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Volumn 23, Issue 5, 2011, Pages 239-248

Hypertension treatment update: Focus on direct renin inhibition

Author keywords

Aliskiren; Combination therapy; Direct renin inhibitor; Epidemiology; Hypertension; Pathophysiology; Renin angiotensin aldosterone system

Indexed keywords

ALISKIREN; AMIDE; ANTIHYPERTENSIVE AGENT; FUMARIC ACID DERIVATIVE; RENIN;

EID: 79955141059     PISSN: 10412972     EISSN: 17457599     Source Type: Journal    
DOI: 10.1111/j.1745-7599.2010.00589.x     Document Type: Review
Times cited : (10)

References (77)
  • 1
    • 24044536393 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: A meta-analysis of randomized clinical trials
    • Abuissa, H., Jones, P. G., Marso, S. P., & O'Keefe, J. H., Jr. (2005). Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: A meta-analysis of randomized clinical trials. Journal of the American College of Cardiology, 46(5), 821-826.
    • (2005) Journal of the American College of Cardiology , vol.46 , Issue.5 , pp. 821-826
    • Abuissa, H.1    Jones, P.G.2    Marso, S.P.3    O'Keefe Jr, J.H.4
  • 2
    • 0034641550 scopus 로고    scopus 로고
    • Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): Prospective observational study
    • Adler, A. I., Stratton, I. M., Neil, H. A., Yudkin, J. S., Matthews, D. R., Cull, C. A., et al. (2000). Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): Prospective observational study. British Medical Journal, 321(7258), 412-419.
    • (2000) British Medical Journal , vol.321 , Issue.7258 , pp. 412-419
    • Adler, A.I.1    Stratton, I.M.2    Neil, H.A.3    Yudkin, J.S.4    Matthews, D.R.5    Cull, C.A.6
  • 4
    • 2642575030 scopus 로고    scopus 로고
    • Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists
    • Azizi, M., & Menard, J. (2004). Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists. Circulation, 109(21), 2492-2499.
    • (2004) Circulation , vol.109 , Issue.21 , pp. 2492-2499
    • Azizi, M.1    Menard, J.2
  • 5
    • 33644789557 scopus 로고    scopus 로고
    • Renin inhibition with aliskiren: Where are we now, and where are we going?
    • Azizi, M., Webb, R., Nussberger, J., & Hollenberg, N. K. (2006). Renin inhibition with aliskiren: Where are we now, and where are we going? Journal of Hypertension, 24(2), 243-256.
    • (2006) Journal of Hypertension , vol.24 , Issue.2 , pp. 243-256
    • Azizi, M.1    Webb, R.2    Nussberger, J.3    Hollenberg, N.K.4
  • 6
    • 0033852481 scopus 로고    scopus 로고
    • Preserving renal function in adults with hypertension and diabetes: A consensus approach
    • National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group.
    • Bakris, G. L., Williams, M., Dworkin, L., Elliott, W. J., Epstein, M., Toto, R., et al., National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group. (2000). Preserving renal function in adults with hypertension and diabetes: A consensus approach. American Journal of Kidney Diseases, 36(3), 646-661.
    • (2000) American Journal of Kidney Diseases , vol.36 , Issue.3 , pp. 646-661
    • Bakris, G.L.1    Williams, M.2    Dworkin, L.3    Elliott, W.J.4    Epstein, M.5    Toto, R.6
  • 8
    • 51449099674 scopus 로고    scopus 로고
    • Beta-blockers for primary prevention of heart failure in patients with hypertension insights from a meta-analysis
    • Bangalore, S., Wild, D., Parkar, S., Kukin, M., & Messerli, F. H. (2008). Beta-blockers for primary prevention of heart failure in patients with hypertension insights from a meta-analysis. Journal of the American College of Cardiology, 52(13), 1062-1072.
