Soy isoflavones do not affect bone resorption in postmenopausal women: A dose-response study using a novel approach with41Ca

Journal of Clinical Endocrinology and Metabolism

Volumn 92, Issue 2, 2007, Pages 577-582

  Cheong, J M K ^a   Martin, B R ^a   Jackson, G S ^a   Elmore, D ^a   McCabe, G P ^b   Nolan, J R ^b   Barnes, S ^c   Peacock, M ^d   Weaver, C M ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL TELOPEPTIDE; BIOLOGICAL MARKER; CALCIUM; ISOFLAVONE; OSTEOCALCIN; SOYBEAN PROTEIN;

ADULT; AGED; ARTICLE; BONE TURNOVER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; FEMALE; HUMAN; MASS SPECTROMETRY; NORMAL HUMAN; OSTEOLYSIS; POSTMENOPAUSE; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE;

EID: 33846978077     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2006-0369     Document Type: Article

References (34)

1. Raisz LG, Wiita B, Artis A, Bowen A, Schwartz S, Trahiotis M, Shoukri K, Smith J 1996 Comparison of the effects of estrogen alone and estrogen plus androgen on biochemical markers of bone formation and resorption in postmenopausal women. J Clin Endocrinol Metab 81:37-43
2. Writing Group for the Women's Health Initiative Investigators 2002 Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 288:321-333
3. Potter SM, Baum JA, Teng H, Stillman RJ, Shay NF, Erdman JW 1998 Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. Am J Clin Nutr 68(suppl):1375S-1379S
4. Alekel DL, Germain AS, Peterson CT, Hanson KB, Stewart JW, Toda T 2000 Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. Am J Clin Nutr 72:844-852
5. Anderson JJB, Chen X, Boass A, Symons M, Kohlmeier M, Renner JB, Garner SC 2002 Soy isoflavones: no effects on bone mineral content and bone mineral density in healthy, menstruating young adult women after one year. J Am Coll Nutr 21:388-393
6. Gallagher JC, Satpathy R, Rafferty K, Haynatzka V 2004 The effect of soy protein isolate on bone metabolism. Menopause 11:290-298
7. Kreijkamp-Kaspers S, Kok L, Grobbee DE, de Haan EHF, Aleman A, Lampe JW, van der Schouw YT 2004 Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial. JAMA 292:65-74
8. Alexandersen P, Toussaint A, Christiansen C, Devogelaer JP, Roux C, Fechtenbaum J, Gennari C, Reginster JY 2001 Ipriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial. JAMA 285:1482-1488
9. Zhang X, Shu X, Li H, Yang G, Li Q, Gao Y, Zheng W 2005 Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women. Arch Intern Med 165:1890-1895
10. Srivastava AK, Vliet EL, Lewiecki EM, Maricic M, Abdelmalek A, Gluck O, Baylink DJ 2005 Clinical use of serum and urine bone markers in the management of osteoporosis. Curr Med Res Opin 21:1015-1026
11. Jackson GS, Weaver CM, Elmore D 2001 Use of accelerator mass spectrometry for studies in nutrition. Nutr Res Rev 14:317-334
12. 41Ca: past, present and future. Nucl Instrum Methods Phys Res B 52:572-582
13. 41Ca and accelerator mass spectrometry to monitor calcium metabolism in end stage renal disease patients. Clin Chem 51:2095-2102
14. 41Ca. Nucl Instrum Methods Phys Res B 172:930-933
15. Nieves JW, Koniar L, Cosman F, and Lindsay R 1998 Calcium potentiates the effect of estrogen and calcitonin on bone mass: review and analysis. Am J Clin Nutr 67:18-24
16. Heaney RP, Recker RR 1988 Estimating true fractional calcium absorption. Ann Int Med 108:905-906
17. Barnes S, Coward L, Kirk M, Sfakianos J 1998 HPLC-mass spectrometry analysis of isoflavones. Exp Biol Med 217:254-262
