Coating thickness of magnetic iron oxide nanoparticles affects R 2 relaxivity

Journal of Magnetic Resonance Imaging

Volumn 26, Issue 6, 2007, Pages 1634-1641

  LaConte, Leslie E W ^a   Nitin, Nitin ^a   Zurkiya, Omar ^a   Caruntu, Daniela ^b   O'Connor, Charles J ^b   Hu, Xiaoping ^a   Bao, Gang ^a  

^a Emory University   (United States)

^b UNIVERSITY OF NEW ORLEANS   (United States)

Author keywords

Coating thickness; Molecular imaging; MRI contrast agent; Relaxivity; Superparamagnetic nanoparticle

Indexed keywords

MACROGOL; MONOCRYSTALLINE IRON OXIDE NANOPARTICLE; NANOPARTICLE; PHOSPHOLIPID;

ARTICLE; COMPETITION; ELECTRON MICROSCOPY; LIGHT SCATTERING; MAGNETIC FIELD; MATERIAL COATING; MICELLE; MOLECULAR WEIGHT; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTON TRANSPORT; RELAXATION TIME; THICKNESS;

COMPUTER SIMULATION; CONTRAST MEDIA; FERRIC COMPOUNDS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE IMAGING; MICELLES; MONTE CARLO METHOD; NANOPARTICLES; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; SURFACE PROPERTIES;

EID: 37349128546     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.21194     Document Type: Article

References (34)

