Ascorbic acid suppresses the 2,3,7,8-tetrachloridibenxo-p-dioxin (TCDD)-induced CYP1A1 expression in human HepG2 cells

Toxicology in Vitro

Volumn 23, Issue 4, 2009, Pages 622-626

  Chang, Hee J ^a   Park, Jung S ^a   Lee, Eun K ^b   Kim, Mi H ^a   Baek, Min K ^a   Kim, Hyeong R ^a   Jeong, Hye G ^c   Choi, Seok Y ^a   Jung, Young D ^a  

^a Chonnam National University Medical School   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Ascorbic acid; Cytochrome P4501A1; HepG2 cells; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ADENOSINE TRIPHOSPHATASE; AROMATIC HYDROCARBON RECEPTOR; ASCORBIC ACID; CYTOCHROME P450 1A1; ETHOXYRESORUFIN DEETHYLASE; LUCIFERASE; MESSENGER RNA;

ARTICLE; CATALYSIS; CELL CULTURE; CELL NUCLEUS; CELL STRAIN HEPG2; DRUG EFFECT; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE INDUCTION; GENE TRANSLOCATION; GENOTOXICITY; HUMAN; HUMAN CELL; INHIBITION KINETICS; METABOLITE; MUTAGENESIS; PROMOTER REGION; PROTEIN EXPRESSION; TRANSIENT TRANSFECTION;

ANTIGENS, CD; APYRASE; ASCORBIC ACID; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; HUMANS; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

EID: 67349085177     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.02.008     Document Type: Article

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