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Volumn 138, Issue 7, 2011, Pages 1297-1308

The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis

Author keywords

Basement membrane; Cardiogenesis; Epicardium; Flrt proteins; Leucine rich repeats; Mouse

Indexed keywords

FIBRONECTIN; LEUCINE; MEMBRANE PROTEIN; PROTEIN FLRT2; PROTEIN FLRT3; UNCLASSIFIED DRUG;

EID: 79955126801     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.059386     Document Type: Article
Times cited : (44)

References (57)
  • 2
    • 33745912405 scopus 로고    scopus 로고
    • A time-and cost-efficient system for high-level protein production in mammalian cells
    • Aricescu, A. R., Lu, W. and Jones, E. Y. (2006b). A time-and cost-efficient system for high-level protein production in mammalian cells. Acta Crystallogr. D Biol. Crystallogr. 62, 1243-1250.
    • (2006) Acta Crystallogr. D Biol. Crystallogr. , vol.62 , pp. 1243-1250
    • Aricescu, A.R.1    Lu, W.2    Jones, E.Y.3
  • 3
    • 0027054125 scopus 로고
    • The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo
    • Armstrong, J. F., Pritchard-Jones, K., Bickmore, W. A., Hastie, N. D. and Bard, J. B. (1993). The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo. Mech. Dev. 40, 85-97.
    • (1993) Mech. Dev. , vol.40 , pp. 85-97
    • Armstrong, J.F.1    Pritchard-Jones, K.2    Bickmore, W.A.3    Hastie, N.D.4    Bard, J.B.5
  • 4
    • 39749130550 scopus 로고    scopus 로고
    • Primary and immortalized mouse epicardial cells undergo differentiation in response to TGFbeta
    • Austin, A. F., Compton, L. A., Love, J. D., Brown, C. B. and Barnett, J. V. (2008). Primary and immortalized mouse epicardial cells undergo differentiation in response to TGFbeta. Dev. Dyn. 237, 366-376.
    • (2008) Dev. Dyn. , vol.237 , pp. 366-376
    • Austin, A.F.1    Compton, L.A.2    Love, J.D.3    Brown, C.B.4    Barnett, J.V.5
  • 6
    • 1342310738 scopus 로고    scopus 로고
    • The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling
    • Bottcher, R. T., Pollet, N., Delius, H. and Niehrs, C. (2004). The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling. Nat. Cell Biol. 6, 38-44.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 38-44
    • Bottcher, R.T.1    Pollet, N.2    Delius, H.3    Niehrs, C.4
  • 7
    • 33644680809 scopus 로고    scopus 로고
    • Building the mammalian heart from two sources of myocardial cells
    • Buckingham, M., Meilhac, S. and Zaffran, S. (2005). Building the mammalian heart from two sources of myocardial cells. Nat. Rev. Genet. 6, 826-835.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 826-835
    • Buckingham, M.1    Meilhac, S.2    Zaffran, S.3
  • 9
    • 0034254981 scopus 로고    scopus 로고
    • Tbx12, a novel T-box gene, is expressed during early stages of heart and retinal development
    • Carson, C. T., Kinzler, E. R. and Parr, B. A. (2000). Tbx12, a novel T-box gene, is expressed during early stages of heart and retinal development. Mech. Dev. 96, 137-140.
    • (2000) Mech. Dev. , vol.96 , pp. 137-140
    • Carson, C.T.1    Kinzler, E.R.2    Parr, B.A.3
  • 10
    • 0036392163 scopus 로고    scopus 로고
    • Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor
    • Chen, T. H., Chang, T. C., Kang, J. O., Choudhary, B., Makita, T., Tran, C. M., Burch, J. B., Eid, H. and Sucov, H. M. (2002). Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor. Dev. Biol. 250, 198-207.
    • (2002) Dev. Biol. , vol.250 , pp. 198-207
    • Chen, T.H.1    Chang, T.C.2    Kang, J.O.3    Choudhary, B.4    Makita, T.5    Tran, C.M.6    Burch, J.B.7    Eid, H.8    Sucov, H.M.9
  • 11
    • 77954048885 scopus 로고    scopus 로고
    • A protocadherincadherin-FLRT3 complex controls cell adhesion and morphogenesis
    • Chen, X., Koh, E., Yoder, M. and Gumbiner, B. M. (2009). A protocadherincadherin-FLRT3 complex controls cell adhesion and morphogenesis. PLoS One 4, e8411.