    • (2008) Journal of the American College of Cardiology , vol.52 , Issue.13 , pp. 1062-1072
    • Bangalore, S.1    Wild, D.2    Parkar, S.3    Kukin, M.4    Messerli, F.H.5
  • 9
    • 33750999057 scopus 로고    scopus 로고
    • Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: A report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    • Barzilay, J. I., Davis, B. R., Cutler, J. A., Pressel, S. L., Whelton, P. K., Basile, J., et al. (2006). Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: A report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Archives of Internal Medicine, 166(20), 2191-2201.
    • (2006) Archives of Internal Medicine , vol.166 , Issue.20 , pp. 2191-2201
    • Barzilay, J.I.1    Davis, B.R.2    Cutler, J.A.3    Pressel, S.L.4    Whelton, P.K.5    Basile, J.6
  • 11
    • 5544244681 scopus 로고    scopus 로고
    • Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled
    • Bramlage, P., Pittrow, D., Wittchen, H. U., Kirch, W., Boehler, S., Lehnert, H., et al. (2004). Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled. American Journal of Hypertension, 17(10), 904-910.
    • (2004) American Journal of Hypertension , vol.17 , Issue.10 , pp. 904-910
    • Bramlage, P.1    Pittrow, D.2    Wittchen, H.U.3    Kirch, W.4    Boehler, S.5    Lehnert, H.6
  • 12
    • 0036951359 scopus 로고    scopus 로고
    • Remission of renal disease: Recounting the challenge, acquiring the goal
    • Brenner, B. M. (2002). Remission of renal disease: Recounting the challenge, acquiring the goal. Journal of Clinical Investigation, 110(12), 1753-1758.
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.12 , pp. 1753-1758
    • Brenner, B.M.1
  • 13
    • 38549092093 scopus 로고    scopus 로고
    • Aldosterone and vascular inflammation
    • Brown, N. J. (2008). Aldosterone and vascular inflammation. Hypertension, 51(2), 161-167.
    • (2008) Hypertension , vol.51 , Issue.2 , pp. 161-167
    • Brown, N.J.1
  • 15
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jr., et al. (2003). Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension, 42(6), 1206-1252.
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo Jr, J.L.6
  • 16
    • 34548840822 scopus 로고    scopus 로고
    • Clinical trials update from the European Society of Cardiology Congress 2007: 3CPO, ALOFT, PROSPECT and statins for heart failure
    • Cleland, J. G., Abdellah, A. T., Khaleva, O., Coletta, A. P., & Clark, A. L. (2007). Clinical trials update from the European Society of Cardiology Congress 2007: 3CPO, ALOFT, PROSPECT and statins for heart failure. European Journal of Heart Failure, 9(10), 1070-1073.
    • (2007) European Journal of Heart Failure , vol.9 , Issue.10 , pp. 1070-1073
    • Cleland, J.G.1    Abdellah, A.T.2    Khaleva, O.3    Coletta, A.P.4    Clark, A.L.5
  • 17
    • 47649084109 scopus 로고    scopus 로고
    • Thiazide-type diuretics and beta-adrenergic blockers as first-line drug treatments for hypertension
    • Cutler, J. A., & Davis, B. R. (2008). Thiazide-type diuretics and beta-adrenergic blockers as first-line drug treatments for hypertension. Circulation, 117(20), 2691-2704.
    • (2008) Circulation , vol.117 , Issue.20 , pp. 2691-2704
    • Cutler, J.A.1    Davis, B.R.2
  • 18
    • 0037160968 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint Reduction in Hypertension study (LIFE): A randomised trial against atenolol
    • Dahlof, B., Devereux, R. B., Kjeldsen, S. E., Julius, S., Beevers, G., de Faire, U., et al. (2002). Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint Reduction in Hypertension study (LIFE): A randomised trial against atenolol. Lancet, 359(9311), 995-1003.
    • (2002) Lancet , vol.359 , Issue.9311 , pp. 995-1003
    • Dahlof, B.1    Devereux, R.B.2    Kjeldsen, S.E.3    Julius, S.4    Beevers, G.5    de Faire, U.6
  • 20
    • 0035048905 scopus 로고    scopus 로고
    • Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: A unifying hypothesis
    • Dzau, V. J. (2001). Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: A unifying hypothesis. Hypertension, 37(4), 1047-1052.
