In vitro and in vivo biological activity screening of Ru(III) complexes involving 6-benzylaminopurine derivatives with higher pro-apoptotic activity than NAMI-A

Journal of Inorganic Biochemistry

Volumn 105, Issue 7, 2011, Pages 937-948

  Trávníček, Zdeněk ^a   Matiková Maľarová, Miroslava ^a   Novotná, Radka ^a   Vančo, Ján ^a   Štěpánková, Kamila ^a   Suchý, Pavel ^b  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

Author keywords

Antiradical activity; Crystal structure; In vitro cytotoxicity; In vivo antitumor activity; Purine derivatives; Ruthenium(III) complexes

Indexed keywords

6 N BENZYLADENINE; ANTINEOPLASTIC AGENT; DIMETHYL SULFOXIDE; NAMI A; PURINE DERIVATIVE; RUTHENIUM COMPLEX; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATOM; CANCER CELL CULTURE; CANCER TISSUE; CONDUCTANCE; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; LEUKEMIA; LEUKOCYTIC LEUKEMIA; MAGNETISM; MOUSE; NONHUMAN; PROTON TRANSPORT; RAMAN SPECTROMETRY; TAUTOMER; THERMAL ANALYSIS; ULTRAVIOLET SPECTROSCOPY; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; DIMETHYL SULFOXIDE; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; KINETIN; LEUKEMIA L1210; MICE; MICE, INBRED DBA; MITOSIS; MOLECULAR CONFORMATION; NECROSIS; NEOPLASM TRANSPLANTATION; ORGANOMETALLIC COMPOUNDS; RUTHENIUM;

EID: 79955386116     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2011.04.002     Document Type: Article

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