    • (2009) PLoS One , vol.4
    • Chen, X.1    Koh, E.2    Yoder, M.3    Gumbiner, B.M.4
  • 12
    • 11844271440 scopus 로고    scopus 로고
    • Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile
    • Dunn, N. R., Koonce, C. H., Anderson, D. C., Islam, A., Bikoff, E. K. and Robertson, E. J. (2005). Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. Genes Dev. 19, 152-163.
    • (2005) Genes Dev. , vol.19 , pp. 152-163
    • Dunn, N.R.1    Koonce, C.H.2    Anderson, D.C.3    Islam, A.4    Bikoff, E.K.5    Robertson, E.J.6
  • 14
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong, G. H., Rossant, J., Gertsenstein, M. and Breitman, M. L. (1995). Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376, 66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 15
    • 33748042282 scopus 로고    scopus 로고
    • Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development
    • Haines, B. P., Wheldon, L. M., Summerbell, D., Heath, J. K. and Rigby, P. W. (2006). Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development. Dev. Biol. 297, 14-25.
    • (2006) Dev. Biol. , vol.297 , pp. 14-25
    • Haines, B.P.1    Wheldon, L.M.2    Summerbell, D.3    Heath, J.K.4    Rigby, P.W.5
  • 16
    • 33646127606 scopus 로고    scopus 로고
    • PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains
    • Hirose, T., Karasawa, M., Sugitani, Y., Fujisawa, M., Akimoto, K., Ohno, S. and Noda, T. (2006). PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. Development 133, 1389-1398.
    • (2006) Development , vol.133 , pp. 1389-1398
    • Hirose, T.1    Karasawa, M.2    Sugitani, Y.3    Fujisawa, M.4    Akimoto, K.5    Ohno, S.6    Noda, T.7
  • 17
    • 77955588202 scopus 로고    scopus 로고
    • BMP signals promote proepicardial protrusion necessary for recruitment of coronary vessel and epicardial progenitors to the heart
    • Ishii, Y., Garriock, R. J., Navetta, A. M., Coughlin, L. E. and Mikawa, T. (2010). BMP signals promote proepicardial protrusion necessary for recruitment of coronary vessel and epicardial progenitors to the heart. Dev. Cell 19, 307-316.
    • (2010) Dev. Cell , vol.19 , pp. 307-316
    • Ishii, Y.1    Garriock, R.J.2    Navetta, A.M.3    Coughlin, L.E.4    Mikawa, T.5
  • 20
    • 33645768162 scopus 로고    scopus 로고
    • A role for fibronectinleucine-rich transmembrane cell-surface proteins in homotypic cell adhesion
    • Karaulanov, E. E., Bottcher, R. T. and Niehrs, C. (2006). A role for fibronectinleucine-rich transmembrane cell-surface proteins in homotypic cell adhesion. EMBO Rep. 7, 283-290.
    • (2006) EMBO Rep. , vol.7 , pp. 283-290
    • Karaulanov, E.E.1    Bottcher, R.T.2    Niehrs, C.3
  • 21
    • 0035692811 scopus 로고    scopus 로고
    • The leucine-rich repeat as a protein recognition motif
    • Kobe, B. and Kajava, A. V. (2001). The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol. 11, 725-732.
    • (2001) Curr. Opin. Struct. Biol. , vol.11 , pp. 725-732
    • Kobe, B.1    Kajava, A.V.2
  • 22
    • 4344682542 scopus 로고    scopus 로고
    • Dissecting MHC class II export, B cell maturation, and DM stability defects in invariant chain mutant mice
    • Koonce, C. H. and Bikoff, E. K. (2004). Dissecting MHC class II export, B cell maturation, and DM stability defects in invariant chain mutant mice. J. Immunol. 173, 3271-3280.
    • (2004) J. Immunol. , vol.173 , pp. 3271-3280
    • Koonce, C.H.1    Bikoff, E.K.2
  • 23
    • 0035211806 scopus 로고    scopus 로고
    • Cloning and expression analysis of the mouse T-box gene Tbx18
    • Kraus, F., Haenig, B. and Kispert, A. (2001). Cloning and expression analysis of the mouse T-box gene Tbx18. Mech. Dev. 100, 83-86.