    • (2001) Hypertension , vol.37 , Issue.4 , pp. 1047-1052
    • Dzau, V.J.1
  • 21
    • 68549118943 scopus 로고    scopus 로고
    • Thiazide effects and adverse effects: Insights from molecular genetics
    • Ellison, D. H., & Loffing, J. (2009). Thiazide effects and adverse effects: Insights from molecular genetics. Hypertension, 54(2), 196-202.
    • (2009) Hypertension , vol.54 , Issue.2 , pp. 196-202
    • Ellison, D.H.1    Loffing, J.2
  • 22
    • 0034896157 scopus 로고    scopus 로고
    • Aldosterone as a determinant of cardiovascular and renal dysfunction
    • Epstein, M. (2001). Aldosterone as a determinant of cardiovascular and renal dysfunction. Journal of the Royal Society of Medicine, 94(8), 378-383.
    • (2001) Journal of the Royal Society of Medicine , vol.94 , Issue.8 , pp. 378-383
    • Epstein, M.1
  • 23
    • 0034651798 scopus 로고    scopus 로고
    • Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • Farquharson, C. A., & Struthers, A. D. (2000). Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation, 101(6), 594-597.
    • (2000) Circulation , vol.101 , Issue.6 , pp. 594-597
    • Farquharson, C.A.1    Struthers, A.D.2
  • 24
    • 0036865453 scopus 로고    scopus 로고
    • Sexual dysfunction in patients with hypertension: Implications for therapy
    • Ferrario, C. M., & Levy, P. (2002). Sexual dysfunction in patients with hypertension: Implications for therapy. J Clin Hypertens (Greenwich), 4(6), 424-432.
    • (2002) J Clin Hypertens (Greenwich) , vol.4 , Issue.6 , pp. 424-432
    • Ferrario, C.M.1    Levy, P.2
  • 26
    • 33947194473 scopus 로고    scopus 로고
    • The efficacy of aliskiren, a direct renin inhibitor, in the treatment of hypertension
    • Gradman, A. H., & Traub, D. (2007). The efficacy of aliskiren, a direct renin inhibitor, in the treatment of hypertension. Reviews in Cardiovascular Medicine, 8(Suppl. 2), S22-S30.
    • (2007) Reviews in Cardiovascular Medicine , vol.8 , Issue.SUPPL. 2
    • Gradman, A.H.1    Traub, D.2
  • 27
    • 0041885190 scopus 로고    scopus 로고
    • Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: Results of the CROSS study
    • Grassi, G., Seravalle, G., Dell'Oro, R., Trevano, F. Q., Bombelli, M., Scopelliti, F., et al. (2003). Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: Results of the CROSS study. Journal of Hypertension, 21(9), 1761-1769.
    • (2003) Journal of Hypertension , vol.21 , Issue.9 , pp. 1761-1769
    • Grassi, G.1    Seravalle, G.2    Dell'Oro, R.3    Trevano, F.Q.4    Bombelli, M.5    Scopelliti, F.6
  • 28
    • 0031688757 scopus 로고    scopus 로고
    • Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system
    • Hollenberg, N. K., Fisher, N. D., & Price, D. A. (1998). Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system. Hypertension, 32(3), 387-392.
    • (1998) Hypertension , vol.32 , Issue.3 , pp. 387-392
    • Hollenberg, N.K.1    Fisher, N.D.2    Price, D.A.3
  • 29
    • 0031893657 scopus 로고    scopus 로고
    • Effects of combination therapy with an angiotensin converting enzyme inhibitor and thiazide diuretic on insulin action in essential hypertension
    • Hunter, S. J., Harper, R., Ennis, C. N., Crothers, E., Sheridan, B., Johnston, G. D., et al. (1998). Effects of combination therapy with an angiotensin converting enzyme inhibitor and thiazide diuretic on insulin action in essential hypertension. Journal of Hypertension, 16(1), 103-109.
