메뉴 건너뛰기




Volumn 98, Issue 3, 2011, Pages 239-246

DNA repair and tumour radiosensitivity: Focus on ATM gene;Réparation cellulaire et radiosensibilité tumorale: Focus sur le gène ATM

Author keywords

ATM; DNA repair; p53; Radiosensitivity

Indexed keywords

ATM PROTEIN; PROTEIN P53;

EID: 79955098395     PISSN: 00074551     EISSN: 17696917     Source Type: Journal    
DOI: 10.1684/bdc.2011.1324     Document Type: Review
Times cited : (11)

References (47)
  • 1
    • 0038626211 scopus 로고    scopus 로고
    • Tumor response to radiotherapy regulated by endothelial cell apoptosis
    • Garcia-Barros M, Paris F, Cordon-Cardo C, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003 : 300.
    • (2003) Science , pp. 300
    • Garcia-Barros, M.1    Paris, F.2    Cordon-Cardo, C.3
  • 2
    • 0025163422 scopus 로고
    • Response of human squamous cell carcinoma xenografts of different sizes to irradiation: Relationship of clonogenic cells, cellular radiation sensitivity in vivo, and tumor rescuing units
    • Baumann M, duBois W, Suit H. Response of human squamous cell carcinoma xenografts of different sizes to irradiation: relationship of clonogenic cells, cellular radiation sensitivity in vivo, and tumor rescuing units. Radiat Res 1990 ; 123 : 325-30. (Pubitemid 20327905)
    • (1990) Radiation Research , vol.123 , Issue.3 , pp. 325-330
    • Baumann, M.1    DuBois, W.2    Suit, H.D.3
  • 3
    • 0022363207 scopus 로고
    • Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves
    • Fertil B, Malaise E. Intrinsic radiosensitivity of human cells is correlated with radioresponsiveness of human tumors. Int J Radiat Oncol Biol Phys 1985 ; 11 : 1699-707. (Pubitemid 15233633)
    • (1985) International Journal of Radiation Oncology Biology Physics , vol.11 , Issue.9 , pp. 1699-1707
    • Fertil, B.1    Malaise, E.P.2
  • 4
    • 0023695721 scopus 로고
    • Radio-resistant tumor cells are present in head and neck carcinomas that reccur after radiotherapy
    • Weichselbaum RR, Beckett MA, Schwartz JL, et al. Radio-resistant tumor cells are present in head and neck carcinomas that reccur after radiotherapy. Int J Radiat Oncol Biol 1988 ; 15 : 575-9.
    • (1988) Int J Radiat Oncol Biol , vol.15 , pp. 575-579
    • Weichselbaum, R.R.1    Beckett, M.A.2    Schwartz, J.L.3
  • 5
    • 0024388373 scopus 로고
    • Evaluation of surviving fraction at 2 Gy as a potential prognostic factor for the radiotherapy of carcinoma of the cervix
    • West CM, Davidson SE, Hunter RD. Evaluation of surviving fraction at 2 Gy as a potential prognostic factor for the radiotherapy of carcinoma of the cervix. Int J Radiat Biol 1989 ; 56 : 761-5. (Pubitemid 20002025)
    • (1989) International Journal of Radiation Biology , vol.56 , Issue.5 , pp. 761-765
    • West, C.M.L.1    Davidson, S.E.2    Hunter, R.D.3
  • 7
    • 0026303274 scopus 로고
    • The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells
    • Iliakis G. The role of DNA double-strand breaks in ionizing radiation-induced killing of eukaryotics cells. Bioessays 1991 ; 13 : 641-8. (Pubitemid 21892586)
    • (1991) BioEssays , vol.13 , Issue.12 , pp. 641-648
    • Iliakis, G.1
  • 8
    • 79955094031 scopus 로고    scopus 로고
    • Effets cellulaires des rayonnements ionisants. Radiosensibilité, cycle cellulaire et mort cellulaire
    • Tubiana M, editor. Paris : Hermann
    • Favaudon V. Effets cellulaires des rayonnements ionisants. Radiosensibilité, cycle cellulaire et mort cellulaire. In : Tubiana M, editor. Radiobiologie. Paris : Hermann, 2007.
    • (2007) Radiobiologie
    • Favaudon, V.1
  • 9
    • 34249048068 scopus 로고    scopus 로고
    • Radiosensibilité intrinsèque et cassures double-brin de l'ADN dans les cellules humaines
    • Joubert A, Foray N. Radiosensibilité intrinsèque et cassures double-brin de l'ADN dans les cellules humaines. Cancer Radioth 2007 ; 11 : 129-42.
    • (2007) Cancer Radioth , vol.11 , pp. 129-142
    • Joubert, A.1    Foray, N.2
  • 10
    • 0141757494 scopus 로고    scopus 로고
    • Regulation and mechanisms of mammalian double-strand break repair
    • DOI 10.1038/sj.onc.1206679
    • Valerie K, Povirk L. Regulation and mechanisms of mammalian double-strand break reapir. Oncogene 2003 ; 22 : 5792-812. (Pubitemid 37176701)
    • (2003) Oncogene , vol.22 , Issue.37 REV. ISS. 3 , pp. 5792-5812
    • Valerie, K.1    Povirk, L.F.2
  • 12
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to PI-3 kinase
