Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: Role in tumour progression

British Journal of Dermatology

Volumn 164, Issue 5, 2011, Pages 1061-1070

  Ruffini, F ^a   Failla, C M ^a   Orecchia, A ^a   Bani, M R ^b   Dorio, A S ^c   Fortes, C ^a   Zambruno, G ^a   Graziani, G ^c   Giavazzi, R ^b   D'Atri, S ^a   Lacal, P M ^a  

^a LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PLACENTAL GROWTH FACTOR; SOLUBLE VASCULOTROPIN RECEPTOR 1; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MELANOCYTE; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SKIN METASTASIS; SKIN TUMOR; TUMOR CELL LINE; TUMOR GROWTH;

CELL LINE, TUMOR; DISEASE PROGRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MELANOMA; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; SKIN NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 79955423690     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2010.10200.x     Document Type: Article

References (28)

1. Graeven U, Fiedler W, Karpinski S,. Melanoma-associated expression of vascular endothelial growth factor and its receptors Flt-1 and KDR. J Cancer Res Clin Oncol 1999; 125: 621-9. (Pubitemid 29502343)
2. Lacal P, Failla CM, Pagani E, et al. Human melanoma cells secrete and respond to placenta growth factor and vascular endothelial growth factor. J Invest Dermatol 2000; 115: 1000-7. (Pubitemid 32037443)
3. Mahabeleshwar GH, Byzova TV,. Angiogenesis in melanoma. Semin Oncol 2007; 34: 555-65. (Pubitemid 350236307)
4. Einspahr JG, Thomas TL, Saboda K, et al. Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression. Cancer 2007; 110: 2519-27. (Pubitemid 350174939)
5. Marcoval J, Moreno A, Graells J, et al. Angiogenesis and malignant melanoma. Angiogenesis is related to the development of vertical (tumorigenic) growth phase. J Cutan Pathol 1997; 24: 212-18. (Pubitemid 27187016)
6. Graells J, Vinyals A, Figueras A, et al. Overproduction of VEGF concomitantly expressed with its receptors promotes growth and survival of melanoma cells through MAPK and PI3K signaling. J Invest Dermatol 2004; 123: 1151-61. (Pubitemid 39586840)
7. Lacal PM, Ruffini F, Pagani E, D'Atri S,. An autocrine loop directed by the vascular endothelial growth factor promotes invasiveness of human melanoma cells. Int J Oncol 2005; 27: 1625-32.
8. Marcellin M, De Luca N, Riccioni T, et al. Increased melanoma growth and metastasis spreading in mice overexpressing placenta growth factor. Am J Pathol 2006; 169: 643-54. (Pubitemid 44156320)
9. Lohela M, Bry M, Tammela T, et al. VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. Curr Opin Cell Biol 2009; 21: 154-65.
10. Kendall RL, Thomas KA,. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA 1993; 90: 10705-9. (Pubitemid 23347111)
11. Kendall RL, Wang G, Thomas KA,. Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 1996; 226: 324-8. (Pubitemid 26331903)
12. Kearney J, Kappas N, Ellerstrom C, et al. The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis. Blood 2004; 103: 4527-35. (Pubitemid 38745980)
13. Orecchia A, Lacal PM, Schietroma C, et al. Vascular endothelial growth factor receptor-1 is deposited in the extracellular matrix by endothelial cells and is a ligand for the α5β1 integrin. J Cell Sci 2003; 116: 3479-89. (Pubitemid 37063392)
14. Kimura M, Kato Y, Sano D, et al. Soluble form of ephrinB2 inhibits xenograft growth of squamous cell carcinoma of the head and neck. Int J Oncol 2009; 34: 321-7.
15. Tentori L, Vergati M, Muzi A, et al. Generation of an immortalized human endothelial cell line as a model of neovascular proliferating endothelial cells to assess chemosensitivity to anticancer drugs. Int J Oncol 2005; 27: 525-35.
16. Lichtenberger BM, Tan PK, Niederleithner H, et al. Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development. Cell 2010; 140: 268-79.
17. Wilgus TA, Matthies AM, Radek KA, et al. Novel function for vascular endothelial growth factor receptor-1 on epidermal keratinocytes. Am J Pathol 2005; 167: 1257-66. (Pubitemid 41541412)
18. Streit M, Detmar M,. Angiogenesis, lymphangiogenesis, and melanoma metastasis. Oncogene 2003; 22: 3172-9. (Pubitemid 36713769)
19. Lamszus K, Ulbricht U, Matschke J, et al. Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A. Clin Cancer Res 2003; 9: 1399-405. (Pubitemid 36418393)
20. Pritchard-Jones RO, Dunn DBA, Qiu Y, et al. Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma. Br J Cancer 2007; 97: 223-30. (Pubitemid 47057469)
21. Liu B, Ma J, Wang X, et al. Lymphangiogenesis and its relationship with lymphatic metastasis and prognosis in malignant melanoma. Anat Rec 2008; 291: 1227-35.
22. Schietroma C, Cianfarani F, Lacal P, et al. Vascular endothelial growth factor-C expression correlates with lymph node localization of human melanoma metastases. Cancer 2003; 98: 789-97. (Pubitemid 36959276)
23. Achen MG, Stacker SA,. Molecular control of lymphatic metastasis. Ann NY Acad Sci 2008; 1131: 225-34. (Pubitemid 351758517)
24. Soro S, Orecchia A, Morbidelli L, et al. A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through α5β1 integrin. Blood 2008; 111: 3479-88.
25. Schwartz JD, Rowinsky EK, Youssoufian H, et al. Vascular endothelial growth factor receptor-1 in human cancer: concise review and rationale for development of IMC-18F1 (human antibody targeting vascular endothelial growth factor receptor-1). Cancer 2010; 116: 1027-32.
26. Mehnert JM, McCarthy MM, Aziz SA, et al. VEGF, VEGFR1, and VEGFR2 expression in melanoma. J Clin Oncol 2007; 25: 8520.
27. Graeven U, Rodeck U, Karpinski S, et al. Expression patterns of placenta growth factor in human melanocytic cell lines. J Invest Dermatol 2000; 115: 118-23. (Pubitemid 30470202)
28. Wu Y, Zhu Z,. Vascular endothelial growth factor receptor 1, a therapeutic target in cancer, inflammation and other disorders. Curr Med Chem 2009; 16: 2890-8.