Modulation of oxidative stress responses in the human retinal pigment epithelium following treatment with vitamin C

Journal of Cellular Physiology

Volumn 226, Issue 8, 2011, Pages 2025-2032

  Yin, Jinggang ^a   Thomas, Fridtjof ^a   Lang, John C ^b   Chaum, Edward ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b ALCON RESEARCH LTD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; HYDROGEN PEROXIDE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION;

ACTIVATING TRANSCRIPTION FACTOR 3; ANTIOXIDANTS; ASCORBIC ACID; BIOLOGICAL MARKERS; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-FOS; RETINAL PIGMENT EPITHELIUM; TRANSCRIPTION FACTOR AP-1;

EID: 79955111085     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22532     Document Type: Article

References (41)

1. Abate C, Patel L, Rauscher FJ III, Curran T. 1990. Redox regulation of fos and jun DNA-binding activity in vitro. Science 249: 1157-1161.
2. Amstad PA, Krupitza G, Cerutti PA. 1992. Mechanism of c-fos induction by active oxygen. Cancer Res 52: 3952-3960.
3. Age-Related Eye Disease Study Research Group. 2001. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS Report No. 8. Arch Ophthalmol 119: 1417-1436.
4. Arkan MC, Leonarduzzi G, Biasi F, Başaǧa H, Poli G. 2001. Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage. Free Radic Biol Med 31: 374-382.
5. Biondi C, Pavan B, Dalpiaz A, Medici S, Lunghi L, Vesce F. 2007. Expression and characterization of vitamin C transporter in the human trophoblast cell line HTR-8/SV neo: Effect of steroids, flavonoids and NSAIDs. Mol Hum Reprod 13: 77-83.
6. Caprile T, Salazar K, Astuya A, Cisternas P, Silva-Alvarez C, Montecinos H, Millán C, de Los Angeles García M, Nualart F. 2009. The Na+-dependent L-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids. J Neurochem 108: 563-577.
7. Catani MV, Rossi A, Costanzo A, Sabatini S, Levrero M, Melino G, Avigliano L. 2001. Induction of gene expression via activator protein-1 in the ascorbate protection against UV-induced damage. Biochem J 356: 77-85.
8. Catani MV, Savini I, Rossi A, Melino G, Avigliano L. 2005. Biological role of vitamin C in keratinocytes. Nutr Rev 63: 81-90.
9. Cavigelli M, Li WW, Lin A, Su B, Yoshioka K, Karin M. 1996. The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. EMBO J 15: 6269-6279.
10. Chang HJ, Park JS, Lee EK, Kim MH, Baek MK, Kim HR, Jeong HG, Choi SY, Jung YD. 2009. Ascorbic acid suppresses the 2, 3, 7, 8-tetrachloridibenxo-p-dioxin(TCDD)-induced CYP1A1 expression in human HepG2 cells. Toxicol In Vitro 23: 622-626.
11. Chaum E, Yin J, Yang H, Thomas F, Lang JC. 2009. Quantitative AP-1 gene regulation by oxidative stress in the human retinal pigment epithelium. J Cell Biochem 108: 1280-1291.
12. Chinenov Y, Kerppola TK. 2001. Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20: 2438-2452.
13. Chiu R, Angel P, Karin M. 1989. Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun. Cell 59: 979-986.
14. Devary Y, Gottlieb RA, Lau LF, Karin M. 1991. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell Biol 11: 2804-2811.
15. Duarte TL, Lunec J. 2005. Review: When is an antioxidant not an antioxidant? A review of novel actions and reactions of vitamin C. Free Radic Res 39: 671-686.
16. Esposito F, Cuccovillo F, Morra F, Russo T, Cimino F. 1995. DNA binding activity of the glucocorticoid receptor is sensitive to redox changes in intact cells. Biochim Biophys Acta 1260: 308-314.
17. Geller SF, Stone J. 2003. Quantitative PCR analysis of FosB mRNA expression after short duration oxygen and light stress. Adv Exp Med Biol 533: 249-257.