    • (2001) Mech. Dev. , vol.100 , pp. 83-86
    • Kraus, F.1    Haenig, B.2    Kispert, A.3
  • 24
    • 0028952534 scopus 로고
    • Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice
    • Kwee, L., Baldwin, H. S., Shen, H. M., Stewart, C. L., Buck, C., Buck, C. A. and Labow, M. A. (1995). Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice. Development 121, 489-503.
    • (1995) Development , vol.121 , pp. 489-503
    • Kwee, L.1    Baldwin, H.S.2    Shen, H.M.3    Stewart, C.L.4    Buck, C.5    Buck, C.A.6    Labow, M.A.7
  • 25
    • 0343384235 scopus 로고    scopus 로고
    • Identification of FLRT1, FLRT2, and FLRT3: A novel family of transmembrane leucine-rich repeat proteins
    • Lacy, S. E., Bonnemann, C. G., Buzney, E. A. and Kunkel, L. M. (1999). Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins. Genomics 62, 417-426.
    • (1999) Genomics , vol.62 , pp. 417-426
    • Lacy, S.E.1    Bonnemann, C.G.2    Buzney, E.A.3    Kunkel, L.M.4
  • 26
    • 59849089050 scopus 로고    scopus 로고
    • Shared circuitry: Developmental signaling cascades regulate both embryonic and adult coronary vasculature
    • Lavine, K. J. and Ornitz, D. M. (2009). Shared circuitry: developmental signaling cascades regulate both embryonic and adult coronary vasculature. Circ. Res. 104, 159-169.
    • (2009) Circ. Res. , vol.104 , pp. 159-169
    • Lavine, K.J.1    Ornitz, D.M.2
  • 27
    • 11244306331 scopus 로고    scopus 로고
    • Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo
    • Lavine, K. J., Yu, K., White, A. C., Zhang, X., Smith, C., Partanen, J. and Ornitz, D. M. (2005). Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev. Cell 8, 85-95.
    • (2005) Dev. Cell , vol.8 , pp. 85-95
    • Lavine, K.J.1    Yu, K.2    White, A.C.3    Zhang, X.4    Smith, C.5    Partanen, J.6    Ornitz, D.M.7
  • 29
    • 0034956857 scopus 로고    scopus 로고
    • The origin, formation and developmental significance of the epicardium: A review
    • Manner, J., Perez-Pomares, J. M., Macias, D. and Munoz-Chapuli, R. (2001). The origin, formation and developmental significance of the epicardium: a review. Cells Tissues Organs 169, 89-103.
    • (2001) Cells Tissues Organs , vol.169 , pp. 89-103
    • Manner, J.1    Perez-Pomares, J.M.2    McIas, D.3    Munoz-Chapuli, R.4
  • 30
    • 43449113236 scopus 로고    scopus 로고
    • Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucinerich transmembrane protein FLRT3
    • Maretto, S., Müller, P. S., Aricescu, A. R., Cho, K. W., Bikoff, E. K. and Robertson, E. J. (2008). Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucinerich transmembrane protein FLRT3. Dev. Biol. 318, 184-193.
    • (2008) Dev. Biol. , vol.318 , pp. 184-193
    • Maretto, S.1    Müller, P.S.2    Aricescu, A.R.3    Cho, K.W.4    Bikoff, E.K.5    Robertson, E.J.6
  • 31
    • 41449094683 scopus 로고    scopus 로고
    • Lives of a heart cell: Tracing the origins of cardiac progenitors
    • Martin-Puig, S., Wang, Z. and Chien, K. R. (2008). Lives of a heart cell: tracing the origins of cardiac progenitors. Cell Stem Cell 2, 320-331.
    • (2008) Cell Stem Cell , vol.2 , pp. 320-331
    • Martin-Puig, S.1    Wang, Z.2    Chien, K.R.3
  • 33
    • 20744435127 scopus 로고    scopus 로고
    • Boundary formation in the Drosophila wing: Functional dissection of Capricious and Tartan
    • Milan, M., Perez, L. and Cohen, S. M. (2005). Boundary formation in the Drosophila wing: functional dissection of Capricious and Tartan. Dev. Dyn. 233, 804-810.