    • (1998) Journal of Hypertension , vol.16 , Issue.1 , pp. 103-109
    • Hunter, S.J.1    Harper, R.2    Ennis, C.N.3    Crothers, E.4    Sheridan, B.5    Johnston, G.D.6
  • 30
    • 57349138291 scopus 로고    scopus 로고
    • Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients
    • Jamerson, K., Weber, M. A., Bakris, G. L., Dahlof, B., Pitt, B., Shi, V., et al. (2008). Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. New England Journal of Medicine, 359(23), 2417-2428.
    • (2008) New England Journal of Medicine , vol.359 , Issue.23 , pp. 2417-2428
    • Jamerson, K.1    Weber, M.A.2    Bakris, G.L.3    Dahlof, B.4    Pitt, B.5    Shi, V.6
  • 31
    • 40949091094 scopus 로고    scopus 로고
    • Prompt, aggressive BP lowering in high-risk patients
    • Jamerson, K. A., & Basile, J. (2008). Prompt, aggressive BP lowering in high-risk patients. Journal of Clinical Hypertension, 10(1 Suppl. 1), 40-48.
    • (2008) Journal of Clinical Hypertension , vol.10 SUPPL. 1 , Issue.1 , pp. 40-48
    • Jamerson, K.A.1    Basile, J.2
  • 32
    • 18844449196 scopus 로고    scopus 로고
    • Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes
    • Jandeleit-Dahm, K. A., Tikellis, C., Reid, C. M., Johnston, C. I., & Cooper, M. E. (2005). Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes. Journal of Hypertension, 23(3), 463-473.
    • (2005) Journal of Hypertension , vol.23 , Issue.3 , pp. 463-473
    • Jandeleit-Dahm, K.A.1    Tikellis, C.2    Reid, C.M.3    Johnston, C.I.4    Cooper, M.E.5
  • 33
    • 33845760213 scopus 로고    scopus 로고
    • KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease.
    • KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease. (2007). American Journal of Kidney Diseases, 49(2 Suppl. 2), S12-S154.
    • (2007) American Journal of Kidney Diseases , vol.49 SUPPL. 2 , Issue.2
  • 34
    • 0037490085 scopus 로고    scopus 로고
    • Value of low dose combination treatment with blood pressure lowering drugs: Analysis of 354 randomised trials
    • Law, M. R., Wald, N. J., Morris, J. K., & Jordan, R. E. (2003). Value of low dose combination treatment with blood pressure lowering drugs: Analysis of 354 randomised trials. British Medical Journal, 326(7404), 1427-1434.
    • (2003) British Medical Journal , vol.326 , Issue.7404 , pp. 1427-1434
    • Law, M.R.1    Wald, N.J.2    Morris, J.K.3    Jordan, R.E.4
  • 35
    • 33845450660 scopus 로고    scopus 로고
    • Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: A randomized controlled trial
    • Lee, J. K., Grace, K. A., & Taylor, A. J. (2006). Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: A randomized controlled trial. Journal of the American Medical Association, 296(21), 2563-2571.
    • (2006) Journal of the American Medical Association , vol.296 , Issue.21 , pp. 2563-2571
    • Lee, J.K.1    Grace, K.A.2    Taylor, A.J.3
  • 36
    • 27544463207 scopus 로고    scopus 로고
    • Should beta blockers remain first choice in the treatment of primary hypertension? A meta-analysis
    • Lindholm, L. H., Carlberg, B., & Samuelsson, O. (2005). Should beta blockers remain first choice in the treatment of primary hypertension? A meta-analysis. Lancet, 366(9496), 1545-1553.
    • (2005) Lancet , vol.366 , Issue.9496 , pp. 1545-1553
    • Lindholm, L.H.1    Carlberg, B.2    Samuelsson, O.3
  • 37
    • 27944473983 scopus 로고    scopus 로고
    • The Felodipine Event Reduction (FEVER) Study: A randomized long-term placebo-controlled trial in Chinese hypertensive patients
    • Liu, L., Zhang, Y., Liu, G., Li, W., Zhang, X., & Zanchetti, A. (2005). The Felodipine Event Reduction (FEVER) Study: A randomized long-term placebo-controlled trial in Chinese hypertensive patients. Journal of Hypertension, 23(12), 2157-2172.
