T-cell synapse formation depends on antigen recognition but not CD3 interaction: Studies with TCR:ζ, a candidate transgene for TCR gene therapy

European Journal of Immunology

Volumn 41, Issue 5, 2011, Pages 1288-1297

  Roszik, János ^a   Sebestyén, Zsolt ^b   Govers, Coen ^b   Guri, Yakir ^a   Szöor, Árpád ^a   Pályi Krekk, Zsuzsanna ^a   Vereb, György ^a   Nagy, Peter ^a   Szöllosi, János ^a   Debets, Reno ^b  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Adoptive T cell therapy; CD3; Fluorescence resonance energy transfer; Immune synapse; TCR:

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR ZETA; UNCLASSIFIED DRUG;

ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; CD3+ T LYMPHOCYTE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION; GENE INTERACTION; GENE THERAPY; GENETIC ENGINEERING; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; LEUKEMIA CELL LINE; LIPID RAFT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; T LYMPHOCYTE; TRANSGENE;

ADOPTIVE TRANSFER; ANTIGENS, CD28; ANTIGENS, CD3; ANTIGENS, CD45; ANTIGENS, CD8; FLOW CYTOMETRY; GENE THERAPY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNITY, CELLULAR; IMMUNOLOGICAL SYNAPSES; JURKAT CELLS; MEMBRANE MICRODOMAINS; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; TRANSGENES;

EID: 79955131030     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200940233     Document Type: Article

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