Enhancement and degradation of the R 2 * relaxation rate resulting from the encapsulation of magnetic particles with hydrophilic coatings

Magnetic Resonance in Medicine

Volumn 66, Issue 6, 2011, Pages 1759-1766

  De Haan, Hendrick W ^a   Paquet, Chantal ^b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

hydrogel; hyrophilic coating; MRI constrast agent; polymer coated superparamagnetic nanoparticles

Indexed keywords

HYDROGELS; HYDROPHILICITY; MONTE CARLO METHODS; PARTICLE SIZE;

CONSTRAST AGENT; DEPHASING PROCESS; HYDROPHILIC COATINGS; MAGNETIC PARTICLE; PHYSICAL PICTURES; SMALL PARTICLE SIZE; SUPERPARAMAGNETIC NANOPARTICLES; TRANSITION PROBABILITIES;

DIFFUSION COATINGS;

CONTRAST MEDIUM; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; BIOMATERIAL; MAGNETITE NANOPARTICLE; PROTON;

ARTICLE; DEGRADATION; DIFFUSION COEFFICIENT; ENCAPSULATION; HYDROGEL; HYDROPHILICITY; MATERIAL COATING; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PROBABILITY; SURFACE PROPERTY; CHEMICAL MODEL; CHEMICAL PHENOMENA; CHEMISTRY; COMPUTER SIMULATION; MAGNETISM; MATERIALS TESTING; SPIN LABELING;

COATED MATERIALS, BIOCOMPATIBLE; COMPUTER SIMULATION; CONTRAST MEDIA; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAGNETICS; MAGNETITE NANOPARTICLES; MATERIALS TESTING; MODELS, CHEMICAL; PROTONS; SPIN LABELS;

EID: 79955373642     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22944     Document Type: Article

References (37)