    • (2005) Journal of Hypertension , vol.23 , Issue.12 , pp. 2157-2172
    • Liu, L.1    Zhang, Y.2    Liu, G.3    Li, W.4    Zhang, X.5    Zanchetti, A.6
  • 38
    • 79955140318 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2009 update. A Report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation.
    • Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., et al. (2008). Heart disease and stroke statistics-2009 update. A Report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation
    • (2008)
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3    De Simone, G.4    Ferguson, T.B.5    Flegal, K.6
  • 40
    • 34547615709 scopus 로고    scopus 로고
    • 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • Mancia, G., De Backer, G., Dominiczak, A., Cifkova, R., Fagard, R., Germano, G., et al. (2007). 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 28(12), 1462-1536.
    • (2007) European Heart Journal , vol.28 , Issue.12 , pp. 1462-1536
    • Mancia, G.1    De Backer, G.2    Dominiczak, A.3    Cifkova, R.4    Fagard, R.5    Germano, G.6
  • 41
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • Mann, J. F., Schmieder, R. E., McQueen, M., Dyal, L., Schumacher, H., Pogue, J., et al. (2008). Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial. Lancet, 372(9638), 547-553.
    • (2008) Lancet , vol.372 , Issue.9638 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3    Dyal, L.4    Schumacher, H.5    Pogue, J.6
  • 42
    • 17044377817 scopus 로고    scopus 로고
    • Self-reported hypertension treatment beliefs and practices of primary care physicians in a managed care organization
    • Margolis, K. L., Rolnick, S. J., Fortman, K. K., Maciosek, M. V., Hildebrant, C. L., & Grimm, R. H., Jr. (2005). Self-reported hypertension treatment beliefs and practices of primary care physicians in a managed care organization. American Journal of Hypertension, 18(4 Pt. 1), 566-571.
    • (2005) American Journal of Hypertension , vol.18 , Issue.4 PART 1 , pp. 566-571
    • Margolis, K.L.1    Rolnick, S.J.2    Fortman, K.K.3    Maciosek, M.V.4    Hildebrant, C.L.5    Grimm Jr, R.H.6
  • 43
    • 61849099349 scopus 로고    scopus 로고
    • Simplification strategies to reduce antiretroviral drug exposure: Progress and prospects
    • McKinnon, J. E., Mellors, J. W., & Swindells, S. (2009). Simplification strategies to reduce antiretroviral drug exposure: Progress and prospects. Antiviral Therapy, 14(1), 1-12.
    • (2009) Antiviral Therapy , vol.14 , Issue.1 , pp. 1-12
    • McKinnon, J.E.1    Mellors, J.W.2    Swindells, S.3
  • 44
    • 58949097006 scopus 로고    scopus 로고
    • The sudden demise of dual renin-angiotensin system blockade or the soft science of the surrogate end point
    • Messerli, F. H. (2009). The sudden demise of dual renin-angiotensin system blockade or the soft science of the surrogate end point. Journal of the American College of Cardiology, 53(6), 468-470.
    • (2009) Journal of the American College of Cardiology , vol.53 , Issue.6 , pp. 468-470
    • Messerli, F.H.1
  • 45
    • 60549111958 scopus 로고    scopus 로고
    • Antihypertensive efficacy of aliskiren: Is hydrochlorothiazide an appropriate benchmark?
    • Messerli, F. H., & Bangalore, S. (2009). Antihypertensive efficacy of aliskiren: Is hydrochlorothiazide an appropriate benchmark? Circulation, 119(3), 371-373.
    • (2009) Circulation , vol.119 , Issue.3 , pp. 371-373
    • Messerli, F.H.1    Bangalore, S.2
  • 46
    • 47649085694 scopus 로고    scopus 로고
    • Risk/benefit assessment of beta-blockers and diuretics precludes their use for first-line therapy in hypertension
    • Messerli, F. H., Bangalore, S., & Julius, S. (2008). Risk/benefit assessment of beta-blockers and diuretics precludes their use for first-line therapy in hypertension. Circulation, 117(20), 2706-2715.