    • (2005) Dev. Dyn. , vol.233 , pp. 804-810
    • Milan, M.1    Perez, L.2    Cohen, S.M.3
  • 35
    • 0025884056 scopus 로고
    • Efficient selection for highexpression transfectants with a novel eukaryotic vector
    • Niwa, H., Yamamura, K. and Miyazaki, J. (1991). Efficient selection for highexpression transfectants with a novel eukaryotic vector. Gene 108, 193-199.
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 36
    • 34447532460 scopus 로고    scopus 로고
    • TGF-beta signaling-mediated morphogenesis: Modulation of cell adhesion via cadherin endocytosis
    • Ogata, S., Morokuma, J., Hayata, T., Kolle, G., Niehrs, C., Ueno, N. and Cho, K. W. (2007). TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev. 21, 1817-1831.
    • (2007) Genes Dev. , vol.21 , pp. 1817-1831
    • Ogata, S.1    Morokuma, J.2    Hayata, T.3    Kolle, G.4    Niehrs, C.5    Ueno, N.6    Cho, K.W.7
  • 37
    • 33749361499 scopus 로고    scopus 로고
    • Gene regulatory networks in the evolution and development of the heart
    • Olson, E. N. (2006). Gene regulatory networks in the evolution and development of the heart. Science 313, 1922-1927.
    • (2006) Science , vol.313 , pp. 1922-1927
    • Olson, E.N.1
  • 38
    • 0035890056 scopus 로고    scopus 로고
    • ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation
    • Ong, S. H., Dilworth, S., Hauck-Schmalenberger, I., Pawson, T. and Kiefer, F. (2001). ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation. EMBO J. 20, 6327-6336.
    • (2001) EMBO J. , vol.20 , pp. 6327-6336
    • Ong, S.H.1    Dilworth, S.2    Hauck-Schmalenberger, I.3    Pawson, T.4    Kiefer, F.5
  • 39
    • 77950237662 scopus 로고    scopus 로고
    • Coronary arteries form by developmental reprogramming of venous cells
    • Red-Horse, K., Ueno, H., Weissman, I. L. and Krasnow, M. A. (2010). Coronary arteries form by developmental reprogramming of venous cells. Nature 464, 549-553.
    • (2010) Nature , vol.464 , pp. 549-553
    • Red-Horse, K.1    Ueno, H.2    Weissman, I.L.3    Krasnow, M.A.4
  • 40
    • 70350020783 scopus 로고    scopus 로고
    • Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development
    • Rhee, D. Y., Zhao, X. Q., Francis, R. J., Huang, G. Y., Mably, J. D. and Lo, C. W. (2009). Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development. Development 136, 3185-3193.
    • (2009) Development , vol.136 , pp. 3185-3193
    • Rhee, D.Y.1    Zhao, X.Q.2    Francis, R.J.3    Huang, G.Y.4    Mably, J.D.5    Lo, C.W.6
  • 42
    • 0037182578 scopus 로고    scopus 로고
    • Dual functions of alpha4beta1 integrin in epicardial development: Initial migration and long-term attachment
    • Sengbusch, J. K., He, W., Pinco, K. A. and Yang, J. T. (2002). Dual functions of alpha4beta1 integrin in epicardial development: initial migration and long-term attachment. J. Cell Biol. 157, 873-882.
    • (2002) J. Cell Biol. , vol.157 , pp. 873-882
    • Sengbusch, J.K.1    He, W.2    Pinco, K.A.3    Yang, J.T.4
  • 44
    • 33846289977 scopus 로고    scopus 로고
    • The expression of Flrt3 during chick limb development
    • Smith, T. G. and Tickle, C. (2006). The expression of Flrt3 during chick limb development. Int. J. Dev. Biol. 50, 701-704.
    • (2006) Int. J. Dev. Biol. , vol.50 , pp. 701-704
    • Smith, T.G.1    Tickle, C.2
  • 45
    • 76249121966 scopus 로고    scopus 로고
    • A cell surface interaction network of neural leucine-rich repeat receptors
    • Sollner, C. and Wright, G. J. (2009). A cell surface interaction network of neural leucine-rich repeat receptors. Genome Biol. 10, R99.
