Preparation and characterization of ethosomes for topical delivery of aceclofenac

Indian Journal of Pharmaceutical Sciences

Volumn 72, Issue 5, 2010, Pages 582-586

  Barupal, A K ^a   Gupta, Vandana ^a   Ramteke, Suman ^a  

^a UNIVERSITY INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Aceclofenac; ethosomes; soya lecithin; topical delivery

Indexed keywords

ACECLOFENAC; ALCOHOL; DRUG CARRIER; ETHOSOME; PHOSPHATIDYLCHOLINE; PROPYLENE GLYCOL; UNCLASSIFIED DRUG;

ARTICLE; CELL SHAPE; CELL SIZE; CELL STRUCTURE; CELL VACUOLE; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; DRUG TARGETING; ELECTRON MICROSCOPY; GEL; IN VITRO STUDY; TRANSMISSION ELECTRON MICROSCOPY;

EID: 79955080935     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.78524     Document Type: Article

References (13)

1. Jason DM, Jackson R. Analgesic, antipyretic and anti-inflammatory agents and drugs employed in the treatment of gout. In: Hardman JG, Limbird LE, Gilman AG, editors. The Pharmacological Basis of Therapeutics. 10th ed. New York: McGraw Hill: 2001. p. 711-9.
2. Yamazaki R, Kawai S, Matsuzaki T, Kaneda N, Hashimoto S, Yokokura T, et al. Aceclofenac blocks prostaglandin E2 production following its intracellular conversion into cyclooxygenase inhibitors. Eur J Pharmacol 1997;329:181-7. (Pubitemid 27270532)
3. Pasero G, Marcolongo R, Serni U, Parnham MJ, Ferrer F. A multicentre, double-blind comparative study of the effi cacy and safety of aceclofenac and diclofenac in the treatment of rheumatoid arthritis. Curr Med Res Opin 1995;13:305.
4. Heyneman CA, Lawless-Liday C, Wall GC. Oral versus topical NSAIDs in rheumatic diseases: a comparison. Drugs 2000;60:555-74.
5. Schreir H, Bouwstra J. Liposome and niosomes as topical drug carriers, dermal and transdermal drug delivery. J Control Release 1994;30:1-15.
6. Cevc G, Blume G, Schatzlein A. In vivo Transfersomes mediated transepidermal delivery improves regiospecifi city and biological activity of corticosteroids. J Control Release 1997;45:211-26.
7. Paolino D, Lucania G, Mardente D, Alhaique F, Fresta M. Ethosomes for skin delivery of ammonium glycyrrhizinate: In vitro percutaneous permeation through human skin and in vivo anti-infl ammatory activity on human volunteers. J Control Release 2005;106:99-110. (Pubitemid 41140085)
8. Dayan N, Touitou E. Carriers for skin delivery of trihexyphenidyl HCl: Ethosomes vs. liposomes. Biomaterials 2000;21:1879-85. (Pubitemid 30398506)
9. Lodzki M, Godin B, Rakou L, Mechoulam R, Gallily R, Touitou E. Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. J Control Release 2003;93:377-87. (Pubitemid 37485959)
10. Godin B, Touitou E. Mechanism of bacitracin permeation enhancement through the skin and cellular membranes from an ethosomal carrier. J Control Release 2004;94:365-79. (Pubitemid 38117147)
11. Elsayed MM, Abdallah OY, Naggar VF, Khalafallah NM. Deformable liposomes and ethosomes: mechanism of enhanced skin delivery. Int J Pharm 2006;322:60-6. (Pubitemid 44348860)
12. Touitou E, Godin B, Dayan N, Weiss C, Piliponsky A, Levi-Schaffer F. Intracellular delivery mediated by an ethosomal carrier. Biomaterials 2001;22:3053-9. (Pubitemid 32768713)
13. Touitou E, Dayan N, Bergelson L, Godin B, Eliaz M. Ethosomes - novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Release 2000;65:403-18. (Pubitemid 30122942)