    • (2008) Circulation , vol.117 , Issue.20 , pp. 2706-2715
    • Messerli, F.H.1    Bangalore, S.2    Julius, S.3
  • 47
    • 33644833746 scopus 로고    scopus 로고
    • Efficacy of combination therapy for systolic blood pressure in patients with severe systolic hypertension: The Systolic Evaluation of Lotrel Efficacy and Comparative Therapies (SELECT) study
    • Neutel, J. M., Smith, D. H., Weber, M. A., Schofield, L., Purkayastha, D., & Gatlin, M. (2005). Efficacy of combination therapy for systolic blood pressure in patients with severe systolic hypertension: The Systolic Evaluation of Lotrel Efficacy and Comparative Therapies (SELECT) study. Journal of Clinical Hypertension, 7(11), 641-646.
    • (2005) Journal of Clinical Hypertension , vol.7 , Issue.11 , pp. 641-646
    • Neutel, J.M.1    Smith, D.H.2    Weber, M.A.3    Schofield, L.4    Purkayastha, D.5    Gatlin, M.6
  • 48
    • 0036372173 scopus 로고    scopus 로고
    • Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): Comparison with enalapril
    • Nussberger, J., Wuerzner, G., Jensen, C., & Brunner, H. R. (2002). Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): Comparison with enalapril. Hypertension, 39(1), E1-8.
    • (2002) Hypertension , vol.39 , Issue.1
    • Nussberger, J.1    Wuerzner, G.2    Jensen, C.3    Brunner, H.R.4
  • 49
    • 33847633400 scopus 로고    scopus 로고
    • Prevalence, awareness, treatment, and control of hypertension among United States adults 1999-2004
    • Ong, K. L., Cheung, B. M., Man, Y. B., Lau, C. P., & Lam, K. S. (2007). Prevalence, awareness, treatment, and control of hypertension among United States adults 1999-2004. Hypertension, 49(1), 69-75.
    • (2007) Hypertension , vol.49 , Issue.1 , pp. 69-75
    • Ong, K.L.1    Cheung, B.M.2    Man, Y.B.3    Lau, C.P.4    Lam, K.S.5
  • 51
    • 3442888821 scopus 로고    scopus 로고
    • Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system
    • Palmer, B. F. (2004). Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system. New England Journal of Medicine, 351(6), 585-592.
    • (2004) New England Journal of Medicine , vol.351 , Issue.6 , pp. 585-592
    • Palmer, B.F.1
  • 54
    • 34548420712 scopus 로고    scopus 로고
    • Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial
    • Patel, A., MacMahon, S., Chalmers, J., Neal, B., Woodward, M., Billot, L., et al. (2007). Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial. Lancet, 370(9590), 829-840.
    • (2007) Lancet , vol.370 , Issue.9590 , pp. 829-840
    • Patel, A.1    MacMahon, S.2    Chalmers, J.3    Neal, B.4    Woodward, M.5    Billot, L.6
  • 55
    • 0242490542 scopus 로고    scopus 로고
    • Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
    • Pfeffer, M. A., McMurray, J. J., Velazquez, E. J., Rouleau, J. L., Kober, L., Maggioni, A. P., et al. (2003). Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. New England Journal of Medicine, 349(20), 1893-1906.
    • (2003) New England Journal of Medicine , vol.349 , Issue.20 , pp. 1893-1906
    • Pfeffer, M.A.1    McMurray, J.J.2    Velazquez, E.J.3    Rouleau, J.L.4    Kober, L.5    Maggioni, A.P.6
  • 56
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt, B., Remme, W., Zannad, F., Neaton, J., Martinez, F., Roniker, B., et al. (2003). Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. New England Journal of Medicine, 348(14), 1309-1321.
    • (2003) New England Journal of Medicine , vol.348 , Issue.14 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3    Neaton, J.4    Martinez, F.5    Roniker, B.6
  • 57
    • 0024428292 scopus 로고
    • A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension
    • Pollare, T., Lithell, H., & Berne, C. (1989). A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. New England Journal of Medicine, 321(13), 868-873.