    • (2009) Genome Biol. , vol.10
    • Sollner, C.1    Wright, G.J.2
  • 47
    • 0034648772 scopus 로고    scopus 로고
    • A genetic blueprint for cardiac development
    • Srivastava, D. and Olson, E. N. (2000). A genetic blueprint for cardiac development. Nature 407, 221-226.
    • (2000) Nature , vol.407 , pp. 221-226
    • Srivastava, D.1    Olson, E.N.2
  • 48
    • 21044446280 scopus 로고    scopus 로고
    • Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation
    • Stennard, F. A., Costa, M. W., Lai, D., Biben, C., Furtado, M. B., Solloway, M. J., McCulley, D. J., Leimena, C., Preis, J. I., Dunwoodie, S. L. et al. (2005). Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development 132, 2451-2462.
    • (2005) Development , vol.132 , pp. 2451-2462
    • Stennard, F.A.1    Costa, M.W.2    Lai, D.3    Biben, C.4    Furtado, M.B.5    Solloway, M.J.6    McCulley, D.J.7    Leimena, C.8    Preis, J.I.9    Dunwoodie, S.L.10
  • 49
    • 0031897379 scopus 로고    scopus 로고
    • Molecular insights into cardiac development
    • Sucov, H. M. (1998). Molecular insights into cardiac development. Annu. Rev. Physiol. 60, 287-308.
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 287-308
    • Sucov, H.M.1
  • 50
    • 77955334500 scopus 로고    scopus 로고
    • How to make a heart: The origin and regulation of cardiac progenitor cells
    • Vincent, S. D. and Buckingham, M. E. (2010). How to make a heart: the origin and regulation of cardiac progenitor cells. Curr. Top. Dev. Biol. 90, 2-41.
    • (2010) Curr. Top. Dev. Biol. , vol.90 , pp. 2-41
    • Vincent, S.D.1    Buckingham, M.E.2
  • 51
    • 5444220114 scopus 로고    scopus 로고
    • Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements
    • Vincent, S. D., Norris, D. P., Le Good, J. A., Constam, D. B. and Robertson, E. J. (2004). Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements. Mech. Dev. 121, 1403-1415.
    • (2004) Mech. Dev. , vol.121 , pp. 1403-1415
    • Vincent, S.D.1    Norris, D.P.2    le Good, J.A.3    Constam, D.B.4    Robertson, E.J.5
  • 52
    • 4344565788 scopus 로고    scopus 로고
    • GATA4 is essential for formation of the proepicardium and regulates cardiogenesis
    • Watt, A. J., Battle, M. A., Li, J. and Duncan, S. A. (2004). GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc. Natl. Acad. Sci. USA 101, 12573-12578.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 12573-12578
    • Watt, A.J.1    Battle, M.A.2    Li, J.3    Duncan, S.A.4
  • 53
    • 77956407054 scopus 로고    scopus 로고
    • Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling
    • Wheldon, L. M., Haines, B. P., Rajappa, R., Mason, I., Rigby, P. W. and Heath, J. K. (2010). Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling. PLoS One 5, e10264.
    • (2010) PLoS One , vol.5
    • Wheldon, L.M.1    Haines, B.P.2    Rajappa, R.3    Mason, I.4    Rigby, P.W.5    Heath, J.K.6
  • 54
    • 33947538193 scopus 로고    scopus 로고
    • Epicardium-derived cells in cardiogenesis and cardiac regeneration
    • Winter, E. M. and Gittenberger-de Groot, A. C. (2007). Epicardium-derived cells in cardiogenesis and cardiac regeneration. Cell. Mol. Life Sci. 64, 692-703.
    • (2007) Cell. Mol. Life Sci. , vol.64 , pp. 692-703
    • Winter, E.M.1    Gittenberger-de Groot, A.C.2
  • 55
    • 0028955748 scopus 로고
    • Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development
    • Yang, J. T., Rayburn, H. and Hynes, R. O. (1995). Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. Development 121, 549-560.
    • (1995) Development , vol.121 , pp. 549-560
    • Yang, J.T.1    Rayburn, H.2    Hynes, R.O.3


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