The Felodipine Event Reduction (FEVER) Study: A randomized long-term placebo-controlled trial in Chinese hypertensive patients

Journal of Hypertension

Volumn 23, Issue 12, 2005, Pages 2157-2172

  Liu, Lisheng ^a,b   Zhang, Yuqing ^a   Liu, Guozhang ^a   Li, Wei ^a   Zhang, Xuezhong ^b   Zanchetti, Alberto ^c  

^a FUWAI HOSPITAL   (China)

^b Beijing Hypertension League Institute   (China)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Calcium antagonist; Cardiovascular mortality; Hypertension; Stroke

Indexed keywords

CALCIUM ANTAGONIST; DIURETIC AGENT; FELODIPINE; HYDROCHLOROTHIAZIDE; PLACEBO;

ADD ON THERAPY; ADULT; AGED; ANKLE EDEMA; ANTIHYPERTENSIVE THERAPY; ARTICLE; CANCER; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAUSE OF DEATH; CHINESE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; DIZZINESS; DRUG TOLERABILITY; FATIGUE; FEMALE; FLUSHING; FOLLOW UP; HEART FAILURE; HEART INFARCTION; HUMAN; HYPERTENSION; INTERMETHOD COMPARISON; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; STROKE; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME;

EID: 27944473983     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.hjh.0000194120.42722.ac     Document Type: Article

References (33)

1. Wang L. 2002 National nutrition and health survey: report I [in Chinese]. General Report. Beijing: People's Medical Publishing House; 2005.
2. Kerney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005; 365:217-223.
3. Annals of Health of China Committee. 1999 annals of health of China [in Chinese]. Beijing, China: People's Health Press; 2000.
4. Asia Pacific Cohort Studies Collaboration. Blood pressure and cardiovascular disease in the Asia Pacific Region. J Hypertens 2003; 21:707-716.
5. Gong L, Zhang W, Zhu Y, Zhu J, Kong D, Page V, et al. Shanghai trial of nifedipine in the elderly (STONE). J Hypertens 1996; 14:1237-1245.
6. Liu L, Wang JG, Gong. Liu G, Staessen JA. Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension (Syst-China). J Hypertens 1998; 16:1823-1829.
7. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289:2560-2572.
8. Guidelines Committee 2003. European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21:1011-1059.
9. World Health Organization-International Society of Hypertension, Writing Group. World Health Organization-International Society of Hypertension statement on management of hypertension. J Hypertens 2003; 21:1983-1992.
10. Chinese Hypertension Guidelines Committee. Chinese Hypertensiom Guidelines. Chin J Hypertens 2004; 12:487-489.
11. The Heart Outcomes Prevention Evaluation Study Investigators. Effects of angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med 2000; 342:145-153.
12. PROGRESS Collaboration Study Group. Randomised trial of perindopril based blood pressure-lowering regimen among 6108 individuals with previous stroke or transient ischaemic attack. Lancet 2001; 358:1033-1041.
13. Lithell H, Hansson L, Skogg I, Elmfeldt D, Hofman A, Olofsson B, et al., for the SCOPE Study Group. The Study on Cognition and Prognosis in the Elderly (SCOPE). Principal results of a randomised double-blind intervention trial. J Hypertens 2003; 21:875-886.
14. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major cardiovascular events in hypertensive patients randomised to doxazosin vs chlorthalidone: the Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT). JAMA 2000; 283:1967-1975.
15. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomised to angiotensin-converting enzyme inhibitor or calcium channel blockers vs diuretic: The Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288:2981-2997.
16. Hansson L, Zanchetti A, Carruthers SG, Dahlöf B, Elmfeldt D, Julius S, et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet 1998; 351:1755-1762.
17. Zanchetti A, Hansson L, Clement D, Elmfeldt D, Julius S, Rosenthal T, et al., on behalf of the HOT Study Group. Benefits and risks of more intensive blood pressure lowering in hypertensive patients of the HOT Study with different risk profiles: does a J-shaped curve exist in smokers? J Hypertens 2003; 21:797-804.
18. Pepine CJ, Handberg EM, Cooper-De Hoff RM, Marks RG, Kowey P, Messerli FH, et al. A calcium antagonist versus a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial. JAMA 2003; 290:2805-2819.
19. Julius S, Kjeldsen SE, Weber M, Brunner HR, Ekman S, Hansson L, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine; the VALUE randomised trial. Lancet 2004; 363:2022-2031.
20. The European trial on reduction of cardiac events with perindopril in stable coronary artery disease investigators. Efficacy of perindropil in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003; 362:782-788.
21. Lubsen J, Wagener G, Kirwan B-A, de Brouwer S, Poole-Wilson A. Effects of long-acting nifedipine on mortality and cardiovascular morbidity in patients with symptomatic stable angina and hypertension: the ACTION trial. J Hypertens 2005; 23:641-648.
22. PATS Collaboration Group. Post-stroke antihyperytensive treatment study: a preliminary result. Chinese Med J 1995; 108:710-717.
23. Staessen JA, Fagard R, Thijs L, Celis H, Arabidze GG, Birkenhäger WH, et al., for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 1997; 350:757-764.
24. Dahlöf B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, et al. Cardiovascular morbidity and mortality in the Losartan Intervention Endpoint reduction in hypertension study. (LIFE): a randomised trial against atenolol. Lancet 2002; 359:995-1003.
25. Brown MJ, Palmer CR, Castaigne A, de Leeuw PW, Mancia G, Rosenthal T, Ruilope LM. Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). Lancet 2000; 356:366-372.
26. Black HR, Elliot WJ, Grandist G, Grambsch P, Lucente T, White WB, et al., for the CONVINCE Research Group. Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular Endpoints (CONVINCE) trial. JAMA 2003; 289:2073-2082.
27. Zanchetti A. Calcium channel blockers for hypertension. In: Black H, Elliot W, editors. Clinical hypertension. A companion of Braunwald's heart disease, Chapter 21. Philadelphia: Elsevier; 2005. In press.
28. Wassertheil-Smoller S, Psaty B, Greenland P, Oberman A, Kotchen T, Mouton C, et al. Association between cardiovascular outcomes and antihypertensive drug treatment in older women. JAMA 2004; 292:2849-2859.
29. Psaty B, Heckbert S, Koepsell T, Siscovick DS, Raghunathan TE, Weiss NS, et al. The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA 1995; 274:620-625.
30. Pahor M, Guralnik J, Ferrucci L, Corti MC, Salive ME, Cerhan JR, et al. Calcium channel blockade and incidence of cancer in aged populations. Lancet 1996; 348:493-497.
31. Pahor M, Guralnik J, Corti M, Foley DJ, Carbonin P, Havlik RJ. Long-term survival and use of antihypertensive medications in older persons. J Am Geriatr Soc 1995; 43:1191-1197.
32. Blood Pressure Lowering Treatment Trialists' Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomized trials. Lancet 2003; 362:1527-1535.
33. Zanchetti A. Evidence-based medicine in hypertension: what type of evidence? J Hypertens 2005; 23:1113-1120.