18. Giddabasappa A, Bauler M, Yepuru M, Chaum E, Dalton JT, Eswaraka J. 2010. 17-β estradiol protects ARPE-19 cells from oxidative stress through estrogen receptor-β. Invest Ophthalmol Vis Sci 51: 5278-5287.
19. Gonzales M, Bowden GT. 2002. Ultraviolet B (UVB) induction of the c-fos promoter is mediated by phospho-cAMP response element binding protein (CREB) binding to CRE and c-fos activator protein 1 site (FAP1) cis elements. Gene 293: 169-179.
20. Halliwell B, Hu ML, Louie S, Duvall TR, Tarkington BK, Motchnik P, Cross CE. 1992. Interaction of nitrogen dioxide with human plasma. Antioxidant depletion and oxidative damage. FEBS Lett 313: 62-66.
21. Harman D. 2006. Alzheimer's disease pathogenesis: Role of aging. Ann NY Acad Sci 1067: 454-460.
22. Holm S. 1979. A simple sequentially rejective multiple test procedure. Scan J Stat 6: 65-70.
23. Hothorn T, Bretz F, Westfall P. Simultaneous inference in general parametric models. Biom J 2008; 50: 346-363.
24. Karin M. 1995. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270: 16483-16486.
25. Kutner MH, Nachtsheim CJ, Neter J, Li W. 2005. Applied linear statistical models, 5th edition. Boston: McGraw-Hill/Irvin.
26. Lallemand D, Spyrou G, Yaniv M, Pfarr CM. 2006. Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts. Oncogene 14: 819-830.
27. Loke WM, Proudfoot JM, McKinley AJ, Croft KD. 2006. Augmentation of monocyte intracellular ascorbate in vitro protects cells from oxidative damage and inflammatory responses. Biochem Biophys Res Commun 345: 1039-1043.
28. Lu D, Chen J, Hai T. 2007. The regulation of ATF3 gene expression by mitogen-activated protein kinases. Biochem J 401: 559-567.
29. Manfredini S, Vertuani S, Pavan B, Vitali F, Scaglianti M, Bortolotti F, Biondi C, Scatturin A, Prasad P, Dalpiaz A. 2004. Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules. Bioorg Med Chem 12: 5453-5463.
30. Mitchell PJ, Tjian R. 1989. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245: 371-378.
31. Morgan JI, Curran T. 1991. Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun. Annu Rev Neurosci 14: 421-451.
32. Morris BJ. 1995. Stimulation of immediate early gene expression in striatal neurons by nitric oxide. J Biol Chem 270: 24740-24744.
33. Olson ER, Melton T, Dickinson SE, Dong Z, Alberts DS, Bowden GT. 2010. Quercetin potentiates UVB-induced c-Fos expression: Implications for its use as a chemopreventive agent. Cancer Prev Res 3: 876-884.
34. Portugal CC, Miya VS, Calaza Kda C, Santos RA, Paes-de-Carvalho R. 2009. Glutamate receptors modulate sodium-dependent and calcium-independent vitamin C bidirectional transport in cultured Avian retinal cells. J Neurochem 108: 507-520.
35. Reddy SP, Mossman BT. 2002. Role and regulation of activator protein-1 in toxicant-induced responses of the lung. Am J Physiol Lung Cell Mol Physiol 283: L1161-L1178.
36. Shaulian E, Karin M. 2001. AP-1 in cell proliferation and survival. Oncogene 20: 2390-2400.
37. Takeda M, Kato H, Takamiya A, Yoshida A, Kiyama H. 2000. Injury-specific expression of activating transcription factor-3 in retinal ganglion cells and its colocalized expression with phosphorylated c-Jun. Invest Ophthalmol Vis Sci 41: 2412-2421.
38. Wang Y, Mackenzie B, Tsukaguchi H, Weremowicz S, Morton CC, Hediger MA. 2000. Human vitamin C (L-ascorbic acid) transporter SVCT1. Biochem Biophys Res Commun 267: 488-494.
39. Winkler BS, Boulton ME, Gottsch JD, Sternberg P. 1999. Oxidative damage and age-related macular degeneration. Mol Vis 5: 32-59.
40. Xanthoudakis S, Curran T. 1992. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J 11: 653-665.
41. Yang H, Yang X, Lang JC, Chaum E. 2006. Tissue culture methods can strongly induce immediate early gene expression in retinal pigment epithelial cells. J Cell Biochem 98: 1560-1569.