    • Savitsky K, Bar-Shira A, Gilad S, et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 1995 ; 268 : 1749-53.
    • (1995) Science , vol.268 , pp. 1749-1753
    • Savitsky, K.1    Bar-Shira, A.2    Gilad, S.3
  • 13
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • DOI 10.1038/nature01368
    • Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003 ; 421 : 499-506. (Pubitemid 36168436)
    • (2003) Nature , vol.421 , Issue.6922 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 15
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • Mahaney BL, Meek K, Lees-Miller SP. Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem J 2009 ; 417 : 639-50.
    • (2009) Biochem J , vol.417 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 16
    • 0141740426 scopus 로고    scopus 로고
    • Focusing on foci: H2AX and the recruitment of DNA-damage response factors
    • Fernandez-Capetillo O, Celeste A, Nussenzweig A. Focusing on foci: H2AX and the recruitment of DNA-damage response factors. Cell Cycle 2003 ; 2 : 426-7.
    • (2003) Cell Cycle , vol.2 , pp. 426-427
    • Fernandez-Capetillo, O.1    Celeste, A.2    Nussenzweig, A.3
  • 18
    • 29244434544 scopus 로고    scopus 로고
    • MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
    • DOI 10.1016/j.cell.2005.09.038, PII S0092867405011657
    • Stucki M, Clapperton JA, Mohammad D, et al. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 2005 ; 123 : 1213-26. (Pubitemid 41821780)
    • (2005) Cell , vol.123 , Issue.7 , pp. 1213-1226
    • Stucki, M.1    Clapperton, J.A.2    Mohammad, D.3    Yaffe, M.B.4    Smerdon, S.J.5    Jackson, S.P.6
  • 19
    • 48649100438 scopus 로고    scopus 로고
    • Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage
    • Chapman JR, Jackson SP. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage. EMBO Rep 2008 ; 9 : 795-801.
    • (2008) EMBO Rep , vol.9 , pp. 795-801
    • Chapman, J.R.1    Jackson, S.P.2
  • 21
    • 4944234150 scopus 로고    scopus 로고
    • Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines
    • DOI 10.1158/0008-5472.CAN-04-1433
    • Banath JP, Macphail SH, Olive PL. Radiation sensitivity. H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines. Cancer Res 2004 ; 64 : 7144-9. (Pubitemid 39331029)
    • (2004) Cancer Research , vol.64 , Issue.19 , pp. 7144-7149
    • Banath, J.P.1    MacPhail, S.H.2    Olive, P.L.3
  • 23
    • 66849138419 scopus 로고    scopus 로고
    • Solving the RIDDLE of 53BP1 recruitment to sites of damage
    • Stewart GS. Solving the RIDDLE of 53BP1 recruitment to sites of damage. Cell Cycle 2009 ; 8 : 1532-8.
    • (2009) Cell Cycle , vol.8 , pp. 1532-1538
    • Stewart, G.S.1
  • 24
    • 0016786321 scopus 로고
    • Ataxia telangiectasia: A human mutation with abnormal radiation sensitivity
    • Taylor AM, Harnden DG, Arlett CF, et al. Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity. Nature 1975 ; 258 : 427-9.
    • (1975) Nature , vol.258 , pp. 427-429
    • Taylor, A.M.1    Harnden, D.G.2    Arlett, C.F.3
  • 25
    • 3242876404 scopus 로고    scopus 로고
    • Ataxia-telangiectasia, an evolving phenotype
    • DOI 10.1016/j.dnarep.2004.04.010, PII S1568786404001417
    • Chun HH, Gatti RA. Ataxia-telangiectasia, an evolving phenotype. DNA Repair (Amst) 2004 ; 3 : 1187-96. (Pubitemid 38997962)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 1187-1196
    • Chun, H.H.1    Gatti, R.A.2
  • 26
    • 0033165608 scopus 로고    scopus 로고
    • La DNA-PK: Une enzyme-clé de la réparation des lésions radio-induites
    • Hennequin C, Giocanti N, Averbeck D, et al. La DNA-PK : une enzyme-clé de la réparation des lésions radio-induites. Cancer/ Radioth 1999 ; 3 : 289-95.
    • (1999) Cancer/ Radioth , vol.3 , pp. 289-295
    • Hennequin, C.1    Giocanti, N.2    Averbeck, D.3
  • 29
    • 0029145291 scopus 로고
    • A comparison of the radiosensitivity of lymphocytes from normal donors, cancer patients, individuals with ataxia-telangiectasia (AT) and AT heterozygotes
    • West CM, Elyan SA, Berry P, et al. A comparison of the radiosensitivity of lymphocytes from normal donors, cancer patients, individuals with ataxia-telangiectasia (AT) and AT heterozygotes. Int J Radiat Biol 1995 ; 68 : 197-203.
    • (1995) Int J Radiat Biol , vol.68 , pp. 197-203
    • West, C.M.1    Elyan, S.A.2    Berry, P.3
  • 31
    • 0035370172 scopus 로고    scopus 로고
    • ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture
    • DOI 10.1016/S0360-3016(01)01489-4, PII S0360301601014894
    • Tribius S, Pidel A, Casper D. ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture. Int J Radiat Oncol Biol Phys 2001 ; 50 : 511-23. (Pubitemid 32472281)
    • (2001) International Journal of Radiation Oncology Biology Physics , vol.50 , Issue.2 , pp. 511-523
    • Tribius, S.1    Pidel, A.2    Casper, D.3
  • 33
    • 46449117415 scopus 로고    scopus 로고
    • Risk of cancer by ATM missense mutations in the general population
    • Dombernowsky SL, Weischer M, Allin KH, et al. Risk of cancer by ATM missense mutations in the general population. J Clin Oncol 2008 ; 26 : 3057-62.
    • (2008) J Clin Oncol , vol.26 , pp. 3057-3062
    • Dombernowsky, S.L.1    Weischer, M.2    Allin, K.H.3
  • 34
    • 23844507598 scopus 로고    scopus 로고
    • The Ataxia-telangiectasia mutated gene and breast cancer: Gene expression profiles and sequence variants
    • DOI 10.1016/j.canlet.2004.12.001, PII S0304383504009644
    • Hall J. The Ataxia-telangiectasia mutated gene and breast cancer: gene expression profiles and sequence variants. Cancer Lett 2005 ; 227 : 105-14. (Pubitemid 41169924)
    • (2005) Cancer Letters , vol.227 , Issue.2 , pp. 105-114
    • Hall, J.1
  • 36
    • 33745211656 scopus 로고    scopus 로고
    • TGFbeta1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors
    • De Ruyck K, Van Eijkeren M, Claes K, et al. TGFbeta1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors. Int J Radiat Oncol Biol Phys 2006 ; 65 : 1240-8.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , pp. 1240-1248
    • De Ruyck, K.1    Van Eijkeren, M.2    Claes, K.3
  • 37
    • 67349231216 scopus 로고    scopus 로고
    • Adjuvant irradiation in breast cancer patients with ATM gene heterozygous mutations: Special focus on clinical efficacy/toxicity
    • Chargari C, Kirova YM, Even C, et al. Adjuvant irradiation in breast cancer patients with ATM gene heterozygous mutations: special focus on clinical efficacy/toxicity. Cancer Radiother 2009 ; 13 : 164-72.
    • (2009) Cancer Radiother , vol.13 , pp. 164-172
    • Chargari, C.1    Kirova, Y.M.2    Even, C.3
  • 39
    • 58149144774 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy
    • Azria D, Ozsahin M, Kramar A, et al. Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy. Clin Cancer Res 2008 ; 14 : 6284-8.
    • (2008) Clin Cancer Res , vol.14 , pp. 6284-6288
    • Azria, D.1    Ozsahin, M.2    Kramar, A.3
  • 40
    • 3242876403 scopus 로고    scopus 로고
    • Genetic biomarkers of therapeutic radiation sensitivity
    • DOI 10.1016/j.dnarep.2004.03.019, PII S1568786404000783
    • Fernet M, Hall J. Genetic biomarkers of therapeutic radiation sensitivity. DNA Repair (Amst) 2004 ; 3 : 1237-43. (Pubitemid 38997967)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 1237-1243
    • Fernet, M.1    Hall, J.2
  • 41
    • 4644258760 scopus 로고    scopus 로고
    • Breast cancer in female carriers of ATM gene alterations: Outcome of adjuvant radiotherapy
    • DOI 10.1016/j.radonc.2004.07.010, PII S0167814004003184
    • Meyer A, John E, Dork T, et al. Breast cancer in female carriers of ATM gene alterations: outcome of adjuvant radiotherapy. Radiother Oncol 2004 ; 72 : 319-23. (Pubitemid 39265386)
    • (2004) Radiotherapy and Oncology , vol.72 , Issue.3 , pp. 319-323
    • Meyer, A.1    John, E.2    Dork, T.3    Sohn, C.4    Karstens, J.H.5    Bremer, M.6
  • 42
    • 0035860970 scopus 로고    scopus 로고
    • Outcomes of adjuvant radiation therapy for breast cancer in women with ataxia-telangiectasia mutations [2]
    • Su Y, Swift M. Outcomes of adjuvant radiation therapy for breast cancer in women with ataxia-telangiectasia mutations. JAMA 2001 ; 286 : 2233-4. (Pubitemid 33063141)
    • (2001) Journal of the American Medical Association , vol.286 , Issue.18 , pp. 2233-2234
    • Su, Y.1    Swift, M.2
  • 47
    • 0028823417 scopus 로고
    • Lack of correlation between DNA-dependent protein kinase activity and tumor cell radiosensitivity
    • Allalunis-Turner MJ, Lintott LG, Barron GM, et al. Lack of correlation between DNA-dependent protein kinase activity and tumor cell radiosensitivity. Cancer Res 1995 ; 55 : 5200-2.
    • (1995) Cancer Res , vol.55 , pp. 5200-5202
    • Allalunis-Turner, M.J.1    Lintott, L.G.2    Barron, G.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.