
    • (2001) Cytokine , vol.13 , Issue.4 , pp. 248-252
    • Bernard, G.1    Romano, C.C.2    Cacere, C.R.3    Juvenali, M.4    Mendes-Giannini, M.J.S.5    Duarte, A.J.S.6
  • 57
    • 0024348309 scopus 로고
    • Essential fatty acids and the immune response
    • Hwang, D. Essential fatty acids and the immune response. FASEB J. 1989; 3:2052-61.
    • (1989) FASEB J , vol.3 , pp. 2052-2061
    • Hwang, D.1
  • 58
    • 0037452612 scopus 로고    scopus 로고
    • Differential effects of prostaglandin derived from w-6 and w-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion
    • Bagga D, Wang L, Eisner-Farias R, Glaspy JA, Reddy ST. Differential effects of prostaglandin derived from w-6 and w-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc Natl Acad Sci. 2003; 100(4):175-6.
    • (2003) Proc Natl Acad Sci , vol.100 , Issue.4 , pp. 175-176
    • Bagga, D.1    Wang, L.2    Eisner-Farias, R.3    Glaspy, J.A.4    Reddy, S.T.5
  • 59
    • 49749141035 scopus 로고    scopus 로고
    • Anti-inflammatory properties of omega-3 fatty acids in critical illness: novel mechanisms and an integrative perspective
    • Singer P, Shapiro H, Theilla M, Anbar R, Singer J, Cohen J. Anti-inflammatory properties of omega-3 fatty acids in critical illness: novel mechanisms and an integrative perspective. Intensive Care Med. 2008; 34(9):1580-92.
    • (2008) Intensive Care Med , vol.34 , Issue.9 , pp. 1580-1592
    • Singer, P.1    Shapiro, H.2    Theilla, M.3    Anbar, R.4    Singer, J.5    Cohen, J.6
  • 61
    • 34247638400 scopus 로고    scopus 로고
    • Differential immunomodulation with long-chain n-3 PUFA in health and chronic disease
    • Sijben JWC, Calder PC. Differential immunomodulation with long-chain n-3 PUFA in health and chronic disease. Proceed Nutr Soc. 2007; 66: 237-59.
    • (2007) Proceed Nutr Soc , vol.66 , pp. 237-259
    • Sijben, J.W.C.1    Calder, P.C.2
  • 62
    • 0034937107 scopus 로고    scopus 로고
    • Modulation of human Immune and Inflamatory responses by dietary fatty acids
    • Kelley DS. Modulation of human Immune and Inflamatory responses by dietary fatty acids. Nutrition. 2001; 17(7-8):669-73.
    • (2001) Nutrition , vol.17 , Issue.7-8 , pp. 669-673
    • Kelley, D.S.1
  • 63
    • 70349567915 scopus 로고    scopus 로고
    • Formação de toxinas durante o processamento de alimentos e as possíveis conseqüências para o organismo humano
    • doi: 10.1590/S1415-52732009000200010
    • Marques AC, Valente TB, Rosa CS. Formação de toxinas durante o processamento de alimentos e as possíveis conseqüências para o organismo humano. Rev Nutr. 2009, 22(2):283-93. doi: 10.1590/S1415-52732009000200010.
    • (2009) Rev Nutr , vol.22 , Issue.2 , pp. 283-293
    • Marques, A.C.1    Valente, T.B.2    Rosa, C.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.