    • (1989) New England Journal of Medicine , vol.321 , Issue.13 , pp. 868-873
    • Pollare, T.1    Lithell, H.2    Berne, C.3
  • 58
    • 0345377486 scopus 로고    scopus 로고
    • Is it time to move to multidrug combinations?
    • Pool, J. L. (2003). Is it time to move to multidrug combinations? American Journal of Hypertension, 16(11 Pt. 2), 36S-40S.
    • (2003) American Journal of Hypertension , vol.16 , Issue.11 PART. 2
    • Pool, J.L.1
  • 59
    • 0033989542 scopus 로고    scopus 로고
    • Clinical implications of increased plasma angiotensin II despite ACE inhibitor therapy in patients with congestive heart failure
    • Roig, E., Perez-Villa, F., Morales, M., Jimenez, W., Orus, J., Heras, M., et al. (2000). Clinical implications of increased plasma angiotensin II despite ACE inhibitor therapy in patients with congestive heart failure. European Heart Journal, 21(1), 53-57.
    • (2000) European Heart Journal , vol.21 , Issue.1 , pp. 53-57
    • Roig, E.1    Perez-Villa, F.2    Morales, M.3    Jimenez, W.4    Orus, J.5    Heras, M.6
  • 60
    • 34249655660 scopus 로고    scopus 로고
    • Treatment of hypertension in the prevention and management of ischemic heart disease: Ascientific statement from the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention
    • Rosendorff, C., Black, H. R., Cannon, C. P., Gersh, B. J., Gore, J., Izzo, J. L., Jr., et al. (2007). Treatment of hypertension in the prevention and management of ischemic heart disease: Ascientific statement from the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention. Circulation, 115(21), 2761-2788.
    • (2007) Circulation , vol.115 , Issue.21 , pp. 2761-2788
    • Rosendorff, C.1    Black, H.R.2    Cannon, C.P.3    Gersh, B.J.4    Gore, J.5    Izzo Jr, J.L.6
  • 61
    • 34047121150 scopus 로고    scopus 로고
    • Renin-angiotensin system and cardiovascular risk
    • Schmieder, R. E., Hilgers, K. F., Schlaich, M. P., & Schmidt, B. M. (2007). Renin-angiotensin system and cardiovascular risk. Lancet, 369(9568), 1208-1219.
    • (2007) Lancet , vol.369 , Issue.9568 , pp. 1208-1219
    • Schmieder, R.E.1    Hilgers, K.F.2    Schlaich, M.P.3    Schmidt, B.M.4
  • 62
    • 60549087324 scopus 로고    scopus 로고
    • Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: A 12-month randomized, double-blind comparator trial with hydrochlorothiazide
    • Schmieder, R. E., Philipp, T., Guerediaga, J., Gorostidi, M., Smith, B., Weissbach, N., et al. (2009). Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: A 12-month randomized, double-blind comparator trial with hydrochlorothiazide. Circulation, 119(3), 417-425.
    • (2009) Circulation , vol.119 , Issue.3 , pp. 417-425
    • Schmieder, R.E.1    Philipp, T.2    Guerediaga, J.3    Gorostidi, M.4    Smith, B.5    Weissbach, N.6
  • 64
    • 0036189466 scopus 로고    scopus 로고
    • Rationale for fixed-dose combinations in the treatment of hypertension: The cycle repeats
    • Sica, D. A. (2002). Rationale for fixed-dose combinations in the treatment of hypertension: The cycle repeats. Drugs, 62(3), 443-462.
    • (2002) Drugs , vol.62 , Issue.3 , pp. 443-462
    • Sica, D.A.1
  • 65
    • 2942750248 scopus 로고    scopus 로고
    • Identifying gaps between guidelines and clinical practice in the evaluation and treatment of patients with hypertension
    • Spranger, C. B., Ries, A. J., Berge, C. A., Radford, N. B., & Victor, R. G. (2004). Identifying gaps between guidelines and clinical practice in the evaluation and treatment of patients with hypertension. American Journal of Medicine, 117(1), 14-18.