1. Wang YX, Hussain SM, Krestin GP. Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging. Eur Radiol 2001;11:2319-2331.
2. Bulte JW, Kraitchman DL. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed 2004;17:484-499.
3. Nitin N, LaConte LE, Zurkiya O, Hu X, Bao G. Functionalization and peptide-based delivery of magnetic nanoparticles as an intracellular MRI contrast agent. J Biol Inorg Chem 2004;9:706-712.
4. Shen T, Weissleder R, Papisov M, Bogdanov A, Jr, Brady TJ. Monocrystalline iron oxide nanocompounds (MION): physicochemical properties. Magn Reson Med 1993;29:599-604.
5. Butterworth MD, Ilium L, Davis SS. Preparation of ultrafine silica-and PEG-coated magnetite particles. Colloids Surf A Physicochem Eng Asp 2001;179:93-102.
6. Josephson L, Tung CH, Moore A, Weissleder R. High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates. Bioconjug Chem 1999;10:186-191.
7. Kim DK, Mikhaylova M, Zhang Y, Muhammed M. Protective coating of superparamagnetic iron oxide nanoparticles. Chem Mater 2003;15:1617-1627.
8. Liu Q, Xu Z. Self-assembled monolayer coatings on nanosized magnetic particles using 16-mercaptohexadecanoic acid. Langmuir 1995;11:4617-4622.
9. Paul KG, Frigo TB, Groman JY, Groman EV. Synthesis of ultrasmall superparamagnetic iron oxides using reduced polysaccharides. Bioconjug Chem 2004;15:394-401.
10. Jones M, Leroux J. Polymeric micelles - a new generation of colloidal drug carriers. Eur J Pharm Biopharm 1999;48:101-111.
11. Torchilin VP. PEG-based micelles as carriers of contrast agents for different imaging modalities. Adv Drug Deliv Rev 2002;54:235-252.
12. Mulder WJ, Strijkers GJ, van Tilborg GA, Griffioen AW, Nicolay K. Lipid-based nanoparticles for contrast-enhanced MRI and molecular imaging. NMR Biomed 2006;19:142-164.
13. van Tilborg GA, Mulder WJ, Chin PT, et al. Annexin A5-conjugated quantum dots with a paramagnetic lipidic coating for the multimodal detection of apoptotic cells. Bioconjug Chem 2006;17:865-868.
14. Feltin N, Pileni MP. New technique for synthesizing iron ferrite magnetic nanosized particles. Langmuir 1997;13:3927-3933.
15. Seip CT, O'Connor CJ. The fabrication and organization of self-assembled metallic nanoparticles formed in reverse micelles. Nanostructured Mater 1999;12:183-186.
16. Gillis P, Moiny F, Brooks RA. On T(2)-shortening by strongly magnetized spheres: a partial refocusing model. Magn Reson Med 2002;47:257-263.
17. Weisskoff RM, Zuo CS, Boxerman JL, Rosen BR. Microscopic susceptibility variation and transverse relaxation: theory and experiment. Magn Reson Med 1994;31:601-610.
18. Vergara A, Paduano L, Vitagliano V, Sartorio R. Mutual diffusion in aqueous solution of poly(ethyleneglycol) samples. Some comments on the effect of chain length and polydispersity. Phys Chem Chem Phys 1999;1:5377-5383.
19. Arleth L, Ashok B, Onyuksel H, Thiyagarajan P, Jacob J, Hjelm RP. Detailed structure of hairy mixed micelles formed by phosphatidylcholine and PEGylated phospholipids in aqueous media. Langmuir 2005;21:3279-3290.
20. Johnsson M, Hansson P, Edwards K. Spherical micelles and other self-assembled structures in dilute aqueous mixtures of poly(ethylene glycol) lipids. J Phys Chem B 2001;105:8420-8430.
21. Tscharnuter W. Photon correlation spectroscopy in particle sizing. In: Meyers RA, editor. Encyclopedia of analytical chemistry. Chichester: John Wiley & Sons Ltd.; 2000. p 5469-5485.
22. Sadeghi MM, Schechner JS, Krassilnikova S, et al. Vascular cell adhesion molecule-1-targeted detection of endothelial activation in human microvasculature. Transplant Proc 2004;36:1585-1591.
23. Saul JM, Annapragada A, Natarajan JV, Bellamkonda RV. Controlled targeting of liposomal doxorubicin via the folate receptor in vitro. J Control Release 2003;92:49-67.
24. Blankenberg FG, Strauss HW. Nuclear medicine applications in molecular imaging. J Magn Reson Imaging 2002;16:352-361.
25. Kellar KE, Fujii DK, Gunther WH, et al. Important considerations in the design of iron oxide nanoparticles as contrast agents for TI-weighted MRI and MRA. Acad Radiol 2002;9(Suppl 1):S34-S37.
26. Kellar KE, Fujii DK, Gunther WH, et al. NC100150 Injection, a preparation of optimized iron oxide nanoparticles for positive-contrast MR angiography. J Magn Reson Imaging 2000;11:488-494.
27. Clarkson RB. Blood-pool MRI contrast agents: properties and characterization. In: Kraus W, editor. Contrast agents 1: magnetic resonance imaging. Volume 221, Topics in current chemistry. Berlin Heidelberg: Springer-Verlag; 2002. p 202-235.
28. Corot C, Violas X, Robert P, Gagneur G, Port M. Comparison of different types of blood pool agents (P792, MS325, USPIO) in a rabbit MR angiography-like protocol. Invest Radiol 2003;38:311-319.
29. Koenig SH, Kellar KE. Blood-pool contrast agents for MRI: a critical evaluation. Acad Radiol 1998;5(Suppl 1):S200-S205; discussion S226-S207.
30. Knollmann FD, Bock JC, Rautenberg K, Beier J, Ebert W, Felix R. Differences in predominant enhancement mechanisms of super-paramagnetic iron oxide and ultrasmall superparamagnetic iron oxide for contrast-enhanced portal magnetic resonance angiography. Preliminary results of an animal study original investigation. Invest Radiol 1998;33:637-643.
31. Gossuin Y, Roch A, Lo Bue F, Muller RN, Gillis P. Nuclear magnetic relaxation dispersion of ferritin and ferritin-like magnetic particle solutions: a pH-effect study. Magn Reson Med 2001;46:476-481.
32. Gillis P, Koenig SH. Transverse relaxation of solvent protons induced by magnetized spheres: application to ferritin, erythrocytes, and magnetite. Magn Reson Med 1987;5:323-345.
33. Koenig SH, Kellar KE. Theory of 1/T1 and 1/T2 NMRD profiles of solutions of magnetic nanoparticles. Magn Reson Med 1995;34:227-233.
34. Mohs AM, Zong Y, Guo J, Parker DL, Lu ZR. PEG-g-poly(GdDTPA-co-L-cystine) : effect of PEG chain length on in vivo contrast enhancement in MRI. Biomacromolecules 2005;6:2305-2311.