1. Bautista MC, Bomati-Miguel O, Zhao X, Morales MP, Gonzalez-Carreno T, Alejo R, Ruiz-Cabello J, Veintemillas-Verdaguer S,. Comparative study of ferrofluids based on dextran-coated iron oxide and metal nanoparticles for contrast agents in magnetic resonance imaging. Nanotechnology 2004; 15: S154.
2. Huh YM, Jun Y, Song HT, Kim S, Choi J, Lee JH, Yoon S, Kim KS, Shin JS, Suh JS, Jinwoo C,. In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals. J Am Chem Soc 2005; 127: 12387-12391.
3. Qin J, Laurent S, Jo YS, Roch A, Mikhaylova M, Bhujwalla ZM, Muller RN, Muhammed M,. A high-performance magnetic resonance imaging T2 contrast agent. Adv Mater 2007; 19: 1874-1878.
4. Tsai ZT, Wang JF, Kuo HY, Shen CR, Wang JJ, Yen TC,. In situ preparation of high relaxivity iron oxide nanoparticles by coating with chitosan: A potential MRI contrast agent useful for cell tracking. J Magn Magn Mater 2010; 322: 208-213.
5. Fang C, Bhattarai N, Sun C, Zhang M,. Functionalized nanoparticles with long-term stability in biological media. Small 2009; 5: 1637-1641.
6. Ge J, Hu Y, Biasini M, Beyermann WP, Yin Y,. Superparamagnetic magnetite colloidal nanocrystal clusters. Angew Chem 2007; 46: 4342-4345.
7. Xu H, Cui L, Tong N, Gu H,. Development of high magnetization Fe3O4/polystyrene/silica nanospheres via combined miniemulsion/emulsion polymerization. J Am Chem Soc 2006; 128: 15582-15583.
8. Qiu P, Jensen C, Charity N, Towner R, Mao C,. Oil phase evaporation-induced self-assembly of hydrophobic nanoparticles into spherical clusters with controlled surface chemistry in an oil-in-water dispersion and comparison of behaviors of individual and clustered iron oxide nanoparticles. J Am Chem Soc 2010; 132: 17724-17732.
9. Paquet C, Pagé L, Kell A, Simard B,. Nanobeads highly loaded with superparamagnetic nanoparticles prepared by emulsification and seeded-emulsion polymerization. Langmuir 2010; 26: 5388-5396.
10. Berret JF, Schonbeck N, Gazeau F, El Kharrat D, Sandre O, Vacher A, Airiau M,. Controlled clustering of superparamagnetic nanoparticles using block copolymers: design of new contrast agents for magnetic resonance imaging. J Am Chem Soc 2006; 128: 1755-1761.
11. Hu F, MacRenaris KW, Waters EA, Schultz-Sikma EA, Eckermann AL, Meade TJ,. Highly dispersible, superparamagnetic magnetite nanoflowers for magnetic resonance imaging. Chem Comm 2010; 46: 73-75.
12. Ai H, Flask C, Weinberg B, Shuai X, Pagel MD, Farrell D, Duerk J, Gao J,. Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes. Adv Mater 2005; 17: 1949-1951.
13. Kim J, Kim HS, Lee N, Kim T, Kim H, Yu T, Song IC, Moon WK, Hyeon T,. Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew Chem 2008; 120: 8438-8441.
14. Liu G, Wang Z, Lu J, Xia C, Gao F, Gong Q, Song B, Zhao X, Shuai X, Chen X, Ai H, Gu Z,. Low molecular weight alkyl-polycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging. Biomaterials 2011; 32: 528-537.
15. Kaittanis C, Santra S, Perez JM,. Role of nanoparticle valency in the nondestructive magnetic-relaxation-mediated detection and magnetic isolation of cells in complex media. J Am Chem Soc 2009; 131: 12780-12791.
16. Perez JM, Josephson L, O'Loughlin T, Högemann D, Weissleder R,. Magnetic relaxation switches capable of sensing molecular interactions Nat Biotechnol 2002; 20: 816-820.
17. de Vries IJM, Lesterhuis WJ, Barentsz JO, Verdijk P, van Krieken JH, Boerman OC, Oyen WJG, Bonenkamp JJ, Boezeman JB, Adema GJ, Bulte JWM, Scheenen TWJ, Punt CJA, Heerschap A, Figdor CG,. Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 2005; 23: 1407-1413.
18. Zhu J, Zhou L, XingWu F, Tracking neural stem cells in patients with brain trauma. N Engl J Med 2006; 355: 2376-2378.
19. Chen DX, Sun N, Huang ZJ, Cheng CM, Xu H, Gu HC,. Experimental study on T2 relaxation time of protons in water suspensions of iron-oxide nanoparticles: Effects of polymer coating thickness and over-low 1/T2. J Magn Magn Mater 2010; 322: 548-556.
20. Chen DX, Sun N, Gu HC,. Size analysis of carboxydextran coated superparamagnetic iron oxide particles used as contrast agents of magnetic resonance imaging. J Appl Phys 2009; 106: 063906.
21. Duan H, Kuang M, Wang X, Wang YA, Mao H, Nie S,. Reexamining the effects of particle size and surface chemistry on the magnetic properties of iron oxide nanocrystals: new insights into spin disorder and proton relaxivity. J Phys Chem C 2008; 112: 8127-8131.
22. LaConte LEW, Nitin N, Zurkiya O, Caruntu D, O'Connor CJ, Hu X, Bao G,. Coating thickness of magnetic iron oxide nanoparticles affects R2 relaxivity. J Magn Reson Imaging 2007; 26: 1634-1641.
23. Pinho SLC, Pereira GA, Voisin P, Kassem J, Bouchaud V, Etienne L, Peters JA, Carlos L, Mornet S, Geraldes CFGC, Rocha J, Delville MH,. Fine tuning of the relaxometry of γ-Fe2O3@ SiO2 nanoparticles by tweaking the silica coating thickness. ACS Nano 4: 5339-5349.
24. Gillis P, Moiny F, Brooks RA,. On T2-shortening by strongly magnetized spheres: a partial refocusing model. Magn Reson Med 2002; 47: 257-263.
25. Brooks RA, Moiny F, Gillis P,. On T2-shortening by weakly magnetized particles: the chemical exchange model. Magn Reson Med 2001; 45: 1014-1020.
26. Brooks RA,. T2-shortening by strongly magnetized spheres: a chemical exchange model. Magn Reson Med 2002; 47: 388-391.
27. Yablonskiy DA, Haacke EM,. Theory of NMR signal behavior in magnetically inhomogeneous tissues: the static dephasing regime. Magn Reson Med 1994; 32: 749-763.
28. de Haan HW,. Mechanisms of proton spin dephasing in a system of magnetic particles. Magn Reson Med 2011 [Epub ahead of print].
29. Carroll MRJ, Woodward RC, House MJ, Teoh WY, Amal R, Hanley TL, Pierre TGS,. Experimental validation of proton transverse relaxivity models for superparamagnetic nanoparticle MRI contrast agents. Nanotechnology 2010; 21: 035103.
30. Kwak S, Lafleur M,. NMR self-diffusion of molecular and macromolecular species in dextran solutions and gels. Macromolecules 2003; 36: 3189-3195.
31. Penke B, Kinsey S, Gibbs SJ, Moerland TS, Locke BR,. Proton diffusion and T1 relaxation in polyacrylamide gels: a unified approach using volume averaging. J Magn Reson 1998; 132: 240-254.
32. Li B, Ding D, Sun P, Wang Y, Ma J, He B,. PGSE NMR studies of water states of hydrogel P(AmNaA). J Appl Polym Sci 2000; 77: 454-427.
33. Matsumoto Y, Jasanoff A,. T2 relaxation induced by clusters of superparamagnetic nanoparticles: Monte Carlo simulations. Magn Reson Imaging 2008; 26: 994-998.
34. Brown RJS,. Distribution of fields from randomly placed dipoles: free-precession signal decay as result of magnetic grains. Phys Rev 1961; 121: 1379-1382.
35. Hardy PA, Henkelman RM,. Transverse relaxation rate enhancement caused by magnetic particulates. Magn Reson Imaging 1989; 7: 265-275.
36. Weisskoff R, Zuo CS, Boxerman JL, Rosen BR,. Microscopic susceptibility variation and transverse relaxation: theory and experiment. Magn Reson Med 1994; 31: 601-610.
37. Boxerman JL, Hamberg LM, Rosen BR, Weisskoff RM,. MR contrast due to intravascular magnetic susceptibility perturbations. Magn Reson Med 1995; 34: 555-566.