Effect of estrogen therapy, soy isoflavones, and the combination therapy on the submandibular gland of ovariectomized rats

Pathology Research and Practice

Volumn 207, Issue 5, 2011, Pages 300-305

  Carvalho, Vinicius Diniz Chaves ^a   Silveira, Vanessa Ávila Sarmento ^b   do Prado, Renata Falchete ^b   Carvalho, Yasmin Rodarte ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b Laboratory of Anatomy Faculty of Pindamonhangaba ^*  (Brazil)

Author keywords

Estrogen therapy; Isoflavones; Ovariectomy; Salivary glands

Indexed keywords

ESTRADIOL VALERATE; ISOFLAVONE; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ESTROGEN DEFICIENCY; FEMALE; MONOTHERAPY; NONHUMAN; OVARIECTOMY; RAT; SALIVARY GLAND DUCT; SALIVARY GLAND FUNCTION; SUBMANDIBULAR GLAND;

EID: 79955412529     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2011.01.002     Document Type: Article

References (44)

1. Alves D.L., Silva R.C. Fitohormônios: abordagem natural da terapia hormonal 2002, Atheneu, São Paulo, p. 106.
2. Amenábar J.M., Pawlowski J., Hilgert J.B., Hugo F.N., Bandeira D., Lhüller F., et al. Anxiety and salivary cortisol levels in patients with burning mouth syndrome: case-control study. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2008, 105:460-465.
3. Arakaki R., Nagaoka A., Ishimaru N., Yamada A., Yoshida S., Hayashi Y. Role of plasmacytoid dendritic cells for aberrant class II expression in exocrine glands from estrogen-deficient mice of healthy background. Am. J. Pathol. 2009, 174:1715-1724.
4. Bellavia S.L., Sanz E.G., Vermouth N.T., Blanco A. Effect of sexual steroids upon ontogeny of alpha-amylase of rat parotid gland. Mol. Cell. Biochem. 1982, 44:65-69.
5. Ben-Arieh H., Gottlieb I., Ish-Shalom S., David A., Szargel H., Laufer D. Oral complaints related to menopause. Maturitas 1996, 24:185-189.
6. Bjorling D.E., Beckman M., Clayton M.Z., Wang Y. Modulation of nerve growth factor in peripheral organs by estrogen and progesterone. Neuroscience 2002, 110:155-167.
7. Blake E., Medrano T., Katz J., Shiverick K.T. Genistein's effect on expression of HSG cell cycle regulatory proteins. IADR/AADR/CADR 82nd (Abstract) 2004, 10-13.
8. Breitman P.L., Fonseca D., Cheung A.M., Warda W.E. Isoflavones with supplemental calcium provide greater protection against the loss of bone mass and strength after ovariectomy compared to isoflavones alone. Bone 2003, 33:597-605.
9. Cairns B.E. The influence of gender and sex steroids on craniofacial nociception. Headache 2007, 47:319-324.
10. Campbel P.S., Ben-Arieh H., Swanson K.A. Differential distribution of an estrogen receptor in the submandibular and parotid salivary glands of female rats. Endocr. Res. 1990, 16:333-345.
11. Cheong J.M.K., Martin B.R., Jackson G.S., Elmore D., McCabe G.P., Nolan J.R., et al. Soy isoflavones do not affect bone resorption in postmenopausal women: a dose-response study using a novel approach with 41ca. J. Clin. Endocrinol. Metabol. 2007, 92:577-582.
12. C.E. Colombo, Efeitos do estrógeno e da progesterona na regeneração da glândula parótida após atrofia por ligadura do ducto excretor: estudo histológico e imunoisquímico em ratas pós-ovariectomia. Thesis, Faculdade de Odontologia de São José dos Campos, Universidade Estadual Paulista, São José dos Campos, 2004.
13. de Rijk E.P., Ravesloot W.T., Hafmans T.G., van Esch E. Multifocal ductal cell hyperplasia in the submandibular salivary glands of Wistar rats chronically treated with a novel steroidal compound. Toxicol. Pathol. 2003, 31:1-9.
14. Deyhim F., Stoecker B.J., Brusewitz G.H., Arjmandi B.H. The effects of estrogen depletion and isoflavones on bone metabolism in rats. Nutr. Res. 2003, 23:123-130.
15. Dimery I.W., Jones L.A., Verjan R.P., Raymond A.K., Goepfert H., Hong W.K. Estrogen receptors in normal salivary gland and salivary gland carcinoma. Arch. Otolaryngol. Head Neck Surg. 1987, 113:1082-1085.
16. Eliasson L., Carlén A., Laine M., Birkhed D. Minor gland and whole saliva in postmenopausal women using a low potency oestrogen (oestriol). Arch. Oral Biol. 2003, 48:511-517.
17. Flynn E.A., Yelland K.T., Shklar G. Effect of estradiol on ultrastructure of granular ducts in submandibular glands of female rats. Anat. Rec. 1983, 206:23-30.
18. Forabosco A., Criscuolo M., Coukos G., Uccelli E., Weinstein R., Spinato S., et al. Efficacy of hormone replacement therapy in postmenopausal women with oral discomfort. Oral Surg. Oral Med. Oral Pathol. 1992, 73:570-574.