    • (2004) American Journal of Medicine , vol.117 , Issue.1 , pp. 14-18
    • Spranger, C.B.1    Ries, A.J.2    Berge, C.A.3    Radford, N.B.4    Victor, R.G.5
  • 66
    • 0347479295 scopus 로고    scopus 로고
    • Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren
    • Stanton, A., Jensen, C., Nussberger, J., & O'Brien, E. (2003). Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren. Hypertension, 42(6), 1137-1143.
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1137-1143
    • Stanton, A.1    Jensen, C.2    Nussberger, J.3    O'Brien, E.4
  • 67
    • 79955166424 scopus 로고    scopus 로고
    • Association between baseline levels of plasma renin activity and risk of cardiovascular events. Paper presented at the American College of Cardiology, Orlando, Fl.
    • Tami, L., Bair, H. T., May, M., Prescott, F., Anderson, J. L., Horne, B. D., et al. (2009). Association between baseline levels of plasma renin activity and risk of cardiovascular events. Paper presented at the American College of Cardiology, Orlando, Fl
    • (2009)
    • Tami, L.1    Bair, H.T.2    May, M.3    Prescott, F.4    Anderson, J.L.5    Horne, B.D.6
  • 68
    • 0031944128 scopus 로고    scopus 로고
    • Outcome results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial (FACET) in patients with hypertension and NIDDM
    • Tatti, P., Pahor, M., Byington, R. P., Di Mauro, P., Guarisco, R., Strollo, G., et al. (1998). Outcome results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial (FACET) in patients with hypertension and NIDDM. Diabetes Care, 21(4), 597-603.
    • (1998) Diabetes Care , vol.21 , Issue.4 , pp. 597-603
    • Tatti, P.1    Pahor, M.2    Byington, R.P.3    Di Mauro, P.4    Guarisco, R.5    Strollo, G.6
  • 69
    • 9744281234 scopus 로고    scopus 로고
    • Combination drug treatment of hypertension: Have we come full circle?
    • Taylor, A. A. (2004). Combination drug treatment of hypertension: Have we come full circle? Current Cardiology Reports, 6(6), 421-426.
    • (2004) Current Cardiology Reports , vol.6 , Issue.6 , pp. 421-426
    • Taylor, A.A.1
  • 72
    • 0242654867 scopus 로고    scopus 로고
    • Effects of different blood-pressure-lowering regimens on major cardiovascular events: Results of prospectively-designed overviews of randomised trials
    • Turnbull, F. (2003). Effects of different blood-pressure-lowering regimens on major cardiovascular events: Results of prospectively-designed overviews of randomised trials. Lancet, 362(9395), 1527-1535.
    • (2003) Lancet , vol.362 , Issue.9395 , pp. 1527-1535
    • Turnbull, F.1
  • 73
    • 33745004785 scopus 로고    scopus 로고
    • Biomarkers of cardiovascular disease: Molecular basis and practical considerations
    • Vasan, R. S. (2006). Biomarkers of cardiovascular disease: Molecular basis and practical considerations. Circulation, 113(19), 2335-2362.
    • (2006) Circulation , vol.113 , Issue.19 , pp. 2335-2362
    • Vasan, R.S.1
  • 75
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
    • The Heart Outcomes Prevention Evaluation Study Investigators.
    • Yusuf, S., Sleight, P., Pogue, J., Bosch, J., Davies, R., & Dagenais, G.; The Heart Outcomes Prevention Evaluation Study Investigators. (2000). Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. New England Journal of Medicine, 342(3), 145-153.
    • (2000) New England Journal of Medicine , vol.342 , Issue.3 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 77
    • 33748147006 scopus 로고    scopus 로고
    • Thiazide diuretics, potassium, and the development of diabetes: A quantitative review
    • Zillich, A. J., Garg, J., Basu, S., Bakris, G. L., & Carter, B. L. (2006). Thiazide diuretics, potassium, and the development of diabetes: A quantitative review. Hypertension, 48(2), 219-224.
    • (2006) Hypertension , vol.48 , Issue.2 , pp. 219-224
    • Zillich, A.J.1    Garg, J.2    Basu, S.3    Bakris, G.L.4    Carter, B.L.5


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