Aceclofenac blocks prostaglandin E2 production following its intracellular conversion into cyclooxygenase inhibitors

European Journal of Pharmacology

Volumn 329, Issue 2-3, 1997, Pages 181-187

  Yamazaki, Ryuta ^a   Kawai, Shinichi ^b   Matsuzaki, Takeshi ^a   Kaneda, Norimasa ^a   Hashimoto, Shusuke ^a   Yokokura, Teruo ^a   Okamoto, Renzo ^c   Koshino, Tomihisa ^c   Mizushima, Yutaka ^b  

^a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Aceclofenac; Cyclooxygenase; Monocyte; Polymorphonuclear leukocyte; Prostaglandin E2; Synovial cell

Indexed keywords

ACECLOFENAC; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DICLOFENAC; DRUG METABOLITE; INDOMETACIN; INTERLEUKIN 1BETA; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; RADIOISOTOPE;

ANIMAL TISSUE; ARTICLE; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATORY CELL; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RHEUMATOID ARTHRITIS; SEMINAL VESICLE; SHEEP; SYNOVIOCYTE;

EID: 0030922754     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)89179-0     Document Type: Article

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