19. Giuca M.R., Carli E., Pasini M., Bonfigli D., Cappè M.R. Evaluation of efficacy of estrogen and phytotherapy in oral cavity alterations of women in menopause. Minerva Ginecol. 2009, 61:13-22.
20. Kalu D.N. The ovariectomized rat model of postmenopausal bone loss. Bone Miner. 1991, 15:175-191.
21. Kusunoki T., Shiraishi H., Murata K. The role of estrogen and Cu Zn-SOD on histological changes after menopause in female rat parotid. Auris Nasus Larynx 2006, 33:47-51.
22. Laine M., Leimola-Virtanen R. Effect of hormone replacement therapy on salivary flow rate buffer effect and pH in perimenopausal and postmenopausal women. Arch. Oral Biol. 1996, 41:91-96.
23. Laine M., Tenovuo J. Effect on peroxidase activity and specific binding of the hormone 17 beta-oestradiol and rat salivary glands. Arch. Oral Biol. 1983, 28:847-852.
24. Lane N.E., Thompson J.M., Haupt D., Kimmel D.B., Modin G., Kinney J.H. Acute changes in trabecular bone connectivity and osteoclast activity in the ovariectomized rat in vivo. J. Bone Miner. Res. 1998, 13:229-236.
25. Leimola-Virtanen R., Salo T., Toikkanen S., Pulkinen J., Syrjanen S. Expression of estrogen receptor (ER) in oral mucosa and salivary glands. Maturitas 2000, 36:131-137.
26. Maltsman-Tseikhin A., Moricca P., Niv D. Burning mouth syndrome: will better understanding yield better management?. Pain Pract. 2007, 7:151-162.
27. Most W., van der Wee-Pals L., Ederveen A., Papapoulos S., Lowik C. Ovariectomy and orchidectomy induce a transient increase in the osteoclastogenic potential of bone marrow cells in the mouse. Bone 1997, 20:27-30.
28. Naftolin F., Stanbury M.G. Phytoestrogens: are they really estrogen mimics?. Fertil. Steril. 2002, 77:15-17.
29. Ozono S., Onozuka M., Sato K., Ito Y. Immunohistochemical localization of estradiol, progesterone, and progesterone receptor in human salivary gland and salivary adenoid cystic carcinomas. Cell Struct. Funct. 1992, 17:169-175.
30. Purushotham K.R., Wang P.L., Dolce C., Zelles T., Blazsek J., Humphreys-Beher M.G. Effects of surgical ovariectomy on rat salivary gland function. Arch. Oral Biol. 1993, 38:779-784.
31. Rins de David M.L., Finkelberg de Sterin A., Goldraij A. Influence of gonadic hormones on the rat submaxillary gland. Arch. Int. Physiol. Biochim. Biophys. 1991, 99:107-109.
32. Seko K., Kagami H., Senga K., Ozeki K., Mizutani H., Ueda M. Effects of ovariectomy and estrogen replacement on rat oral mucosa. Maturitas 2005, 50:44-51.
33. Smith J., Lindsay M., Rahimian R., Anderson L. The influence of estrogen and progesterone on parasympathetic vasodilatation in the rat submandibular gland. Auton. Neurosci. 2009, 146:87-94.
34. Streckfus G.F., Baur U., Brown L.J., Baca C., Metter J., Nick T. Effects of estrogen status and aging on salivary flow rates in healthy Caucasian women. Gerontology 1998, 44:32-39.
35. Tanaka M., Watanabe M., Kumai T., Nakura H., Kobayashi S. Effects of submaxillariectomy on ovarian androgen and estrogen production in adult female rats. Biochem. Biophys. Res. Commun. 1995, 213:550-554.
36. Tivesten A., Movérare-Skrtic S., Chagin A., Venken K., Salmon P., Vanderschueren D., Sävendahl L., Holmäng A., Ohlsson C. Additive protective effects of estrogen and androgen treatment on trabecular bone in ovariectomized rats. J. Bone Miner. Res. 2004, 19:1833-1839.
37. Välimaa H., Savolainen S., Soukka T., Silvoniemi P., Mäkelä S., Kujari H., et al. Estrogen receptor-β is the predominant estrogen receptor subtype in human oral epithelium and salivary glands. J. Endocrinol. 2004, 180:55-62.
38. Vittek J., Hernandez M.R., Wenk E.J., Rappaport S.C., Southren A.L. Specific estrogen receptors in human gingiva. J. Clin. Endocrinol. Metab. 1982, 54:608-612.
39. Waddell B.J., O'Leary P.C. Distribution and metabolism of topically applied progesterone in a rat model. J. Steroid Biochem. Mol. Biol. 2002, 80:449-455.
40. Waldrop R.W., Hailes J., Burger H., Reade P.C. Oral discomfort at menopause. Oral Surg. Oral Med. Oral Pathol. 1989, 67:535-540.
41. Weibel E.R., Kistler G.S., Scherle W.F. Practical stereological methods for morphometric cytology. J. Cell Biol. 1966, 30:23-38.
42. Wood C.E., Register T.C., Franke A.A., Anthony M.S., Cline J.M. Dietary soy isoflavones inhibit estrogen effects in the postmenopausal breast. Cancer Res. 2006, 66:1241-1249.
43. Wronski T.J., Cintrón M., Dann L.M. Temporal relationship between bone loss and increased bone turnover in ovariectomized rats. Calcif Tissue Int. 1988, 43:179-183.
44. Zaffe D., Paganelli C., Cocchi D. Induction and pharmacological treatment of oral osteopenia in rats. Minerva Stomatol. 1999, 48:45-62.