18. National Center for Health Statistics 2005 Third National Health and Nutrition Examination Survey (NHANES III). Anthropometric Reference Data, 1988-1994 National Center for Health Statistics. Available at: http://www. cdc.gov/nchs/about/major/nhanes/Anthropometric%20Measures.htm Tables 6, 9, 15. Accessed September 28
19. Looker AC, Wahner HW, Dunn WL, Calvo MS, Marris TB, Heyse SP, Johnston Jr CC, Lindsay R 1998 Updated data on proximal femur bone mineral levels of US adults. Osteoporos Int 8:468-489
20. Kleerkoper M, Nelson DA, Peterson EL, Flynn MJ, Pawluska AS, Jacobsen G, Wilson P 1994 Reference data for bone mass, calciotropic hormones, and biochemical markers of bone remodeling in older (55-78) postmenopausal white and black women. J Bone Miner Res 9:1267-1276
21. Favus MJ 2003 Laboratory values related to calcium metabolism/metabolic bone disease. In: Primer on the metabolic bone diseases and disorders of mineral metabolism. 5th ed. Philadelphia: Lippincott Williams, Wilkins; 546-550
22. Eastell R, Barton I, Hannon RA, Chines A, Garnero P, Delmas PD 2003 Relationship of early changes in bone resorption to the reduction in fracture risk with Risedronate. J Bone Miner Res 18:1051-1056
23. Wong WW 2000 Effects of soy isoflavones on blood lipids, blood pressure and biochemical markers of bone metabolism in postmenopausal women. J Nutr 130:686S (Abstract)
24. Cai DJ, Zhao Y, Glasier J, Cullen D, Barnes S, Turner CH, Wastney M, Weaver CM 2005 Comparative effect of soy protein, soy isoflavones, and 17β-estradiol on bone metabolism in adult ovariectomized rats. J Bone Miner Res 20:828-839
25. Spence LA, Lipscomb ER, Cadogan J, Martin B, Wastney ME, Peacock M, Weaver CM 2005 The effect of soy protein and soy isoflavones on calcium metabolism in postmenopausal women: a randomized crossover study. Am J Clin Nutr 81:916-922
26. Wangen KE, Duncan AM, Merz-Demlow BE, Xu X, Marcus R, Phipps WR, Kurzer MS 2000 Effects of soy isoflavones on markers of bone turnover in premenopausal and postmenopausal women. J Clin Endocrinol Metab 85:3043-3048
27. Lydeking-Olsen E, Beck-Jensen J-E, Setchell KDR, Holm-Jensen T 2004 Soymilk or progesterone for prevention of bone loss: a 2 year randomized, placebo-controlled trial. Eur J Nutr 43:246-257
28. Devine A, Prince RL, Kerr DA, Dick IM, Criddle RA, Kent GN, Price RI, Webb PG 1993 Correlates of intestinal calcium absorption in women 10 years past the menopause. Calcif Tissue Int 52:358-360
29. Arjmandi BH, Hollis BW, Kalu DN 1994 In vivo effect of 17 β-estradiol on intestinal calcium absorption in rats. Bone Miner 26:181-189
30. Chailurkita L, Ongphiphadhanakul B, Piaseu N, Saetung S, Rajatanavin R 2001 Biochemical markers of bone turnover and response of bone mineral density to intervention in early postmenopausal women: an experience in a clinical laboratory. Clin Chem 47:1083-1088
31. Eastel R, Colwell A, Hampton L, Reev J 1997 Biochemical markers of bone resorption compared with estimates of bone resorption from radiotracer kinetic studies in osteoporosis. J Bone Miner Res 12:59-65
32. Villareal DT, Binder EF, Williams DB, Schechitman KB, Yarasheski KE, Kohrt WM 2001 Bone mineral density response to estrogen replacement in frail elderly women. JAMA 286:815-820
33. Leung JYY, Ho AYY, IP TP, Lee G, Kung AWC 2005 The efficacy and tolerability of risedronate on bone mineral density and bone turnover markers in osteoporotic Chinese women: a randomized placebo-controlled study. Bone 36:358-364
34. Harris ST, Ericksen EF, Davidson M, Ettinger MP, Moffett Jr AH, Baylink DJ, Crusan CE, Chines AA 2001 Effect of combined residronate and hormone replacement therapies on bone mineral density in postmenopausal women. J Clin Endocrinol Metab 86:1890-1897.